Background. The National Institute of Clinical Excellence (NICE) published clinical guidelines in 2006 defining urgent referral criteria for soft tissue sarcoma to help improve the diagnostic accuracy and overall outcome. Despite these guidelines
Aims. Delays to diagnosis and management of soft tissue sarcomas are preventable but still occur. The introduction of a referral proforma to the Thames Valley Cancer Network in 2005 and National guidelines in 2006 aimed to decrease the incidence of partially and inadequately managed soft tissue sarcomas. This study aims to assess referrals for partially or inadequately managed soft tissue sarcomas and their subsequent management. Methods. A prospective analysis of all patients referred to the Oxford Sarcoma Service following
Background. This clinical study aims to establish the rate of operative
Lisfranc injuries account for 0.2% of all fractures and have been linked to poorer functional outcomes, in particular resulting in post-traumatic arthritis, midfoot collapse and chronic pain. This study assesses the longitudinal functional outcomes in patients with low and high energy Lisfranc injuries treated both operatively and non-operatively. Patients above 16 years with Lisfranc injuries from January 2008 and December 2017 were identified through the Victorian Orthopaedic Trauma Outcomes (VOTOR) registry. Follow-up performed at 6, 12 and 24 months through telephone interviews with response rate of 86.1%, 84.2% and 76.2% respectively. Longitudinal functional outcome data using Global Outcome Assessment, EQ-5D-5L, numerical pain scale, Short-Form 12, the WHO Disability Assessment Schedule and return to work status were collected. Univariate analysis was performed and variables showing a significant difference between groups (p < 0.25) were analysed with multivariable mixed effects regression model. 745 patients included in this retrospective cohort study. At 24 months, both the operative and non-operative groups demonstrated similar functional outcomes trending towards an improvement. Mixed effect regression models for the EQ items for mobility (OR 1.80, CI 0.91 – 3.57), self-care (OR 1.95, 95% CI 1.09-3.49), usual activities (OR 1.10, 95% CI 0.99-1.03), pain (OR 1.07, 95% CI 0.61-1.89), anxiety (OR 1.29, 95% CI 0.72-2.34) and pain scale (OR 1.07, 95% CI 0.51 – 2.22) and return to work (OR 1.28, 95% CI 0.56-2.91) between groups were very similar and not statistically significantly different. We concluded that there was no statistically significant difference between operative and non-operative patients with low and high energy Lisfranc injuries. Current clinical practices in Lisfranc injury management are appropriate and not
Timely and competent treatment of paediatric fractures is paramount to a healthy future working population. Anecdotal evidence suggests that children travel greater distances to obtain care compared to adults causing economic and geographic inequities. This study aims to qualify the informal regionalization of children's fracture care in Ontario. The results could inform future policy on resource distribution and planning of the provincial health care system. A retrospective cohort study was conducted examining two of the most common paediatric orthopaedic traumatic injuries, femoral shaft and supracondylar humerus fractures (SCH), in parallel over the last 10 years (2010-2020) using multiple linked administrative databases housed at the Institute for Clinical Evaluative Sciences (ICES) in Toronto, Ontario. We compared the distance travelled by these pediatric cohorts to clinically equivalent adult fracture patterns (distal radius fracture (DR) and femoral shaft fracture). Patient cohorts were identified based on treatment codes and distances were calculated from a centroid of patient home forward sortation area to hospital location. Demographics, hospital type, and closest hospital to patient were also recorded. For common upper extremity fracture care, 84% of children underwent surgery at specialized centers which required significant travel (44km). Conversely, 67% of adults were treated locally, travelling a mean of 23km. Similarly, two-thirds of adult femoral shaft fractures were treated locally (mean travel distance of 30km) while most children (84%) with femoral shaft fractures travelled an average of 63km to specialized centers. Children who live in rural areas travel on average 51km more than their adult rural-residing counterparts for all fracture care. Four institutions provide over 75% of the fracture care for children, whereas 22 institutions distribute the same case volume in adults.?. Adult fracture care naturally self-organizes with proportionate distribution without policy-directed systemization. There is an unplanned concentration of pediatric fracture care to specialized centers in Ontario placing undue burden on pediatric patients and
Myxofibrosarcoma (MFS) is the second most common subtype of soft tissue sarcoma (STS) and is associated with a high rate of local recurrence after resection. These tumours frequently present with peri-lesional edema, termed “tumour tails” on staging MRI scans [1]. Tumour tails(TT) may contain satellite neoplastic cells or can represent benign reactive edema. There are no clear radiological features to distinguish malignant from reactive peri-lesional edema which limits accurate surgical planning, resulting in either high rates of
