Aims

Higher osteoblastic bone activity is expected in aseptic loosening and painful unicompartmental knee arthroplasty (UKA). However, insights into normal bone activity patterns after medial UKAs are lacking. The aim of this study was to identify the evolution in bone activity pattern in well-functioning medial mobile-bearing UKAs.

Objectives

Elevated proximal tibial bone strain may cause unexplained pain, an important cause of unicompartmental knee arthroplasty (UKA) revision. This study investigates the effect of tibial component alignment in metal-backed (MB) and all-polyethylene (AP) fixed-bearing medial UKAs on bone strain, using an experimentally validated finite element model (FEM).

INTRODUCTION. Osteoarthritis (OA) is a growing societal burden, due to the ageing population. Less invasive, less damaging, and cheaper methods for diagnosis are needed, and sound technology is an emerging tool in this field. AIMS. The aim of the current research was to: 1) investigate the potential of visual scalogram analysis of Acoustic Emission (AE) frequencies within the human audible range (20–20000 Hz) to diagnose knee OA, 2) correlate the qualitative visual scalogram analysis of the AE with OA symptoms, and 3) to do this based on information gathered during gait. METHODS. The analysis was carried out on a database collected during a prospective sound study on healthy and osteoarthritic knees. Sound recordings obtained with a contact microphone mounted on the patella and attached to a digital pre-amplifier, whilst patients were walking on a treadmill, were visualised, manually sampled, and transformed into scalograms. Features of the scalograms were described and qualitatively analysed through chi-squared tests for association with healthy or OA knees (knee status), and with severity of OA pain and functional symptoms and impact on quality of life (QoL), activities of daily living (ADL) and sports using the Knee Injury and Osteoarthritis Outcome Score (KOOS) subscales. RESULTS. 28 patients (56 knees) were included in the analysis. Our method provides a wide variety of different scalogram features: if no events were recorded, the scalogram was classified as “quiet” (Fig 1). In case of abnormal recordings, data analysis evaluated association with the total count of the three most common events that appeared: 1. Peak (Fig 2), 2. Scattered (Fig 3) or 3. Island (localized noise but not presenting as a peak) (Fig 4) – “scalogram features”. No association was found between global scalogram characteristics (quiet versus “any noise”) and knee status (healthy or OA) (χ. 2. =3.163, p=0.075), but was found between knee status and three specific scalogram features (χ. 2. =9.743, p=0.008). The strongest association was a higher frequency of the “scattered” feature in the OA group (χ. 2. =9.06, p=0.01). Scalogram characteristics had no significant association with the sports and recreation (χ. 2. =1.74, p=0.419) nor the activities of daily living (χ. 2. =1.80, p=0.406) KOOS subscales. Significant association was found between scalogram characteristic and the pain (χ. 2. =10.34, p=0.006), quality of life (χ. 2. =6.58, p=0.037), and symptoms (χ. 2. =7.54, p=0.023) subscales. CONCLUSION. Promising results from analysis of individual features and of KOOS subscales establish the potential of acoustic analysis in evaluation of OA knees. More analysis of the data is needed to better define the variety of scalogram features. The future consequences of this research would be the development of a fast and affordable, non-invasive, radiation-free and potentially portable approach to evaluation, diagnosis and longitudinal monitoring of knee disorders

