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Bone & Joint Open
Vol. 2, Issue 6 | Pages 397 - 404
1 Jun 2021
Begum FA Kayani B Magan AA Chang JS Haddad FS

Limb alignment in total knee arthroplasty (TKA) influences periarticular soft-tissue tension, biomechanics through knee flexion, and implant survival. Despite this, there is no uniform consensus on the optimal alignment technique for TKA. Neutral mechanical alignment facilitates knee flexion and symmetrical component wear but forces the limb into an unnatural position that alters native knee kinematics through the arc of knee flexion. Kinematic alignment aims to restore native limb alignment, but the safe ranges with this technique remain uncertain and the effects of this alignment technique on component survivorship remain unknown. Anatomical alignment aims to restore predisease limb alignment and knee geometry, but existing studies using this technique are based on cadaveric specimens or clinical trials with limited follow-up times. Functional alignment aims to restore the native plane and obliquity of the joint by manipulating implant positioning while limiting soft tissue releases, but the results of high-quality studies with long-term outcomes are still awaited. The drawbacks of existing studies on alignment include the use of surgical techniques with limited accuracy and reproducibility of achieving the planned alignment, poor correlation of intraoperative data to long-term functional outcomes and implant survivorship, and a paucity of studies on the safe ranges of limb alignment. Further studies on alignment in TKA should use surgical adjuncts (e.g. robotic technology) to help execute the planned alignment with improved accuracy, include intraoperative assessments of knee biomechanics and periarticular soft-tissue tension, and correlate alignment to long-term functional outcomes and survivorship.


Bone & Joint Open
Vol. 3, Issue 5 | Pages 390 - 397
1 May 2022
Hiranaka T Suda Y Saitoh A Tanaka A Arimoto A Koide M Fujishiro T Okamoto K

The kinematic alignment (KA) approach to total knee arthroplasty (TKA) has recently increased in popularity. Accordingly, a number of derivatives have arisen and have caused confusion. Clarification is therefore needed for a better understanding of KA-TKA. Calipered (or true, pure) KA is performed by cutting the bone parallel to the articular surface, compensating for cartilage wear. In soft-tissue respecting KA, the tibial cutting surface is decided parallel to the femoral cutting surface (or trial component) with in-line traction. These approaches are categorized as unrestricted KA because there is no consideration of leg alignment or component orientation. Restricted KA is an approach where the periarthritic joint surface is replicated within a safe range, due to concerns about extreme alignments that have been considered ‘alignment outliers’ in the neutral mechanical alignment approach. More recently, functional alignment and inverse kinematic alignment have been advocated, where bone cuts are made following intraoperative planning, using intraoperative measurements acquired with computer assistance to fulfill good coordination of soft-tissue balance and alignment. The KA-TKA approach aims to restore the patients’ own harmony of three knee elements (morphology, soft-tissue balance, and alignment) and eventually the patients’ own kinematics. The respective approaches start from different points corresponding to one of the elements, yet each aim for the same goal, although the existing implants and techniques have not yet perfectly fulfilled that goal.


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_11 | Pages 50 - 50
1 Nov 2022
Nayak M Rambani R
Full Access

Abstract

Background

Although tantalum is a well recognised implant material used for revision arthroplasty, little is known regarding the use of the same in primary total hip arthroplasty.

Methods

A literature search was performed to find all relevant clinical studies until March 2020, which then underwent a further selection criteria. The inclusion criteria was set as follows: Reporting on human patients undergoing primary total hip arthroplasty; Direct comparison between tantalum acetabular cups with conventional acetabular cups

for use in primary total hip arthroplasty; Radiological evaluation (cup migration, osteointegration); Clinical (functional scores, need for subsequent revision, patient-reported outcomes; Post-operative complications; Reporting findings in the English Language. After a thorough search a total of six studies were included in the review. The primary outcome

measures were clinical outcomes, implant migration, change in bone mineral density and rate of revision and infection.


