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Bone & Joint Open
Vol. 4, Issue 11 | Pages 839 - 845
6 Nov 2023
Callary SA Sharma DK D’Apollonio TM Campbell DG

Aims. Radiostereometric analysis (RSA) is the most accurate radiological method to measure in vivo wear of highly cross-linked polyethylene (XLPE) acetabular components. We have previously reported very low wear rates for a sequentially irradiated and annealed X3 XLPE liner (Stryker Orthopaedics, USA) when used in conjunction with a 32 mm femoral heads at ten-year follow-up. Only two studies have reported the long-term wear rate of X3 liners used in conjunction with larger heads using plain radiographs which have poor sensitivity. The aim of this study was to measure the ten-year wear of thin X3 XLPE liners against larger 36 or 40 mm articulations with RSA. Methods. We prospectively reviewed 19 patients who underwent primary cementless THA with the XLPE acetabular liner (X3) and a 36 or 40 mm femoral head with a resultant liner thickness of at least 5.8 mm. RSA radiographs at one week, six months, and one, two, five, and ten years postoperatively and femoral head penetration within the acetabular component were measured with UmRSA software. Of the initial 19 patients, 12 were available at the ten-year time point. Results. The median proximal, 2D, and 3D wear rates calculated between one and ten years were all less than 0.005 mm/year, with no patient recording a proximal wear rate of more than 0.021 mm/year. Importantly, there was no increase in the wear rate between five and ten years. Conclusion. The very low wear rate of X3 XLPE liners with larger articulations remains encouraging for the future clinical performance of this material. Cite this article: Bone Jt Open 2023;4(11):839–845


The Bone & Joint Journal
Vol. 98-B, Issue 12 | Pages 1604 - 1610
1 Dec 2016
Callary SA Field JR Campbell DG

Aims. The increased in vivo resistance to wear of highly crosslinked polyethylene (HXLPE) in total hip arthroplasty (THA) has led to an increased use of larger articulations which have been shown to reduce the incidence of early dislocation. To date, there are few reports of the wear of larger articulations using second generation HXLPE liners. Our prospective cohort study measured the bedding-in and early wear of large (36 mm and 40 mm diameter) articulations involving a second generation X3 HXLPE liner and compared our findings with previous clinical and in vitro studies of the same material. Patients and Methods. The proximal penetration of the femoral head five years post-operatively was measured for 15 patients using radiostereometric analysis (RSA). Results. The median proximal bedding-in within the first post-operative year was 0.022 mm (interquartile range (IQR) -0.050 to 0.091). The median proximal rate of wear between one and five years was -0.004 mm/year (IQR -0.021 to 0.022). The rates of proximal, medial, 2D or 3D wear between one and five years post-operatively of the X3 HXLPE liner did not increase with larger articulations compared with our previous study of 32 mm articulations. Conclusion. Although reassuring, the use of larger articulations requires continued monitoring to determine whether the low wear observed in the short-term continues to the mid- to long-term. Cite this article: Bone Joint J 2016;98-B:1604–10


The Bone & Joint Journal
Vol. 102-B, Issue 7 | Pages 811 - 821
1 Jul 2020
You D Sepehri A Kooner S Krzyzaniak H Johal H Duffy P Schneider P Powell J

