Background. Fractures of the femoral neck occurring outside the capsule of the hip joint are assumed to have an intact blood supply and hence their conventional management is by fixation rather than arthroplasty. The dynamic hip screw and its variants have been used over many years to fix such fractures but have inherent vulnerabilities; they require an intact lateral femoral cortex, confer a relatively long moment arm to the redistribution of body weight and may cause a stress riser due to the plate with which they are fixed to the femur. Intramedullary devices for fixation of proximal femoral fractures have a shorter moment arm, can be distally locked with reduced perforation of the femoral cortex and are believed to be inherently more stable. For these reasons, a number of surgeons believe them to be superior to the DHS for all extracapsular fractures and their use is now widespread. In this study, we present the usage trends of both devices in extracapsular fractures over the last five years and set these results in the context of patient demographics. Methods. Our departmental electronic patient management system was used to identify all patients undergoing surgery coded as either DHS or its variants or intramedullary fixation of hip fracture. The patients’ age, sex and American Society of Anaesthesiologists grading were recorded. Comparison between groups was made using appropriate tests in SPSS. Results. Our unit has seen a steady move towards the use of intramedullary fixation of extracapsular fractures over five years, from 28.2% to 45.2% of operations, without a change in demographics of the population or a change in surgical outcomes at the most basic level. Conclusion. The move towards intramedullary fixation without evidence of improved outcomes, given the significantly higher cost, requires urgent research. Level of Evidence. IV

Aim: To compare extracapsular and intracapsular proximal femoral fractures in terms of pain scores, morbidity, mortality and total stay in hospital. Method: A prospective study over a 8 month period at a regional trauma centre. 170 patients over 60 years of age were included and their mean age was 82.6 years. Pain scores were recorded daily using a visual analogue scale. Results: Extracapsular fractures are more painful (p< 0.01 Mann-Whitney), associated with greater morbidity (p< 0.05 Chi-square, Fishers Exact) and are slower to recover (p< 0.01 Mann-Whitney) compared to intracapsular proximal femoral fractures. There was less mortality associated with undisplaced intracapsular fractures compared to all others (p< 0.01 Mann-Whitney). Conclusions: trochanteric proximal femoral fractures are more problematic medically and as such require more medical, nursing and resource input compared to intracapsular fractures. This knowledge can be used by the clinician to anticipate greater morbidity and as such treat more promptly

Introduction and purpose: Cases of unstable extracapsular fractures of the proximal femur should be treated by endomedullary nailing; the PFN (Synthes) nail has proved to be a good option for this approach. The purpose of our paper is to make a descriptive study analyzing the medical and technical complications derived from the use of the PFN nail. Materials and methods: This study reviews a consecutive series of 432 patients implanted with a PFN, out of whom 352 have had a follow-up longer than 6 months. Mean age is 76.3 years and the male/female ratio is 2:1. An analysis was made of the variables related to medical complications inherent in the fracture itself and in the patient characteristics (AO fracture type, ASA surgical risk, organic complications, infection risk factors, duration of hospital stay and mortality) and to secondary mechanical complications caused by implant design or the surgical technique chosen (implant protrusions, system cutting out, osteolysis and intraoperative and postoperative fractures propagated from the tip of the implant). Results: We performed a frequency analysis and an exponential chi square study which told us that the most frequent fracture was type A2 (AO classification) and the most frequent patient type was ASA III (ASA classification). Mean hospital stay was 6.66 days. During follow-up, medical complications were 17.5% and mechanical ones 11%. Conclusions: The PFN nail is an efficient means for treating extracapsular fractures of the proximal femur although its use is not free from complications, which could be minimized by employing a careful surgical technique. We found that there is a direct relationship between surgical success and patient ASA type