Bone & Joint Open
Vol. 3, Issue 1 | Pages 85 - 92
27 Jan 2022
Loughenbury PR Tsirikos AI

The development of spinal deformity in children with underlying neurodisability can affect their ability to function and impact on their quality of life, as well as compromise provision of nursing care. Patients with neuromuscular spinal deformity are among the most challenging due to the number and complexity of medical comorbidities that increase the risk for severe intraoperative or postoperative complications. A multidisciplinary approach is mandatory at every stage to ensure that all nonoperative measures have been applied, and that the treatment goals have been clearly defined and agreed with the family. This will involve input from multiple specialities, including allied healthcare professionals, such as physiotherapists and wheelchair services. Surgery should be considered when there is significant impact on the patients’ quality of life, which is usually due to poor sitting balance, back or costo-pelvic pain, respiratory complications, or problems with self-care and feeding. Meticulous preoperative assessment is required, along with careful consideration of the nature of the deformity and the problems that it is causing. Surgery can achieve good curve correction and results in high levels of satisfaction from the patients and their caregivers. Modern modular posterior instrumentation systems allow an effective deformity correction. However, the risks of surgery remain high, and involvement of the family at all stages of decision-making is required in order to balance the risks and anticipated gains of the procedure, and to select those patients who can mostly benefit from spinal correction.


Bone & Joint 360
Vol. 5, Issue 5 | Pages 2 - 7
1 Oct 2016
Forward DP Ollivere BJ Ng JWG Coughlin TA Rollins KE

Rib fracture fixation by orthopaedic and cardiothoracic surgeons has become increasingly popular for the treatment of chest injuries in trauma. The literature, though mainly limited to Level II and III evidence, shows favourable results for operative fixation. In this paper we review the literature and discuss the indications for rib fracture fixation, surgical approaches, choice of implants and the future direction for management. With the advent of NICE guidance and new British Orthopaedic Association Standards for Trauma (BOAST) guidelines in production, the management of rib fractures is going to become more and more commonplace.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_6 | Pages 97 - 97
1 Mar 2017
Widmer K
Full Access

Introduction

Lewinnek's Safe-Zone gives recommendations only for cup placement in total hip arthroplasty while the orientation of the neck isn't considered. Furthermore the criteria for cup placement are not clearly defined and the ranges for cup orientation are considerably large. This study introduces new recommandations for the combined placement of both total hip components, when both, cup and stem, are considered. This defines the new dynamic combined safe-zone (cSafe-Zone) which gives clear directions for the optimal combined orientation of both components in order to maximize the intended range of movement (iROM) while reducing the risk for prosthetic impingement and dislocation.

Material and Methods

The combined safe-zone outlines the area that encloses all component orientations that achieve the predefined iROM without prosthetic impingement. A computerized 3D-model of a total hip prosthesis was established that does systematically test all design parameters semi-automatically in order to identify those component positions that fulfill the predefined conditions. The analysis was carried out for straight stems, anatomic stems and short stems. The iROM is composed of basic movements like flexion/extension, internal/external rotation, ab/adduction and combination of these movements that the patient should reach and that are commonly accepted as physiologic hip movements. The orientation of the cup was varied between 20° and 70° of inclination and −10° of retro- to 40° anteversion. Stem antetorsion was tested from −10° retro- to 40°-antetorsion and CCD-angle from 110° to 150°. Head-size and head/neck ratio were additional parameters.


