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Bone & Joint Open
Vol. 5, Issue 7 | Pages 550 - 559
5 Jul 2024
Ronaldson SJ Cook E Mitchell A Fairhurst CM Reed M Martin BC Torgerson DJ

Aims

To assess the cost-effectiveness of a two-layer compression bandage versus a standard wool and crepe bandage following total knee arthroplasty, using patient-level data from the Knee Replacement Bandage Study (KReBS).

Methods

A cost-utility analysis was undertaken alongside KReBS, a pragmatic, two-arm, open label, parallel-group, randomized controlled trial, in terms of the cost per quality-adjusted life year (QALY). Overall, 2,330 participants scheduled for total knee arthroplasty (TKA) were randomized to either a two-layer compression bandage or a standard wool and crepe bandage. Costs were estimated over a 12-month period from the UK NHS perspective, and health outcomes were reported as QALYs based on participants’ EuroQol five-dimesion five-level questionnaire responses. Multiple imputation was used to deal with missing data and sensitivity analyses included a complete case analysis and testing of costing assumptions, with a secondary analysis exploring the inclusion of productivity losses.


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_5 | Pages 40 - 40
1 Apr 2022
Hafez M Nicolaou N Dixon S Obasohan P Giles S Madan S Fernandes J Offiah A
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Introduction. Motorised intramedullary lengthening nails are considered more expensive than external fixators for limb lengthening. This research aims to compare the cost of femoral lengthening in children using the PRECICE magnetic lengthening nail with external fixation. Materials and Methods. Patients: Retrospective analysis of 50 children who underwent femoral lengthening. One group included patients who were treated with PRECICE lengthening nails, the other group included patients who had lengthening with external fixation. Each group included 25 patients aged between 11–17 years. The patients in both groups were matched for age. Cost analysis was performed following micro-costing and analysis of the used resources during the different phases of the treatments. Results. : Each group's mean patient age was 14.7 years. Lengthening nails were associated with longer operative times compared to external fixators, both for implantation and removal surgery (P-value 0.007 and <0.0001 respectively). Length of stay following the implantation surgery, frequency of radiographs, frequency of outpatient department appointments were all more favourable with lengthening nails. The overall cost of lengthening nails was £1393 more than external fixators, although this difference was not statistically significant (P-value 0.088). Conclusions. The cost of femoral lengthening with lengthening nails was not significantly higher than the external fixators’ cost. Further research to review the effectiveness of the devices and the quality of life during the lengthening process is crucial for robust health economic evaluation


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_10 | Pages 104 - 104
1 May 2016
Petis S Howard J Lanting B Marsh J Vasarhelyi E
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Introduction. Total hip arthroplasty (THA) is a commonly performed surgical procedure for the treatment of hip arthritis. Approximately 50,000 THAs are performed annually in Canada. The costs incurred to the healthcare system are tremendous, amounting to anywhere between 4.3 and 7.3 billion dollars each year. Despite the substantial financial burden of THA to the Canadian healthcare system, few studies have provided accurate cost estimations of this procedure. Purpose. To determine the impact of surgical approach on costs of THA from a hospital perspective, and provide an updated cost estimation of THA within a publically funded healthcare system. Methods. We recruited patients undergoing a THA through an anterior, posterior, or lateral approach for study participation. A single surgeon was designated to perform every case using the surgical approach of their expertise. Each patient received standardized implants: a collared, hydroxyapatite-coated, cementless femoral stem (Corail TM stem, DePuy Orthopaedics Inc., Warsaw, IN), a cementless acetabular cup (Pinnacle Sector II TM acetabular cup, DePuy Orthopaedics Inc., Warsaw, IN), a highly cross-linked polyethylene liner (AltrX TM polyethylene liner, DePuy Orthopaedics Inc., Warsaw, IN), and a cobalt chrome femoral head (Articul/eze TMcobalt chrome, DePuy Orthopaedics Inc., Warsaw, IN). We prospectively recorded costs of operating room time, length of stay in hospital, and medical and surgical interventions using a micro-costing method. Group comparisons were performed using Pearson's Chi-square and one-way Analysis of Variance (ANOVA), with post-hoc testing when necessary. All costs were reported in 2013 Canadian dollars. Results. One-hundred and eighteen patients (40 anterior, 38 posterior, and 40 lateral) completed the study. All three groups were similar with regards to age (p=0.79), sex (p=0.97), and body mass index (p=0.54). Mean operating room time was significantly shorter for the lateral (49.0 minutes, 95%CI 46.5 – 51.5) versus anterior (69.3 minutes, 95%CI 66.0 – 72.6, p<0.001) and posterior approach (61.6 minutes, 95%CI 57.5 – 65.5, p<0.001). Mean length of stay was shorter for the anterior (33.9 hours, 95%CI 29.6 – 38.2) compared to the posterior (65.8 hours, 95%CI 56.8 – 74.8, p<0.001) and lateral approach (64.2 hours, 95%CI 56.7 – 71.7, p<0.001). The operating room costs were significantly higher for the anterior versus posterior (p=0.008) and lateral approach (p<0.001, figure 1). The total inpatient costs were significantly for the anterior versus posterior and lateral approach (p<0.001 for both pair-wise comparisons, figure 2). Total costs were significantly less for the anterior ($7300.22, 95%CI 7064.49 – 7535.95) versus posterior ($8287.46, 95%CI 7906.41 – 8668.51, p<0.001) and lateral approach ($7853.10, 95%CI 7577.29 – 8128.91, p=0.031). Discussion / Conclusion. Total costs for THA were significantly less when performed using an anterior approach. A reduction in hospital length of stay contributed significantly to an overall reduction in costs from a hospital perspective. Future analyses will determine the cost-effectiveness of the anterior approach from both a hospital and societal perspective


