An intra-articular steroid injection can be a useful diagnostic tool in patients presenting with debilitating hip pain and radiographically mild osteoarthritis. The clinical and patient reported outcomes associated with patients who have radiographically mild osteoarthritis and undergo total hip arthroplasty (THA) remain poorly studied. Patients undergoing primary, elective THA at a single academic medical center by a fellowship-trained adult reconstruction surgeon between 2017–2023 were identified. Only those patients who underwent an intra-articular corticosteroid injection into the operative hip within one year of surgery were included. Patients were divided into two cohorts based on the severity of their osteoarthritis as determined by preoperative radiographs; those with Kellgren-Lawrence (KL) grade I-II arthritis were classified as “mild” whereas those with KL grade III-IV arthritis were classified as “severe”. Clinical and patient reported outcomes at final follow-up were compared between cohorts. The final cohorts included 25 and 224 patients with radiographically mild and severe osteoarthritis, respectively. There were no baseline differences in age, gender or time between intra-articular corticosteroid injection and THA between cohorts. There were no significant differences in the preoperative or postoperative HOOS JR values between patients with mild or severe arthritis (all Patients with radiographically mild osteoarthritis who feel relief of their hip pain following an intra-articular corticosteroid injection report similar preoperative debility and demonstrate similar improvements in patient reported outcome scores following THA compared to patients with radiographically severe osteoarthritis.
Uncemented highly porous titanium implants have been shown to promote osseointegration, and may result in a durable construct for total knee arthroplasty (TKA). Given the mixed results of uncemented TKA, it is important to evaluate the early stability for this product. The objective of the following study was to use radiostereometric analysis (RSA) to assess early fixation of a highly porous tibial baseplate and metal backed patella. Twenty-seven patients (mean age 64 years, 30% female) undergoing primary TKA consented to participate in this prospective cohort study. All patients received a highly porous tibial baseplate, a metal backed patella and tantalum RSA bone markers. Implant migration was assessed using model-based RSA at 1.5, 3, 6, 12 and 24 months post-operative. Patient reported outcome measures were captured using the same follow-up schedule, and compared to pre-operative measures.Introduction
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The purpose of this randomized controlled trial is to evaluate the efficacy of using dilute betadine versus sterile saline lavage in aseptic revision total knee (TKA) and hip (THA) arthroplasty to prevent acute postoperative deep periprosthetic joint infection (PJI). Of the 450 patients that were randomized, 5 did not have 90-day follow-up, 9 did not receive the correct treatment, and 4 were excluded for intraoperative findings consistent with PJI. 221 Patients (144 knees and 77 hips) received saline lavage only and 211 (136 knees and 75 hips) received a three-minute dilute betadine lavage (0.35%) prior to wound closure. Patients were observed for the incidence of acute postoperative deep PJI within 90 days of surgery. Statistical analysis was performed using t-tests or Fisher's exact test where appropriate. Power analysis determined that 285 patients per group are needed to detect a reduction in the rate of PJI from 5% to 1% (alpha=0.05, beta=0.20). There were seven PJIs in the saline group and one in the betadine lavage group (3.2% vs. 0.5%, p=0.068). There were no significant differences in any baseline demographics between groups suggesting appropriate randomization. Although we believe the observed difference between treatments is clinically relevant, it was not statistically significant with the sample size enrolled thus far and enrollment is ongoing. Nonetheless, we believe that these data suggests that dilute betadine lavage is a simple method to reduce the rate of acute postoperative PJI in patients undergoing aseptic revision procedures.