INTRODUCTION. Osteoarthritis (OA) is a growing societal burden, due to the ageing population. Less invasive, less damaging, and cheaper methods for diagnosis are needed, and sound technology is an emerging tool in this field. Some studies investigate ultrasound signals, while others look at acoustic signals in the audible range. AIMS. The aim of the current research was to: 1) investigate the potential of visual scalogram analysis of Acoustic Emission (AE) frequencies within the human audible range (20–20000 Hz) to diagnose knee OA, 2) correlate the qualitative visual scalogram analysis of the AE with OA symptoms, and 3) to do this based on information gathered during gait. METHODS. The analysis was carried out on a database collected during a prospective sound study on healthy and osteoarthritic knees. Sound recordings obtained with a contact microphone mounted on the patella and attached to a digital pre-amplifier, whilst patients were walking on a treadmill, were visualised, manually sampled, and transformed into scalograms. Features of the scalograms were described and qualitatively analysed through chi-squared tests for association with healthy or OA knees (knee status), and with severity of OA pain and functional symptoms and impact on quality of life (QoL), activities of daily living (ADL) and sports using the Knee Injury and Osteoarthritis Outcome Score (KOOS) subscales. RESULTS. 28 patients (56 knees) were included in the analysis. Our method provides a wide variety of different scalogram features: if no events were recorded, the scalogram was classified as ‘quiet’ (Fig 1). In case of abnormal recordings, data analysis evaluated association with the total count of the three most common events that appeared: 1. Peak (Fig 2), 2. Scattered (Fig 3) or 3. Island (localized noise but not presenting as a peak) (Fig 4) – “scalogram features”. No association was found between global scalogram characteristics (quiet versus ‘any noise’) and knee status (healthy or OA) (χ. 2. =3.163, p=0.075), but was found between knee status and three specific scalogram features (χ. 2. =9.743, p=0.008). The strongest association was a higher frequency of the “scattered” feature in the OA group (χ. 2. =9.06, p=0.01). Scalogram characteristics had no significant association with the sports and recreation (χ. 2. =1.74, p=0.419) nor the activities of daily living (χ. 2. =1.80, p=0.406) KOOS subscales. Significant association was found between scalogram characteristic and the pain (χ. 2. =10.34, p=0.006), quality of life (χ. 2. =6.58, p=0.037), and symptoms (χ. 2. =7.54, p=0.023) subscales. CONCLUSION. Promising results from analysis of individual features and of KOOS subscales establish the potential of acoustic analysis in evaluation of OA knees. More analysis of the data is needed to better define the variety of scalogram features. The future consequences of this research would be the development of a fast and affordable, non-invasive, radiation-free and potentially portable approach to evaluation, diagnosis and longitudinal monitoring of knee disorders. For any figures or tables, please contact the authors directly

Objectives

Unicompartmental knee arthroplasty (UKA) is a demanding procedure, with tibial component subsidence or pain from high tibial strain being potential causes of revision. The optimal position in terms of load transfer has not been documented for lateral UKA. Our aim was to determine the effect of tibial component position on proximal tibial strain.

Objectives. Up to 40% of unicompartmental knee arthroplasty (UKA) revisions are performed for unexplained pain which may be caused by elevated proximal tibial bone strain. This study investigates the effect of tibial component metal backing and polyethylene thickness on bone strain in a cemented fixed-bearing medial UKA using a finite element model (FEM) validated experimentally by digital image correlation (DIC) and acoustic emission (AE). Materials and Methods. A total of ten composite tibias implanted with all-polyethylene (AP) and metal-backed (MB) tibial components were loaded to 2500 N. Cortical strain was measured using DIC and cancellous microdamage using AE. FEMs were created and validated and polyethylene thickness varied from 6 mm to 10 mm. The volume of cancellous bone exposed to < -3000 µε (pathological loading) and < -7000 µε (yield point) minimum principal (compressive) microstrain and > 3000 µε and > 7000 µε maximum principal (tensile) microstrain was computed. Results. Experimental AE data and the FEM volume of cancellous bone with compressive strain < -3000 µε correlated strongly: R = 0.947, R. 2. = 0.847, percentage error 12.5% (p < 0.001). DIC and FEM data correlated: R = 0.838, R. 2. = 0.702, percentage error 4.5% (p < 0.001). FEM strain patterns included MB lateral edge concentrations; AP concentrations at keel, peg and at the region of load application. Cancellous strains were higher in AP implants at all loads: 2.2- (10 mm) to 3.2-times (6 mm) the volume of cancellous bone compressively strained < -7000 µε. Conclusion. AP tibial components display greater volumes of pathologically overstrained cancellous bone than MB implants of the same geometry. Increasing AP thickness does not overcome these pathological forces and comes at the cost of greater bone resection. Cite this article: C. E. H. Scott, M. J. Eaton, R. W. Nutton, F. A. Wade, S. L. Evans, P. Pankaj. Metal-backed versus all-polyethylene unicompartmental knee arthroplasty: Proximal tibial strain in an experimentally validated finite element model. Bone Joint Res 2017;6:22–30. DOI:10.1302/2046-3758.61.BJR-2016-0142.R1

Objectives

Studies reporting specifically on squeaking in total hip arthroplasty have focused on cementless, and not on hybrid, fixation. We hypothesised that the cement mantle of the femur might have a damping effect on the sound transmitted through the metal stem. The objective of this study was to test the effect of cement on sound propagation along different stem designs and under different fixation conditions.