Aims. Dislocation is the most common indication for further surgery following total hip arthroplasty (THA) when undertaken in patients with a femoral neck fracture. This study aimed to assess the complication rates of THA with dual mobility components (THA-DMC) following a femoral neck fracture and to compare outcomes between THA-DMC, conventional THA, and hemiarthroplasty (HA). Methods. We performed a systematic review of all English language articles on THA-DMC published between 2010 and 2019 in the MEDLINE, EMBASE, and Cochrane databases. After the application of rigorous inclusion and exclusion criteria, 23 studies dealing with patients who underwent treatment for a femoral neck fracture using THA-DMC were analyzed for the rate of dislocation. Secondary outcomes included reoperation, periprosthetic fracture, infection, mortality, and functional outcome. The review included 7,189 patients with a mean age of 77.8 years (66.4 to 87.6) and a mean follow-up of 30.9 months (9.0 to 68.0). Results. THA-DMC was associated with a significantly lower dislocation rate compared with both THA (OR 0.26; 95% CI 0.08 to 0.79) and HA (odds ratio (OR) 0.27; 95% confidence interval (CI) 0.15 to 0.50). The rate of large articulations and of intraprosthetic dislocation was 1.5% (n = 105) and 0.04% (n = 3) respectively. Conclusion. THA-DMC when used in patients with a femoral neck fracture is associated with a lower dislocation rate compared with conventional arthroplasty options. There was no increase in the rates of other complication when THA-DMC was used. Future cost analysis and prospective, comparative studies are required to assess the potential benefit of using THA-DMC in these patients. Cite this article: Bone Joint J 2020;102-B(7):811–821


Abstract. Objectives. Hip instability following total hip arthroplasty in treatment of intracapsular neck of femur fractures is reported at 8–11%. Utilising the principle of a small articulation to minimize the problems of wear coupled with a large articulation, dual-mobility total hip arthroplasty prostheses stabilise the hip further than conventional fixed-bearing designs. The aim of this study is to compare the rate of dislocation and complication between standard fixed-bearing and dual-mobility prostheses for the treatment of intracapsular neck of femur fractures. Methods. A four-year retrospective review in a large district general hospital was completed. All cases of intracapsular neck of femur fractures treated with total hip arthroplasty were identified through the theatre logbooks. Patient's operative and clinical notes were retrospectively reviewed to collect data. Results. A total of 91 patients underwent total hip arthroplasty for intracapsular neck of femur fracture in the four-year period. 61.5% were dual-mobility design versus 28.5% had fixed-bearing implants. There were no statistical differences between patient group characteristics. Choice of implant was dependent on surgeon preference. There was a 0.0% dislocation rate in the dual-mobility group versus 8.6% in the fixed-bearing prosthesis group. All dislocations occurred in patients who underwent total hip arthroplasty with 36.0mm fixed-bearing prosthesis via posterior surgical approach. There was no statistical difference in mortality between both groups. Conclusion. There was an increasing trend of towards the use of dual-mobility prosthesis for fractured neck of femur within this department with excellent outcomes. Dual-mobility designs provide reduced dislocation rates in total hip arthroplasty in intracapsular neck of femur fractures compared to standard fixed-bearing designs at this institution. The authors recommend that all orthopaedic staff consider the use of dual-mobility prostheses in suitable patients and ensure trainees are suitably trained in use of dual-mobility designs. Declaration of Interest. (b) declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported:I declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project


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Large articulations are increasingly being used to reduce dislocation, the most common early complication following THR. However, potential benefits of large articulations in reducing dislocation have not been proven in a well-controlled clinical trial. The aim of our randomised controlled trial was to compare the one-year incidence of dislocation between 36 and 28 mm metal on highly cross-linked polyethylene articulations. Patients were excluded if they had a high risk of dislocation due to, for example, abnormal anatomy, neuromuscular disease, previous infection or dislocation. Eligible patients were stratified according to a number of other factors which may influence dislocation risk, including primary or revision THR and, if primary THR, by surgeon, age, diagnosis, sex and Charnley grade. Patients were randomised intra- operatively to either a 28 or 36 mm articulation. Dislocation incidence was determined using a hip instability questionnaire and a hospital visit questionnaire. A dislocation was diagnosed if there was radiological evidence and reduction by a doctor was required. Six-hundred-and-forty-four patients undergoing primary or revision THR were entered into the study. Overall, the incidence of dislocation at one year following THR was 5.4% with a 28 mm articulation and 1.3% with a 36 mm articulation (p=.004). Incidence in primary THR patients was 4.4% with a 28 mm articulation, compared to 0.8% with a 36 mm articulation (p=.007). Incidence in revision THR patients was 12.2% and 4.9% with 28 and 36 mm articulations, respectively. For both primary and revision THR patients, sex distribution, age and BMI of patients who dislocated were similar to those of the total samples of primary or revision patients. This large randomised study unequivocally shows for the first time that, compared to a 28 mm articulation, a 36 mm articulation in THR is efficacious in reducing the incidence of dislocation in the first year following THR


