Background and Purpose: Retrospective evaluation of short-term (8 weeks) and long-term (54 weeks) radiologic follow-up of vertebral wedge angle and anterior, center and posterior vertebral heights after Percutaneous VertebroPlasty (PVP) in type II Osteoporotic Vertebral Compression Fractures (OVCF). Methods: Between September 2002 and August 2007 47 PVP’s were performed in 25 consecutive patients (5 male, 20 female (age 70 ± 9,5 yrs) with OVCF’s type II (mean fracture age: 35.0 weeks (range: 10.0 – 136.7)). With pre-vertebroplasty conventional radiographs and MRI’s, post-vertebroplasty CT’s and conventional radiographs follow-up of the vertebral compression fractures were analyzed. Analysis of vertebral morphometrics with emphasis of the vertebral wedge angle and height of the vertebral body at the anterior, center and posterior border. Determining the loss and gain of height of the vertebra with OVCF pre- and post-PVP up to one year, using pre-PVP estimated heights. Results: A mean wedge angle reduction of 2.9° and anterior- and center heigth gain of 4.4% and 5.6% directly post-PVP, posterior height remained stable. The parameters at short- and long-term follow-up compared to the pre-PVP parameters showed no significant differences accept for anterior height. Conclusion: Besides alleviating the refractory back pain in patients a limited decrease in wedge angle and increase of anterior and center height is possible in type II OVCF. Although the long-term follow-up depicts a slight anterior height loss, the wedge angle and restored center height were stable

Introduction. Porous scaffolds for bone ingrowth have numerous applications, including correcting deformities in the foot and ankle. Various materials and shapes may be selected for bridging an osteotomy in a corrective procedure. This research explores the performance of commercially pure Titanium (CPTi) and Tantalum (Ta) porous scaffold materials for use in foot and ankle applications under simplified compression loading. Methods. Finite element analysis was performed to evaluate von Mises stress in 3 porous implant designs: 1) a CPTi foot and ankle implant (Fig 1) 2) a similar Ta implant (wedge angle = 5°) and 3) a similar Ta implant with an increased wedge angle of 20°. Properties were assigned per reported material and density specifications. Clinically relevant axial compressive load of 2.5X BW (2154 N) was applied through fixtures which conform to ASTM F2077–11. Compressive yield and fatigue strength was evaluated per ASTM F2077–11 to compare CPTi performance in design 1 to the Ta performance of design 3. Results. FEA results indicate peak stresses at fixture contact locations. Similar designs (CPTi design 1 and Ta design 2) resulted in similar von Mises stresses (Fig 1). Increasing the wedge angle (Ta design 3) increased stress by 15%. The static compressive yield strength of CPTi design 1 (20,560 N) was similar to the Ta design 3 (20,902 N), with yield manifesting as barreling and crushing of the components (Fig 2a). However, the fatigue strength of CPTi (6,000 N) was 40% lower than the Ta design 3 (9,500 N) (Fig 3). In both cases fracture initiated from regions of highest stress predicted in FEA. Fracture progression was not instantaneous and was characterized by an accumulation of damage (Fig 2b–c) leading to gross component fracture and loss of implant integrity. Discussion. FEA is a useful tool to determine stress variations and can be used to identify worst case within a material: in this case, a larger implant wedge angle leads to higher stresses. Additionally, FEA accurately predicted fracture initiation location. However, material selection plays a large role in porous implant performance: although FEA predicted higher stresses in a Ta component with a greater wedge angle than a similar sized CPTi component, static compressive strengths were nearly identical, and the Ta component had 58% higher fatigue strength. When selecting a material or geometry for an implant application, both FEA and static testing allow for rapid evaluation of designs. However, caution should be used in interpreting the results: the ultimate performance of an implant in-vivo will depend on its ability to maintain integrity over a long period of time, and should be characterized by dynamic testing