Bone & Joint Open
Vol. 5, Issue 7 | Pages 565 - 569
9 Jul 2024
Britten S

Two discrete legal factors enable the surgeon to treat an injured patient the fully informed, autonomous consent of the adult patient with capacity via civil law; and the medical exception to the criminal law. This article discusses current concepts in consent in trauma; and also considers the perhaps less well known medical exception to the Offences against the Person Act 1861, which exempts surgeons from criminal liability as long as they provide ‘proper medical treatment’. Cite this article: Bone Jt Open 2024;5(7):565–569


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_17 | Pages 77 - 77
1 Dec 2018
Pesch S Kirchhoff C van Griensven M Biberthaler P Hanschen M Huber-Wagner S
Full Access

Aim. The current treatment concepts of acute and chronic osteomyelitis are associated with unsolved challenges and problems, underlining the need for ongoing medical research. The invention and prevalence of an absorbable, gentamicin-loaded ceramic bone graft, that is well injectable for orthopedic trauma and bone infections, enlarges the treatment scope regarding the rise of posttraumatic deep bony infections. This substance can be used either for infection, dead-space, or reconstruction management. The bone cement, eluting antibiotics continuously to the surrounding tissue, outperforms the intravenous antibiotic therapy and enhances the local concentration levels efficiently. This study aims to evaluate the power and practicability of bone cement in several locations of bony infections. Method. The occurrence of posttraumatic infections with acute or chronic osteomyelitis increases in trauma surgery along with progression of high impact injuries and consecutively high incidence of e.g. open fractures. We present a case-series of 33 patients (18w/15m; 56,8±19,4 years) with posttraumatic osteomyelitis at different anatomic sites, who were treated in our level I trauma center. All of these patients received antibiotic eluting bone cement (Cerement® G) for infection and reconstruction management. Results. With admission to our trauma-center all patients with obvious or suspected osteomyelitis undergo an interdisciplinary pre-work up, including thorough clinical examination and different measures of diagnostic imaging, ultimately leading to the definition of an individual treatment plan. We diagnosed 33 bone infections anatomically allocated to the proximal and distal femur (12x), the pelvis (2x), distal tibia (3x), tibial diaphysis (10x), the ankle joint (4x) and calcaneus (2x). According to Cierny-Mader we diagnosed grade I (6), II (7), III (13) and IV (7). These 33 patients were treated (1) with surgical debridement, (2) with Cerament G, (3) bone stabilisation (including nail osteosynthesis, arthrodesis nails, plates, or external ring fixation), (4) optionally VAC-conditioning, and (5) optionally soft tissue closure with local or free flaps. The overall number of surgery was 2.9±2.26. We observed very good clinical, functional and radiological results by using bone cement augmented with gentamicin. The overall recurrence rate of infection is low (12%, 4/33). “White fluid” secretion was observed in six cases. Conclusions. Current concepts for treatment of osteomyelitis include radical surgical debridement and additional antibiotic therapy. It could be demonstrated that the usage of an antibiotic biocement with osteoconductive characteristics enlarges the success rate in septic bone surgery. The treatment concepts, however, remain complex, time consuming, require a high patient compliance, and are highly individually


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_22 | Pages 79 - 79
1 Dec 2017
Huber-Wagner S Pesch S Kirchhoff C Griensven M Biberthaler P Hanschen M
Full Access