25–40% of unicompartmental knee replacement (UKR) revisions are performed for unexplained pain possibly secondary to elevated proximal tibial bone strain. This study investigates the effect of tibial component metal backing and polyethylene thickness on cancellous bone strain in a finite element model (FEM) of a cemented fixed bearing medial UKR, validated using previously published acoustic emission data (AE). FEMs of composite tibiae implanted with an all-polyethylene tibial component (AP) and a metal backed one (MB) were created. Polyethylene of thickness 6–10mm in 2mm increments was loaded to a medial load of 2500N. The volume of cancellous bone exposed to <−3000 (pathological overloading) and <−7000 (failure limit) minimum principal (compressive) microstrain (µ∊) and >3000 and >7000 maximum principal (tensile) microstrain was measured. Linear regression analysis showed good correlation between measured AE hits and volume of cancellous bone elements with compressive strain <−3000µ∊: correlation coefficients (R= 0.947, R2 = 0.847), standard error of the estimate (12.6 AE hits) and percentage error (12.5%) (p<0.001). AP implants displayed greater cancellous bone strains than MB implants for all strain variables at all loads. Patterns of strain differed between implants: MB concentrations at the lateral edge; AP concentrations at the keel, peg and at the region of load application. AP implants had 2.2 (10mm) to 3.2 (6mm) times the volume of cancellous bone compressively strained <−7000µ∊ than the MB implants. Altering MB polyethylene insert thickness had no effect. We advocate using caution with all-polyethylene UKR implants especially in large or active patients where loads are higher

Increased incidence of obesity and longer life expectancies will place increased demands on load bearing joints. In the present work, a method of pre-clinical evaluation to assess the condition of the joint and potentially inform on cases of joint deterioration, is described. Acoustic emission (AE) is a non-destructive test methodology that has been used extensively in engineering for condition monitoring of machinery and structures. It is a passive technique that uses piezoelectric sensors to detect energy released from internal structural defects as they deform and grow. The technique has been used with some success in the past to identify characteristic signals generated from the knee joint during activities such as standing and sitting, in candidate arthroplasty patients (1,2). In this study, 40 asymptomatic subjects had AE data generated from their knee joints analysed. Subject characteristics such as age, gender, and lifestyle were disclosed and evaluated against the AE data. Each subject was invited to take a seated position and a piezoelectric AE sensor (Pancom P15, 150kHz resonance, 19mm diameter) was attached to the subject's knee using a wax couplant and tape as close to the articulating surface and on a bony prominence to avoid signal attenuation in the soft tissue. Subjects were invited to sit and stand 3 times. AE data were collected and processed using an AMSY5 AE processor (Vallen, Germany). Tests were repeated on a separate occasion and selected subjects were invited to participate on a third occasion. The AE data of particular interest were the peak amplitudes and the frequency power spectrum of the waveform. Post-test inspection of subject characteristics allowed them to be separated into three broad categories: no previous history (group A), some instances of pain in the knee (group B), and those who have had previous minor surgery on the knee (group C). The corresponding AE results were grouped separately. It was found that groups A and B demonstrated similar signal amplitude characteristics while group C produced much higher, significantly different (p<0.05) amplitudes and amplitude distributions. Typical results are shown in figure 1. At present, broad trends could be identified and relationships emerged between the data and subject history (prior surgery, typical daily activity). Further work will continue with asymptomatic subjects and the work will be extended to pre-operative patients to identify whether certain trends are amplified in this population