Study Design: Retrospective Series. Objectives: To analyse loss of correction of the anterior wedge angle and the components responsible for the recurrence of kyphosis after surgical stabilisation of dorsolumbar fractures, and to assess the return of functional capacity in these patients. Materials and Methods: Between January 1998 and March 2003, 34 patients had posterior stabilisation performed with the Universal Spine System (Synthes) for dorsolumbar fracture at a single level with no neurological deficit. There were 26 AO Type A fractures, 5 Type B fractures, and 3 Type C fractures. Serial standing lateral radiographs were taken from the immediate postoperative period to the most recent follow-up. The anterior wedge angle, the heights of the discs above and below the fractured vertebra, and the heights of the vertebral bodies above, at, and below the fractured level were measured. The height at each level was measured in three segments (anterior, middle and posterior). The values were normalised to avoid discrepancies while comparing radiographs. The difference in the height of each segment measured between the immediate postoperative period and the most recent follow-up were computed. Short Form 36 (SF-36) was used to assess the functional outcome in each. Results: The mean follow-up period was 23.6 months (9 to 48 months). The mean anterior wedge angle was 10.1 ± 7.2 degrees in the immediate postoperative period and 17.1 ± 10.9 degrees at latest follow-up (p< 0.001). The mean loss of correction was 7.0 ± 8.5 degrees (−11 to 24) and this showed a linear relationship to the preoperative anterior wedge angle. Furthermore there was a linear increase in the loss of correction of the angle as the follow-up period increased. The correlation between the corresponding difference in the height of each segment and the degree of loss of correction of the anterior wedge angle showed significant correlation to the decrease in the anterior segment height at the fractured vertebral body level (Pearson’s coefficient r=0.53 significant at 0.01 level, p=0.001). The mean physical function score from SF-36 was 56.3 and the mean bodily pain score was 49.7. There was no relationship to the angle of kyphosis at follow-up to the physical function score (r=0.12, p=0.50) and the bodily pain score (r=0.14, p=0.44). Conclusions: There is a progressive loss of correction (increasing kyphosis) after posterior stabilisation with instrumentation that roughly approximates the initial decrease in anterior height of the fractured vertebral body. The degree of loss of correction does not depend on the type of fracture. The loss of correction is related to the preoperative angle of kyphosis

Introduction. Osteoporotic vertebral fractures can cause severe vertebral wedging and kyphotic deformity. This study tested the hypothesis that kyphoplasty restores vertebral height, shape and mechanical function to a greater extent than vertebroplasty following severe wedge fractures. Methods. Pairs of thoracolumbar “motion segments” from seventeen cadavers (70–97 yrs) were compressed to failure in moderate flexion and then cyclically loaded to create severe wedge deformity. One of each pair underwent vertebroplasty and the other kyphoplasty. Specimens were then creep loaded at 1.0kN for 1 hour. At each stage of the experiment the following parameters were measured: vertebral height and wedge angle from radiographs, motion segment compressive stiffness, and stress distributions within the intervertebral discs. The latter indicated intra-discal pressure (IDP) and neural arch load-bearing (F. N. ). Results. Fracture and cyclic loading reduced anterior vertebral height by 34%, increased wedge angle from 5.0° to 11.4°, increased F. N. by 58% and reduced IDP and compressive stiffness by 96% and 44% respectively. Kyphoplasty restored anterior height to a greater extent than vertebroplasty (p<0.001), by 96% versus 59% immediately after augmentation, and by 79% versus 47% after subsequent creep loading. Wedge angle was also reduced to a greater extent following kyphoplasty than vertebroplasty (p<0.02) by 7.2° vs 4.2° after augmentation and 6.6° vs 4.0° after creep loading. IDP, F. N. and compressive stiffness were restored to a similar extent by both procedures. Conclusion. Kyphoplasty and vertebroplasty were equally effective in restoring mechanical function following severe wedge fractures, but kyphoplasty was better able to correct deformity by restoring vertebral height and reducing wedging. No conflicts of interest. Sources of funding: Funding was provided by a Royal College of Surgeons of England Research Fellowship and the Gloucestershire Arthritis Trust. Materials were provided by Medtronic and Depuy. This abstract has not been previously published in whole or substantial part nor has been presented previously at a national meeting