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 518 - 518
1 Oct 2010
Holubowycz O Howie D Middleton R
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Large articulations using cross-linked polyethylene and other alternate bearings are increasingly being used to reduce the incidence of dislocation, the most common early complication following total hip replacement. While indirect evidence has suggested the potential benefits of a large articulation in reducing dislocation risk, this has not been proven in a well-controlled clinical trial. The primary objective of our multi-centre international randomized controlled trial was to compare the one-year incidence of dislocation between a 36 mm and 28 mm metal on highly cross-linked polyethylene articulation in primary and revision total hip replacement. 644 patients were entered into the study. Patients were stratified according to a number of factors which may influence dislocation risk, including primary or revision total hip replacement, age, sex, Charnley grade, diagnosis and stem type. Patients were randomized intra-operatively to either a 28 or 36 mm articulation. The 12-month incidence of dislocation was statistically significantly lower in patients undergoing total hip replacement with a 36 mm articulation than in those with a 28 mm articulation (1.3% vs 5.2%, p< .05). A total of 6 dislocations occurred in the 4 patients who dislocated with a 36 mm articulation, compared to a total of 36 dislocations in the 17 patients who dislocated with a 28 mm articulation. When primary and revision THR were examined separately, the 12-month incidence of dislocation was statistically significantly lower in patients undergoing primary total hip replacement with a 36 mm articulation than in those with a 28 mm articulation (0.7% vs 4.2%, p< .05). A total of 4 dislocations occurred in two patients with a 36 mm articulation, compared to a total of 19 dislocations in 12 patients with a 28 mm articulation. The incidence of dislocation after revision total hip replacement with a 36 mm articulation was 4.8%, compared to 11.1% with a 28 mm articulation. This large randomized study unequivocally shows for the first time that, compared to a 28 mm articulation, a 36 mm articulation in total hip replacement is efficacious in reducing the incidence of dislocation in the first year following hip replacement


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 518 - 518
1 Oct 2010
Holubowycz O Howie D Middleton R
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Early revision is an important risk factor for repeated revision and poor results after primary total hip replacement and instability is a major cause of early revision. Larger articulations with cross-linked polyethylene are proposed as a solution, but these are not without risk, including fracture of the thin polyethylene rim of the liner. The aim of our study was to examine implant-related revisions among primary total hip replacement patients with up to six year follow-up in a randomized controlled trial which compared 28 mm and 36 mm metal on highly cross-linked polyethylene articulations in total hip replacement. 557 patients undergoing primary total hip replacement were included in this study. Risk factors for dislocation and wear were controlled by stratification and patients were then randomized intra-operatively to either a 28 or 36 mm articulation. To date, 10 hips have been revised for implant-related problems following primary total hip replacement. Seven hips with a 28 mm articulation were revised to a larger articulation because of instability. Four of these were for recurrent dislocation, one for an irreduceable first dislocation and two for subluxation. In contrast, only one patient who had undergone total hip replacement with a 36 mm articulation was revised for recurrent dislocation. One hip with a 36 mm articulation in a well-positioned cup was revised to a 32 mm articulation because of elevated lip liner fracture. Another 36 mm articulation hip was revised for acetabular component loosening. This study shows that a 36 mm metal on highly cross-linked polyethylene articulation reduces the need for early revision for instability after primary total hip replacement. However, these benefits need to be weighed against the potential risks associated with these articulations, including rare fracture of the relatively thin poly-ethylene liner


The Bone & Joint Journal
Vol. 106-B, Issue 5 Supple B | Pages 98 - 104
1 May 2024
Mallett KE Guarin Perez SF Taunton MJ Sierra RJ

Aims

Dual-mobility (DM) components are increasingly used to prevent and treat dislocation after total hip arthroplasty (THA). Intraprosthetic dissociation (IPD) is a rare complication of DM that is believed to have decreased with contemporary implants. This study aimed to report incidence, treatment, and outcomes of contemporary DM IPD.