Osteotomy in spine and skull base surgery is a highly demanding task that requires very high precision. Compared to conventional surgical tools, laser allows contactless hard tissue removal with fewer traumas to the patient and higher machining accuracy. However, a key issue remains unsolved: how to terminate the ablation while the underlying critical soft tissue is reached?. Our research group has realised a closed-loop control of a CO. 2. -laser osteotomy system under the guidance of an optical coherence tomography (OCT). The OCT provides three-dimensional information about the microstructures beneath the bone surface with a resolution on micrometre scale and an imaging depth of about 0.5 mm. The OCT and CO. 2. -laser systems are integrated using a coaxial setup and a registration between their working spaces (mean absolute error 19.6 μm) was performed. The laser ablation and OCT scan are performed in turn. After correction of image distortions and speckle noise reduction, the position of the critical structure can be segmented in the enhanced OCT scans. The laser parameters for the next round of ablation are foresightedly planned based on the overlying residual bone thickness. After patient motion compensation by tracking artificial landmarks in the OCT scans (accuracy: RMS 27.2 μm), the ablation pattern can be precisely carried out by the CO. 2. -laser. The system was evaluated by performing laser cochleostomy on native porcine cochlea and mean ablation accuracy of 30 μm has been achieved. However, for narrow incisions that are only several tens of micrometres wide, very few pixels are visible beneath the incision bottom in the OCT and a robust segmentation of the critical structure is impossible. We are now developing a hybrid control system, which monitors the ablation-induced acoustic emission (AE) as a secondary control mechanism in addition to the OCT. When a pre-defined “switching” depth is reached, the AE-based control module is activated. Instead of analysing the acquired signals with conventional Fourier transform, a wavelet transform-based approach has been developed, which compares the correlation coefficients of the wavelet spectra of successive laser pulses. At the transition from bone tissue to the underlying soft tissue layer, a significant change in the coefficients can be observed, which is regarded as the signal for terminating the ablation. In order to keep the injury to the soft tissue layer to a minimal level, the laser energy is reduced after the switching. Preliminary experiments revealed that the wavelet-based approach is capable of controlling the ablation using pulses with extremely low energy down to 0.04mJ/pulse, resulting in an injured tissue layer of less than 10 μm. We expect to achieve the ablation accuracy on tens of micrometre scale using the proposed hybrid control mechanism

The December 2013 Research Roundup³⁶⁰ looks at: Inflammation implicated in FAI; Ponseti and effective teaching; Unicompartmental knee design and tibial strain; Bisphosphonates and fracture healing; Antibiosis in cement; Zoledronic acid improves primary stability in revision?; Osteoporotic fractures revisited; and electroarthrography for monitoring of cartilage degeneration

As many as 25% to 40% of unicompartmental knee replacement (UKR) revisions are performed for pain, a possible cause of which is proximal tibial strain. The aim of this study was to examine the effect of UKR implant design and material on cortical and cancellous proximal tibial strain in a synthetic bone model. Composite Sawbone tibiae were implanted with cemented UKR components of different designs, either all-polyethylene or metal-backed. The tibiae were subsequently loaded in 500 N increments to 2500 N, unloading between increments. Cortical surface strain was measured using a digital image correlation technique. Cancellous damage was measured using acoustic emission, an engineering technique that detects sonic waves (‘hits’) produced when damage occurs in material. Anteromedial cortical surface strain showed significant differences between implants at 1500 N and 2500 N in the proximal 10 mm only (p < 0.001), with relative strain shielding in metal-backed implants. Acoustic emission showed significant differences in cancellous bone damage between implants at all loads (p = 0.001). All-polyethylene implants displayed 16.6 times the total number of cumulative acoustic emission hits as controls. All-polyethylene implants also displayed more hits than controls at all loads (p < 0.001), more than metal-backed implants at loads ≥ 1500 N (p < 0.001), and greater acoustic emission activity on unloading than controls (p = 0.01), reflecting a lack of implant stiffness. All-polyethylene implants were associated with a significant increase in damage at the microscopic level compared with metal-backed implants, even at low loads. All-polyethylene implants should be used with caution in patients who are likely to impose large loads across their knee joint. . Cite this article: Bone Joint J 2013;95-B:1339–47

Joint registries report that 25–40% of UKR revisions are performed for pain. Proximal tibial strain and microdamage are possible causes of this “unexplained” pain. The aim of this study was to examine the effect of UKR implant design and material on proximal tibial cortical strain and cancellous microdamage. Composite Sawbone tibias were implanted with cemented UKR components: 5 fixed bearing all-polyethylene (FB-AP), 5 fixed bearing metal backed (FB-MB), and 5 mobile bearing metal backed implants (MB-MB). Five intact tibias were used as controls. Tibias were loaded in 500N increments to 2500N. Cortical surface strain was measured using digital image correlation (DIC). Cancellous microdamage was measured using acoustic emission (AE), a technique which detects elastic waves produced by the rapid release of energy during microdamage events. DIC showed significant differences in anteromedial cortical strain between implants at 1500N and 2500N in the proximal 10mm only (p<0.001) with strain shielding in metal backed implants. AE showed significant differences in cancellous microdamage (AE hits), between implants at all loads (p=0.001). FB-AP implants displayed significantly more hits at all loads than both controls and metal backed implants (p<0.001). FB-AP implants also differed significantly by displaying AE hits on unloading (p=0.01), reflecting a lack of implant stiffness. Compared to controls, the FB-AP implant displayed 15x the total AE hits, the FB-MB 6x and the MB-MB 2.7x. All-polyethylene medial UKR implants are associated with greater cancellous bone microdamage than metal backed implants even at low loads