High tibial osteotomy (HTO) is a common surgical procedure for treatment of patients with varus mal-alignment. The success rate of the procedure is strongly dependent on the quality of the correction. Thus, an accurate pre-planning is essential to ensure that the precise amount of alignment is achieved postoperatively. The purpose of this study was to simulate the HTO in a patient with varus deformity in order to explore the interactions between the wedge angle, the mechanical axis, and the knee joint configuration. A finite element model of the knee joint of a patient with varus deformity was developed. The geometry was obtained using the whole limb CT scans the knee MR images. The bones were assumed as rigid bodies, the articular cartilage and the meniscus as elastic solids, and the ligaments as nonlinear springs. A 600N force was applied at the femoral head in the line of the mechanical axis and the resulting knee configuration was studied. The HTO was simulated assuming insertion of wedges with different angles beneath the tibial plate and applying the resulting alteration of the loading axis to the model. The results indicated that the actual change of the mechanical axes was always smaller than what predicted by a geometric pre-planning approach that does not consider the post-operative change of the knee joint configuration. It was suggested that subject-specific models are needed to simulate the HTO in patients before surgery and determine the appropriate wedge angle that locates the mechanical axis in the middle of the knee

Eight consecutive patients with significant malalignment of the lower limb were included in the study. Pre-operative CT scans of the affected limb and the normal contra-lateral side were obtained and 3D models of the patient's anatomy were created, using dedicated software. The healthy contralateral limb was mirrored and geometrically matched to the distal femur or proximal tibia of the healthy side. A virtual opening wedge correction of the affected bone was used to match the geometry of the healthy contralateral bone. Standard lower limb axes measurements confirmed correction of the alignment. Based on the virtual plan, surgical guides were designed to perform the planar osteotomy and achieve the planned wedge opening and hinge axis orientation. The osteotomy was fixed with locking plates and screws. Post-operative assessment included planar X-rays, CT-scan and full leg standing X-rays. One three-planar, three bi-planar and four single-plane osteotomies were performed. Maximum weightbearing mechanical femoro-tibial coronal malalignment varied between 7° varus and 14° valgus (mean 7.6°, SD 3.1). Corrective angles varied from 7°–15°(coronal), 0°–13°(sagittal) and 0°–23°(horizontal). The maximum deviation between the planned pre-operative wedge angle and the executed post-operative wedge angle was 1° in the coronal, sagittal and horizontal plane. The desired mechanical femorotibial axis on full-leg standing X-rays was achieved in 6 patients. Two patients were undercorrected by 1° and 2° respectively. Conclusion. 3D planning and guided correction of multi-planar deformity of femur or tibia is a feasible and accurate novel technique

Osteotomies around the knee are traditionally templated on 2D plain X-rays. Results are often inaccurate and inconsistent and multiplanar osteotomies are hard to perform. The aim of this study is to evaluate the feasibility and accuracy of virtual three-dimensional CT-based planning and correct execution of osteotomies around the knee with the aid of patient specific surgical guides and locking plates. Eight consecutive patients with significant malalignment of the lower limb were included in the study. Pre-operative CT scans of the affected limb and the normal contra-lateral side were obtained and 3D models of the patient's anatomy were created, using dedicated software. The healthy contralateral limb was mirrored and geometrically matched to the distal femur or proximal tibia of the healthy side. A virtual opening wedge correction of the affected bone was used to match the geometry of the healthy contralateral bone. Standard lower limb axes measurements confirmed correction of the alignment. Based on the virtual plan, surgical guides were designed to perform the planar osteotomy and achieve the planned wedge opening and hinge axis orientation. The osteotomy was fixed with locking plates and screws. Post-operative assessment included planar X-rays, CT-scan and full leg standing X-rays. One three-planar, three bi-planar and four single-plane osteotomies were performed. Maximum weightbearing mechanical femoro-tibial coronal malalignment varied between 7° varus and 14° valgus (mean 7.6°, SD 3.1). Corrective angles varied from 7°–15° (coronal), 0°–13° (sagittal) and 0°–23° (horizontal). The maximum deviation between the planned pre-operative wedge angle and the executed post-operative wedge angle was 1° in the coronal, sagittal and horizontal plane. The desired mechanical femorotibial axis on full-leg standing X-rays was achieved in 6 patients. Two patients were undercorrected by 1° and 2° respectively. Conclusion. 3D planning and guided correction of multi-planar deformity of femur or tibia is a feasible and accurate novel technique