Methods

A total of 1,453 DM components were implanted at a single academic institution between January 2010 and December 2021: 695 in primary and 758 in revision THA. Of these, 49 presented with a dislocation of the large DM head and five presented with an IPD. At the time of closed reduction of the large DM dislocation, six additional IPDs occurred. The mean age was 64 years (SD 9.6), 54.5% were female (n = 6), and mean follow-up was 4.2 years (SD 1.8). Of the 11 IPDs, seven had a history of instability, five had abductor insufficiency, four had prior lumbar fusion, and two were conversions for failed fracture management.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_10 | Pages 13 - 13
1 Jun 2018
Sculco T
Full Access

The selection of an acetabular component for primary hip arthroplasty has narrowed significantly over the past 10 years. Although monoblock components demonstrated excellent long-term success the difficulty with insertion and failure to fully appreciate full coaptation of contact with the acetabular floor has led to almost complete elimination of its utilization. Modular acetabular components usually with titanium shells and highly crosslinked polyethylene are by far the most utilised today. This is particularly true with mid-term results demonstrating excellent wear rates and extremely low failure rates and the concern of possible mechanical failure of highly crosslinked polyethylene not being a clinical problem. Ceramic liners are also used but problems with squeaking articulations and liner chipping have made highly crosslinked polyethylene the preferred liner material. Metal-on-metal except in surface replacement arthroplasty is rarely used in primary hip arthroplasty. With instability in total hip replacement still being a significant and the leading cause of revision hip replacement the dual mobility articulation has emerged as an increasingly used acetabular component. This is composed of either a monoblock cobalt chrome socket articulating with a large polyethylene liner into which the femoral head is constrained. The polyethylene liner becomes essentially a larger femoral head articulation and hip stability is significantly improved. A modular dual mobility can also be utilised with a titanium shell and a cobalt chrome liner inserted into the shell and then a dual mobility articulation. In a recent series of 182 dual mobility cups, all monoblock ADM, in high risk patients undergoing primary total hip replacement there was 1 interprosthetic dislocation which occurred during reduction of a dislocation. Average follow up was 4.4 years with a range of 2–6.6 years


The Bone & Joint Journal
Vol. 103-B, Issue 10 | Pages 1633 - 1640
1 Oct 2021
Lex JR Evans S Parry MC Jeys L Stevenson JD

Aims

Proximal femoral endoprosthetic replacements (PFEPRs) are the most common reconstruction option for osseous defects following primary and metastatic tumour resection. This study aimed to compare the rate of implant failure between PFEPRs with monopolar and bipolar hemiarthroplasties and acetabular arthroplasties, and determine the optimum articulation for revision PFEPRs.

Methods

This is a retrospective review of 233 patients who underwent PFEPR. The mean age was 54.7 years (SD 18.2), and 99 (42.5%) were male. There were 90 patients with primary bone tumours (38.6%), 122 with metastatic bone disease (52.4%), and 21 with haematological malignancy (9.0%). A total of 128 patients had monopolar (54.9%), 74 had bipolar hemiarthroplasty heads (31.8%), and 31 underwent acetabular arthroplasty (13.3%).


The Bone & Joint Journal
Vol. 103-B, Issue 5 | Pages 872 - 880
1 May 2021
Young PS Macarico DT Silverwood RK Farhan-Alanie OM Mohammed A Periasamy K Nicol A Meek RMD

Aims

Uncemented metal acetabular components show good osseointegration, but material stiffness causes stress shielding and retroacetabular bone loss. Cemented monoblock polyethylene components load more physiologically; however, the cement bone interface can suffer fibrous encapsulation and loosening. It was hypothesized that an uncemented titanium-sintered monoblock polyethylene component may offer the optimum combination of osseointegration and anatomical loading.

