The Columbus is a relatively new implant with no published medium or long term follow-up. Its extensive use within our department led to this study to review the five-year clinical outcomesof patients who had a navigated Columbus primary total knee arthroplasty (TKA) implanted between March 2005 and December 2006. Case notes, departmental and hospital databases and PACS were used to identify patients and collect routine five-year review data. Information Services Division was approached for all cases of re-admission and associated complications anywhere in Scotland. 219 (90 male, 116 left) patients were identified. Mean age was 69 years (48–89) and mean BMI 32.2 (SD 5.8). Of the 219 patients operated on, twenty-one had a complication; ten still had intermittent mild to moderate pain, three had wound problems, one had a washout, one had DVT/PE within ninety days and one was diagnosed with patellar clunk syndrome. The remaining five patients had revision TKA (revision rate 2.3%), four for infection and only one due to aseptic loosening (revision rate excluding infection 0.5%). 115 patients returned to clinic at five years. Of these 96.4% were satisfied with their operation. The mean Oxford knee score had reduced from 42.5 (SD 8.2) pre-operatively to 23.6 (SD 9.2). Mean fixed flexion was 1° (SD 2.8°, range 0° to 15°) with four patients having a fixed flexion of 6° or more. Mean maximum flexion was 100° (SD 10.2°, range 60° to 120°) with two patients having flexion less than 80°. X-ray analysis showed that fourteen patients had a radiolucent line. Nine of these were not present at one year, six being at the tibial component. These results are satisfactory. The revision rate is similar to that cited by the National Joint Registry report 2011 (2.5%). Furthermore, the revision rate excluding infection is very low

We examined osteochondral autografts, obtained at a mean of 19.5 months (3 to 48) following extracorporeal irradiation and re-implantation to replace bone defects after removal of tumours. The specimens were obtained from six patients (mean age 13.3 years (10 to 18)) and consisted of articular cartilage (five), subchondral bone (five), external callus (one) and tendon (one). The tumour cells in the grafts were eradicated by a single radiation dose of 60 Gy. In three cartilage specimens, viable chondrocytes were detected. The survival of chondrocytes was confirmed with S-100 protein staining. Three specimens from the subchondral region and a tendon displayed features of regeneration. Callus was seen at the junction between host and irradiated bone.