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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 342 - 342
1 Sep 2012
Migaud H Marchetti E Combes A Puget J Tabutin J Pinoit Y Laffargue P
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Introduction

The same cup orientation is classically applied to all cases of hip replacement (45° abduction, 20° anteversion). We hypothesize that this orientation must be adapted to the patient's hip range of motion. We tested this hypothesis by means of an experimental study with respect to hip range of motion, comparing the classical orientation (45° and 20°), and the orientation obtained with computer-assisted navigation.

Material and Methods

The experimental model included a hemipelvis equipped with a femur whose mobility was controlled for three configurations: stiff (60°/0°, 15°/10°, 10°/10°), average (80°/10°, 35°/30°,35°/25°), mobile (130°/30°, 50°/50°, 45°/35°). The hemipelvis and the cup holder were equipped with an electromagnetic system (Fastrack ™) to measure cup orientation. The Pleos™ navigation system (equipping the hemipelvis, the femur, and the cup holder) guided the cup orientation by detecting the positions risking impingement through a kinematic study of the hip. Nine operators each performed 18 navigation-guided implantations (162 hip abduction, anteversion, and range of movement measurements) in two series scheduled 2 months apart.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 298 - 298
1 May 2010
Girard J Marchetti E May O Laffargue P Pinoit Y Bocquet D Migaud H
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Introduction: The prosthetic impingement occurs if the range of motion of the hip exceeds implant mobility or in case of component malorientation. This phenomenon is rarely studied in the literature and most data have come from sporadic cases. This study was designed to assess the frequency and the risk factors of this phenomenon.

Material: The frequency and the severity of the impingement were calculated from a continuous series of 413 cups retrievals. These cups were examined macroscopically twice by two independent observers. The cam effect was noted as: absent, grade 1 (visible at gross inspection but measuring < 1 mm), grade 2 (notch measuring 1–3 mm), grade 3 (notch measuring > 3 mm). The risk factors were analyzed for 298 retrievals that had complete clinical charts.

Results: Among the 413 cups explants, the frequency of impingement was 51.3 percent (grade 3 in 12% and grade 2 in 24%). The impingement was the reason for removal in only 1.7 percent (only for hard bearings), meaning that impingement was mainly an unexpected event (98.3 percent). The impingement was more frequent when revisions were performed because of instability (80 percent; odd-ratio 4.2 (1.1–16.2)) than for loosening (52%) osteolysis (59%) or infection (38%) (p =.002). Likewise, impingement was more frequent when the sum of hip motion exceeded 200 degrees (sum of motion in the 6 degrees of freedom of the hip) (66% versus 45% if the sum was below 200°). The other risk factors were: use of heads with skirts (78% versus 55%), liner with an elevated rim (73% versus 55%), and head-neck ratio below 2.

Discusssion and conclusion: This study underlines the impingement is common when assessing cup retrievals (over 50 percent). One should be aware of impingement when performing hip replacement in patients having a high range of motion. This situation may require prostheses with a high head-neck ratio, as well as use of computer-assisted surgery. One should avoid liners with elevated rim as well as heads with skirts to prevent dislocation, particularly when other risk factors are detected.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 305 - 306
1 May 2010
May O Soenen M Laffargue P Girard J Migaud H
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Introduction: Cementless revision hip arthroplasties require a stable initial fixation that does not compromise a subsequent bone reconstruction. In case of severe femoral bone loss, stems usually requires distal fixation that may induce stress shielding and finally reduce the spontaneous bone reconstruction. We introduced the use of distally locked revision stems in 1993 hoping strong fixation and bone reconstruction. The goal of the current study was to assess if these components fulfill these two objectives.

Materials and Methods: 101 cementless femoral revision stems with distal locking by screws (Ultime™ Wright-Cremascoli) were inserted from 1993 to 2001. These stems were smooth distally and porous coated with or without HA 1/3 proximally. The indication to use these components was severe bone loss (Paprosky grade IIC and III in 51%) when press fit distal fixation could not be obtained. The use of bone graft was limited to segmental defects or to treat trochanteric non-union. An extended trochanteric osteotomy was performed in 89%. The revision was performed because of aseptic loosening in 43,4%, periprosthetic fracture in 24,2% and infected loosening in 25,2%. The results were assessed after a mean follow-up of 6 years (5–12).