Methods

A total of 38 patients were prospectively enrolled and received an uncemented monoblock polyethylene acetabular (pressfit) component. This single cohort was then retrospectively compared with previously reported randomized cohorts of cemented monoblock (cemented) and trabecular metal (trabecular) acetabular implants. The primary outcome measure was periprosthetic bone density using dual-energy x-ray absorptiometry over two years. Secondary outcomes included radiological and clinical analysis.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XL | Pages 42 - 42
1 Sep 2012
De Smet K
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Surface arthroplasty or resurfacing represents a significant development in the evolution of hip replacement. A hip resurfacing arthroplasty (HRA) is a bone conserving alternative to total hip arthroplasty (THA) that restores normal joint biomechanics and load transfer and ensures joint stability. Metal-on-metal (MoM) bearings have been preferred for these large diameter articulations because of their lower volumetric wear and smaller particulate debris compared to metal-on-poly-ethylene bearings. Of the many engineering factors which have contributed to the success of the MoM bearing, the metallurgy, diametral clearance, sphericity and surface finish were thought to be most important. More recently, adverse reactions to metal particles and ions generated by wear and corrosion of the metal surfaces have focused the attention on the importance of coverage angle and cup positioning. Currently, the scientific consensus is that cup coverage angle, diametral clearance and metallurgy have their importance in that order. Precise understanding of manufacturing variables is imperative in obtaining clinical consistency and safety in the patient. It is important to examine femoral fixation, bone remodelling, and wear of MoM implants. For the second and third generation MoM HRA various designs and biomaterials have been used. We have conducted a randomised, controlled trial comparing 9 different hip resurfacing prostheses. Clinical and radiographic outcome and whole blood, serum and urine metal ion levels are evaluated at 6 months, 1 year and 2 years in 180 patients with 9 different HRA designs and the differences are analyzed. Besides, the design quality of the 9 different metal-on-metal prostheses and their accessory instruments have been judged during the operation. The Durom with its Metasul history may claim a metallurgic advantage, and in combination with the highest coverage angle of all cups, it may be the best wear couple, as suggested by low ion measurements. However, as discussed above, an optimal bearing alone is not sufficient to achieve a successful hip resurfacing


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_34 | Pages 412 - 412
1 Dec 2013
Garofolo G Snir N Park B Wolfson T Hamula M Levin N Marwin S
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Background:. Dual mobility components in total hip arthroplasty have been successfully in use in Europe for greater than 25 years. However, these implants have only recently obtained FDA approval and acceptance among North American arthroplasty surgeons. Both decreased dislocation rate and decreased wear rates have been proposed benefits of dual mobility components. These components have been used for primary total hip arthroplasty in patients at high risk for dislocation, total hip arthroplasty in the setting of femoral neck fracture, revision for hip instability, and revision for large metal-on-metal (MoM) hip articulation. The literature for the North American experience is lacking. Purpose:. We report indications, short term outcomes, and complications of a series of subjects who received dual mobility outcomes at one institution. Study Design:. Consecutive subjects who received dual mobility total hip arthroplasty components from February 2010 and April 2013 were identified. Charts were retrospectively reviewed for surgical indications, comorbidities, component sizes, and perioperative complications including infection, dislocation, mechanical failure, and reoperation. Results:. 86 hips in 83 subjects underwent total hip arthroplasty or revision total hip arthroplasty using dual mobility components. There were 56 primary total hips and 30 revision total hips. Indications included small acetabular components in the setting of AVN (13 hips), DDH (12 hips) or severe inflammatory arthritis (5 hips), femoral neck fracture (5 hips), intraoperative instability (6 hips), recurrent postoperative instability (5 hips), and revision of large MoM articulations in the setting of failed hip resurfacing (10 hips) or failed MoM total hip arthroplasty (6 hips). Mean follow up was 1 year (3 months to 3.3 years). There were no complications in the primary total hip group. In the revision total hip group, only one hip dislocated and this was in a patient with familial dysautonomia and insensitivity to pain. One subject underwent reoperation for acute prosthetic joint infection. No other complications were encountered. Overall dislocation rate was 1.1% and overall complication rate was 2.2%. Conclusions:. These results closely mirror that of the European literature. Dual mobility articulations in total hip arthroplasty have a low short term complication rate in this cohort and provide a simple solution to difficult cases. Indications for these implants include primary and revision total hip arthroplasty in patients at high risk for instability and revision of large MoM implants including hip resurfacing