Introduction. Osteotomies around the knee are traditionally templated on 2D plain X-rays. Results are often inaccurate and inconsistent and multiplanar ostetomies are hard to perform. The aim of this study is to evaluate the feasibility and accuracy of virtual three-dimensional CT-based planning and correct execution of osteotomies around the knee with the aid of patient specific surgical guides and locking plates. Methods. Eight consecutive patients with significant malalignment of the lower limb were included in the study. Pre-operative CT scans of the affected limb and the normal contra-lateral side were obtained and 3D models of the patient's anatomy were created, using dedicated software. The healthy contralateral limb was mirrored and geometrically matched to the distal femur or proximal tibia of the healthy side. A virtual opening wedge correction of the affected bone was used to match the geometry of the healthy contralateral bone. Standard lower limb axes measurements confirmed correction of the alignment. Based on the virtual plan, surgical guides were designed to perform the planar osteotomy and achieve the planned wedge opening and hinge axis orientation. The osteotomy was fixed with locking plates and screws. Post-operative assessment included planar X-rays, CT-scan and full leg standing X-rays. Results. One three-planar, three bi-planar and four single-plane osteotomies were performed. Maximum weightbearing mechanical femoro-tibial coronal malalignment varied between 7° varus and 14° valgus (mean 7.6°, SD 3.1). Corrective angles varied from 7°-15°(coronal), 0°–13°(sagittal) and 0°–23°(horizontal). The maximum deviation between the planned pre-operative wedge angle and the executed post-operative wedge angle was 1° in the coronal, sagittal and horizontal plane. The desired mechanical femorotibial axis on full-leg standing X-rays was achieved in 6 patients. Two patients were undercorrected by 1° and 2° respectively. Conclusion. 3D planning and guided correction of multi-planar deformity of femur or tibia is a feasible and accurate novel technique

Background. Osteotomies around the knee have been used to correct lower limb mal-alignment for over 50 years. The procedure is technically demanding and carries specific risks of neurovascular injury, incorrect planning and execution, and insufficient fixation. In recent years, with the advent of locking plates, fixation techniques have improved significantly but the correct planning and execution of the operation remains difficult. Despite the availability of CT and MRI 3D imaging, surgical planning is still traditionally performed on 2D plain X-rays [1]. Especially with multi-planar deformities, this technique is prone to error. The aim of this clinical pilot study is to evaluate the feasibility of virtual pre-operative three-dimensional planning and correct execution of osteotomies around the knee with the aid of patient specific surgical guides and locking plates. Patients and methods. Eight consecutive patients, presenting with significant malalignment of the lower limb were included in the study. Pre-operative CT scans of the affected limb and the normal contra-lateral side were obtained and 3D models of the patient's anatomy were created, using dedicated software (Mimics® 3-matic®, Materialise, Leuven Belgium) [2]. These models were used to evaluate the required surgical correction. The healthy contralateral limb was mirrored and geometrically matched to the distal femur or proximal tibia of the healthy side. A virtual opening wedge correction of the affected bone was used to match the geometry of the healthy contralateral bone. Standard lower limb axes measurements confirmed correction of the alignment [3]. Based on the virtual plan, surgical guides were designed to perform the planar osteotomy and achieve the planned wedge opening and hinge axis orientation (see figure 1). Apart from guiding the osteotomy, the patient specific surgical guide also guided drilling of the planned screw holes. Post-operative assessment of the correction was obtained through planar X-rays, CT-scan and full leg standing X-ray. Results. One three-planar, three bi-planar and four single-plane osteotomies were performed. All guides could be used during surgery and served accurate guidance of the osteotomy plane and screwholes. The guides matched the bone very well in all cases without remaining toggle. The maximum deviation between the planned pre-operative wedge angle and the executed post-operative wedge angle was 1° in the coronal, sagittal and horizontal plane. The desired mechanical femorotibial axis on full-leg standing X-rays was achieved in 6 patients. Two patients were undercorrected by 1° and 2° respectively. No significant peri-operative complications occurred. Conclusion. 3D planning and guided correction of multi-planar deformity of femur or tibia is a feasible and accurate novel technique