Introduction. Primary soft tissue sarcomas of the extremities are uncommon. Many such lesions will present to specialists in other clinics such as specialist Hand or Foot and Ankle clinics. Many are of a small size at presentation and may appear to be alternate, more common pathology. Methods. We collected data from all those patients with acral soft tissues sarcomas and referred to the Oxford Sarcoma Service, Nuffield Orthopaedic Centre, Oxford over a thirteen year period from 1997 – 2010. Data were collected regarding the primary suspected diagnosis, the final diagnosis, the referral route and whether patients had undergone previous
Summary. A rotational limit for screw insertion may improve screw purchase and plate compression by reducing stripping, as compared to a torque based limit. Introduction. Over-tightening screws results in
Background. Use of a robotic tool to perform surgery introduces a risk of unexpected soft tissue damage due to the uncommon tactile feedback for the surgeon. Early experience with robotics in total hip and knee replacement surgery reported having to abort the procedure in 18–34 percent of cases due to inability to complete preoperative planning, hardware and soft tissue issues, registration issues, as well as concerns over actual and potential soft tissue damage. These can result in significant morbidity to the patient, negating all the desired advantages of precision and reproducibility with robotic assisted surgery. The risk of soft tissue damage can be mitigated by haptic software prohibiting the cutting tip from striking vital soft tissues and by the surgeon making sure there is a clear workspace path for the cutting tool. This robotic total knee system with a semi-active haptic guided technique was approved by the FDA on 8/5/2015 and commercialized in August of 2016. Two year clinical results have not been reported to date. Objective. To review an initial and consecutive series of robotic total knee arthroplasties for safety in regard to avoidance of known or delayed soft tissue injuries and the necessity to abort the using the robot to complete the procedure. Report the clinical outcomes with robotic total knee replacement at or beyond two years to demonstrate no delayed effect on expected outcome. Methods. The initial consecutive series of 65 Triathlon. TM. total knee replacements using a semi-active haptic guided system that were performed after commercialization that would be eligible for two year follow-up were reviewed. Pre-operative planning utilizing CT determined the implant placement and boundaries and thus the limit of excursion from any part of the end effector saw tip. Self-retaining retractors were also utilized. Operative reports, 2, 6, and 12 week, and yearly follow-up visit reports were reviewed for any evidence of
Introduction: The curing of polymethylmethacrylate cement is an exothermic reaction, with temperatures reaching 80oC. Thus contact with cement can result in thermal injury. During orthopaedic procedures bone cement may be
Two stage exchange has been the gold standard in North America for the treatment of infected knee replacements. The choice of static vs. articulated spacers has been debated for a number of years. At our institution our choice of spacer for 2 stage exchanges is an articulated spacer. This allows motion between stages which facilitates recovery, and makes the second stage technically easier. In a study from our institution we followed 115 infected TKAs treated with the PROSTALAC articulated spacer for 5–9 years. Success for eradication of infection was 88%. With a repeat 2 stage, overall infection control was 98%. In addition, we compared functional outcomes to a group of aseptic knee revisions and found no difference in functional outcomes with standard quality of life outcome scores. While the articulated spacer was our treatment of choice in 2 stage exchange around 2012, the company that manufactured the PROSTALAC knee components ceased to manufacture them. At that time, based on the work of 2 previous studies (Hofmann, Lee), we continued to use articulated spacers. However, this was now the so-called Hofmann technique with a new standard femoral component with an all polyethylene tibia. The only difference from a standard knee revision was no stems and the utilization of high dose antibiotics. We also followed the principles from Europe of one stage exchange, such as wide debridement and soaking in dilute betadine for 15 minutes. More recently as of Sept 2015 we have used an all polyethylene tibia with a keel. The hope being that this will give a more stable tibia than previous and perhaps make a second stage unnecessary. Our first case was September 2015. The intention was not to do a second stage if the infection was eradicated and the patient had good pain relief and function. To date we have implanted 28 of these and in 80% of cases we have not had to do a second stage revision. Further study will reveal where this
Introduction. Patient Specific Guides (PSGs) are used to increase the accuracy of arthroplasty. PSGs achieve this by incorporating geometry that fits in one unique position and orientation on a patient's bone. Sufficient docking rigidity ensures PSGs do not shift before being fixed by pins. Despite the importance of PSG docking rigidity, minimal research has been conducted on this issue. This study aims to determine whether commercially available PSGs, in their equilibrium position, provide sufficient stability for reliable surgical use. Materials and Methods. A commercially available PSG (Glenoid PSG, BLUEPRINT™, Wright Medical) was analyzed and tested in this study; the mechanical performance of this guide was assessed using a custom testing apparatus mounted to a universal testing machine (UTM) (MTI-10k, Materials Testing Inc), assembled with a high-precision load cell (MiniDyn Type 9256C, Kistler). The apparatus accepts an additively manufactured glenoid surrogate and was designed to transform vertical crosshead forces from