Results: 13 patients deceased and 2 were lost for follow-up. All the extended trochanteric osteotomies healed. Merle d’Aubigné hip score increased from 8.3 to 13.4, but thigh pain was observed in 44%. Bone reconstruction was significant according to Hoffman index at 3 levels of assessment. The 5-year survivorship was 87% considering aseptic revision for any reason. Seventeen repeated femoral procedures were performed: 9 related to thigh pain (because there was no proximal osteointegration) that were revised for short primary stems, 8 because of stem fractures (all occurred at the level of the proximal hole with the same stem size because there was no proximal fixation as long as the stems were smooth or without HA-coating.

Discussion: This serie has the longest follow-up using locked revision stems. Despite severe pre-operative bone loss, primary fixation and significant bone reconstruction were obtained for all the cases without extensive bone grafting. The major weakness, thigh pain and stem break, were related to unadequate femoral coating for these cementless stems that did not achieved osteointegration. Conversly, the reoperations were simple, allowing the use of short primary designs as bone reconstruction was achieved in all cases without extensive bone grafting. These locked stems allow a strong primary distal fixation that does not compromise bone regeneration. An improvement of femoral coating (extension to 2/3 and use of hydroxyapatite) may reduce the rate of thigh pain and reoperation.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_II | Pages 309 - 310
1 May 2010
Riera P Girard J May O Duquennoy A Laffargue P Migaud H
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Purpose of the study: The incidence of revision hip arthroplasty is increasing. In order to overcome certain problems related to loss of femoral bone stock, an original technique was developed combining fragmented allograft material and a metallic mesh with a non filling stem cemented distally in a healthy zone to ensure stability.

Materials and Methods: The clinical data (Postel-Merle-d’Aubigné, PMA score) and radiographic findings (implant migration, loss of bone stock using the SOFCOT and PAPROSKY classification, quality of cementing, filling, and graft aspect, graft lysis, periprosthetic lucency, final aspect of the graft) were collected retrospectively. The operation and the technical difficulties and intraoperative complications were noted.

Results: We report a series of 32 hips treated with this technique and having a mean follow-up of 12.5 years (range 8–20 years). The population studied had particularly significant bone loss (78.2% SOFCOT stage 3 and4). These hips underwent revision for aseptic loosening. The implantation technique required a femoral window in 39.1%. Preventive cerclage was often used (39.1%) but did not prevent fracture or missinsertion in 30.4%. The PMA score improved significantly from 10.6 (7–18) preoperatively to 17 (12–18) at last follow-up. Radiologically, femoral bone regeneration at last follow-up had an aspect of corticalisation in 63.6% of hips, and of cancellous trabeculation in 36.4%. Femoral implant survival was 100% at eight years, and 92.8±6.88% at mean follow-up of 12.5 years. There was only one revision at eleven years for secondary osteolysis related to polyethylene wear in a very active subject implanted before the age of 50 years.

Discussion: The clinical and radiographic results are very satisfactory for this series of femoral revisions using an impacted fragmented graft material and with the longest follow-up reported in the literature. Distal fixation limited migration observed when the stem is entirely cemented in the graft, but did not affect reconstruction which demonstrated long-term stability. This technique, initiated in 1986 without a specific instrument set, had now demonstrated its long-term reliability. The only problem is the length of the operation and the complications related to femoral preparation.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 104 - 104
1 Mar 2009
PINOIT Y MAY O GIRARD J EDDINE TA LAFFARGUE P MIGAUD H
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Introduction: The anterior pelvic plane (APP), described by Lewinnek, is defined by the following points : anterior iliac spines, pubic symphysis. This plan is mostly considered as vertical in weight bearing and is currently used as the reference to guide cup insertion by means of imageless computer assistance (CAS). However, to our knowledge, there is no data that strongly confirm APP is vertical in weight bearing and how much his orientation is modified with regards operative position, or THA insertion. This study assessed these data by means of a radiological analysis.

Material and Methods: The orientation of the APP was measured with regards to the vertical plane on weight-bearing profile X-rays of the pelvis in 106 subjects including:

1) 82 patients with THA (40 who had at least one dislocation, and 42 matched patients without instability randomly selected, 19 of these 42 underwent a profile X-ray of the pelvis before and after THA insertion)

2) and 24 standard subjects who underwent lying and weight-bearing profile X-rays of the pelvis to assess the modifications of orientation of the pelvis between these two positions.