Background: Extracapsular fractures of proximal femur are known to have a significatively high morbidity and mortality rate at one year, and this rate is higher in case of non operative treatment. The standard gamma nail (SGN) was originally designed to provide a stable implant which allows early mobilisation and weight bearing of the elderly patients. The design of SGN however, appeared to be associated with intraoperative or postoperative femoral shaft fractures in up to 17%, requiring further surgery and compromising the outcome in these elderly patients. The trochanteric nail (TGN) was developed to overcome the problems encountered with the use of the SGN. We report our experience in the use of the TGN in the treatment of extracapsular fractures of proximal femur. Methods: Between December 1999 and January 2001, eighty-seven consecutive patients with an extra-capsular fracture of the femur (in one case bilateral) and one patient with a proximal femoral metastasis were treated with a TGN. Nine patients died within four months of the operation and 3 were lost at follow-up. Seventy-five patients, for a total of 76 fractures were followed clinically and radiographically until the end of treatment, for a mean follow-up period of 10 months. Results: In none of 88 cases did an intraoperative shaft femur fracture occur, nor was this complication observed in the 76 femurs evaluated at follow-up. Postoperative infection was never found and union was achieved in every case. Two cases of cutting-out were reported and both were caused by incorrect placement of implant. Only nine patients (12%) required two crutches or walker at the last follow-up. Conclusion: The TGN is a promising alternative for the treatment of extracapsular fractures of the proximal femur. This implant enables the surgeon to treat most of intertrochanteric and high subtrochanteric fractures with a less invasive technique, and permits early mobilisation and unprotected weight-bearing, without the complications observed with the use of the SGN

Introduction: Many patients admitted to acute fracture units with femoral neck fractures are frail and elderly, dehydrated and malnourished, often with associated medical conditions. Surgery may be delayed for investigation, prolonged management and inadequate review of their medical problems, leading to clinical deterioration with poor outcome. Local anaesthetic techniques have been described for intracapsular fractures. We describe a technique effective for the treatment of the more difficult extracapsular type. Aims: To provide a safe and effective technique using local anaesthetic and sedation, for the insertion of a dynamic hip screw in high risk elderly patients with extracapsular femoral neck fractures. Method: Fifty elderly patients who sustained an inter-trochanteric fracture of their femoral neck underwent dynamic hip screw insertion under local anaesthetic and sedation. These patients were medically assessed following admission, all were ASA grade 4, had an additional medical condition (recent MI, CVA, chest infection, aortic stenosis) and were deemed unfit for either general or spinal anaesthesia. All patients not fit for traditional anaesthetic methods were assessed for their suitability for operation under LA, consented and placed on the next available theatre list. A femoral nerve block was performed, with the aid of a nerve stimulator for accurate location, in the anaesthetic room; skin and periosteal infiltration was performed using a 22g spinal needle, with caution to include the distribution of the lateral cutaneous nerve. The patient was then placed on the fracture table and mild sedation (Ketamine, Diazemul, 02/N20) was administered, titrated against the patients requirements. The fracture was reduced using traction and internal rotation, and the DHS inserted. Local Anaesthetic:Infiltration; * 20mls O.25% marcaine/1 in 200,000 adrenaline diluted to 40mls with sterile water. (30mls used with 10mls reserved) * 20mls 1% lidocaine diluted in 40mls of sterile water. (10mls used for skin). Local Anaesthetic femoral nerve block; * 10mls 0.25% plain marcaine. The combined amount of local anaesthetic used is well below safe limits recommended by the World Federation of Societies of Anaesthesiologists. Conclusion: This technique is a safe, simple and effective method of allowing high risk, medically unfit patients to undergo surgery. It reduces operative bleeding and postoperative analgesia requirements, no peri-operative deaths occurred and one patient had evidence of post operative tachycardia that settled within 12 hours

Introduction and Objectives: Our aim is to study the effects of these two factors on functional recovery of patients undergoing surgery for extracapsular hip fracture. Materials and Methods: A multi-centre study involving 3 hospitals was done on 163 patients presenting with extracapsular hip fractures who were treated using IMHS sliding nail/screws. Six months of postoperative follow-up was done to evaluate Charlson’s index comorbidity, pre-fracture functionality,and postoperative functionality at 3 and 6 months using Parker and Palmer’s test and the hospitalization index. Functional progression was evaluated in terms of comorbidity using comparison of means. To study the impact of hospitalisation, a comparision of mean scores for hospitalised and non-hospitalised patients was performed. Results: The final analysis was done using data from 127 patients. Of this sample, 109 patients were not hospitalised before the fracture, and 18 had been hospitalised. There were no significant differences in average Charlson’s index scores between hospitalised and non-hospitalised patients. Functionality at 3 months was 3.97 for non-hospitalised patients and 2.0 for hospitalised patients; at 6 months scores were 4.56 for non- hospitalised patients and 2.38 for hospitalised (p< 0.005). Patients with a Charlson score greater than 2 had a loss of function of 2.16 points at 3 months and 1.58 at 6 months (p< 0.005). Patients with a Charlson score less than or equal to 2 had a functional loss of 1.82 points at 3 months and 1.26 at 6 months (p< 0.005). Discussion and Conclusions: Hospitalised patients had greater loss of function than non-hospitalised patients, independent of their previous health status. Patients with greater comorbidity had greater loss of function compared to patients with less severe previous pathology

