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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_I | Pages 2 - 2
1 Jan 2012
Petersen T Larsen K Nordsteen J Olsen S Fournier G Jacobsen S
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Purpose. To compare the effectiveness of the McKenzie method and spinal manipulation when used adjunctive to information and advice for patients with clinical signs suggestive of disc-related symptoms for duration of more than 6 Weeks. Background. The conclusions drawn from previous randomised studies have been contradictory. The need for studies testing treatment strategies to specific diagnostic subgroups has been emphasised. Methods. After clinical screening, 350 patients who presented with centralisation/peripheralisation of symptoms with or without signs of disc herniation were randomised. The main outcomes were number of patients with treatment success and mean reduction on Roland Morris. Results. There was a significant difference in favour of the McKenzie group regarding treatment success at two months follow-up only (a between-group difference of 12%, p=0.02). The McKenzie group showed a better reduction in level of disability compared to the manipulation group that reached a statistical significance at two (mean difference 1.5 points, 95% CI 0.2-2.8, p= 0.02) and 12 months (mean difference 1.5 points, 95% CI 0.2-2.9, p= 0.03) follow-up. Conclusions. In patients with clinical signs of disc-related low back pain, the McKenzie method was slightly more effective than manipulation when used adjunctive to information and advice. The difference was of questionable clinical importance


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_I | Pages 34 - 34
1 Jan 2012
Bronfort G Maiers M Schulz C Evans R Bracha Y Svendsen K Grimm R Owens E Garvey T Transfeldt E
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Purpose

The importance of interpreting clinical trial results in terms of the benefits a treatment may offer to individuals with chronic pain is becoming more widely recognized. The clinical meaningfulness of group differences can better be described by looking at the percentages of responders in each treatment group, rather than between group mean differences. We have reassessed the outcomes of a clinical trial for chronic low back pain (LBP) from this new perspective.

Methods

The randomized clinical trial examined short- (12 weeks) and long-term (52 weeks) efficacy of high-dose, supervised trunk exercise (SET), spinal manipulative therapy (SMT), and a course of home exercise and self-care advice (HEA) for the treatment of LBP ≥ 6 weeks duration. We calculated response to care at 2 levels for 2 variables: numeric back pain scores (NRS) and Roland-Morris Disability (RMD), and at 3 timepoints (Weeks 12, 26 and 52). The 2 levels were calculated as percent improvement from baseline ≥ 30% and ≥75%. Finally, we calculated the relative proportion (± 95% confidence intervals) of the sample (∼100 per treatment group) that achieved each level of improvement.


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_9 | Pages 23 - 23
1 Oct 2022
Bhide J Hemming R Davies J
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Purpose of study and background. Psychological factors are considered to play a role in development and maintenance of chronic low back pain (CLBP). Stress or anxiety can change pain sensitivity; however, this has predominantly been studied in healthy individuals with limited work in individuals with musculoskeletal pain. The objective of this study was to quantify the effect of acute exposure to a psychosocial stressor on mechanical pain sensitivity in individuals with and without CLBP. Summary of methods and results. Six individuals with CLBP and 10 individuals without CLBP performed a 10-minute computer task under conditions of low and high psychosocial stress. Psychosocial stress was manipulated using mental maths and memory tasks combined with social evaluative threat. The effect of the stressor was evaluated using blood pressure, heart rate and the state anxiety component of the Spielberger State-Trait Anxiety Index. Mechanical pressure pain threshold (PPT) was recorded on the tibialis anterior muscle using a handheld digital pressure algometer. The stress manipulation increased self-reported anxiety (p<0.001), but not blood pressure or heart rate (p>0.06). Change in PPT from low to high stress was greater in the CLBP group (median ΔPPT = −0.5 kg/cm. 2. ) than in the control group (−0.15 kg/cm. 2. ; p=0.005). Conclusion. Individuals experienced an increase in pain sensitivity after acute exposure to a stressor designed to mimic low-level workplace stressors, and this increase was greater in individuals with CLBP than asymptomatic individuals. These results indicate that this experimental model can be used to study links between pain sensitivity and psychosocial stressors and increase our understanding of their potential role in CLBP. Conflicts of Interest: No conflicts of interest. Sources of funding: No funding obtained


