This study was to investigate the association of developmental dysplasia of the hip (DDH) and primary protrusion acetabuli (PPA) with Vitamin D receptor polymorphisms TaqI and FokI and oestrogen receptor polymorphisms Pvu II and XbaI. 45 patients with DDH and 20 patients with PPA were included in the study. Healthy controls (n=101) aged 18-60 years were recruited from the same geographical area. The control subjects had a normal acetabular morphology based on a recent pelvic radiograph performed for an unrelated cause. DNA was obtained from all the subjects from peripheral blood. Genotype frequencies were compared in the three groups. The relationship between the genotype and morphology of the hip joint, severity of the disease, age at onset of disease and gender were examined.Introduction
Methods
The treatment of those fractures varies from conservative treatment, posterior plate fixation, anterior plating as well as percutaneous and open Sacroiliac (SI) joint screws. However, screw pull-outs and loss of fixation in those methods are well described In the Alfred Hospital, Melbourne (Australia) a Level 1 Trauma Center a series of 14 patients were treated from 10/2006 to date with a multiaxial spinal system.
A pedicel screw from a multiaxial spinal system (Xia, Stryker or Pangea, Synthes) is placed percutaneously in the posterior iliac crest on both sides and the reduction is performed with the screws attached to the screw handles and with Image Intensifier. After the reduction the multiaxial screwheads are bent and transfixed with a bar which is tunneled epifacial. All patients underwent a multislice pelvic and lumbar spine CT and these patients were assessed clinically for neurovascular symptoms and stability. The follow-up included clinical assessment and CT imaging.
The follow up time was one to 18 month. The patients were assessed clinically and with CT imaging. No complications or loss of fixation have been observed in this patient group in this short follow up time.
The construct provides initial stability and allows mobilization of the patient. It can be used in cases with sacral comminution and may offer advantages over posterior plate fixation, by reducing complications with prominent metalware.
Pelvic fractures in multi-trauma patients are an indicator of severe trauma and often require advanced wound management of pelvic, abdominal or extremity injuries. Poor wound management may result infected pelvic hardware, necessitating revision surgery. We propose that TNP is a safe method of wound management and report our experience. In 2006 91 multi-trauma patients required pelvic/ace-tabular fixation at The Alfred, either internal or external. Of those, 23 needed TNP for wound care of pelvic, abdominal or extremity injuries. Indications for TNP included Morel-Lavelle lesions, concomitant bladder disruption with anterior wounds, severe edema preventing any wound closure, extremity open fractures/degloving/fasciotomies and post-op infections. The average age of the group was 33, the average injury severity score was 36, 5 were female, 18 were male. There was one pelvic wound infection that resolved with TNP and local wound care. Two unsalvageable limbs (one transhumeral, one transfemoral) required amputation after TNP, all others were either closed primarily or with a flap and skin graft. There was one death in the group from unrelated causes. Pelvic scores, SF-12, visual analog pain scores and sexual dysfunction rates are being gathered and will be reported. Topical negative pressure is a safe and effective method of managing complex wounds in multi-trauma patients with pelvic injuries.