Purpose of the study: The constantly increasing incidence of extracapsular fractures of the proximal femur are a public health concern. The basic therapeutic options are screw-plate fixation and proximal reconstruction with nails. The purpose of this retrospective study was to assess the mid-term results with a new osteosynthesis material, the proximal femoral nail antirotation (PFN-A. ®. ) which has a spiral blade. Material and methods: One hundred eight 108 PNF-A. ®. performed from January 2007 to July 2008 were included in a retrospective clinical and radiographic study. These series included exclusively extracapsular fractures of the proximal femur in subjects aged over 70 years. All patients were assessed with the Parker score pre- and postoperatively. Blood loos, position of the spiral blade on the AP and laterals views and operative time were analysed. We searched for complications (femoral head slide, blade protrusion, head rotation, non-union, fracture on material, and operative site infection). We searched for risk factors. Results: One hundred eight patients (94% ASA 2 or 3) were reviewed at mean 5.3 months (±1.5). None of the patients were lost to follow-up. At revision, 19 patients had died (17.6%). The mean Parker score declined 1.4 points. All fractures healed at mean 10.4 weeks (±0.6). Six complications were noted: three operative site infections, three head slidings, one intraacetabular protrusion. No statistically significant could be identified. Nevertheless, the three cases with femoral head sliding occurred on fractures that were unstable (type 31-A2) which had a malpositioned blade. Discussion: There appears to be a consensus on the treatment of proximal fractures of the femur: screw-plate fixation for stable fractures, centromedullary nailing for the others. Arthroplasty is a second-line solution. There are few publications on the new spiral blade of the PFN-A. ®. This method spares bone stock and allows compaction of the cancellous bone, particularly adapted for osteoporotic bone: the efficacy is comparable with reference techniques with lower rates of sliding (2.%) and acetabular protrusion (< 1%)

Introduction: To quantify the magnitude and incidence of haemodynamic changes that occurs during the fixation of extracapsular proximal femoral fractures when using either intra-medullary or extra-medullary fixation device. Methods: A prospective group of 31 patients with extra-capsular proximal femoral fractures were randomised to either fixation using an extra-medullary compression hip screw or an intra-medullary hip screw. All patients received a general anaesthetic adhering to a standardised anaesthetic protocol including invasive blood pressure monitoring and arterial blood gas sampling. Trans-oesophageal Doppler probe and monitor was used to record pre-operative hypovolaemia and peri-operative changes in cardiac output, stroke volume and corrected flow time (FTc – a reflection of left ventricular end diastolic pressure) during placement of implants. Results: 77% of patients were hypovolaemic preoperatively, which was corrected with an average of 439 mls of colloid replacement fluid. Application of the extra-medullary CHS produced no change in haemodynamic function. However on insertion of the IMHS we found a statistically significant reduction in stroke volume, cardiac output and FTc without changes in pulse rate or mean arterial pressure. The changes were transient with normal cardiac function returning by 5 mins post operatively. Conclusion: The transient fall in cardiac function during insertion of the intramedullary hip screw may be caused by fat embolism entering the venous circulation. As these changes are not detected with standard non-invasive monitoring we would recommend that intramedullary devices be used with caution in elderly patients who tend to have poor physiological reserve