The analysis of hip joint vibrations (phonoarthrography, vibration arthrometry, vibroarthrography, hip auscultation) has been explored as a means to assess joint pathologies, disease status and recently, incipient prosthesis failure. Frequencies < 100Hz have been used to diagnose gross pathology and wear in knee prostheses, frequencies from 1k to 10k Hz for progression of osteoarthritis, and frequencies > 10k Hz for loosening of cemented hip prostheses. It is possible that detailed analysis of higher frequencies could detect and quantify the smaller geometric changes (asperities) that develop in articular prosthetic wear. We examined the ultrasound emission generated by various types of hip prostheses and native hips of 98 patients. The ultrasonic transducer was attached to the skin over the greater trochanter with a hypoallergenic, transparent dressing using a standard acoustic coupling gel layer on the microphone face to improve skin contact. The transducer was attached by a 2m cord to a battery operated, data recorder/logger. The patients were asked to sit in a chair, rise, sit again and then rise and take 5 steps while recording the acoustic data from these two movements of sitting and walking. This procedure was repeated for the opposite hip in each patient as well. Acoustic emission analysis examined frequency distributions and power spectrums of the recorded signals and their relations to prosthesis type and implantation time. Review of x-rays of prosthetic and native hips was carried out with OA grading and prosthetic wear quantification. We have obtained data on 79 metal-polyethylene (average duration of 8.5 years; 0.1–28), 20 ceramic-ceramic (average duration of 8.5 years; 0.5–10), 17 metal-metal (average duration of 1.2 years; 0.1–5.5) and 15 ceramic-polyethylene (average duration of 0.6 years; 0.1–1) hip arthroplasties as well as 75 native hips. Analysis of the data enabled us to tell the difference between patients whose native hips did not cause them any discomfort and those patients with painful osteoarthritis (initial findings indicate that OA severity can be quantified as well). The measurements of wear of the metal-polyethylene prostheses obtained from patients’ x-rays were compared to an analysis of the ultrasonic emissions, a homogeneity showed no significant differences (all p’s > 0.24) between the curve type and amount of wear of the prosthesis polyethylene. Our data suggests that we are capable of assessing the status of OA by acoustic emission. Further analysis of wear data coupled to ultrasonic emission is needed for accurate quantification of THA wear

The Acoustic Emission (AE) technique has been described as possessing ‘many of the qualities of an ideal damage-monitoring technique’, and the technique has been used successfully in recent years to aid understanding of failure mechanisms and damage accumulation in bone cement during de-bonding of the cement-metal interface fatigue loading, pre-load cracking during polymerisation and to describe and locate damage within an entire stem construct. However, most investigations to date have been restricted to in-vitro testing using surface mounted sensors. Since acoustic signals are attenuated as they travel through a material and across interfaces, it is arguable that mounting the sensors on the bone surface to investigate damage mechanisms occurring within the bone cement layer is not ideal. However, since direct access to the bone cement layer is not readily available, the bone surface is often the only practical option for sensor positioning. This study has investigated the potential for directly embedding AE sensors within the femoral stem itself. This enables a permanent bond between the sensor and structure of interest, allows closer proximity of the sensor to the region of interest, and eliminates potential complications and variability associated with fixing the sensor to the sample. Data is collected during in-vitro testing of nominal implanted constructs, and information from both embedded and externally mounted AE sensors are compared and corroborated by microComputed Tomography (micro-CT) images taken both before and after testing. The use of multiple AE sensors permitted the location as well as the chronology of damage events to be obtained in real time and analysed without the need for test interruption or serial sectioning of the test samples. Parametric analysis of the AE signal characteristics enabled those events likely to be associated with cracking as opposed to interfacial rubbing or de-bonding to be differentiated and it was shown that the embedded sensors gave a closer corroboration to observed damage using micro-CT and were less affected by unwanted sources of noise. The results of this study have significant implications for the use of AE in assessing the state of total hip replacement (THR) constructs both in-vitro and potentially in-vivo. Incorporating the sensors into the femoral stem during in-vitro testing allows for greater repeatability between tests since the sensors themselves do not need to be removed and re-attached to the specimen. To date, all in-vivo studies attempting to use the AE technique to monitor the condition of any replacement arthroplasty device have used externally mounted sensors and suffered from the attenuation of acoustic information through flesh and skin. It is hypothesised that the use of directly embedded AE sensors may provide the first steps towards an in-vivo, cost effective, user friendly, non-destructive system capable of continuously monitoring the condition of the implanted construct and locating the earliest incidences of damage initiation