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 523 - 523
1 Oct 2010
Kwon Y Athanasou N Gill H Gundle R Mclardy-Smith P Murray D Ostlere S Whitwell D
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Tribological studies of hip arthroplasty suggest that larger diameter metal-on-metal (MOM) articulations would produce less wear than smaller diameter articulations. Other advantages using these large femoral heads implants include better stability with lower dislocation rates and improved range of motion. The aim of the present study was to compare chromium (Cr), cobalt (Co) and titanium (Ti) ion concentrations up to 1-year after implantation of different large diameter MOM total hip arthroplasty (THA). Methods: Cr, Co and Ti concentrations were measured using a high resolution mass spectrometer (HR-ICP-MS) by an independent laboratory in 110 patients, randomized to receive a large metal-on-metal articulation unce-mented Ti THA from one of the following companies: Zimmer, Smith & Nephew, Biomet or Depuy. Samples of whole blood were collected pre-operatively, and postoperatively at six months and one year. Summary of Results: At 6 months, whole blood cobalt levels were: (table removed). Statistical group comparison revealed significant difference for Cr (p=0.006), Co (p=0.047) and Ti (p=< 0.001). With Biomet implants presenting the best results for Cr and Co and Zimmer the highest Ti level. Discussion: Different implant factors may influence measured metal ion level in whole blood: articular surface wear and implant passive corrosion. Bearing wear may be related to its diameter, quality of the surface finish, component sphericity, radial clearance, manufacturing process (forged vs cast metal) and metal carbon content. Biomet articulation seems to present the best factors selection. Passive corrosion of exposed metallic surfaces is represented by the elevated Ti levels found in all tested systems (Ti was not part of the bearing surfaces). The plasma sprayed acetabular component surface of the Zimmer’s component seems to be responsible for the significant difference in Ti versus the other implants


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 133 - 133
1 Mar 2008
Vendittoli P Roy A Mottard S Lavigne M
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Purpose: Tribological studies suggest that larger metal-on-metal articulations would produce less wear than smaller diameter components. The aim of the present study is to describe whole blood Chrome and Cobalt ions concentration after metal-metal total hip arthroplasty (THA) and surface replacement arthroplasty (SRA). Methods: 180 patients eligible for the study were randomized to receive uncemented 28 mm metal-metal THA or a hybrid metal-metal SRA. Whole blood samples were collected pre-operatively, at three, six months and one year post operatively. Chrome and Cobalt concentration were measured by mass spectrophotometry. Results: At one year post op, whole blood levels of the were Cr 1.8 umol/L and Co 0.6 umol/L for the SRA and Cr 1.7 umol/L and Co 0.8 umol/L for the THA group (Cr, p=0.676 and Co, p=0.08). In comparison to pre-operative levels, the post operative levels significantly incresed for all elements Cr 1.9x and Co 3.8x for the SRA; Cr 1.3x and Co 3.4x. for the SRA group, Anova regression tests showed a significant relation between component size and Cr and Co metal ions levels; the larger the component, the lower the ions levels (Cr p=0.0285 and Co p=0.0442). Conclusions: Using these specific implants, the increases whole blood metal ions were similar to the best results found in the literature for 28 mm metal-metal THA. Results of this study confirm the good tribologic performances of the Metasul large diameter metal-metal articulations. Funding: Commerical funding Funding Parties: Zimmer


