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Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_9 | Pages 21 - 21
1 May 2017
Sargazi N Adamson E Cheung G
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Background Hip fractures are one of the leading causes of hospital admissions. Surgical treatment is often associated with significant blood loss, requiring post-operative erythrocyte transfusion. Aim To assess post-operative erythrocyte transfusion rates for hip fractures and evaluate the effect of tranexamic acid (TXA).

Method

All patients undergoing surgical repair of a hip fracture at RLBUHT between 1st April 2013 – 30th April 2014 were selected. Data regarding transfusion status and peri-operative TXA use was collected from electronic databases and case notes.

Results

450 patients were admitted with a hip fracture, of whom 441 underwent surgery. Modalities of hip fixation included total hip replacement (THR, n=39), hemiarthroplasty (n=145), dynamic hip screw (DHS, n=116), cannulated hip screw (CHS, n=17) and long (n=71) and short (n=53) intramedullary hip screw (IMHS). 44.2% received a post-operative erythrocyte transfusion, with an average of 2.5 units per patient (range 1–9 units). With all study subjects included, the average transfusion rates for THR, hemiarthroplasty, DHS, CHS, long IMHS and short IMHS were 0.44 units, 0.78 units, 0.97 units, 0.47 units, 1.55 units and 1.19 units respectively. Data regarding intra-operative TXA administration was available for 318 (72.1%) patients, sixty-one of whom received TXA. 27.9% given TXA required a post-operative transfusion (range 0–6 units), compared to 35.4% of patient with no intra-operative TXA (range 0–11 units), p=0.142.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_III | Pages 299 - 299
1 Jul 2011
Kerin C Cheung G Graham N Cool P
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Background: There are no evidence based guidelines on the surveillance of cemented total hip arthroplasty. We reviewed the outcomes of those patients undergoing this procedure in 1996 & 1997.

Methods: The patients were identified from theatre log books. The follow up date was then retrieved from the electronic patient record system used at our institution. From these we recorded the age, sex, side of procedure, evidence of radiological loosening & time of revision surgery. The data with regards to radiological evidence of loosening & revision surgery were then analysed using a ® statistical software package. From this we were able to plot Kaplan-Meier survival & hazard plots.

Results: We identified 425 primary total hip arthroplasties. Using radiological evidence of loosening as the end point we found that there was an initial peak and a peak at 8 years. There was a 10 year survival rate of 85.8%. Using revision surgery as the end point we found that there was, again, an initial peak & a peak at 8 years. There was a 10 year survival rate of 91.5%.

Conclusions: Once the patient has made it through the first post operative year they do not need to be followed up again until 8 years assuming they remain asymptomatic.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 169 - 169
1 May 2011
Cheung G Miller D Wilson L Meyer C Kerin C Ford D
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The treatment of unstable distal radius fractures remains controversial. Volar locking plates provide stable fixation using the fixed angle device principle. More recently this technique has gained increasing popularity with several reports demonstrating good results. We present our experience from the first 259 patients performed at this institution.

Method: Local Ethics Committee approval was obtained prior to the onset of the study. Theatre records and implant forms were used to recruit all patients in whom a Distal Volar Radius (DVR) Plate, (DePuy, Leeds, United Kingdom) was used for an unstable distal radius fracture between August 2005 and February 2008. Surgery was performed either by a consultant, or a specialist registrar. Two hundred and fifty nine consecutive patients were identified. Six patients had bilateral distal radius fractures. Patient records were reviewed, and each patient contacted via a postal questionnaire and Patient-Rated Wrist Evaluation (PRWE). Other outcome measures included return to work and complication rate.

Results: Of the 259 patients 160 responses were received, response rate 62%. The mean follow up was 30.8 months, (Range 18–48). The mean age of the patients was 57.3 years (Range 16–93). The mean inpatient stay was 1.6 days, (mode 1 day). The median PRWE was 3; (range 0–83) and the mode was 0. Ninety four of the patients had a PRWE of ≤5. Seventy one out of 78 patients (91%) returned to the same job. The mean return to work was 40.6 days (SD37.5).

There were 13 minor complications in total (7.8%). Six patients had extensor tendon irritation, of which two patients required extensor tendon reconstruction. One further patient had a spontaneous EPL rupture which was not associated with prominent metal work. Four (2.4%) patients had median nerve symptoms postoperatively. Two patients subsequently required carpal tunnel decompression, the other two settled spontaneously. Two (1.2%), patients developed Complex Regional Pain Syndrome. One patient developed a minor superficial wound infection.

In all, 9 (5.4%) patients had removal of their metalwork, 6 for tendon irritation, 2 for wrist stiffness (one which was positioned too distally) and 1 for pin penetration into the joint.