Aims

Total hip arthroplasty (THA) is considered the preferred treatment for displaced proximal femoral neck fractures. However, in many countries this option is economically unviable. To improve outcomes in financially disadvantaged populations, we studied the technique of concomitant valgus hip osteotomy and operative fixation (VOOF). This prospective serial study compares two treatment groups: VOOF versus operative fixation alone with cannulated compression screws (CCSs).

Introduction. Senile kyphosis arises from anterior ‘wedge’ deformity of thoracolumbar vertebrae, often in the absence of trauma. It is difficult to reproduce these deformities in cadaveric spines, because a vertebral endplate usually fails first. We hypothesise that endplate fracture concentrates sufficient loading on to the anterior cortex that a wedge deformity develops subsequently under physiological repetitive loading. Methods. Thirty-four cadaveric thoracolumbar “motion segments,” aged 70–97 yrs, were overloaded in combined bending and compression. Physiologically-reasonable cyclic loading was then applied, at progressively higher loads, for up to 2 hrs. Before and after fracture, and again after cyclic loading the distribution of compressive loading on the vertebral body was assessed from recordings of compressive stress along the sagittal mid-plane of the adjacent intervertebral disc. Vertebral deformity was assessed from radiographs at the beginning and end of testing. Results. Initial overload usually fractured a vertebral endplate, at 2.31 kN (STD 0.85). There was minimal anterior wedging, but pressure in the nucleus of the adjacent disc was reduced by 65.2% on average, and relatively elevated in the annulus and neural arch. Subsequent cyclic loading then caused anterior wedge deformity of the vertebral body, with the height of the anterior and posterior cortex decreasing by 34.3% (13.2) and 12.7% (7.5) respectively, and wedge angle increasing from 5.0° (3.76) to 11.4° (3.93) (all p<0.001). Discussion and Conclusion. Our hypothesis is supported: initial minor damage facilitates progressive anterior wedge deformity by transferring compressive loading on to the anterior cortex. Detecting initial endplate damage is important to minimise subsequent vertebral deformity in patients with osteoporosis. No conflicts of interest. Sources of funding: Funding was provided by a Royal College of Surgeons of England Research Fellowship and by the Gloucestershire Arthritis Trust. This work was presented at the British Orthopaedic Research Society Meeting

Introduction. Senile kyphosis arises from anterior ‘wedge’ deformity of thoracolumbar vertebrae, often in the absence of trauma. It is difficult to reproduce these deformities in cadaveric spines, because a vertebral endplate usually fails first. We hypothesise that endplate fracture concentrates sufficient loading on to the anterior cortex that a wedge deformity develops subsequently under physiological repetitive loading. Methods. Thirty-four cadaveric thoracolumbar “motion segments,” aged 70–97 yrs, were overloaded in combined bending and compression. Physiologically-reasonable cyclic loading was then applied, at progressively higher loads, for up to 2 hrs. Before and after fracture, and again after cyclic loading the distribution of compressive loading on the vertebral body was assessed from recordings of compressive stress along the sagittal mid-plane of the adjacent intervertebral disc. Vertebral deformity was assessed from radiographs at the beginning and end of testing. Results. Initial overload usually fractured a vertebral endplate, at 2.31 kN (STD 0.85). There was minimal anterior wedging, but pressure in the nucleus of the adjacent disc was reduced by 65.2% on average, and relatively elevated in the annulus and neural arch. Subsequent cyclic loading then caused anterior wedge deformity of the vertebral body, with the height of the anterior and posterior cortex decreasing by 34.3% (13.2) and 12.7% (7.5) respectively, and wedge angle increasing from 5.0° (3.76) to 11.4° (3.93) (all p<0.001). Discussion and Conclusion. Our hypothesis is supported: initial minor damage facilitates progressive anterior wedge deformity by transferring compressive loading on to the anterior cortex. Detecting initial endplate damage is important to minimise subsequent vertebral deformity in patients with osteoporosis. 256 words (250 excluding section headings) Acknowledgements Funding was provided by a Royal College of Surgeons of England Research Fellowship and by the Gloucestershire Arthritis Trust