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 74 - 74
1 Mar 2006
Motard S Vendittoli P Lavigne M Roy A Motard S
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Purpose: In 1988, metal-on-metal bearing surfaces were reintroduced in hip replacement surgery with a 28 mm diameter femoral head. These bearings have potential advantages such as improved durability, absence of polyethylene particles and no secondary periprosthetic osteolysis. Tribological studies suggest that larger metal-on-metal articulations would produce less wear than smaller diameter components. But recent clinical studies revealed increased release of circulating ions in metal-metal hip resurfacing compared to 28 mm metal-metal articulation. The aim of the present study is to describe whole blood Chrome and Cobalt ions concentration after non-cemented metal-metal total hip arthroplasty (THA) and hybrid metal-metal surface replacement arthroplasty (SRA). Method: All patients eligible for the study were randomised to receive uncemented THA or a hybrid SRA. Whole blood samples were collected pre-operatively, at three, six months and one year post operatively. Chrome and Cobalt concentration were measured using a spectrophotometer. Summary of Results: Blood samples have been taken from 78 patients and are pending analysis. Discussion: Considering the influence of activity level, weight, time after surgery, the renal function, etc. on the wear behaviour of bearing surfaces, a prospective randomised study is important to obtain a valid comparison. To our knowledge, this is the only randomised study comparing whole blood ions concentration in metal-metal THA and SRA. Significance: We strongly believe that this subject warrants special attention considering the possible toxicity associated with high levels of circulating metal ions


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XL | Pages 189 - 189
1 Sep 2012
Harding D Loesener G Ngyuen B Blackburn D Dixon R Taylor J
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Purpose. Total disc replacement (TDR) devices have been restricted to designs with large, congruent articulations due to the limited wear properties of available materials. TDRs with more natural motion could be designed if materials were available which could resist the higher wear conditions. A novel TriLobe TDR design is self-centering and energetically stable, emulating the natural motion of the intact motion segment, but is not feasible using traditional materials due to small incongruent articulating surfaces. The objective of this study was to compare the wear properties of a medical grade polycrystalline diamond with wear properties of cobalt chrome (CoCr) and ultrahigh molecular weight polyethylene (UHMWPE) in aggressive high wear conditions. Methods. A modified pin-on-disc, crossing-path wear test was used to measure the wear rates of PCD-on-PCD, CoCr-on-CoCr, and CoCr-on-UHMWPE. The discs were placed in the inferior position on an oscillating plate, moving in a 10mm by 5mm figure-eight pattern. Pins had an initial 11.5mm radius and were loaded at 133N normal to the disc. In a typical pin-on-disc test, a wear flat develops on the pin and the wear rate is reduced as the contact area increases. The TriLobe design uses three lobes sliding in three non-conforming lenses which prevents wear flats from developing. To approximate this condition, the fixture holding the disc was placed on an air bearing and was allowed to rock in concert with movement of the load. The test was conducted in 25% bovine serum at a speed of less than two Hertz. Two sets of each material were tested, one set to 2.0 million cycles and the other set to 14.0 million cycles. Wear rates on the rocking-discs were measured using a high resolution coordinate measuring machine because the wear in the PCD specimens was not detectable gravimetrically. Results. The diamond specimen averaged 0.0036mm. 3. /MC of wear over the first 2 million cycles. The CoCr-on-CoCr specimens averaged 1.4mm. 3. /MC and the CoCr-on-UHMWPE averaged 4.7mm. 3. /MC over 2 million cycles. The PCD specimen taken to 14 million cycles had and average wear of 0.0022mm. 3. /MC compared to 2.4mm. 3. /MC and 9.5mm. 3. /MC for CoCr-on-CoCr and CoCr-on-UHMWPE respectively. Conclusions. Using the pin-on-rocking-disc test to approximate small, non-congruent articulating surface wear, both CoCr-on-CoCr and CoCr-on-UHMWPE wore at rates that were orders of magnitude greater than medical grade PCD. At two million cycles, CoCr-on-CoCr had worn nearly 400 times more than PCD and CoCr-on-UHMWPE wore more than 1300 times greater. During the last 12 million cycles the wear in non-diamond specimen accelerated, while the diamond wear rate decreased. At the end of 14 million cycles CoCr on itself and on UHMWPE specimens had worn at more than 1100 times and nearly 4300 times greater than PCD, respectively. Coupled with the inherent biocompatibility, high strength and toughness, and ultra low friction of diamond, the performance of PCD makes it an attractive material for TDR applications. PCD could be used in current designs to alleviate concern over wear debris and ion release and to increase the space for the next generation of TDR devices