the UTM into PSG-applied forces transverse to the glenoid plane along anterior-posterior and superior-inferior axes and PSG-applied torques about lateral, anterior, and superior axes. Three trials were recorded for each force and torque application. Prior to each test, the glenoid surrogate and PSG were articulated together with a constant 27N compressive force — equivalent to the normal force exerted by a surgeon using the guide — applied using springs. Forces were recorded when the guide was displaced 2mm by transverse loads or 5° by torque application; if the guide visibly dislodged from the glenoid surrogate before either criterion was met, force was recorded at the time of dislodgement. If no PSG movement occurred, testing ceased at 75N or 1.19N⋅m, depending on the test type. Results. The lowest and highest torques to displace the PSG by 5° were around the lateral (−0.08±0.02 N⋅m) and superior axes (0.87±0.23 N⋅m), respectively. The lowest and highest forces to displace the PSG by 2mm were along the inferior (31.77± 6.30N) and posterior axes (64.80±0.79N), respectively. Although it yielded at a higher torque than about the lateral axis, CCW rotation about the posterior axis produced the earliest PSG dislodgement at 3.76° while the PSG dislodged after only 1.05mm in the anterior direction. Discussion. The above results demonstrate that the tested PSG design produces similar docking rigidity for all tested rotations except rotations about the lateral axis, which provided 4 times less stability than the next lowest result. This indicates that the PSG may not provide sufficient resistance in this direction to prevent
We introduce a new technique called the “Posterior Cruciate Referencing Technique” (PCRT), a specific combination of surgical technique, devices and instrumentation. Careful anatomic preservation of the posterior cruciate ligament (PCL) based upon a specific reference point off the tibia allows for use of sloped tibial components to achieve consistent functional behavior of the PCL. We discuss the preclinical design and development leading to availability of this device, and subsequent early clinical experience with this approach. Posterior cruciate ligament (PCL) retention in total knee arthroplasty (CR-TKA) has been a feature of certain styles of TKA since the inception of predictable TKA in the early 1970s. It has been adapted and promoted as advantageous for a number of real and theoretical benefits. In reality, however, PCL retention has proven inconsistent when applied across a broad range of surgical environments. A number of adaptations in surgical technique, device modification and instrumentation have been developed to try to improve the predictability of the surgical intervention and subsequent postoperative performance. It is our belief that currently recommended surgical techniques can lead to inconsistencies in surgical judgment and consequently performance of CR devices because they
The extended proximal femoral osteotomy has been used primarily in conjunction with cementless fixation, but has been described for use with cemented stems as well. The extended proximal femoral osteotomy is indicated for the removal of well-fixed cemented and cementless implants, as well as removal of cement in patients with a loose femoral component in a well-fixed cement mantle. Although the osteotomy is not required for many femoral revisions, it is an absolute indication in patients with femoral component loosening and subsequent varus remodeling of the proximal femur. The osteotomy diminishes the risk of an
Background. Use of a robotic tool to perform surgery introduces a risk of unexpected soft tissue damage due to the lack of tactile feedback for the surgeon. Early experience with robotics in total hip and knee replacement surgery reported having to abort the procedure in 18–34 percent of cases due to inability to complete preoperative planning, hardware and soft tissue issues, registration issues, as well as concerns over actual and potential soft tissue damage. These damages to the soft tissues resulted in significant morbidity to the patient, negating all the desired advantages of precision and reproducibility with robotic assisted surgery. The risk of soft tissue damage can be mitigated by haptic software prohibiting the cutting tip from striking vital soft tissues and by the surgeon making sure there is a clear workspace path for the cutting tool. This robotic total knee system with a semi-active haptic guided technique was approved by the FDA on 8/5/2015 and commercialized in August of 2016. One year clinical results have not been reported to date. Objective. To review an initial and consecutive series of robotic total knee arthroplasties for safety in regard to avoidance of known or delayed soft tissue injuries and the necessity to abort the robotic assisted procedure and resort to the use of conventional implantation. Report the clinical outcomes with robotic total knee replacement at or beyond one year to demonstrate satisfactory to excellent performance. Methods. The initial consecutive series of 100 robotic total knee replacements using a semi-active haptic guided system including 34 from the initial IDE series in 2014 and those performed after commercial approval beginning in 2016 were reviewed. Pre- operative planning utilizing CT determined the implant placement and boundaries and thus the limit of excursion from any part of the end effector saw tip. Self-retaining retractors were also utilized. Operative reports, 2, 6, and 12 week, and yearly follow-up visit reports were reviewed for any evidence of