Aim. The current treatment concepts of acute and chronic osteitis are associated with unsolved challenges and problems, underlining the need for ongoing medical research. The invention and prevalence of an absorbable, gentamicin-loaded ceramic bone graft, that is well injectable for orthopedic trauma and bone infections, enlarges the treatment scope regarding the rise of posttraumatic deep bone infections. This substance can be used either for infection, dead-space, or reconstruction management. The bone cement, eluting antibiotics continuously to the surrounding tissue, outperforms the intravenous antibiotic therapy and enhances the local concentration levels efficiently. This study aims to evaluate the power and practicability of bone cement in several locations of bone infections. Method. The occurrence of posttraumatic infections with acute or chronic osteitis increases in trauma surgery along with progression of high impact injuries and consecutively high incidence of e.g. open fractures. We present a case-series of 10 patients with posttraumatic osteitis at different anatomic sites, who were treated in our level I trauma center. All of these patients received antibiotic eluting bone cement* for infection and reconstruction management. Results. With admission to our trauma-center all patients with obvious or suspected osteitis undergo an inter-disciplinary pre-work up, including thorough clinical examination and different measures of diagnostic imaging, ultimately leading to the definition of an individual treatment plan. We diagnosed 10 bone infections anatomically allocated to the proximal (2x) and distal femur (3x), distal tibia (3x), tibial diaphysis (1x) and the ankle joint (1x). These ten patients were treated (1) with surgical debridement, (2) with an antibiotic eluting bone cement*, (3) bone stabilisation (including nail osteosynthesis, arthrodesis nails, plates, or external ring fixation), (4) optionally VAC-conditioning, and (5) optionally soft tissue closure with local or free flaps. We observed very good clinical, functional and radiological results by using bone cement augmented with gentamicin. The overall treatment failure rate is low, throughout, all patients showed no signs of acute recurrence of infection. Pain and immobility decreased continuously with time. “White fluid” secretion was observed in one case. Conclusion. Current concepts for treatment of osteitis include radical surgical debridement and additional antibiotic therapy. It could be demonstrated that the usage of an antibiotic biocement with osteoconductive characteristics enlarges the success rate in septic bone surgery. The treatment concepts, however, remain complex, time consuming, require a high patient compliance, and are highly individually. *Cerement® G


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_17 | Pages 8 - 8
1 Nov 2016
Gobezie R
Full Access

Total shoulder arthroplasty results in excellent outcomes for most patients who suffer from osteoarthritis of the shoulder. Current trends within the field reflect a desire to minimise stem lengths in contemporary prosthetic designs. The movement towards short-stem humeral implants proffers several advantages including the ease of revision and ‘less invasive’ surgery. But, is there data to support these claims? This talk will focus on the proposed advantages of short-stem implants, variations in the current designs, the data on their outcomes and other current concepts with these implants


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_5 | Pages 117 - 117
1 Mar 2017
Riviere C Howell S Parratte S Vendittoli P Iranpour F Cobb J
Full Access

The mechanical alignment (MA) for Total Knee Arthroplasty (TKA) with neutral alignment goal has had good overall long-term outcomes. In spite of improvements in implant designs and surgical tools aiming for better accuracy and reproducibility of surgical technique, functional outcomes of MA TKA have remained insufficient. Therefore, alternative, more anatomicaloptions restoring part (adjusted MA (aMA) and adjusted kinematic alignment (aKA) techniques) or the entire constitutional frontal deformity (unicompartment knee arthroplasty (UKA) and kinematic alignment (KA) techniques) have been developed, with promising results. The kinematic alignment for TKA is a new and attractive surgical technique enabling a patient specific treatment. The growing evidence of the kinematic alignment mid-term effectiveness, safety and potential short falls are discussed in this paper. The current review describes the rationale and the evidence behind different surgical options for knee replacement, including current concepts in alignment in TKA. We also introduce two new classification systems for “implant alignments options” (Figure 1) and “osteoarthritic knees” (Figure 2) that would help surgeons to select the best surgical option for each patient. This would also be valuable for comparison between techniques in future research. For figures/tables, please contact authors directly.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_2 | Pages 65 - 65
1 Jan 2017
Rivière C Iranpour F Cobb J Howell S Vendittoli P Parratte S
Full Access

The mechanical alignment (MA) for Total Knee Arthroplasty (TKA) with neutral alignment goal has had good overall long-term outcomes. In spite of improvements in implant designs and surgical tools aiming for better accuracy and reproducibility of surgical technique, functional outcomes of MA TKA have remained insufficient. Therefore, alternative, more anatomical options restoring part (adjusted MA (aMA) and adjusted kinematic alignment (aKA) techniques) or the entire constitutional frontal deformity (unicompartment knee arthroplasty (UKA) and kinematic alignment (KA) techniques) have been developed, with promising results. The kinematic alignment for TKA is a new and attractive surgical technique enabling a patient specific treatment. The growing evidence of the kinematic alignment mid-term effectiveness, safety and potential short falls are discussed in this paper. The current review describes the rationale and the evidence behind different surgical options for knee replacement, including current concepts in alignment in TKA. We also introduce two new classification systems for “implant alignments options” and “osteoarthritic knees” that would help surgeons to select the best surgical option for each patient. This would also be valuable for comparison between techniques in future research