Discussion: Our results show that the DVR plate can be used reliably with good results and an early return to high levels of function. This is the largest series to date of the use of this distal volar locking plate.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_I | Pages 54 - 54
1 Jan 2011
Gilbert R Cheung G Carrothers A Richardson J
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Conversion of failed femoral components of total hip resurfacing to conventional hip replacement is reportedly a straightforward procedure. There is little published to qualify this and what is available suffers from small study numbers and various combinations pre and post-operative implants.

Between 1997 and 2002, the Oswestry Outcome Centre prospectively collected data on 5000 Birmingham Hip Resurfacings (BHRs) performed by 141 surgeons, at 87 hospitals. To date 4526 have survived, 135 died and 165 are lost to follow-up. 174 have been revised, of which 60 were failures of the femoral component. We reviewed modes of failure and post-revision clinical outcomes in this sub-group.

Isolated femoral component failure accounted for 60 hips (1.2%). 28 femoral neck fractures, 14 femoral head collapses, 13 femoral component loosenings, 3 avascular necroses (AVN), 1 femoral loosening followed by fracture and 1 dislocation. Mean time to revision surgery was 2.6 years (1.8 years for neck fracture; 3.4 years femoral loosening, head collapse and AVN). All acetabular components were left in situ. At revision surgery 25 cemented, 25 uncemented and 10 unknown femoral prostheses were used with 56 BHR modular heads, 2 custom-made Exeter heads and 2 Thrust Plate heads. 47 patients completed outcome scores post-revision surgery. Median modified Harris Hip Score was 82 (IQ range=63–93) and Merle d’Aubigne score was 14 (IQ= 9.5–15) at a mean follow up of 3.9 years post-revision. The 4526 surviving resurfacings had a median hip score of 96 (IQ=87–100) p≤4.558x10-8 and median Merle score of 17 (IQ=14–18) p≤1.827x10-7. Mean 7.0 years follow up. There was no difference in outcomes between cemented and un-cemented revision components nor were there differences between fractured neck of femur and femoral loosening, head collapse or AVN.

Following revision of the femoral component to a conventional hip replacement, function is significantly worse than surviving resurfacings.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 521 - 521
1 Oct 2010
Kerin C Cheung G Cool P Graham N
Full Access

Background: There are no evidence based guidelines on the surveillance of cemented total hip arthroplasty. We reviewed the outcomes of those patients undergoing this procedure in 1996 & 1997.

Methods: The patients were identified from theatre log books. The follow up date was then retrieved from the electronic patient record system used at our institution. From these we recorded the age, sex, side of procedure, evidence of radiological loosening & time of revision surgery. The data with regards to radiological evidence of loosening & revision surgery were then analysed using a XXX statistical software package. From this we were able to plot Kaplan-Meier survival & hazard plots.

Results: We identified 425 primary total hip arthroplasties. Using radiological evidence of loosening as the end point we found that there was a peak initially and a peak at 8 years. There was a 10 year survival rate of 85.8%. Using revision surgery as the end point we found that there was, again, an initial peak & a peak at 8 years. There was a 10 year survival rate of 91.5%.

Conclusions: Once the patient has made it through the first post operative year they do not need to be followed up again until 8 years assuming they remain asymptomatic.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 388 - 388
1 Jul 2010
Cheung G Oakley J Bing A Carmont M Graham N Alcock R
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Introduction: Primary total hip replacement remains one of the commonest orthopaedic procedures performed. It is yet to be clearly demonstrated whether use of a postoperative drain is of benefit in these procedures.

Methods: We carried out a prospective randomised study comparing the use of autologous reinfusion drains, closed suction drains or no drain to determine their influence on allogenic blood transfusion requirements, length of hospital stay and infection rates. Stratification was carried out for confounding factors.

Results: 153 patients were recruited into the study and randomised to one of the three closely matched groups. There was no significant difference between the mean intra-operative blood loss or post-operative haemaglo-bin levels between the 3 groups. 42% of the suction drain group required post-operative transfusion as compared to 17% of the reinfusion drain group and 12% of the group with no drains. This difference was highly significant (P=0.02) Mean time for the wound to become dry was 3 days, 3.9 days and 4 days in the no drain, re-transfusion drain and suction drain groups respectively. This difference was statistically significant (P=0.03). There was no statistically significant difference in the mean length of inpatient stay.

Discussion: This study demonstrates a significantly higher transfusion rate with closed suction drains compared to reinfusion drains or no drains. With the drive to reduce hospital stay our study supports the considered use of no drain or a reinfusion drain.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 390 - 390
1 Jul 2010
Gilbert R Cheung G Carrothers A Richardson J
Full Access

Introduction: Conversion of failed femoral components of total hip resurfacing to conventional hip replacement is reportedly a straightforward procedure. There is little published to qualify this and what is available suffers from small study numbers and various combinations pre and post-operative implants.