Background: A radiological audit of the local use of the Dynamic Hip Screw in extracapsular proximal femur fractures. Study aim: to identify cases of mechanical failure and revision, to determine predictors of fixation failure. Methods: A retrospective radiological review of 567 consecutive cases at Western Australian tertiary hospitals over a 3 year period (2002 – 2004) using the Picture Archive Computer System (PACS). Results: Female: male ratio was 2.79: 1. Evan’s classification: 418 fractures stable (73.7%), 149 unstable (26.3%). Failure of fixation occurred in 14 cases (2.5%); ten due to hip screw cut out (1.8%) and four due to plate pull off (0.8%). All cases of cut out had a significantly higher mean tip apex distance (TAD) (31 vs 20mm, P < 0.001) and an unstable fracture configuration; 8 of 10 had a poor reduction. Bivariate logistical regression revealed TAD of 25mm or more to be most predictive of cut out; followed by mean TAD, superior anterior and inferior posterior screw placement, unstable fracture configuration and poor reduction. Unassociated factors included gender, age, American Society of Anesthesiologists’ score, plate angle and length, operation time and surgeon level. A three-variable model found TAD of 25mm or more and unstable fracture configuration to be predictive, but not poor reduction. Cases with a TAD of 25mm or more with unstable fracture configuration and a poor reduction had a 21.6% chance of cut out (8 of 29). Conclusions: This is the first multifactorial multivariate analysis of a single implant sliding hip screw series. Compared with the literature, the rate of failure is low. Possible reasons include appropriate choice of implant for fracture type, improved performance with use of a single model of implant, and low exclusion rates due to the use of PACS

Introduction: Previous studies have demonstrated the value of the tip-apex distance (TAD) and the location of the screw in the femoral head in predicting cut-out. Similarly surgeons’ volume has been shown to affect mortality and morbidity in various surgical specialties, including in trauma and orthopaedics. Aim: To determine whether re-operation due to cut out at six month can be predicted using TAD, location of the screw and fracture type; and whether the experience of the surgeon is important. Methods: Logistic regression was used to analyse data collected retrospectively from 241 patients with extracapsular fractures (Jensen’s modification of Evans’ classification: Class I – 90, Class II – 93 and Class III – 58), treated with a dynamic hip screw, classic hip screw or intramedullary hip screw from April 2005 to October 2007. Results: There were 7 cut outs (2.5%) requiring re-operation within 6 months – 1 in the consultant group and 6 in the trainee group,. The model used was statistically significant (X2=23.6 [13df], p< 0.05). The tip-apex distance was a strong predictor (p< 0.05) of cut-out requiring re-operation at six months. The odds of the patient requiring re-operation due to cut out increases by a factor of 1.2 for each millimetre increase in the TAD. Location of the hip screw and fracture type were however not significant predictors. The first surgeon was a consultant in 54 cases and trainee in 187 cases. There was no statistically significant difference in re-operation rate due to cut out between patients operated on by consultants compared to trainees. Conclusion: The TAD is a strong predictor of cut out requiring re-operation at 6 months. No difference was found in our series in re-operation rate due to cut out among cases performed by consultants compared to trainees

Background: The most commonly used implant for the internal fixation of an extracapsular proximal femoral fracture is a sliding hip screw (SHS). More recently short intramedullary nails (IMN) have been advocated as an alternative, particularly for unstable fractures due to possible biomechanical advantages. The purpose of this meta-analysis was to compare, on the basis of evidence from randomised controlled trials, the fixation outcome with these two types of implant in stable and unstable fractures. Method: All randomised controlled studies comparing intramedullary nails with a SHS were considered for inclusion. Studies were identified using the search strategy of the Cochrane Collaboration, with no restriction on languages or source. Two authors independently extracted the data, and assessed trial methodology. Results: 24 randomised trials involving 3202 patients with 3279 fractures were included in the analysis. Pooled results gave no statistically significant difference in the cut-out rate between the IMN or SHS 41/1556 and 37/1626 (Relative risk 1.19; 95% confidence interval 0.78 to 1.82). There was an increased total failure rate (103/1495 and 58/1565, Relative risk 1.83; 95% confidence interval 1.35 to 2.50) and re-operation rate (57/1357 and 35/1415, Relative risk 1.63; 95% confidence interval 1.11 to 2.40) with the IMN compared the SHS when all fractures were considered. Fracture healing complications were much less frequent for stable fractures. No evidence for a reduced failure rate for IMN’s in unstable fractures patterns could be found. Conclusions: The results from studies to date indicate an increased fixation failure rate for trochanteric fractures fixed with an intramedullary nail, and show no benefit to the use of a nail in unstable fractures. Therefore the use of intramedullary nails for trochanteric fractures cannot be recommended

