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Hip

WEAR ANALYSIS OF TAPERS FROM FAILED METAL-ON-POLYETHYLENE HIPS PROVIDES FIRST DATA ON CLINICALLY SIGNIFICANT DOSES OF COBALT AND CHROMIUM FOR ADVERSE REACTION TO METAL DEBRIS

British Hip Society meeting (BHS) March 2017



Abstract

Trunnionosis, due to mechanical wear and/or corrosion at the head stem taper junction, can occur in metal on polyethylene (MOP) hip implants. In some patients this results in severe soft tissue destruction or Adverse Reaction to Metal Debris (ARMD). The amount of material required to cause ARMD is unknown but analyses of retrieved hips may provide the answer to this clinically important question.

We collected implants from 20 patients with failed hips with MOP bearings, revised due to ARMD. We collected clinical, imaging and blood test data. We graded the severity of taper corrosion (1 to 4), and quantified the volume of material loss from this junction. We compared our results with previous data collected for metal-on-metal (MOM) hips.

The median time to revision of the MOP hips was 51.3 (23.1–56.4) months. All head tapers were moderately to severely corroded with a median corrosion score of 4. The median (range) of total material loss at the taper of the MOP hips was 3.9 mm3 (2.96 – 7.85 mm3) and the material loss rate was 1.4 mm3 / year (0.56 – 1.82).

Comparison with MOM hips revealed no significant difference in taper material loss (p=0.7344) with a median rate of 0.81 mm3 / year (0.01–3.45).

We are the first to quantify the volume of material loss at the head taper of hip implants with MOP bearings that were revised due to trunnionosis. This data indicates that a clinically significant dose of cobalt and chromium to induce ARMD is approximately 1.4 mm3 / year.

We have identified a clinically significant volume of taper material loss in MOP hips.


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