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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_III | Pages 64 - 64
1 Feb 2012
Forward D Singh A Lawrence T Sithole J Davis T Oni J
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Background. It was hypothesised that preserving a layer of gliding tissue, the parietal layer of the ulnar bursa, between the contents of the carpal tunnel and the soft tissues incised during carpal tunnel surgery might reduce scar pain and improve grip strength and function following open carpal tunnel decompression. Methods. Patients consented to randomisation to treatment with either preservation of the parietal layer of the ulnar bursa beneath the flexor retinaculum at the time of open carpal tunnel decompression (57 patients) or division of this gliding layer as part of a standard open carpal tunnel decompression (61 patients). Grip strength was measured, scar pain was rated and the validated Patient Evaluation Measure questionnaire was used to assess symptoms and disability pre-operatively and at eight to nine weeks following surgery in seventy-seven women and thirty-four men; the remaining seven patients were lost to follow-up. Results. There was no difference between the groups with respect to age, sex, hand dominance or side of surgery. Grip strength, scar pain and Patient Evaluation Measure score were not significantly different between the two groups, although there was a trend towards poorer subjective outcome as demonstrated by the questionnaire in the group in which the ulnar bursa within the carpal tunnel had been preserved. Preserving the ulnar bursa within the carpal tunnel did however result in a lower prevalence of suspected wound infection or inflammation (p=0.04). Conclusions. In this group of patients, preservation of the ulnar bursa around the median nerve during open carpal tunnel release produced no significant difference in grip strength or self-rated symptoms. We recommend incision of the ulnar bursa during open carpal tunnel decompression to allow complete visualisation of the median nerve and carpal tunnel contents


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIII | Pages 52 - 52
1 May 2012
Wyatt M Gwynne-Jones D Veale G
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Introduction/aims. Carpal tunnel decompression is common at the world's largest lamb processing plant. The purpose of this study was to establish whether lamb boning caused carpal tunnel syndrome, whether expeditious rehabilitation was possible and current New Zealand Orthopaedic practice. Method. The incidences/relative risks of carpal tunnel syndrome were calculated. Kaplan-Meier survival analysis was performed examining six seasons. Comparison with a standard idiopathic population was performed. Retrospective review of five seasons established rate of return to work/complications using an accelerated rehabilitation programme. A prospective study qualified pre/postoperative symptoms using validated techniques. An email survey of the NZOA was also performed. Medical statistician advice was provided throughout. Results. Median five-year survival for a lamb boner's carpal tunnel was 44%; boners were 120% more likely to need decompression than non-knife hands (p<0.01). The incidence of carpal tunnel syndrome in lamb boners was 10% (person-seasons): twice that of non-knife hands. This population is entirely different to the published idiopathic population (female, mean age 55). In both retrospective and prospective cohorts, postoperative return to work was 28 days: more rapid than NZOA practice. Rapid return did not cause further absenteeism nor high complication rates. There were no failed decompressions. Conclusions. This study provides good evidence that carpal tunnel syndrome can be occupational. Our unique population has allowed a culture to develop whereby early postoperative return to is expected. This culture, good patient education and coordinated efforts at all levels of the care pathway is necessary for this level of achievement. Declaration. In relation to the conduct of this study, no funding has been received from any source to support the cost of this study


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_III | Pages 51 - 51
1 Feb 2012
Johnston P Chojnowski A Davidson R Riley G Donell S Clark I
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The purpose of this study was to profile the mRNA expression for the 23 known matrix metalloproteinases (MMPs), 4 tissue inhibitor of metalloproteinases (TIMPs) and 19 ADAMTSs (a disintegrin and metalloproteinase with thrombospontin motif) in Dupuytren's Disease and normal palmar fascia. Dupuytren's Disease (DD) is a fibroproliferative disorder affecting the palmar fascia, leading to contractures. The MMPs and ADAMTSs are related enzymes collectively responsible for turnover of the extracellular matrix. The balance between the proteolytic action of the MMPs and ADAMTSs and their inhibition by the TIMPs underpins many pathological processes. Deviation in favour of proteolysis is seen in e.g. invasive carcinomata, whereas an imbalance towards inhibition causes e.g. fibrosis. A group of patients with end-stage gastric carcinoma was treated with a broad spectrum MMP inhibitor in an attempt to reduce the rate of carcinoma advancement; a proportion developed a ‘musculoskeletal syndrome’ resembling DD. Tissue samples were obtained from patients undergoing surgery to correct contractures caused by DD and from healthy controls undergoing carpal tunnel decompression. The DD tissue was separated macroscopically into cord and nodule. Total RNA was extracted and mRNA expression analysed by quantitative real-time reverse transcriptase polymerase chain reaction (qRT-PCR), normalised to 18S rRNA. Comparing across all genes, the DD nodule, DD cord and normal palmar fascia samples each had a distinct mRNA expression profile. Statistically significant (p<0.05) differences in mRNA expression included: higher MMP-2, -7 and ADAMTS-3 levels in both cord and nodule; higher MMP-1, -14, TIMP-1 and ADAMTS-4 and -5 in nodule alone, lower MMP-3 in nodule and cord and lower TIMP-2, -3 and -4 and ADAMTS-1 and -8 levels in nodule alone. The distinct mRNA profile of each group suggests differences in extracellular proteolytic activity which may underlie the process of fascial remodelling in DD