Bone & Joint Open
Vol. 4, Issue 7 | Pages 516 - 522
10 Jul 2023
Mereddy P Nallamilli SR Gowda VP Kasha S Godey SK Nallamilli RR GPRK R Meda VGR

Aims

Musculoskeletal infection is a devastating complication in both trauma and elective orthopaedic surgeries that can result in significant morbidity. Aim of this study was to assess the effectiveness and complications of local antibiotic impregnated dissolvable synthetic calcium sulphate beads (Stimulan Rapid Cure) in the hands of different surgeons from multiple centres in surgically managed bone and joint infections.

Methods

Between January 2019 and December 2022, 106 patients with bone and joint infections were treated by five surgeons in five hospitals. Surgical debridement and calcium sulphate bead insertion was performed for local elution of antibiotics in high concentration. In all, 100 patients were available for follow-up at regular intervals. Choice of antibiotic was tailor made for each patient in consultation with microbiologist based on the organism grown on culture and the sensitivity. In majority of our cases, we used a combination of vancomycin and culture sensitive heat stable antibiotic after a thorough debridement of the site. Primary wound closure was achieved in 99 patients and a split skin graft closure was done in one patient. Mean follow-up was 20 months (12 to 30).


Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_19 | Pages 25 - 25
1 Dec 2014
Obert L Jardin E Loisel F Adam A Uhring J Rochet S Lascar T
Full Access

Introduction:. 90 cases of reversed prosthesis have been evaluated and the aim of the retrospective multicenter study was to correlate the functional and radiological results depending on the type of implant. Material & Methods:. 90 patients have been operated (67 eccentric omarthrosis, 5 centered omarthrosis, 7 massive rotator cuff tear, 11 others), by 8 surgeons in 3 centers by a delto-pectoral approach (71%), and evaluated retrospectively by an independant surgeon. 3 types of prosthesis have been implanted: 1st generation of reversed prosthesis (Aequalis-Reversed, Tornier®: humeral neck angle of 155°), BioRSA (humeral neck angle of 155° but with lateralization of center of rotation, Tornier®), and a prosthesis with a more vertical angle of 145° (Humelock-Reversed, FX-Solutions®. A prospective study of the QuickDash score, Constant score and analysis of clinical and radiological complications by the surgeon and an independant surgeon at the time of longest follow up is reported. Results:. 76/90 patients have been reviewed with a mean follow up of 18,4 months (15,6% loss of FU). The mean Constant score of the series reached 55,1 (78,2 with ponderation). In this series 59,2% of radiological complications (35,5% of notch) and 14,5% of clinical complications were reported. Mobility and functional scores were not different depending on the type of implant but were significantly better in the group of prostheses implanted after 2012 than before 2010. Only one significant difference has been noted: in the subgroup of implants with a more vertical humeral angle (Humelock-Reversed, FX-Solutions® 145°) there was no notching at FU (versus 57% in the 2 other groups). Discussion:. Learning curve and technical modifications on each implant allows improved results of each published series of reversed prosthesis. Even if each notch is not followed in each patient by diminution of functional results, each surgeon has to offer to his own patient the lower risk to develop a notch. Conclusion:. Following the current concept the best way to decrease the notch in reversed prosthesis seems to combine an inferior tilt, a low implantation of metaglene, and a more vertical humeral angle


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIII | Pages 158 - 158
1 May 2012
Robinson M
Full Access