Aims

The optimal procedure for the treatment of ossification of the posterior longitudinal ligament (OPLL) remains controversial. The aim of this study was to compare the outcome of anterior cervical ossified posterior longitudinal ligament en bloc resection (ACOE) with posterior laminectomy and fusion with bone graft and internal fixation (PTLF) for the surgical management of patients with this condition.

Methods

Between July 2017 and July 2019, 40 patients with cervical OPLL were equally randomized to undergo surgery with an ACOE or a PTLF. The clinical and radiological results were compared between the two groups.


The Bone & Joint Journal
Vol. 106-B, Issue 1 | Pages 53 - 61
1 Jan 2024
Buckland AJ Huynh NV Menezes CM Cheng I Kwon B Protopsaltis T Braly BA Thomas JA

Aims

The aim of this study was to reassess the rate of neurological, psoas-related, and abdominal complications associated with L4-L5 lateral lumbar interbody fusion (LLIF) undertaken using a standardized preoperative assessment and surgical technique.

Methods

This was a multicentre retrospective study involving consecutively enrolled patients who underwent L4-L5 LLIF by seven surgeons at seven institutions in three countries over a five-year period. The demographic details of the patients and the details of the surgery, reoperations and complications, including femoral and non-femoral neuropraxia, thigh pain, weakness of hip flexion, and abdominal complications, were analyzed. Neurological and psoas-related complications attributed to LLIF or posterior instrumentation and persistent symptoms were recorded at one year postoperatively.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXVII | Pages 35 - 35
1 Jun 2012
Noordeen H Elsebaie H Akbarnia B
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Introduction. Surgical correction of spinal deformities is a challenge; segmental instrumentation controlling almost every level is the most recent approach. Correction of the deformity only through apical manipulation has many potential advantages, including little tissue disruption, less invasive intervention, preservation of spinal mobility, and vertebral growth. However, quantification of the amount of force needed to pull on the apex and its effect on translation, de-rotation, and overall correction of the curve needs to be studied. The purpose of this study is to determine the effect and amount of force needed to pull on the apex of a scoliotic deformity towards the midline, and the feasibility of use of this novel potential method of correction in the treatment of patients with adolescent idiopathic scoliosis (AIS). Methods. Measurements were taken from 20 patients with AIS treated between June, 2009, and January, 2010. There were 16 female and 4 male patients with an average age of 14.2 years (range 11–20); the coronal preoperative Cobb angle was 67° (42–108°), decreasing on bending to 39° (8–83°), and the apex of the deformity was between T6 and L2. All patients had proximal and distal anchors spanning two levels on each end; the anchors were connected by a concave rod to which the apical vertebra was pulled. We measured the distance between the rod and the apical vertebra and the rotation of the apical vertebrae. Results. In 17 patients a force of 30 lb was applied and in 14 patients the force reached 40 lb. The apical baseline distance was 20.9 mm (10–40); at 30 lb of pull it decreased to 11.9 mm (0–27) and at 40 lb it was 9.4 mm (0–23) or 55% translation. The change in apical rotation was measured in 12 patients. The apex de-rotated in 10 of 12 patients, with a mean rotation of 5.2° (2–10°). Conclusions. Apical translation, vertebral de-rotation, and scoliosis correction can be done by application of a force pulling on a convex anchor at the apex of the curve towards a concave rod. With suitable instrumentation, deformity correction via manipulation of the apical vertebral body can be a valid treatment alternative through a less invasive approach, with little anatomical, biomechanical, and growth potential disruption


Bone & Joint Open
Vol. 3, Issue 5 | Pages 348 - 358
1 May 2022
Stokes S Drozda M Lee C