Results: Thirty-eight percent of the subjects in weight-bearing had an orientation of the APP different of more than ± 5° from vertical plane and 13% were out of the interval ±10°. The orientation of the APP was not significantly different between the groups (standard and THA) nor between the groups who had stable or unstable THA. The orientation of the APP was significantly modified between lying and weight-bearing posture, from a mean of 1,2° lying to −2,25° upright. Under these conditions, 12 subjects presented a variation of more than 7°. Insertion of a THA did not significantly modify the orientation of the APP in weight-bearing among the 19 subjects (variations were small (−1° ± 7° [from – 21° to 8°]), but were more than 5° for 7 of the 19 subjects).

Discussion and Conclusion: Most of the surgeons use the APP as a reference to guide navigation for cup insertion, considering it is vertical in weight-bearing. However, it is not true for 38% with a margin of 10°, which is equivalent to approximately half of the anatomical anteversion of the acetabulum. Standing up produced a significant variation of the orientation of the APP with regards to lying position. These errors that are not integrated by most of the CAS without preoperative CT scans, may produce cam effect or dislocation when the patient is moving to sited position. The variations of APP orientation with regards to vertical plane suggest it is not adequate to guide the CAS insertion of the cup. There is no reliable reference, easily identifiable during surgery that integrates the variations of position of the pelvis. This leads us to promote a new CAS for THA insertion free of reference plane, based on kinematics.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 243 - 243
1 Jul 2008
PINOIT Y MIGAUD H LAFFARGUE P TABUTIN J GIRAUD F PUGET J
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Purpose of the study: Most systems used for computer-assisted total hip arthroplasty require preparatory computed tomography acquisition or use of multiple bone markers fixed on the pelvis. In order to overcome these problems, we developed a novel system for CT-free computer assisted hip surgery based on a functional approach to the hip joint. The concept is to orient the cup within a cone describing hip motion. The purpose of the present study was to analyze preliminary results obtained with this new system.

Material and methods: This new system was used to implant 18 primary total hip arthroplasties in 16 women and 2 men (mean age 68±7.8 years, age range 54–83 years) with degenerative disease. Two optoelectronic captors were fixed percutaneously on the pelvis and the distal femur. The acetabulum was reamed, then the femur prepared with instruments of increasing caliber. The last reamer positioned in the shaft carried an upper head which matched the size of the prepared acetabulum. Hip joint motion was recorded to determine the cone of maximal hip mobility. The system then oriented the cup so that this cone was completely included the cone described by the prosthesis.

Results: There was one traumatic posterior dislocation (fall in stairs) at three weeks, without recurrence. The Postel Merle d’Aubigné score improved from 8±2.9 (3–12) preoperatively to 17±0.8 (16–18) at last follow-up. None of the patients complained about the sites where the percutaneous markers were inserted and ther were no cases of hematoma or fracture. Mean leg length discrepancy was 5.6±7.5 mm (range 0–25 mm) before surgery and 0.6±3 mm (range −5 to 10 mm) at last follow-up. Mean anteversion of the femoral implant was 22.3±6.7° (14–31). Anatomic anteversion of the cup (measured from a marker linked to the pelvis and thus independently of the position of the pelvis) was 25.9±10.4° (12–40). The sum of the femoral and acetabular anteversions was 48.2±14.6° (range 27–71°).

Conclusion: This method can be used in routine practice without lengthening operative time excessively. It provides a safe way to control the length of the limb and helps position the cup. This study demonstrated that there is no ideal position for the cup that can be applied for all patients. Because of the wide spread of the inclination and anteversion figures, half of the cases were outside the safety range recommended by Lewinnek.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 267 - 267
1 Jul 2008
MIGAUD H PINOIT Y HERENT S SOENEN M BACHOUR F MAY O LAFFARGUE P DUHAMEL A DEVOS P
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Purpose of the study: In order to evaluate the influence of prosthesis design and resurfacing on the outcome of total hip arthroplasty (THA) implanted without cement, we reviewed the orthopedic literature from 1980 to 2004.

Material and methods: The PubMed database was screened from 1980 to 2004 for publications reporting cementless THA with a follow-up analysis. The same criteria were used to screen three registries. In all, the publications retained had studied 50,162 cementless THA (mean patient age 48.9 years, mean follow-up 6.5 years) where were studied according to rate of revision, presence of osteolysis, and presence of operative fractures. Eleven families of components grouped together the majority of prostheses: five acetabular families [screw fixation without resurfacing (n=2997), screw fixation with hydroxyapatite (HA) resurfacing (n=3618), screw fixation with corindon resurfacing (2360), press-fit mac-roporous (15691), press-fit HA (6094)]; and six families of femoral pivots [straight macroprous (n=7502), straight HA (n=3255), straight corindon (n=6136), anatomic HA (n=3468), anatomic macroporous (n=1215), anatomic corindon (n=1041)].