Michael Robinson has been a Consultant Orthopaedic Surgeon and Senior Lecturer in the Department of Orthopaedics and Traumatology in Edinburgh, Scotland, United Kingdom for 10 years. His special interests include the treatment of proximal humeral and clavicle fractures, and shoulder instability. The majority of proximal humerus fractures can be managed non-operatively with surgery reserved for approximately 10–20% of patients. The choice of surgical treatment is usually between a humeral head head-conserving fracture reduction and internal fixation and humeral head sacrifice hemiarthroplasty. Current indications for primary hemiarthroplasty include a displaced four-part fracture (with or without associated dislocation of the humeral head) and a head-splitting fracture (with involvement of >40% of the articular surface), due to the high associated risk of avascular necrosis. However, the indications for internal fixation of proximal humerus fractures have expanded over the last decade, and many fractures which have previously been considered unsalvageable and treated either non-operatively or with hemiarthroplasty are now deemed reconstructable. This is partially as a result of improved appreciation of sub-groups of fractures which have a better prognosis from head-salvage, the possibility that subsequent development of osteonecrosis may be relatively asymptomatic and the realisation that functional results after hemiarthroplasty are often sub-optimal. The purpose of this talk is to discuss the current concepts in fracture classification and the indications for operative treatment for these fractures. The novel surgical approaches, techniques and implants which have renewed interest in their treatment are also highlighted. None of the authors have received any payment or consideration from any source for the conduct of this study


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIII | Pages 9 - 9
1 May 2012
Licina P
Full Access

To date, the goals of spinal surgery have been easy to define: to ‘decompress’, to ‘realign’ and to ‘fuse’. More recent refinements have been directed towards two new goals: to ‘preserve’ and to ‘protect’. Preservation of the enveloping soft tissues minimises bleeding and scarring, and reduces pain. This can be facilitated by minimal and alternate access surgery, using techniques such as percutaneous pedicle screw insertion, transpsoas and transsacral vertebral access and endoscopic scoliosis correction. Protection of the neural elements improves the safety of spinal surgery and allows the surgeon to perform more complex procedures. Methods have been developed to accurately guide the surgeon to the target structure or pathology while avoiding neural structures, and to monitor spinal cord and nerve function. Both approaches allow safer instrumentation and deformity correction. In the past, protection of important structures has been achieved by wide exposures, sacrificing preservation of soft tissues. As this shortcoming has been recognised, techniques have been developed that have radically reduced wound size but often compromised vision and put neurovascular elements at risk. Refinements have attempted to balance these goals. At present, we have a variety of techniques available to us but were hare hampered by cost and complexity. The future will hopefully bring further improvements but perhaps new ideas and approaches that challenge our current concepts of invasive spinal surgery


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_X | Pages 121 - 121
1 Apr 2012
Jehan S Thambiraj S Sundaram R Boszczyk B
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Literature review about the current management strategies for U-shape sacral fractures. A thorough literature search was carried out to find out the current concepts in the management of U-shaped sacral fractures. Meta-analysis of 30 cases of U-Shaped sacral fractures. Radiological assessment for bone healing, and clinical examination for neurological recovery. 7 papers were published in the English literature between 2001 and 2009 about the management of U-shaped sacral fractures. In total 30 cases were included. The most common mechanism of injury was fall or jump from height (63%), followed by road traffic accidents and industrial injuries. Pre-operative neurological deficit was noted in 73% of patients. The average follow up time ranged from 2-12 months. 18 (60%) of patients were treated with sacroiliac screws. In this group pre-operative neurological deficit was found in 12(66%) patients. All of these patients had satisfactory radiological healing at follow up but 5(27%) patients had residual neurological deficit. No immediate complication was reported in this group. Incomplete sacroiliac screw disengagement was reported in one patient without fixation failure. Other procedures performed were lumbopelvic fixation, triangular osteosynthesis and transsacral plating. The most common cause of U-shaped sacral fractures is a fall or jump from height. There is a high association of neurological damage with U-shaped sacral fractures. From the current available evidence sacroiliac screw fixation is the most commonly performed procedure, it is however not possible to deduce which procedure is better in terms of neurological recovery