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 223 - 223
1 Sep 2012
Bowey A Athanatos L Bhalaik V
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Introduction. Cubital Tunnel syndrome is common affecting 1 in 4000 people. The cubital tunnel serves as major constraint for the ulna nerve. Cubital tunnel decompression is a relatively simple operation to resolve the patients' symptoms. There has been published data on return to work and normal activity after carpal tunnel decompression but not cubital tunnel. Method. All patients who underwent cubital tunnel decompression in Wirral University Teaching Hospital NHS Foundation Trust between September 2006 and September 2010 were identified and sent a questionnaire; enquiring about age, type of job & if it involved heavy lifting, time off work, range of movement at elbow and hand and if their symptoms resolved or if they had any other complications. Results. 106 cubital tunnels were decompressed in the 4 year period. 66 patients returned the questionnaire (62% response). The average age at operation was 59 years (32–86years). The average time to return to work after surgery was 10 days (0–300days). Complications included painful scar, return of symptoms and chronic region pain syndrome, which lead the patient to change jobs (300days). Only one patient was self-employed, they had no time off work. In 24 patients (36%) their symptoms either never resolved or returned, only worsening in 2 patientsstopping them returning to work their heavy manual jobs. The DASH score (work modules) post operatively was 38.3 over all working groups; this was lower in patients who didn't have a manual job. Conclusion. Our patients, returned to work at around 10 days after surgery. People with jobs which involved no heavy lifting returned at 5 days compared to that of 40 days, in patients with manual jobs. Now we can give our patients more accurate information about how long it will take them to return to work, depending on their job type


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XLI | Pages 77 - 77
1 Sep 2012
English J Gwynne-Jones D Taylor P
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Carpal tunnel syndrome (CTS) is said to be a condition of middle-aged women. Our experience is that it more commonly occurs in older people and also in a younger working population. The aim of this study is to describe the epidemiology of CTS requiring carpal tunnel decompression (CTD). Over a 10.5 year period 3073 CTD were performed on 2309 patients aged 15 – 93 years. This included all public, private and ACC funded cases in our region. During this period we had no restriction to access to CTD as all publicly funded cases were performed under local anaesthetic in a day surgery unit. Neurophysiological studies were performed pre-operatively by the same neurophysiologist. Population data from the national census (2006) was used to calculate the annual incidence of patients requiring CTD for each 5 year age band. There were 1418 females (61.4%) and 891 males (38.6 %). In contrast females comprised 116 of 306 (37.8%) patients who had their surgery funded by ACC. The mean age at surgery was 45 years for ACC cases compared with 56 years for non-ACC funded cases. The incidence of males having surgery funded by ACC was 1.7 times higher than females. There was a biphasic pattern in females with an incidence of 3.0/1000 at age 50–54 years, and a second higher peak of 3.1 to 3.4/1000 from 70 to 5 years. Males had a linear increase in incidence peaking at 3.1/1000 for age 65–69 years declining slightly to 2.8/1000 for age 70–85 years. The incidence was significantly higher in females than males overall (1.8 v 1.1/1000) and in patients under 65 years (1.4 v 0.8/1000). In patients over 65 years there was no significant difference in incidence (female 2.8, male 2.5/1000). Within our region, the incidence of surgically treated carpal tunnel syndrome increases with age. The highest rates are seen over the age of 70 in women and 65 years in men with no significant difference in rates between men or women over 65 years


Bone & Joint Open
Vol. 1, Issue 8 | Pages 450 - 456
1 Aug 2020
Zahra W Dixon JW Mirtorabi N Rolton DJ Tayton ER Hale PC Fisher WJ Barnes RJ Tunstill SA Iyer S Pollard TCB

Aims

To evaluate safety outcomes and patient satisfaction of the re-introduction of elective orthopaedic surgery on ‘green’ (non-COVID-19) sites during the COVID-19 pandemic.

Methods

A strategy consisting of phased relaxation of clinical comorbidity criteria was developed. Patients from the orthopaedic waiting list were selected according to these criteria and observed recommended preoperative isolation protocols. Surgery was performed at green sites (two local private hospitals) under the COVID-19 NHS contract. The first 100 consecutive patients that met the Phase 1 criteria and underwent surgery were included. In hospital and postoperative complications with specific enquiry as to development of COVID-19 symptoms or need and outcome for COVID-19 testing at 14 days and six weeks was recorded. Patient satisfaction was surveyed at 14 days postoperatively.