This review provides a concise outline of the advances made in the care of patients and to the quality of life after a traumatic spinal cord injury (SCI) over the last century. Despite these improvements reversal of the neurological injury is not yet possible. Instead, current treatment is limited to providing symptomatic relief, avoiding secondary insults and preventing additional sequelae. However, with an ever-advancing technology and deeper understanding of the damaged spinal cord, this appears increasingly conceivable. A brief synopsis of the most prominent challenges facing both clinicians and research scientists in developing functional treatments for a progressively complex injury are presented. Moreover, the multiple mechanisms by which damage propagates many months after the original injury requires a multifaceted approach to ameliorate the human spinal cord. We discuss potential methods to protect the spinal cord from damage, and to manipulate the inherent inhibition of the spinal cord to regeneration and repair. Although acute and chronic SCI share common final pathways resulting in cell death and neurological deficits, the underlying putative mechanisms of chronic SCI and the treatments are not covered in this review.


Bone & Joint Open
Vol. 2, Issue 7 | Pages 540 - 544
19 Jul 2021
Jensen MM Milosevic S Andersen GØ Carreon L Simony A Rasmussen MM Andersen MØ

Aims

The aim of this study was to identify factors associated with poor outcome following coccygectomy on patients with chronic coccydynia and instability of the coccyx.

Methods

From the Danish National Spine Registry, DaneSpine, 134 consecutive patients were identified from a single centre who had coccygectomy from 2011 to 2019. Patient demographic data and patient-reported outcomes, including pain measured on a visual analogue scale (VAS), Oswestry Disability Index (ODI), EuroQol five-dimension five-level questionnaire, and 36-Item Short-Form Health Survey questionnaire (SF-36) were obtained at baseline and at one-year follow-up. Patient satisfaction was obtained at follow-up. Regression analysis, including age, sex, smoking status, BMI, duration of symptoms, work status, welfare payment, preoperative VAS, ODI, and SF-36 was performed to identify factors associated with dissatisfaction with results at one-year follow-up.


The Bone & Joint Journal
Vol. 103-B, Issue 3 | Pages 542 - 546
1 Mar 2021
Milosevic S Andersen GØ Jensen MM Rasmussen MM Carreon L Andersen MØ Simony A

Aims

The aim of this study was to investigate the efficacy of coccygectomy in patients with persistent coccydynia and coccygeal instability.

Methods

The Danish National Spine Registry, DaneSpine, was used to identify 134 consecutive patients who underwent surgery, performed by a single surgeon between 2011 and 2019. Routine demographic data, surgical variables, and patient-reported outcomes, including a visual analogue scale (VAS) (0 to 100) for pain, Oswestry Disability Index (ODI), EuroQol five-dimension questionnaire (EQ-5D), and the Physical Component Score (PCS) and Mental Component Score (MCS) of the 36-Item Short-Form Health Survey questionnaire (SF-36) were collected at baseline and one-year postoperatively.


The Bone & Joint Journal
Vol. 103-B, Issue 3 | Pages 547 - 552
1 Mar 2021
Magampa RS Dunn R

Aims

Spinal deformity surgery carries the risk of neurological injury. Neurophysiological monitoring allows early identification of intraoperative cord injury which enables early intervention resulting in a better prognosis. Although multimodal monitoring is the ideal, resource constraints make surgeon-directed intraoperative transcranial motor evoked potential (TcMEP) monitoring a useful compromise. Our experience using surgeon-directed TcMEP is presented in terms of viability, safety, and efficacy.