Fundaments: The surgical management of proximal femoral extra-capsular fractures in the elderly remains controversial. Bone quality and purchase of the cephalic screw are the main limitations of the currently available therapeutic options, dynamic hip screws-blade and proximal femoral nailing systems being the standard fixation Methods: which however report a revision rate of 7% due to mechanical failures. Main complications include implant-related fractures and cut out of the head-neck device with subsequent penetration into the acetabulum. The new PFNATM helical blade appears to improve the stability of the whole construct by providing better compaction of the cephalic cancellous bone around the blade.

Hypothesis, Type of Study: We conducted a retrospective radiographic-clinical study of a series of PFNATM osteosyntheses. Assessment of the mid-term results was based on the hypothesis that the PFNATM would reduce the occurrence of secondary deviations.

Materials and Methods: Between 2006 and 2008, 108 osteosyntheses were performed. Only traumatic fractures were included in this study. Parker’s quality of life scoring system (0 to 9) and Harris hip score (0 to 100) were used for functional evaluation. The PFNA blade position was assessed using intraoperative radiographs while a postoperative radiographic control was performed during follow-up to evaluate the occurrence of complications.

Results: 98 patients (98 hips) were reviewed at a mean follow-up of 5.3 months +/− 1.5. At last follow-up, the mean Parker score had decreased by 2.3 points and the Harris hip score by 24 points. All fractures united at an average time of 10.4 weeks (+/− 2.1). Six complications were reported (6.1%). They included 3 infections of the operative site and 3 cut-out of the femoral head. Three patients required reoperation for removal of the helical blade (3%): Two for significant migration and one for intra-acetabular penetration.

No statistically significant risk factors could be observed. However, the three cut-out of the femoral head occurred in unstable fractures (type 31-A.2 and 31-A.3 according to the AO classification) with mispositioning of the helical blade.

Discussion: Extra-capsular proximal femoral fractures are common in the elderly population but there is currently no ideal implant available. Unstable fractures as well as mispositioning of the head/neck device are considered risk factors for secondary varus deviation and external rotation. The new PFNATM helical blade has been rarely studied. It appears as a reliable osteosynthesis option since it reports encouraging results at a mean follow-up of 6 months. However, our results do not give evidence of the superiority of the helical blade over the neck screw.

Aims. Our rural orthopaedic service has undergone service restructure during the COVID-19 pandemic in order to sustain hip fracture care. All adult trauma care has been centralised to the Royal Shrewsbury Hospital for assessment and medical input, before transferring those requiring operative intervention to the Robert Jones and Agnes Hunt Orthopaedic Hospital. We aim to review the impact of COVID-19 on hip fracture workload and service changes upon management of hip fractures. Methods. We reviewed our prospectively maintained trust database and National Hip Fracture Database records for the months of March and April between the years 2016 and 2020. Our assessment included fracture pattern (intrascapular vs extracapsular hip fracture), treatment intervention, length of stay and mortality. Results. We treated 288 patients during March and April between 2016 and 2020, with a breakdown of 55, 58, 53, 68, and 54 from 2016 to 2020 respectively. Fracture pattern distribution in the pre-COVID-19 years of 2016 to 2019 was 58% intracapsular and 42% extracapsular. In 2020 (COVID-19 period) the fracture patterns were 65% intracapsular and 35% extracapsular. Our mean length of stay was 13.1 days (SD 8.2) between 2016 to 2019, and 5.0 days (6.3) days in 2020 (p < 0.001). Between 2016 and 2019 we had three deaths in hip fracture patients, and one death in 2020. Hemiarthroplasty and dynamic hip screw fixation have been the mainstay of operative intervention across the five years and this has continued in the COVID-19 period. We have experienced a rise in conservatively managed patients; ten in 2020 compared to 14 over the previous four years. Conclusion. There has not been a reduction in the number of hip fractures during COVID-19 period compared to the same time period over previous years. In our experience, there has been an increase in conservative treatment and decreased length of stay during the COVID -19 period. Cite this article: Bone Joint Open 2020;1-8:500–507