Purpose of the study: The purpose of this study was to confirm long-term changes in frontal alignment after wedge osteotomy(even for with an «ideal» postoperative wedge angle of 3–6°), that the frontal alignment is correlated with functional degradation and also with femorotibial skeletal torsion. Material and methods: A non-consecutive retrospective series of 70 patients aged 57.5 on average at surgery for medial open-wedge tibial osteotomy were reviewed at 10–25 years. Goniometry measurements were obtained in the upright position after healing. Tibial and femoral torsion values were measured on the CT scan. Functional outcome at last follow-up was noted good, fair or poor. Results: Postoperatively 80% percent of the knees presented frontal realignment within the 3–6° range. At last follow-up frontal alignment had changed on average 10° for 40% of knees. The change in frontal alignment resulted from a deterioration of the medial or lateral joint space and in 80% was associated with poor functional outcome. Knees which preserved valgus of 3–6° at last follow-up had statistically better results than the rest of the series. There was a correlation between valgus frontal misalignment and femoral torsion greater than 14° (anteversion) and between varus frontal misalignment and femoral torsion less than 14°. There thus appeared to be a linear correlation between postoperative changes in the correction and femoral torsion. Conclusion: Good functional outcome of open wedge tibial osteotomy is correlated with stability of the axial correlation over time. Achieving postoperative valgus of 3–6° does not appear to be sufficient for stable axial correction. To achieve long-term preservation of the axial correction, it would be preferable to modulate the postoperative correction according to the degree of femoral torsion

Introduction: Painful anterior vertebral wedge “fractures” can occur without any remembered trauma, suggesting that vertebral deformity could accumulate gradually through sustained loading by the process of “creep”. If the adjacent intervertebral discs are degenerated, they press unevenly on the vertebral body in a posture- dependent manner, producing differential creep of the vertebra. We hypothesise that differential creep due to sustained asymmetrical loading of a vertebral body can cause anterior vertebral wedge deformity. Materials And Methods: Eleven thoracolumbar motion segments aged 64–88 yrs were subjected to a 1.5 kN compressive force for 2 hrs, applied via plaster moulded to its outer surfaces. Specimens were positioned in 2° flexion to simulate a stooped posture. Reflective markers attached to pins inserted into the lateral cortex of each vertebral body enabled anterior, middle and posterior vertebral body heights to be measured at 1Hz using an optical tracking device. Compressive ‘stress’ acting vertically on the vertebral body was quantified by pulling a miniature pressure transducer along the midsagittal diameter of adjacent discs. Results: Elastic deformation (strain) was higher anteriorly (−2018 ± 2983 μ strain) than posteriorly (−1675 ± 1305 μ strain). Creep strain (−2867 ± 2527 μ strain) was significantly higher anteriorly (p< 0.05) than posteriorly (−1164 ± 1026 μ strain), and was associated with a higher compressive stress in the anterior annulus of the adjacent disc. Non-recoverable creep deformations were significantly higher anteriorly (p< 0.05), and were equivalent to a wedging angle of 0.01–0.3°. Conclusion: Creep can cause anterior wedge deformity of the vertebral body. In the long term, accumulating creep could cause more severe (and painful?) deformity