Method: Between 1997 and 2002, the Oswestry Outcome Centre prospectively collected data on 5000 Birmingham Hip Resurfacings (BHRs) performed by 141 surgeons, at 87 hospitals. To date 4526 have survived, 135 died and 165 are lost to follow-up.

174 have been revised, of which 60 were failures of the femoral component.

We reviewed modes of failure and post-revision clinical outcomes in this sub-group.

Results: Isolated femoral component failure accounted for 60 hips (1.2%). 28 femoral neck fractures, 14 femoral head collapses, 13 femoral component loosenings, 3 avascular necroses (AVN), 1 femoral loosening followed by fracture and 1 dislocation. Mean time to revision surgery was 2.6years (1.8years for neck fracture; 3.4years femoral loosening, head collapse and AVN).

All acetabular components were left in situ. At revision surgery 25 cemented, 25 uncemented and 10 unknown femoral prostheses were used with 56 BHR modular heads, 2 custom-made Exeter heads and 2 Thrust Plate heads.

47 patients completed outcome scores post-revision surgery. Median modified Harris Hip Score was 82 (IQ range=63–93) and Merle d’Aubigne score was 14 (IQ= 9.5–15) at a mean follow up of 3.9years post-revision.

The 4526 surviving resurfacings had a median hip score of 96 (IQ=87–100) p≥4.558x10-8 and median Merle score of 17 (IQ=14–18) p≥1.827x10-7. Mean 7.0 years follow up.

There was no difference in outcomes between cemented and uncemented revision components nor were there differences between fractured neck of femur and femoral loosening, head collapse or AVN.

Discussion: Following revision of the femoral component to a conventional hip replacement, function is significantly worse than surviving resurfacings.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 283 - 283
1 May 2010
Cheung G Arbuthnot J Higgins G Balain B Dennehy T Trevett M
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We prospectively assessed a consecutive series of patients undergoing MTPJ arthroplasty with the MOJE prosthesis. All patients entered into the study were assessed preoperatively with the AOFAS 100-point Hallux Meta-tarsophalangeal-Interphalangeal Joint Scale and the range of motion was recorded. Patients were assessed on table postoperatively for range of motion (ROM) and then at 3, 12 and 24 months with AOFAS scores and ROM.

Forty-two toes (40 patients) were recruited into the study. There were 24 women and 16 men. The mean patient age on the day of surgery was 59 (range 37 to 73). 18 operations were carried out on the left hallux and 24 on the right. All operations were carried out for a diagnosis of hallux rigidus (although one patient also had hallux valgus, with an intermetatarsal angle of 24° and a hallux valgus angle of 40°).

The mean pre-op AOFAS score increased from 36.0 to 82.2 at 3 months (p< 0.001) and was 87.0 at 12 months and 84.2 at 24 months. There was no significant change in scores from 3 months onwards. Only 2 patients had a follow-up of 36 months; both of them had AOFAS scores of 95.

The mean arc of motion reduced from 70.8° on-table to 33.3° by 24 months (p< 0.001). The difference in arc of motion from 3 months to 12 months was a decrease from 45.6 to 40.0 which was borderline significant.

In 4 radiographs there was evidence of progressive loosening (figure 4). This was at 24 months in all 4 cases. For 3 of the patients the AOFAS score was 85. For the 4th patient the AOFAS score was 65

One patient had a spontaneous fusion of the toe. There were also three episodes of wound breakdown, one patient had intra-operative division of the EHL tendon that was repaired. We also noted post-operatively that: three feet developed Morton’s neuromata; one patient developed tarsometatarsal joint osteoarthritis of the great toe, one sesamoid osteoarthritis and one plantar fasciitis.

At the most recent follow-up appointment 33 out of 40 patients (82.5%) were satisfied with the results of their operation, 2 were dissatisfied (5%) and results regarding satisfaction were not available for 5 patients.

The results obtained in this paper demonstrate good, prospective, short-term results with the press-fit zirconium ceramic Moje implant. We believe that in the correct patient group good short term results can be achieved in the treatment of 1st MTPJ osteoarthritis as an alternative to fusion, particularly in those patients who are unwilling to have permanent stiffness in this joint for cosmetic or functional reasons


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 37 - 38
1 Mar 2008
Roth S Mousavi P Cheung G Chow E Finkelstein J Whyne C
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The impact of cement leakage during percutaneous vertebroplasty has not been well characterized. This study aimed to quantify and compare cement leakage and its clinical significance in osteoporotic and metastatic vertebrae treated with vertebroplasty. Cement leakage was quantified using semi-automated thresholding of digital CT scans for fouteen metastatic and nineteen osteoporotic vertebrae and compared to pain scores. Cement leakage was present in 90.9% of vertebrae. Cement leaked predominantly into the disc in the osteoporotic vertebrae but yielded more diffuse leakage patterns in the metastatic cases. Despite cement leakage, there was significant improvement in pain immediately following vertebroplasty for all patients.