Aims. Using the Australian and New Zealand Hip Fracture Registry (ANZHFR) data, this study aimed to identify patient, fracture, and management factors associated with survival, mobility and residential status at 120 days. This will allow future interventions to target modifiable risk factors to improve the overall care of patients with hip fractures. Methods. All NZ patients from 2018 – 2020 were included. Baseline demographics, management factors, and outcomes were recorded. Key outcomes were change in walking status, residential status and survival at 120 days. Univariate analysis was performed to compare differences in demographics, surgical and management factors for the key variables. Multivariate analysis was conducted to identify factors independently associated with outcomes. Results. Data from 9432 patients were analysed. The average age was 82.8 years (SD 9.8). 70.3% were females. 39.5% of patients were cognitively impaired on admission, 71.4% were from their own residence. At 120 days post injury, 10.9% (1029) had died 1029 (10.9%), 15.3% (1034) had a decrease in their residential status, 44.9% (2966) had a reduction in walking ability. On multivariate analysis; older age (RR1.1/yr, p<0.001), male sex (RR1.7, P<0.001), cognitive impairment (RR2.2, p<0.001) and ASA>3 (RR3.7, p=0.015) were risk factors for death. Similarly, increasing age (RR1.1 per year, p<0.001), cognitive impairment (RR1.2, p=0.04) and ASA>3 (RR2.9, p=0.047) were significant risk factors for worsening residential status. Decreasing mobility was associated with extracapsular fractures (RR1.4, p=0.01). After adjustment for demographics, ASA and fracture type, performing total hip arthroplasty was preventative for both worsening residential status (RR0.23, p<0.001) and decreasing walking ability (RR 0.21, p<0.001). There was no significant survival, functional or revision differences for other fixation types. Conclusion. There is a significant decline in walking ability post hip fracture which may be a key contributor to long-term morbidity. The benefits of THA in preserving mobility and independence should be further investigated. Additional discharge planning and multi-disciplinary team input are likely required for high-risk patients of older age, with cognitive impairment and extracapsular fractures

Increasing incidence of osteoporosis, obesity and an aging population have led to an increase in low energy hip fractures in the elderly. Perceived lower blood loss and lower surgical time, media coverage of minimal invasive surgery and patient expectations unsurprisingly have led to a trend towards intramedullary devices for fixation of extracapsular hip fractures. This is contrary to the Cochrane review of random controlled trials of intramedullary vs extramedullary implants which continues recommends the use of a sliding hip screw (SHS) over other devices. Furthermore, despite published literature of minimally invasive surgery (MIS) of SHS citing benefits such as reduced soft tissue trauma, smaller scar, faster recovery, reduced blood loss, reduced analgesia needs; the uptake of these approaches has been poor. We describe a novel technique one which remains minimally invasive, that not only has a simple learning curve but easily reproducible results. All patients who underwent MIS SHS fixation of extracapsular fractures were included in this study. Technique is shown in Figure 1. We collated data on all intertrochanteric hip fractures that were treated by a single surgeon series during period Jan 2014 to July 2015. Data was collected from electronic patient records and radiographs from Picture Archiving and Communication System (PACS). Surgical time, fluoroscopy time, blood loss, surgical incision length, post-operative transfusion, Tip Apex Distance (TAD) were analyzed. There were 10 patients in this study. All fractures were Orthopaedic Trauma Association (OTA) type A1 or A2. Median surgical time was 36 minutes (25–54). Mean fluoroscopy time was similar to standard incision sliding hip screw fixation. Blood loss estimation with MIS SHS can be undertaken safely and expeditiously for extracapsular hip fractures