Methods

We carried out a retrospective review of a single surgeon’s prospectively maintained database of cases in which TcMEP monitoring had been used between 2010 and 2017. The upper limbs were used as the control. A true alert was recorded when there was a 50% or more loss of amplitude from the lower limbs with maintained upper limb signals. Patients with true alerts were identified and their case history analyzed.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_I | Pages 48 - 48
1 Jan 2012
Stochkendahl MJ Christensen HW Vach W H⊘ilund-Carlsen PF Haghfelt T Hartvigsen J
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Background and purpose. The musculoskeletal system is a common, but often overlooked, cause of chest pain. Little is known about the efficacy of spinal manipulation for this condition. The purpose of the present study is to evaluate the relative effectiveness of two conservative treatment approaches for acute musculoskeletal chest pain, 1) a spinal manipulation-based therapy as a typical example of chiropractic treatment and 2) self-management as an example of minimal intervention. Methods and results. In a non-blinded, randomised controlled trial set at an emergency cardiology department and four outpatient chiropractic clinics, 115 consecutive patients with acute chest pain and no clear medical diagnosis at initial presentation were included. After a baseline evaluation, patients with musculoskeletal chest pain were randomized to four weeks of chiropractic treatment or self-management, with post-treatment questionnaire follow-up four and 12 weeks later. Primary outcome measures were numeric change in pain intensity (11-point box numerical rating scale) and self-perceived change in pain (7-point ordinal scale). Secondary measures included Medical Outcomes Study Short Form 36 (SF-36) scores, change in pain intensity (chest, thoracic spine, neck and shoulder/arm), and self-perceived change in general health. Preliminary results will be available at the time of presentation. Conclusions. This is the first randomised controlled trial assessing chiropractic treatment versus a minimal intervention in patients with musculoskeletal chest pain. Results will indicate whether chiropractic treatment is a useful option for patients with musculoskeletal chest pain, but the design does not allow for standardisation of treatment or identification of potentially active ingredients of care


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXVI | Pages 34 - 34
1 Jun 2012
Rao P Pugh S Ahuja S
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Introduction. Reported incidence of DVT after spinal surgery ranges from 0-15% and PE 0.5-2.7%. Theoretically, manipulation of the vessels and venous stasis caused by retraction during anterior lumbar inter-body fusion may increase the propensity for thrombosis. The reported incidence of DVT and PE following major abdominal and pelvic surgery are high (up to 23%) and all these patients routinely receive chemical prophylaxis. Aim. Should patients undergoing ALIF surgery receive chemical prophylaxis routinely?. Materials and Methods. Retrospective review of ALIF procedures done between Jan 2007- Jan 2010. Review of case notes, radiology reports and telephone call to the patients to exclude DVT. Total of 76 patients underwent ALIF during this period. Forty six were female(60.5%) and 36 were 2 level fusions(47%). L5-S1 being commonly fused (76%) followed by L4-L5 (23%). Average surgical time from theatre records is 115 minutes(31-369 minutes). All patients received mechanical prophylaxis in the form of thigh length TED stockings. None of the patients were on treatment for DVT prior to surgery. Results. Three patients (3.9%) had Doppler proved DVT which required anticoagulation treatment. There was no reported incidence of PE. Discussion. There is no definite evidence in the literature to suggest ALIF surgery has higher incidence of thromboembolic complications, though theoretical possibility of increased risk. Current study suggests that incidence is 3.9% with mechanical prophylaxis alone which is very small when compared to incidence after major abdominal, pelvic or gynaecological procedures. Our small study sample suggests routine use of chemical prophylaxis to reduce the risk of DVT for anterior lumbar inter-body fusion is not justified