Results: The rates of revision and of osteolysis were higher for screw fixed cups without resurfacing. For screw fixed or press-fit cups, HA resurfacing did not reduce the rate of revision compared with corindon coated or macroporous implants. For anatomic pivots, adjunction of HA resurfacing reduced the rate of revision but at the shortest follow-up and without reducing the rate of osteolysis. Corindon-coated pivots gave comparable results for straight or anatomic implants. Conversely, HA-coated pivots gave better results with an anatomic design. The shape of the pivot had les effect than resurfacing on osteolysis and revision, but had a greater influence on operative fractures (2.9% for straight implants versus 4.6% for anatomic versions).

Conclusion: In all:

uncoated implants should be abandoned;

HA resurfacing does not reduce the rate of revision and can be associated with a higher rage of osteolysis;

there is no advantage between screw fixed or press-fit cups as long as the cup has a quality resurfacing;

there is no real difference between straight and anatomic pivots except that intraoperative fracture can be lower for the straight implants.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 109 - 109
1 Mar 2008
Girard J Migaud H Chantelot C Laffargue P Duquennoy A
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Thirty-nine cementless hip replacements using metal-on-metal articulation were consecutively implanted in thirty patients less than fifty years of age and compared with a matched control group of cementless replacements using ceramic-on-polyethylene articulation. The Harris hip score at follow-up (minimum five years) for the metal-on-metal was 94.9 (range, 74–100). After the same follow-up, the results of the ceramic-on-polyethylene were significantly worse: nine osteolyses and seven surgical revisions related to wear. Five-year survival rates were 97% +/− 2% for the ceramic-on-polyethylene and 100% for the metal-on-metal. The metal-on-metal may be recommended to prevent wear problems in younger and more active patients.

The aim of the current study was to assess the results of metal-on-metal articulating components inserted as a primary hip replacement in patients under the age of fifty, comparated with a matched control group using ceramic-on-polyethylene.

Patients and methods

The inclusion of patients was: under fifty years of age and a diagnosis of arthrosis or necrosis of the femoral head.

Femoral stem and cup migration was detected. A variation over five millimeters between the follow-up radiographs was considered as migration.

At the follow-up in 2003, the cobalt concentrations in the whole blood were assessed in the metal-on-metal cohort. The detection limit of cobalt in the whole blood was 0.06 μg/L.

None of the components had migration.

At a mean follow-up of sixty-nine months, the median concentration of cobalt in the whole blood was 0.62μg/L. Only eight patients had cobalt levels greater than 1 μg/L.

Considering a reoperation with the exchange of one of the components as end point, the five year survival rates were 100% for the metal-on-metal group and 97% + 2 for the ceramic-on-polyethylene group. Our study suggests that the metal-on-metal articulation gives a significant improvement in terms of resistance to wear when compared with these conventional bearing components. Our results suggest the metal-on-metal articulation with cementless components can be recommended in the young and active patient to prevent the occurrence of wear and osteolysis. A careful assessment of patients with high levels of whole-blood cobalt should be performed.

Funding: Aucun


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 124 - 124
1 Apr 2005
Migaud H Jobin A Laffargue P Giraud F Pinoit Y Duquennoy A
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Purpose: In young active subjects, total hip arthroplasty (THA) raises the risk of early polyethylene wear eventually warranting the use of alternative bearings. The purpose of this study was to analyze outcome in subjects aged less than 50 years implanted with a primary metal-on-metal prosthesis.

Material and methods: Between 1995 and 1998, thirty-nine THA with a metal-on-metal bearing were implanted without cement in 30 consecutive patients aged less than 50 years, mean age 23–50). There were nine bilateral implantations. The cementless implants had surface treatment without hydroxyapatite and 28 mm heads. The indication for THA was necrosis in twenty cases, osteoarthritis in nineteen, most in patients with hip dysplasia. The Devane classification placed 84% of the patients in levels 4 or 5, indicating heavy work and/or sports activities. Inclusion criteria were: 1) age less than 50 years, 2) significant activity (occupation and/or sports), 3) osteoarthritis or necrosis. Patients were included and followed prospectively. Serum cobalt level was measured at last follow-up. None of the patients were lost to follow-up.