Abstract. Introduction. Several studies have shown that patients over 65 years have a higher mortality with covid. Combine with inherently increased morbidity and mortality in neck of femur (NoFF) fractures, it is logical to think that this subset would be most at risk. Aims. Investigate whether there is actual increase in direct mortality from Covid infection in NoFF patients, also investigate other contributing factors to mortality with covid positivity and compare the findings with current available literature. Methods. 1-year cross sectional, retrospective study from 1st March 2020 at two DGHs, one in Wales and one in England. Surgically treated NoFF patients with isolated intra/extracapsular fracture included. Mortality analysis done by creating a matched comparison group for each risk factor and combinations known to confer highest mortality. Chi square test for independence used to compare COVID status with 1 year mortality. Results. 610 patients, 62 patients had COVID-19RTPCR+ive test during hospital stay/in the community. 21(34%) deaths in COVID positive and 95 (17.33%) deaths in COVID negative patients. There was no mortality in ASA 1 or 2 patients. Analysis of asa matching with 10-year age ranges from 65years revealed a nearly double mortality rate in covid+ group as opposed to covid negative for both ASA 3 and 4 groups. Parameters such as preinjury mobility, residential status, AMTS score, time to surgery, did not seem to play a significant role in mortality. Conclusion. First of its kind study with a large subset of patients and unique parameters to identify causes leading to mortality in the vulnerable population of NoFF. Higher morality in Covid positive NoFF patients, but increase may not be as significant as identified by most current studies in the literature and still within the confines of NHFD stats(2019). Declaration of Interest. (b) declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported:I declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project

Extracapsular Hip Fractures (EHF's) are a significant health burden on healthcare services. Optimal treatment is controversial with conflicting evidence being reported. Currently treatment is undertaken with Intramedullary Nail (IMN) or Dynamic Hip Screw (DHS) constructs with a recent increase in IMN use (1). This study aims to conduct a systematic review of Randomised Control Trials published between 2020 and 2023 with particular focus on patient demographics and holistic patient outcomes. Using a unified search-protocol, RCT's published between 2020 and 2023 were collected from CENTRAL, PubMed, MEDLINE and EMBASE. Rayyan software screened duplicates. Using the CASP and Cochrane Risk of Bias Tool papers were critically examined twice, and Blood Loss, Infection and Mobility described the patient journey. Patient demographics were recorded and were contrasted with geographically diverse cohort studies to compare population differences. Parametric tests were used to determine significance levels between population demographics, namely Age and Sex. Eleven papers were included, representing 908 patients (436 Male). The mean age for patients was 64.39. There was considerable risk of bias in 7/11 studies owing to the randomization process and the recording of data. Four Cohort studies were selected for comparison representing 14314 patients. Mean age was significantly different between Cohort Studies and RCT's (Independent T-Test, df 13, t=7.8, p = <0.001, mean difference = 19.251, 95% CI = 13.888, 24.613). This was also true for sex ratios included in the studies (df 13, t = -2.268, p = 0.024, Mean Difference = -0.4884, 95% CI = -0.9702, -0.0066). To conclude, RCT's published in the post COVID-19 era are not representative of patient demographics. This has the potential to provide inaccurate information for implant selection. Additionally further research must be conducted in how to better improve RCT patient inclusion so as to be more representative of patients whilst balancing the risks of operations

There is no optimal therapy to stop or cure chondral degeneration in osteoarthritis (OA). Beside cartilage, subchondral bone is involved. The often sclerotic bone is mechanically less solid which in turn influences negatively chondral quality. Microfracturing as therapeutic technique aims to enhance bone quality but is applied only in smaller cartilage lesions. The osteoproliferative properties of Magnesium (Mg) have been shown repeatedly. 1-3. The present study examined the influence of micro-scaled Mg cylinders compared to sole drilling in an OA model. Ten New Zealand White rabbits underwent anterior crucial ligament transection. During 12 weeks after surgery, the animals developed OA as previously described. 4. In a second surgery, half of the animals received 20 drill holes (ø 0.5mm) and the other half received 20 drill holes, which were additionally filled with one Mg cylinder each. Extracapsular plication was performed in all animals. During the follow-up of 8 weeks three µ-computed tomographic (µCT) scans were performed: immediately after surgery and after four and eight weeks. Changes of bone volume, trabecular thickness and bone density were calculated and compared. µCT evaluation showed an increase in bone volume and trabecular thickness in both groups. This increase was significantly higher in rabbits which received Mg cylinders showing thrice as high values for both parameters (bone volume: Mg group +44.5%, drilling group +15.1%, p≤0.025; trabecular thickness: Mg group +53.2%, drilling group +16.9%, p≤0.025). Also bone density increased in both groups, but on a distinctly lower level and with no significant difference. Although profound higher bone volume was found after implantation of Mg cylinders, µCT showed similar levels of bone density indicating adequate bone quality in this OA model. Macroscopic and histological evaluation of cartilage condition have to reveal possible impact on OA progression. Additionally, current examination implement different alloys and influence on lameness