It is unusual to require the use of a total knee implant with more constraint than a posterior-stabilised post in primary knee arthroplasty. The most common indication is a knee with a severe deformity, usually fixed valgus with an incompetent medial collateral ligament, and an inability to correctly balance the knee in both flexion and extension. The pre-operative deformity is usually greater than 15–20 degrees fixed valgus and may be associated with a severe flexion contracture. This is usually seen in an elderly female patient with advanced osteoarthritis. Those pre-operative diagnoses more likely to require a constrained design include advanced rheumatoid arthritis, true neuropathic joint, and the “Charcot-like” joint due to bone loss or crystalline arthritis. Rarely, patients with periarticular knee Paget's disease of bone may require more constraint following correction of a severe deformity through the knee joint. Beware those patients with a staple or screw at the medial epicondyle or those with severe heterotopic ossification at the medial joint line, as this may signify a serious prior injury to the medial collateral ligament. Finally, there is a possibility of
The extended proximal femoral osteotomy has been used primarily in conjunction with cementless fixation, but has been described for use with cemented stems as well. The extended proximal femoral osteotomy is indicated for the removal of well-fixed cemented and cementless implants, as well as removal of cement in patients with a loose femoral component in a well-fixed cement mantle. Although the osteotomy is not required for many femoral revisions, it is an absolute indication in patients with femoral component loosening and subsequent varus remodeling of the proximal femur. The osteotomy diminishes the risk of an
Introduction. Multimodal pain management strategies are now commonplace in perioperative management of total knee arthroplasty (TKA), although controversy remains regarding the role of adductor canal blocks (ACB) in this algorithm. Proposed benefits include theoretical decreased role of perioperative narcotic pain medication, improved function with physical therapy postoperatively, shorter duration of hospital stay and improved patient satisfaction. Those opposed cite increased cost and risk of complications including
Two stage exchange has been the gold standard in North America for the treatment of infected knee replacements. The choice of static versus articulated spacers has been debated for a number of years. At our institution our choice of spacer for two-stage exchanges is an articulated spacer. This allows motion between stages which facilitates recovery, and makes the second stage technically easier. In a study from our institution we followed 115 infected TKAs treated with the PROSTALAC articulated spacer for 5–9 years. Success for eradication of infection was 88%. With a repeat two stage overall infection control was 98%. In addition we compared functional outcomes to a group of aseptic knee revisions and found no difference in functional outcomes with standard quality of life outcome scores. While the articulated spacer was our treatment of choice in two-stage exchange around 2012 the company that manufactured the PROSTALAC knee components ceased to manufacture them. At that time based on the work of 2 previous studies (Hofmann, Lee), our institution continued to use articulated spacers. However, this was now the so-called Hofmann technique with a new standard femoral component with an all-polyethylene tibia. The only difference from a standard knee revision was no stems and the utilisation of high dose antibiotics. We also followed the principles from Europe of one-stage exchange, such as wide debridement and soaking in dilute betadine for 15 minutes. More recently, as of Sept 2015, we have used an all-polyethylene tibia with a keel. The hope being that this will give a more stable tibia than previous and perhaps make a second stage unnecessary. Our first case was September 2015. The intention was not to do a second stage if the infection was eradicated and the patient had good pain relief and function. To date we have implanted 12 of these and in all cases we have not had to do a second stage revision. Further study will reveal where this
Background. Aseptic loosening of cemented femoral stems results from migration of wear particles along the bone-cement interface, producing a foreign body reaction. After cement insertion, blood back pressure can disrupt the bone-cement interface, enabling this spread of wear particles. Our study investigates whether altering timing and speed of stem insertion can reduce this risk. Methods. We inserted mock “C-Stem” femoral components (De Puy-Synthes), using Smartset HV cement (De Puy-Synthes) into artificial femora, fitted with proximal and distal pressure transducers. Cement insertion began two, three or four minutes after mixing. Cement pressures were then allowed to settle for one minute and the stems were then inserted over durations of 25, 60 or 90 seconds. Results. Quicker insertion led to high peak pressures; however insertion over 90 seconds at 4 and 5 minutes achieved more sustained pressures above blood back pressure. Slower insertion particularly improved proximal pressurisation. Furthermore when the stem was inserted over 90 seconds at 5 minutes then the cement pressures remained high after full insertion of the stem. Conclusions. Commonly, femoral stems are inserted rapidly. Our study demonstrates that by inserting the femoral stem more slowly, cement pressure can be maintained above blood back pressure for longer. We believe that after slower stem insertion, the higher cement viscosity enables the surgeon to maintain cement pressure, via the stem, sufficient to resist blood back pressure without