Background: Recently, the new phenomenon of “squeaking” noises emitted from THAs with ceramic-onceramic bearings has spared international interest. It shows a frequency of 0,7–19,5% in literature, but infrequently requires revision surgery. However, an even higher incidence of various other noises from those THAs audible to the human ear have become popular in the process: this noise can resemble clicking, grinding or creaking and can be caused by distinct movements, during longer periods of walking, or can be constant with movement. The incidence of those noises can reach up to 30% of THAs. However, memory has faded that other bearings like metal-on-metal and PE/ceramic have been associated with noises in the past. Therefore we aimed to investigate the occurence of acoustic emissions in patients, who had all received the same implant but with alternate bearings, to investigate the nature of noise, duration and clinical consequence for all 3 bearings (polyethylene/ceramic, metalon-metal, ceramic-on-ceramic). Method: Between 1999–2001, 360 patients were matched in a prospective randomised trial. All of them received a cementless Zimmer© Alloclassic Variall™ implant at the Orthopaedic Hospital Vienna – Speising, Austria with either a ceramic-on-ceramic bearing, a metal-on-metal bearing or a polyethylene/ceramic bearing. A questionnaire was sent via mail, including questions on first occurence of hip noise, information on the kind and duration of the phenomenon and possible adverse evaluation on behalf of the patient. In case of a positive report, the patient was invited to a clinical examination and radiographic analysis. In addition, a specialised audiography was conducted in patients with audible sensations. Finally, the SF-36 and WOMAC were analysed. A number of patients received further examination with methods of gait analysis in order to detect the distinct point of occurence of the noise during the gait cycle. Results: 33 patients reported an audible phenomenon from their THA, 14 received a ceramic-onceramic bearing (Cerasul), 13 a polyethylene/ceramic bearing (Durasul) and 6 a metal-onmetal bearing (Metasul). The most common noise was a distinct clicking, followed by a creaking noise. Only 1 patient reported a squeaking sensation, he received a polyethylene/ceramic bearing. Conclusion: The emission of specific noises from THAs of all bearings has been well documented in recent trials and could be verified in this survey of cementless THAs. No trend towards an increased incidence of noise from THAs with ceramic-on-ceramic bearings could be detected. Interestingly, the single case of „squeaking” was reported from a patient with polyethylene/ceramic bearing. Microseparation and subluxation of the femoral head with resulting edge loading and formation of stripe wear has recently been suspected as the main cause for “noisy hips.” So far 2 ceramic-on-ceramic hips of this study group population have been revised. Both articulations showed areas of stripe wear due to subluxation of the joint

Orthopaedic implants are often fixed into place using bone cement. The degradation of the cement mantle has been implicated as playing a major role in the loosening of these implants, and this often necessitates revision surgery. The present work has used the non-destructive acoustic emission (AE) technique to monitor the initiation and evolution of fatigue damage in bone cement constructs. Using this technique, it should be possible to gain an understanding of failure progression in cemented orthopaedic devices. Previous work in this area has focused on AE activity originating from the eventual failure location in order to identify those signatures associated with critical fatigue cracks. This usually involves analysing AE signatures associated with the final stages of failure; however, there have been limited investigations that have looked at the damage that takes up most of the crack propagation life of the sample, (i.e. microcracking formation and development), that occurs away from the failure site, but could still play a role in final failure. In this study, dog-bone-shaped specimens of bone cement were subjected to uniaxial tensile fatigue loading, with damage monitored along the length of specimens using AE. Where specimens exhibited AE activity at locations away from the fracture site, they were sectioned and subjected to synchrotron tomography, which enabled high resolution images of these regions to be obtained. Microcracks of the order of 20 microns were observed in areas where AE had identified early, non-critical damage; in contrast, no microcracking was observed in areas that either remained unloaded or exhibited no AE. To further corroborate these observations, and characterise the damage mechanisms involved, scanning electron microscopy (SEM) was applied to the sectioned samples. In those locations where significant yet non-critical AE occurred, there was evidence of crack-bridging, suggesting that crack closure mechanisms may have slowed down or even arrested crack propagation within the bone cement. These findings further validate the use of AE as a passive non-destructive method for the identification and understanding of damage evolution in cemented orthopaedic devices