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_I | Pages 54 - 54
1 Jan 2012
Mieritz RM
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Advisors. PhD J Hartvigsen, PhD P Aagaard, University of Southern Denmark. PhD G Br⊘nfort, Northwestern Health Sciences University, Minneapolis, MN, USA and NIKKB. PhD G Kawchuk, Canada Research Chair in Spinal Function, University of Edmonton, Alberta, Canada. PhD A Breen, Institute for muscoloskeletal research & clinical implementation, Bournemouth, England. PhD J Rasmussen, Institut for Maskinteknik og Anybody Group, Aalborg Universitet. Introduction. The overall issue of this project is to investigate the relationship between the lumbar spinal biomechanics, patient's pain and physiological effects of traditional conservative treatments. Background. Biomechanical factors such as ranges, patterns and quality of motion in the lumbar spine are thought to be important contributors to many varieties of LBP. Furthermore, commonly used treatments for spine pain such as exercises, training, and various manual treatments such as manipulation are thought to alter biomechanical factors and thereby facilitating return to “normal” function and thus a pain free state. Method. A systematic critical literature review in order to determine the current reproducibility level for measuring 3D regional lumbar spinal motion with various methods and based on the review propose an agenda for future research. Develop of a model to analyze the dynamic non-invasive computerized regional motion data. In this model the complex motion data will be reduced to a manageable size with each movement parameter consisting of individual figures. The data reduction will be done in a developed MATLAB program and the analysis of the reduced data will be handled in STATA. Use collected data from randomized clinical trials (research center at Northwestern Health Sciences University in Minnesota, USA) on the developed model in a reproducibility study and an intervention study


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_I | Pages 4 - 4
1 Jan 2012
Hider S Foster N
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Background. Patient preferences have been shown to be associated with treatment effects (. 1. ) and recent national guidelines suggest using patient preferences to help inform clinical interventions (. 2. ). Aim. To determine the treatment preferences of LBP patients and whether these affect clinical outcome. Methods. Prospective cohort study of UK primary care LBP consulters (n=1591). Questionnaires were completed at baseline and 6 months including data on back pain and disability (Roland Morris Disability Questionnaire; RMDQ). Patients were asked “What treatment would you prefer to have for your back problem?” (response in free text, asked to indicate “none” if no preference). Results. One third of patients (612/1591, 38%) expressed no treatment preference. Those who expressed preferences (696/1591, 44%) did so most often for physiotherapy or exercise (192/1591 12%), chiropractic (91/1591, 6%) or osteopathy (85/1591, 5%). Patients expressing treatment preferences were likely to be younger (median age 44 years vs. 46 years, p=0.0008) and employed (55% vs. 44%, p=0.036) than those with no preferences. No gender differences were observed. Expressing treatment preferences did not appear to affect the treatment that patients received, 58% received GP advice or medication, 18% physiotherapy, 5% chiropractic and 4% osteopathy. Treatment preferences were not associated with clinical outcome (RMDQ) at any follow-up. Conclusions. A significant proportion of LBP patients do not express treatment preferences. Even those expressing preferences for exercise or manipulation were more likely to receive GP advice or medication. Therefore, using patient preferences to inform treatment may be difficult to implement in practice


The Bone & Joint Journal
Vol. 102-B, Issue 1 | Pages 5 - 10
1 Jan 2020
Cawley DT Rajamani V Cawley M Selvadurai S Gibson A Molloy S

Aims

Intraoperative 3D navigation (ION) allows high accuracy to be achieved in spinal surgery, but poor workflow has prevented its widespread uptake. The technical demands on ION when used in patients with adolescent idiopathic scoliosis (AIS) are higher than for other more established indications. Lean principles have been applied to industry and to health care with good effects. While ensuring optimal accuracy of instrumentation and safety, the implementation of ION and its associated productivity was evaluated in this study for AIS surgery in order to enhance the workflow of this technique. The aim was to optimize the use of ION by the application of lean principles in AIS surgery.

Methods

A total of 20 consecutive patients with AIS were treated with ION corrective spinal surgery. Both qualitative and quantitative analysis was performed with real-time modifications. Operating time, scan time, dose length product (measure of CT radiation exposure), use of fluoroscopy, the influence of the reference frame, blood loss, and neuromonitoring were assessed.


The Bone & Joint Journal
Vol. 102-B, Issue 3 | Pages 371 - 375
1 Mar 2020
Cawley D Dhokia R Sales J Darwish N Molloy S

With the identification of literature shortfalls on the techniques employed in intraoperative navigated (ION) spinal surgery, we outline a number of measures which have been synthesised into a coherent operative technique. These include positioning, dissection, management of the reference frame, the grip, the angle of attack, the drill, the template, the pedicle screw, the wire, and navigated intrathecal analgesia. Optimizing techniques to improve accuracy allow an overall reduction of the repetition of the surgical steps with its associated productivity benefits including time, cost, radiation, and safety.