The Bone & Joint Journal
Vol. 98-B, Issue 2 | Pages 152 - 159
1 Feb 2016
Corbacho B Duarte A Keding A Handoll H Chuang LH Torgerson D Brealey S Jefferson L Hewitt C Rangan A

Aims

A pragmatic multicentre randomised controlled trial (PROFHER) was conducted in United Kingdom National Health Service (NHS) hospitals to evaluate the clinical effectiveness and cost effectiveness of surgery compared with non-surgical treatment for displaced fractures of the proximal humerus involving the surgical neck in adults.

Methods

A cost utility analysis from the NHS perspective was performed. Differences between surgical and non-surgical treatment groups in costs and quality adjusted life years (QALYs) at two years were used to derive an estimate of the cost effectiveness of surgery using regression methods.


The Bone & Joint Journal
Vol. 98-B, Issue 2 | Pages 249 - 259
1 Feb 2016
Sabharwal S Carter AW Rashid A Darzi A Reilly P Gupte CM

Aims

The aims of this study were to estimate the cost of surgical treatment of fractures of the proximal humerus using a micro-costing methodology, contrast this cost with the national reimbursement tariff and establish the major determinants of cost.

Methods

A detailed inpatient treatment pathway was constructed using semi-structured interviews with 32 members of hospital staff. Its content validity was established through a Delphi panel evaluation. Costs were calculated using time-driven activity-based costing (TDABC) and sensitivity analysis was performed to evaluate the determinants of cost


The Bone & Joint Journal
Vol. 97-B, Issue 9 | Pages 1264 - 1270
1 Sep 2015
Karantana A Scammell BE Davis TRC Whynes DK

This study compares the cost-effectiveness of treating dorsally displaced distal radial fractures with a volar locking plate and percutaneous fixation. It was performed from the perspective of the National Health Service (NHS) using data from a single-centre randomised controlled trial. In total 130 patients (18 to 73 years of age) with a dorsally displaced distal radial fracture were randomised to treatment with either a volar locking plate (n = 66) or percutaneous fixation (n = 64). The methodology was according to National Institute for Health and Care Excellence guidance for technology appraisals. .

There were no significant differences in quality of life scores between groups at any time point in the study. Both groups returned to baseline one year post-operatively.

NHS costs for the plate group were significantly higher (p < 0.001, 95% confidence interval 497 to 930). For an additional £713, fixation with a volar locking plate offered 0.0178 additional quality-adjusted life years in the year after surgery. The incremental cost-effectiveness ratio (ICER) for plate fixation relative to percutaneous fixation at list price was £40 068. When adjusting the prices of the implants for a 20% hospital discount, the ICER was £31 898. Patients who underwent plate fixation did not return to work earlier.

We found no evidence to support the cost-effectiveness, from the perspective of the NHS, of fixation using a volar locking plate over percutaneous fixation for the operative treatment of a dorsally displaced radial fracture.

Cite this article: Bone Joint J 2015;97-B:1264–70.


The Bone & Joint Journal
Vol. 97-B, Issue 8 | Pages 1082 - 1089
1 Aug 2015
Tubeuf S Yu G Achten J Parsons NR Rangan A Lamb SE Costa ML

We present an economic evaluation using data from the Distal Radius Acute Fracture Fixation Trial (DRAFFT) to compare the relative cost effectiveness of percutaneous Kirschner wire (K-wire) fixation and volar locking-plate fixation for patients with dorsally-displaced fractures of the distal radius.

The cost effectiveness analysis (cost per quality-adjusted life year; QALY) was derived from a multi-centre, two-arm, parallel group, assessor-blind, randomised controlled trial which took place in 18 trauma centres in the United Kingdom. Data from 460 patients were available for analysis, which includes both a National Health Service cost perspective including costs of surgery, implants and healthcare resource use over a 12-month period after surgery, and a societal perspective, which includes the cost of time off work and the need for additional private care.

There was only a small difference in QALYs gained for patients treated with locking-plate fixation over those treated with K-wires. At a mean additional cost of £714 (95% confidence interval 588 to 865) per patient, locking-plate fixation presented an incremental cost effectiveness ratio (ICER) of £89 322 per QALY within the first 12 months of treatment. Sensitivity analyses were undertaken to assess the ICER of locking-plate fixation compared with K-wires. These were greater than £30 000.

Compared with locking-plate fixation, K-wire fixation is a ‘cost saving’ intervention, with similar health benefits.

Cite this article: Bone Joint J 2015;97-B:1082–9.