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XLIII | Pages 23 - 23
1 Sep 2012
Malik A Wright B Mann B Saini A Solan M
Full Access

Introduction. Foot and ankle is a well-established and growing sub specialty in orthopaedics. It accounts for 20 to 25 per cent of an average department's workload. There are two well established foot and ankle specialist journals but for many surgeons the Journal of Bone and Surgery (JBJS) remains the preeminent journal in orthopaedics and a highly sought after target journal for publication of research. It is our belief that foot and ankle surgery is underrepresented in the JBJS. We undertook a study to test this hypothesis. Methods. We analysed all JBJS (British and American editions) volumes over a 10 year period (2001 to 2010). We recorded how many editorials, reviews, original papers and case reports were foot and ankle related. Results. of 2197 original papers published in JBJS Br only 114 (5%) were foot and ankle related. Nine out of 181 (5%) case reports, 2 out of 71 (3%) aspects of current management, none of the 51 editorials and only 3 out of 97 (3%) of reviews were foot and ankle related. In the JBJS American edition 174 out of 2117 original papers (8%), 28 out of 401 (7%) case reports, 4 out of 103 (4%) current concept reviews, 8 out of 115 (7%) instructional course lectures were foot and ankle related. Of 35 Editors on the JBJS British edition only 2 were dedicated foot and ankle surgeons, one of whom is retired. Our study reveals that foot and ankle related research accounts for a very small proportion of JBJS publications. Foot and ankle surgery needs to be proportionally represented at the editorial board level to reflect the fast growing interest in foot and ankle conditions and related research


The Bone & Joint Journal
Vol. 104-B, Issue 9 | Pages 1011 - 1016
1 Sep 2022
Acem I van de Sande MAJ

Prediction tools are instruments which are commonly used to estimate the prognosis in oncology and facilitate clinical decision-making in a more personalized manner. Their popularity is shown by the increasing numbers of prediction tools, which have been described in the medical literature. Many of these tools have been shown to be useful in the field of soft-tissue sarcoma of the extremities (eSTS). In this annotation, we aim to provide an overview of the available prediction tools for eSTS, provide an approach for clinicians to evaluate the performance and usefulness of the available tools for their own patients, and discuss their possible applications in the management of patients with an eSTS.

Cite this article: Bone Joint J 2022;104-B(9):1011–1016.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_II | Pages 182 - 182
1 Feb 2004
Tsirikos A Chang W Dabney K Miller F Glutting J
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Objective: The aim of this study was to document rate of survival among 288 severely affected pediatric patients with spasticity and neuromuscular scoliosis who underwent spinal fusion and to identify exposure variables that could significantly predict survival times. Methods: Kaplan-Meier survivorship analysis was performed and Cox’s proportional hazards model was used to evaluate predictive efficacy of exposure variables such as gender, age at surgery, level of ambulation, mental ability, degree of coronal and sagittal plane spinal deformity, intraoperative blood loss, surgical time, days in the hospital, and days in the intensive care unit (ICU). Results: The statistical analysis demonstrated a mean predicted survival of 134.3 months (11.2 years) after surgical correction of spinal deformities for this group of globally involved children with cerebral palsy. The number of days in the ICU after surgery and the presence of severe preoperative thoracic hyperkyphosis were the only factors affecting survival rates. ICU stay of greater than five days, which was usually associated with respiratory problems, substantially increasing the risk of death. Thoracic hyperkyphosis of greater than 70o caused a considerable increase in the predicted mortality rate. Conclusions: Our study demonstrated a relatively long mean predicted survivorship for pediatric patients with severe spastic cerebral palsy and neuromuscular scoliosis who underwent spinal surgery, which is consistent with the current concept of increased life expectancy even for the total-body involved patients. The most accurate determinants for survival rates among this population group were the number of days the patient had to spend postoperatively in the intensive care unit, and the presence of excessive preoperative thoracic hyperkyphosis