The treatment of severe acetabular bone loss is challenging, especially in the setting of an associated chronic pelvic discontinuity. There are several available treatment options for chronic pelvic discontinuity, each of which has its own disadvantages. One of the major difficulties with this entity, regardless of the reconstructive technique chosen, is the inability to obtain reproducible healing of the discontinuity. We evaluated the use of acetabular distraction, a technique which achieves peripheral or lateral distraction and central or medial compression across the discontinuity. We recommend acetabular distraction to allow for implantation of a stable construct, achieve biologic fixation and increase the likelihood of discontinuity healing. In this multi-center trial, 32 patients that underwent acetabular revision for a chronic pelvic discontinuity using acetabular distraction were radiographically evaluated at a minimum of 25 months (range, 25 to 160 months). The study cohort was categorized according to the Paprosky acetabular bone loss classification: seven (22%) type IIC, five (16%) type IIIA, and 20 (62%) type IIIB defects. Fourteen (70%) of the 20 patients with a type IIIB acetabular bone loss pattern required use of augments for acetabular reconstruction. Of the 32 patients, 1 (3%) patient required a revision for aseptic loosening, 2 (6%) patients had evidence of radiographic loosening but were not revised, and 3 (9%) patients had migration of the acetabular component into a more stable position. Radiographically, 22 (69%) of the cohort demonstrated healing of the discontinuity. The Kaplan-Meier construct survivorship was 83.3% when using aseptic acetabular loosening as an end-point. During this study, the authors created a new pelvic discontinuity classification based on the type of reconstruction required. The classification mirrors the Paprosky acetabular bone loss classification. A Type I chronic pelvic discontinuity required jumbo cup reconstruction without augments. A type II discontinuity required the use of an augment for an extracavitary defect. A type III discontinuity required an augment for an intracavitary defect. Type III defects were further subdivided into type IIIA and IIIB discontinuity. Type IIIA discontinuities utilized an augment to reconstruct the anterosuperior and/or posteroinferior column defect for primary stability of the overall construct. Type IIIB discontinuities utilized augments to reconstruct the anterosuperior and/or posteroinferior column defect for primary stability as well as a posterosuperior augment for supplemental fixation. All augments were unitized to the cup with cement. Type IV defects were massive defects that required the use of two orange-slice augments, secured together with screws and placed centrally to restore the defect, and a cup implanted and unitized to the augments with cement. According to this new classification, the discontinuity reconstructions in our study were classified as follows: 12 (38%) type I, 8 (25%) type II, 6 (19%) type IIIA, 6 (19%) type IIIB, and 0 as type IV. Acetabular distraction technique demonstrates favorable radiographic outcomes with reproducible discontinuity healing in a majority of cases. This alternative technique allows for biologic fixation and intra-operative customization of the construct to be implanted based on the bone loss pattern present following component removal.
Modular tapered implants have been suggested as the optimal treatment in patients with severe femoral bone loss undergoing revision total hip arthroplasty (THA). The purpose of this study is to describe minimum 2 year follow up of patients treated with modular tapered prostheses for Paprosky type IIIB and IV femoral bone loss in revision THA. 44 Consecutive patients with Paprosky type IIIB (23) or IV (21) femurs undergoing revision total hip arthroplasty to cementless modular tapered prostheses were studied. Harris Hip Scores were obtained prior to revision on all patients except those presenting with acute implant failure or periprosthetic fracture. 10 Patients were deceased within 2 years of surgery; the remaining 18 were followed for an average of 42 months (range 25-69 months). Clinical outcomes were measured using the Harris Hip Score, and radiographs were assessed for signs of stem loosening or subsidence >4mm.Introduction
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When using press-fit stems in revision total knee arthroplasty (TKA), diaphyseal engagement optimizes stability. Attempts to maximize press fit may lead to periprosthetic fracture; however, the literature offers no guidance regarding the prevalence or management of this complication. The purpose of this study is to report the incidence, risk factors, and outcomes of these fractures. 634 Stemmed implants (307 femoral and 327 tibial) from 413 consecutive revision TKAs were reviewed. Immediate and 6 week post-operative radiographs were examined. Patient age, gender, stem length, diameter, and offset were evaluated as potential risk factors for fracture occurrence using a paired t-test for continuous and a chi-square analysis for categorical variables.Introduction
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Serum erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), and synovial fluid white blood cell (WBC) count and differential are effective in diagnosing periprosthetic joint infection (PPJI); however their utility in patients with inflammatory arthritis is unknown. The purpose of this study is to determine the utility of these tests in patients with inflammatory arthritis. 934 Consecutive revision hip and knee arthroplasties were prospectively evaluated for PPJI. 202 Cases were excluded due to acute post-operative or hematogenous infection. 690 Patients had non-inflammatory and 42 had inflammatory arthritis. Receiver operating characteristic (ROC) curves were used to establish optimal ESR, CRP, WBC, and % neutrophil values for diagnosis of PPJI, and the area under the curve (AUC) was calculated to determine the overall accuracy.Introduction
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