Results: The Postel-Merle-d’Aubigné score (PMA) improved from 12.8±2.2 (7–15) before surgery to 17.2±1 (14–18) at 5.1 years (5–6.3). None of the patients complained of hip pain. Two patients has moderate inguinal pain related to a cupiliopsoas conflict. All patients achieved complete weight bearing on the fourth postoperative day excepting three who resumed weight bearing at six weeks due to an acetabular augmentation graft. There were no cases of implant migration and all implants exhibited signs of osteointegration on the radiograms. There were no postoperative dislocations and no cases of osteolysis could be identified, particularly in the eight patients who had increased serum cobalt (four bilateral implants) and who had no other statistically significant favouring factor.

Conclusion: The results at five years suggest that the second-generation metal-on-metal bearing is a reliable alternative when THA is proposed for young active subjects. Long-term follow-up of this cohort of subjects at high risk of wear is necessary to confirm these encouraging results.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 244 - 245
1 Mar 2004
Senneville E Migaud H Nallet I Laffargue P Savage C Dubreuil L
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Aims: Rosenow’s broth is an enriched liquid medium used at laboratory for culture of anaerobes. It has never been tested for transport and culture of bacteria, particularly those that are frequently involved in chronic prosthetic infections. This prospective study assessed these data. Methods: 154 intraoperative specimens and joint aspirations were harvested between 1998 and 2000 in 80 patients that had infected knee (24) or hip (56) prostheses. For each of the 154 specimens there was a standard and a Rosenow recipient. Culture obtained on agar medium was called “direct culture” (DC) and culture from any liquid medium was called after “enrichment” (AE). The similitude between bacteria isolated from different specimens was assessed. Results: A bacteria was isolated from DC in 59 specimens (38%) and after AE in 95 specimens (62%). Among the 59 positive DC there was agreement between standard and Rosenow in 87%, and no agreement in 13% [ Staphylococcus sp. (6), Pseudomonas sp.(1) Enterobacteriacae (1)]. Among the 95 cultures AE, Rosenow and standard cultures were in agreement in 41 (43,1%), only standard was positive in 13 (13,6%), but only Rosenow’s broth was positive in 41 (43,1%) with negative standard cultures [16 Staphylococcus sp(13 S. epidermidis), 5 Streptococcus sp., 2 Enterococcus sp., 1 Corynebacterium sp, 3 Enterobacteriacaeand 14 anaerobes]. Sensibility and predictive positive value of Rosenow were respectively 0.86 and 0.86. Conclusion: This study suggest the accuracy of the Rosenow’s broth for transport and culture as agreement was observed in 87% with the DC that is considered as the “gold standard”. When only cultures AE were positive, the Rosenow’s broth corrected the diagnosis in 43%, particularly for infections related to S. epidermidis-and anaerobes.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 337 - 337
1 Mar 2004
Tirveilliot F Migaud H Gougeon F Laffargue P Maynou C Fontaine C
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Aims: Three methods of mobilization are currently performed: arthroscopic release (AR), manipulation under general anesthesia (MUGA), open surgical release (OSR). This study assessed the accurate indications of these 3 procedures to treat stiff knee arthroplasties. Methods: Sixty-two of these procedures were performed between 1989 and 2001 and followed at least 1 year: 34 MUGA, 18 AR and 10 OSR. The 3 groups were comparable excepted for the delay between the prosthetic insertion and the mobilization procedure: 17 weeks for MUGA, 46 weeks for AR, 97 weeks for OSR. All the patients had the same postoperative analgesia and rehabilitation program. Results: For the 62 procedures there was an improvement in range of ßexion from preop-erative (mean 58.4¡) to follow-up (mean 94.6¡) and a decrease in ßessum deformity from 7.6¡ to 2.5¡ (p= 0.001). From surgery to 1 year of follow-up, there was a decrease in ßexion (104.6¡ to 94.6¡) and an increase in ßessum deformity (1.3¡ to 2.5¡) (NS). The worst postoperative ranges of motion were observed at 6 weeks after the procedure, and then an improvement was observed up to 6 months but was non-signiþcant. Flexion did not improved beyond 6 months after the procedure. The results of the 3 techniques were not signiþcantly different. However, failures were more frequent when MUGA were performed beyond 8 weeks after prosthetic insertion, and when AR were performed beyond 6 months after prosthetic insertion (p< 0.01). Conclusions: We recommend to treat stiff total knee prostheses by MUGA until 8 weeks after insertion, by AR between 8 weeks and 6 months, and by OSR later on. This protocol addresses stiff prostheses without infection and without component malposition. The deþnitive ranges of motions were obtained at 6 months after mobilization.