Introduction. Neck of femur (NoF) fractures have an inherent 6.5% 30-day mortality as per National hip fracture database(2019). Several studies have demonstrated a higher mortality rate in covid positive NoFs but have been unable to demonstrate whether there are risk factors that contribute to the risk of mortality in this patient group or whether COVID is solely responsible for the higher mortality. Aims. To assess risk factors that are concurrently present in a fracture NoF cohort that may contribute to higher mortality in COVID positive patients. Methods. A cross sectional, retrospective study was performed for a period of 1 year starting from 1st March 2020. All surgically treated neck of femur fracture patients having an isolated intra/extracapsular fracture were included in the study. Data fields recorded- patient demographics, date and time of admission, ward discharge, surgery, mode of surgery (fixation/arthroplasty), prehospital AMTS score, residential status and mobility, ASA grade as per anaesthetist's records, date of death (if deceased), cause of death (as per death certificate/ postmortem / coroner's report). Analysis of mortality was carried out by creating a matched comparison group for each risk factor as well as some combinations. Results. 344 patients were surgically treated for a neck of femur fracture in our DGH during the period of 1st March 2020 to 28th February 2021. 46 patients did not receive a COVID swab (reasons unknown) and were excluded from the study. 35 patients had a COVID-19 RT PCR positive test during their hospital stay and 264 patients remained negative. There were 12 deaths in COVID positive patients (34%) and 53 deaths in COVID negative patients (20%) within the time frame of the study. For each risk factor matched group COVID was seen to confer higher mortality in general. There was no mortality in ASA 1 or 2 patients. Mortality rates in matched groups for age and ASA revealed 23.8% mortality in COVID positive as opposed to 17.3% in COVID negative for ASA 3 and 33.3% mortality in COVID positive vs. 28% in ASA 4. 11 out of the 12 COVID positive patients who died had an AMTS score >6. No correlation was seen between COVID positive deaths and preinjury residential status, type of fracture or surgery offered, or preinjury mobility. The average length of hospital stay was much higher for COVID positive patients (19.5days) as compared to 9.5 days for COVID negative patients. Conclusion. Matched group analysis show that there is a 37.5% increase in COVID positive neck of femur fracture mortality in ASA 3 patients, the same number falls to 17.8% for ASA 4 patients. These figures are much lower compared to other studies in the UK. There is a need to understand the real cause of death in this subset and to improve death certification so that we can differentiate between patients whose mortality is ‘due to’ or ‘With’ COVID

Background. Isolated fracture of the greater trochanter is an uncommon presentation of hip fracture. Traditional teaching has been to manage these injuries nonoperatively, but modern imaging techniques have made it possible to detect occult intertrochanteric extension of the fracture in up to 90% of cases. This study aims to review the investigation and management of greater trochanter fractures in a single major trauma centre. Methods. A retrospective review was completed of patients admitted with greater trochanter fractures. These were matched to cases with 2-part extracapsular fractures. Initial management and clinical outcome was established using electronic notes and radiographs. Mortality and length of stay was calculated for both groups. Results. 85 isolated greater trochanter fractures in 84 patients were identified from 2006–2017. 81/85 patients were treated non-operatively. 78 were mobilised full weight bearing. None required readmission or operation due to fracture displacement. 58 of these patients had cross-sectional imaging with MRI or CT and 15 of those scanned had intertrochanteric extension of the fracture. In the same time period, 998 2-part extra-capsular fractures were treated, using a sliding hip screw. Length of stay was shorter in patients with greater trochanter fractures than 2-part extracapsular fractures (median 7 days vs 14 days, P<0.0001). 30-day mortality was 11.9%, with no significant difference to patients with 2-part extracapsular fractures. Discussion. Cross sectional imaging rarely changed the treatment protocol for isolated greater trochanter fractures. The outcome following non-operative treatment is good even in the presence of occult fractures identified on CT or MRI. We advocate a treatment protocol that encourages early mobilisation and repeat plain radiographs if patients fail to progress. This will reduce unnecessary morbidity from fixation of stable occult fractures