Acoustic emission is an uncommon but well-recognised phenomenon following total-hip arthroplasty using hard-on-hard bearing surfaces. The incidence of squeak has been reported between 1% – 10%. The squeak can be problematic enough to warrant revision surgery. Several theories have been proposed, but the cause of squeak remains unknown. Acoustic analysis shows squeak results from forced vibrations that may come from movement between the liner and shell. A potential cause for this movement is deformation of the shell during insertion. 6 cadaver hemipelvises were prepared to accept ace-tabular components. A shell was selected and pre-insertion the inner shape was measured using a profilometer. The shell was implanted and re-measured. 2x screws were then placed and the shells re-measured. The results were assessed for deformation. Deformation of the shells occurred in 5 of the 6 hemi-pelvises following insertion. The hemipelvis of the non-deformed shell fractured during insertion. Following screw insertion no further shell deformation occurred. The deformation was beyond the acceptable standards of a morse taper which may allow movement between components, and this may produce an acoustic emission. Further in-vitro testing is being conducted to see whether shell deformation allows movement producing an acoustic emission

During conventional hip arthroplasties, the diseased femur is rigidified using a metallic stem. The insertion of the stem induces a change in the stress distribution in the surrounding femur, and the bone remodels; this stress distribution is a direct result of the stem stiffness characteristics. Healthy healing of the femur requires that the bone be loaded as naturally as possible. If the bone is not loaded appropriately, it can resorb which may result in stem loosening and revision. Although current rigid metallic femoral stems are very successful, a poor stress distribution may become a critical problem for younger patients as the stem/femoral bone construct will be subjected to higher loads for longer times, and since remodelling is faster, loosening can occur earlier. Reduced stiffness stems have therefore been investigated, but early failures have been reported due to increased movements, poor initial stability and the low proximal stiffness of the stem. A novel biocompatible carbon fibre reinforced plastic (CFRP) stem has been developed in light of these past experiences. 1. Using a series of analytical models and experimental validation tests. 1. , the fibre type and architecture have been tailored along and across the stem to achieve healthy bone remodelling and proximal strength of the construct. In addition, a biocompatible hydroxyapatite coating was specifically designed to enhance interface strength and stability. 2. The present study describes the mechanical behaviour of this novel stem with particular emphasis on the stem/bone interface. 4 static and 29 fatigue tests were performed according to ISO7206; these tests were complemented by acoustic emission monitoring to identify failure mechanisms. 3. A stress versus number of cycles to failure (SN) curve was obtained to describe the fatigue behaviour (i) under constant amplitude cycling at various load levels and (ii) incorporating rest periods and overloads. In addition, a mechanical test was designed to characterise the motions between the bone and the stem during sinusoidal fatigue loading (5000 cycles, 0.2–2kN, 1Hz). Two linear variable differential transformers measured the vertical and horizontal displacements at the stem/ bone interface in the proximal region. 3 tests were performed on CFRP stems and 3 on a metallic stem. The CFRP stem exceeded the standard requirements. The SN curve showed good repeatability across the loading spectrum. The inclusion of overloads/static loads during fatigue had a beneficial effect on the stem endurance. This is attributed to the development of microcracks, which dissipate the load, and to creep of the resin. The amplitude of recoverable motion observed at the interface during each load cycle was similar for both types of stem (20mm and 4mm in the horizontal and vertical directions respectively) and remained below the recommended limit. 4. Composite materials offer high design flexibility. This has been exploited in the development of a compliant, mechanically tailored biocompatible hip stem for femoral reconstruction, and could provide an answer to hip replacement for younger, more active patients