This study aimed to quantify cement leakage in osteoporotic and metastatic vertebrae post-vertebroplasty and to determine whether leakage has clinical significance at follow-up.

Despite high incidences of cement leakage, both osteoporotic and metastatic patients experienced significant immediate pain relief post-vertebroplasty.

Cement leakage is investigated as a possible rationale for the higher rates of pain relief seen in osteoporotic vs metastatic patients undergoing percutaneous vertebroplasty.

Cement leakage was present in 90.9% of the vertebrae treated. The percent volume of cement leakage was 11.6±10.6 in the osteoporotic vertebrae and 19.4±19.1 in the metastatic vertebrae (p=0.144). Cement leaked predominantly into the disc in the osteoporotic vertebrae whereas leakage was more diffuse in the metastatic vertebrae. Pain scores were high prior to vertebroplasty and decreased significantly following the procedure in both groups irrespective of leakage (p< 0.05).

Digital CT scans were retrieved for osteoporotic (n=19) and metastatic (n=14) patients treated with percutaneous vertebroplasty. Volume of cement injected directly into the vertebral body and location of cement leakage (pedicle, disc, periphery, canal) was quantified using semi-automated thresholding techniques. Pain scores were collected at four stages of treatment (pre, immediately post, one day post, one week post-vertebroplasty).

Disruption of the endplate in the osteoporotic spine provides an easily accessible pathway for the leakage of cement into the disc. Elevated pressurization during cement injection into metastatically involved vertebrae may account for the more diffuse cement leakage seen in the metastatic group. Clinically, pain scores improved irrespective of leakage.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 71 - 71
1 Mar 2008
Zalzal P Cheung G Bhandari M Spelt J Papini M
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Femoral nails are thought to be load sharing devices. However, the specific load sharing characteristics and associated stress concentrations have not yet been reported in the literature. The purpose of this study was to use a validated, three dimensional finite element model of a nailed femur subjected to gait loads in order to determine the resulting stresses in the femur and the nail. The results showed that load was shared between the nail and the bone throughout the gait cycle. In addition, high stress concentrations were noted in the bone around the screw holes, and dynamization was of minimal benefit.

To determine the stresses in the bone and nail in a femur with a locked, retrograde, intramedullary nail.

The retrograde femoral nail is a load sharing device. High stress concentrations occur in the bone around locking screw holes. When only one locking screw is used proximally and distally, stresses in the implant are excessive and may lead to failure. Dynamization was of minimal benefit.

This is the first study to use a validated three dimensional finite element model to provide a detailed biomechanical analysis of stress patterns in a retrograde nailed femur under gait loads. The results can help resolve issues of stress shielding, implant removal, number of locking screws and dynamization.

In the fully locked condition, loads in the femur were significantly higher than those in the nail for most of the gait cycle. Removal of locking screws to obtain dynamization only increased axial load in the femur by 17 %. However, stresses in the locking screws increased by as much as 250% when fewer than 4 screws were used. Maximum stresses in the bone were found around screw holes.

A three dimensional finite element model of the femur and nail was developed. The model was validated by comparing results to a physical saw bone model instrumented with strain gages and subjected to a simple a compressive load. Once good correlation with simple loading patterns was demonstrated, gait loading patterns obtained from literature were incorporated and simulations were run for various conditions.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_III | Pages 382 - 382
1 Oct 2006
Cheung G Moorehead J Butcher C
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Introduction: Pedobarograph systems are used to measure foot pressure characteristics during gait. These measurements help clinicians diagnose pathology and assess treatment outcome. While most patients can walk across the Pedobarograph footplate unaided, some patients ask if they can use their crutch.

Aim: The aim of this study was to assess the effect of using a crutch on pedobarograh measurements.

Materials and Methods: A Musgrave Pedobarograph system was used to measure the foot pressure characteristics of twenty feet in ten normal subjects. The group’s mean age and weight were 31 years (SD=6) and 78 kg (SD=12), respectively. Each subject had each of their feet measured 3 times as they walked across the foot plate unaided. These measurements were then repeated with the subject using a crutch on the contralateral side to that being measured. The force through the crutch was recorded using a set of scales to ensured consistency between measurements.

Results: The main foot pressure characteristics are listed below. The table shows the mean value of the normal parameter, along with the percentage difference of the mean values when the crutch was used. The results of a paired-t test are also given to indicate the statistical significance of the change.

In addition to the above quantitative changes, qualitative assessment of the data showed an alteration in the loading pattern with reduced push off forces. However, eighteen of the twenty feet showed no alteration in the pattern of pressure distribution.

Conclusion: These results show that a crutch affects normal gait by generally increasing the time parameters and reducing the load and pressure parameters. The only parameters not significantly affected by the crutch were “Push off duration” and “Time to peak heel strike pressure”.