The Bone & Joint Journal
Vol. 101-B, Issue 1_Supple_A | Pages 41 - 45
1 Jan 2019
Jones CW De Martino I D’Apolito R Nocon AA Sculco PK Sculco TP

Aims

Instability continues to be a troublesome complication after total hip arthroplasty (THA). Patient-related risk factors associated with a higher dislocation risk include the preoperative diagnosis, an age of 75 years or older, high body mass index (BMI), a history of alcohol abuse, and neurodegenerative diseases. The goal of this study was to assess the dislocation rate, radiographic outcomes, and complications of patients stratified as high-risk for dislocation who received a dual mobility (DM) bearing in a primary THA at a minimum follow-up of two years.

Materials and Methods

We performed a retrospective review of a consecutive series of DM THA performed between 2010 and 2014 at our institution (Hospital for Special Surgery, New York, New York) by a single, high-volume orthopaedic surgeon employing a single prosthesis design (Anatomic Dual Mobility (ADM) Stryker, Mahwah, New Jersey). Patient medical records and radiographs were reviewed to confirm the type of implant used, to identify any preoperative risk factors for dislocation, and any complications. Radiographic analysis was performed to assess for signs of osteolysis or remodelling of the acetabulum.


The Bone & Joint Journal
Vol. 100-B, Issue 8 | Pages 1018 - 1024
1 Aug 2018
Ando W Yasui H Yamamoto K Oinuma K Tokunaga H Inaba Y Kobayashi N Aihara M Nakanishi R Ohzono K

Aims

The purpose of this study was to compare two different types of metal-on-metal (MoM) bearing for total hip arthroplasty (THA): one with a large femoral head (38 mm to 52 mm) and the other with a conventional femoral head (28 mm or 32 mm). We compared clinical outcome, blood metal ion levels, and the incidence of pseudotumour in the two groups.

Patients and Methods

Between December 2009 and December 2011, 62 patients underwent MoM THA with a large femoral head (Magnum group) and 57 patients an MoM THA with a conventional femoral head (conventional group). Clinical outcome was assessed using the Harris Hip score, University of California, Los Angeles (UCLA) activity score and EuroQol-5D (EQ-5D). Blood metal ion levels were measured and MRI scans were analyzed at a minimum of five years postoperatively.


The Bone & Joint Journal
Vol. 98-B, Issue 7 | Pages 910 - 916
1 Jul 2016
Pierrepont JW Feyen H Miles BP Young DA Baré JV Shimmin AJ

Aims

Long-term clinical outcomes for ceramic-on-ceramic (CoC) bearings are encouraging. However, there is a risk of squeaking. Guidelines for the orientation of the acetabular component are defined from static imaging, but the position of the pelvis and thus the acetabular component during activities associated with edge-loading are likely to be very different from those measured when the patient is supine. We assessed the functional orientation of the acetabular component.

Patients and Methods

A total of 18 patients with reproducible squeaking in their CoC hips during deep flexion were investigated with a control group of 36 non-squeaking CoC hips. The two groups were matched for the type of implant, the orientation of the acetabular component when supine, the size of the femoral head, ligament laxity, maximum hip flexion and body mass index.