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VERTEBROPLASTY IN OSTEOPOROTIC FRACTURES



Abstract

Our objective is to perform a prospective study on the efficiency and durability of pain reduction through percutaneous PMMA vertebroplasty in patients with vertebral osteoporotic fractures.

We started in March 2002, and up to January 2005 we have performed this technique in 43 patients, 42 female and 1 male, with osteoporotic vertebral fractures. We performed a total of 56 vertebroplasties, 36 lumbar and 20 thoracic. The majority is for the thoracolumbar junction. Patient age went from 56 to 85, with an average of 70,7 years.

Cryteria for inclusion in this study have been the following:patients with osteoporosis, preferably with one or two collapsed vertebral bodies, with intractable pain for over 3 months. Exclusion cryteria have been: infection, blood coagulation deficits and mieloradicular compression. Relative exclusion criteria are Fractures over 70% body collapse, Posterior wall fragmentation and Young patient fracture with no prior disease.

We perform our PV under local anesthaesia with sedation and in a lateral decubitus position. We preferably use a parapedicular approach for both thoracic and lumbar fractured vertebrae.

The material we prefer are the LP2 system or the LCO and we chose Exolent spine for PMMA.

We follow a protocol that consists in:bed rest for 2 hours, allowing the patient to sit and have small walks afterwards;Dismissal the following day, with a mild analgesic for the effects of the skin incision;Maintain drug treatment for osteoporosis;Revision on the 2nd and 7th day;New revision at 3, 6 and 12 months.

Evaluation of the results was made by defining a pain score: Score 1 corresponds to minor or no improvement in pain.

Score 2 corresponds to a medium improvement in pain, with 25 to 50% less drugs required.

Score 3 corresponds to a better improvement in pain, with 75 % less drugs required.

Score 4 corresponds to complete relief of pain. In our revision, we had a minimum follow-up of 12 months, maximum of 44, and an average of 28 months. We have observed the following results:

  • - 2 patients with score 1

  • - 4 patients with score 2

  • - 32 patients with score 3

  • - 5 patients with score 4

We can resume this by stating that 90 % of the patients had a relief in pain, and a good result was observed in 75 %.

We have had some complications, which consisted in:

  • - PMMA leakage into the disc in 1 case

  • - Transitory radicular pain in 1 case

  • - Hiperthermia in 1 case

  • - Cannula breakage in 1 case, which was resolved through a small incision. None of these has altered the final result.

  • - Venous leakage in 1 case, which we have considered as the only serious complication..

In conclusion, and up to now, we have obtained pain reduction in 90% of the cases; we have prevented collapse of the treated vertebrae, and we have not had collapse of any adjacent vertebrae.

It is a technique that may have complications, but results depend on a correct selection of patients.

Correspondence should be addressed to Ms Larissa Welti, Scientific Secretary, EFORT Central Office, Technoparkstrasse 1, CH-8005 Zürich, Switzerland