BACKGROUND. Osteoporosis with subsequent osteoporotic vertebral compression fractures is an increasingly important disease due not only to its significant economic impact but also to the increasing age of our population. Pain reduction and stabilization are of primary importance with osteoporotic vertebral compression fractures. OBJECTIVE. To compare the efficacy and safety of balloon kyphoplasty and vertebroplasty for the treatment of vertebral compression fractures. MATERIALS & METHODS. From January 2004 to December 2009, 142 patients (32 males and 110 females), from 54 to 84 years old (mean age 67.4) were treated for 185 osteoporotic vertebral fractures of the thoracic or lumbar spine (level of fracture at Th5 or lower), with back pain for more than 8 weeks, and a visual analogue scale (VAS) score of 5 or more. Twenty-two patients (29 fractures) were lost at follow-up period and excluded. Patients were randomly allocated to percutaneous kyphoplasty (64%) or vertebroplasty (36%). All fractures were analyzed for improvement in sagittal alignment (Cobb angle, kyphotic angle, sagittal index, vertebral height). The patients were evaluated using the visual analog scale (VAS) and the Oswestry Disability Score. Radiographs were performed postoperatively, and at 1, 3, 6, and 12 months. RESULTS. The score according to pain, the patient's ability to ambulate independently and without difficulty, and the need for medications improved significantly (P < 0.001) after kyphoplasty or vertebroplasty. No significant difference could be found between both groups for the mean VAS and ODI preoperative and postoperative. Vertebral body height and kyphotic wedge angle of the T-L spine were also improved (p < 0.001); although kyphosis correction seems to be improved better in kyphoplasty than vertebroplasty. The rate of leakage was 12% for kyphoplasty and 32% for vertebroplasty; nevertheless most of the leakage was clinically asymptomatic and the rate of serious problems remained low (pulmonary embolism 0.01% kyphoplasty vs 0.6% vertebroplasty). New fractures in the next 6 months at the adjacent vertebrae were observed ∼ 15% in both groups. More PMMA was used in the kyphoplasty group than in the vertebroplasty group (5.5 +/− 0.8 vs. 4.1 +/− 0.5 mL, p < 0.001). Operation time was longer in balloon kyphoplasty compared to vertebroplasty (mean time 20±5min/vertebral fracture in group B vs 30±5min in group A). CONCLUSION. Both balloon kyphoplasty and vertebroplasty provided a safe and effective treatment for pain and disability in patients with vertebral compression fractures due to trauma or osteoporosis. Balloon kyphoplasty led to an ongoing reduction of fractured vertebrae and was followed by a lower rate of cement leakage

Purpose: Analysis of the sagittal balance of the spine is a fundamental step in understanding spinal disease and proposing appropriate treatment. The objectives of this prospective study were to establish the physiological values of pelvic and spinal parameters of sagittal spinal balance and to study their interrelations. Material and methods: Two hundred fifty lateral views of the spine taken in the standing position and including the head, the spine and the pelvis were studied. The following variables were noted: lumbar lordosis, thoracic kyphosis, sagittal tilt at 9, sacral slope, pelvic incidence, pelvic version, intervertebral angle, and the vertebral wedge angle from T9 to S1. These measures were taken after digitalising the x-rays. Two types of analysis were performed. A descriptive univariate analysis was used to characterise angular parameters and a multivariate analysis (correlation, principal component analysis) was used to compare interrelations between the variables and determine how economic balance is achieved. Results and discussion: Mean angular values were: maximal lumbar lordosis 61±12.7°, maximal thoracic kyphosis 41.4±9.2°, sacral slope 42±8.5°, pelvic version 13±6°, pelvic incidence 55±11.2°, sagittal tilt at T9 10.5±3.1°. There was a strong correlation between sacral slope and pelvic incidence (r=0.8), lumbar lordosis and sacral slope (r=0.86), pelvic version and pelvic incidence (r=0.66), lumbar lordosis pelvic incidence pelvic version and thoracic kyphosis (r=0.9), and finally between pelvic incidence and sagittal tilt at T9, sacral slope, pelvic version, lumbar lordosis, and thoracic kyphosis (r=0.98). Multivariate analysis demonstrated three independent parameters influencing sagittal tilt at T9, reflecting the lateral balance of the spine. The first was a linear combination of the pelvic incidence, lumbar lordosis and sacral slope. The second was pelvic version and the third thoracic kyphosis. Conclusion: This work provides an aid for analysis and comprehension of anteroposterior imbalance observed in spinal disease and also to calculate with the linear regression equations describing the corrections to be obtained with treatment