Cite this article: Bone Joint J 2020;102-B(3):371–375.


The Bone & Joint Journal
Vol. 99-B, Issue 12 | Pages 1658 - 1664
1 Dec 2017
Ahmad A Subramanian T Panteliadis P Wilson-Macdonald J Rothenfluh DA Nnadi C

Aims

Magnetically controlled growing rods (MCGRs) allow non-invasive correction of the spinal deformity in the treatment of early-onset scoliosis. Conventional growing rod systems (CGRS) need repeated surgical distractions: these are associated with the effect of the ‘law of diminishing returns’.

The primary aim of this study was to quantify this effect in MCGRs over sequential distractions.

Patients and Methods

A total of 35 patients with a maximum follow-up of 57 months were included in the study. There were 17 boys and 18 girls with a mean age of 7.4 years (2 to 14). True Distraction (TD) was determined by measuring the expansion gap on fluoroscopy. This was compared with Intended Distraction (ID) and expressed as the ‘T/I’ ratio. The T/I ratio and the Cobb angle were calculated at several time points during follow-up.


The Bone & Joint Journal
Vol. 100-B, Issue 1 | Pages 81 - 87
1 Jan 2018
Peng B Yang L Yang C Pang X Chen X Wu Y

Aims

Cervical spondylosis is often accompanied by dizziness. It has recently been shown that the ingrowth of Ruffini corpuscles into diseased cervical discs may be related to cervicogenic dizziness. In order to evaluate whether cervicogenic dizziness stems from the diseased cervical disc, we performed a prospective cohort study to assess the effectiveness of anterior cervical discectomy and fusion on the relief of dizziness.

Patients and Methods

Of 145 patients with cervical spondylosis and dizziness, 116 underwent anterior cervical decompression and fusion and 29 underwent conservative treatment. All were followed up for one year. The primary outcomes were measures of the intensity and frequency of dizziness. Secondary outcomes were changes in the modified Japanese Orthopaedic Association (mJOA) score and a visual analogue scale score for neck pain.


The Journal of Bone & Joint Surgery British Volume
Vol. 94-B, Issue 11 | Pages 1442 - 1447
1 Nov 2012
Sharma H Lee SWJ Cole AA

Spinal stenosis and disc herniation are the two most frequent causes of lumbosacral nerve root compression. This can result in muscle weakness and present with or without pain. The difficulty when managing patients with these conditions is knowing when surgery is better than non-operative treatment: the evidence is controversial. Younger patients with a lesser degree of weakness for a shorter period of time have been shown to respond better to surgical treatment than older patients with greater weakness for longer. However, they also constitute a group that fares better without surgery. The main indication for surgical treatment in the management of patients with lumbosacral nerve root compression should be pain rather than weakness.


The Journal of Bone & Joint Surgery British Volume
Vol. 93-B, Issue 8 | Pages 1084 - 1087
1 Aug 2011
Tauchi R Imagama S Kanemura T Yoshihara H Sato K Deguchi M Kamiya M Ishiguro N

We reviewed seven children with torticollis due to refractory atlanto-axial rotatory fixation who were treated in a halo vest. Pre-operative three-dimensional CT and sagittal CT imaging showed deformity of the superior articular process of C2 in all patients. The mean duration of halo vest treatment was 67 days (46 to 91). The mean follow-up was 34 months (8 to 73); at the latest review six patients demonstrated remodelling of the deformed articular process. The other child, who had a more severe deformity, required C1-2 fusion.

We suggest that patients with atlanto-axial rotatory fixation who do not respond to conservative treatment and who have deformity of the superior articular process of C2 should undergo manipulative reduction and halo-vest fixation for two to three months to induce remodelling of the deformed superior articular process before C1-2 fusion is considered.