Aim. A substantial portion of periprosthetic joint infections (PJI) literature is comprised of observational studies. The Strengthening the Reporting of Observational Studies in Epidemiology guidelines emphasize the importance of clearly defining variables and providing diagnostic criteria. Well-defined variables in these studies play a crucial role in ensuring data consistency, fostering comparability among studies, and laying a robust foundation for evidence-based decision-making. We aimed to determine the definition of these variables and determine the objectivity of the definitions. Method. We reviewed observational studies on hip or knee PJI that focused on variables and their association with treatment outcomes. The inclusion criteria comprised studies from Jan 2017 to Jan 2023. We focused on 13 variables that were possibly subjective. These were smoking, alcohol use, diabetes mellitus, hypertension, lung disease, rheumatoid arthritis, liver diseases, kidney diseases, cardiovascular diseases, malignancy, immunosuppression, use of antibiotics, and type of infection. The reviewers examined the text of the articles, along with any available online supplements or protocols, for definitions of the selected variables. We classified a definition as objective if there was the presence of time element, severity, staging, frequencies, laboratory cut-off, medication dependence, among others. Chart review was deemed subjective. Results. We included 75 studies in the analysis. The most common factors studied were diabetes mellitus (79%), cardiovascular disease, smoking history, and rheumatoid arthritis (47% each). The variables that were objectively defined most often were antibiotic use (100%) and type of infection (95%). Smoking history (16%) and alcohol use (20%) were the least frequently objectively defined variables. Further analysis revealed that a considerable number of studies incorporated variables into their primary analyses without clear definitions. For instance, out of the 59 studies where diabetes was considered a variable, 41 studies (70%) included diabetes in their main analyses as a factor for PJI treatment outcomes, despite only 34 studies having defined this variable. Moreover, of the 34 provided definitions of diabetes mellitus, only 12 provided objective criteria for diagnosis. The rest of the provided definitions relied on “chart review” without further specification. Table 1 outlines the proportion of studies with variables defined and included in their analysis. Conclusions. Study variables were not clearly defined in most of the observational studies raising concerns about the reproducibility and reliability of findings. Our study underscores the vital need for standardized variable definitions in PJI research. Professional societies may play a crucial role in setting standards for the definition of variables. For any tables or figures, please contact the authors directly

There is great debate around how to treat patients with periprosthetic joint infections and there are different techniques utilised throughout the world with large regional differences. In the situation where implants are well fixed there is a potential advantage to retain ingrown implants in which removal would result in severe bone damage. However, there are multiple variables on both the patient side and the surgeon side which can influence the likelihood of success with this approach. In some patients, staged revision of large and well-fixed components will result in bone damage and compromised function, but the two-stage techniques may have great success at long term infection free survivorship. The literature suggests that selective implant retention and joint débridement may be an alternative for those patients who have complex well-fixed components, are not immunocompromised, have not developed sinus formation, and who have less virulent organisms on aspiration. Implant retention techniques should be approached with caution when patients have chronic illness such as diabetes or rheumatoid disease, use immunosuppressive medications, have a negative aspirate for microorganisms, or show any signs of loosening on radiographs or during intra-operative assessment. Like many aspects of patient care, proper patient selection and meticulous surgical techniques are important components to increasing success in these difficult clinical scenarios. This talk will focus on the data currently available in the literature to help participants gain a better understanding of how to individualise treatments for patients with periprosthetic infections

Introduction. Limb length discrepancy (LLD) is one of the major reasons of dissatisfaction after total hip arthroplasty(THR) and limb equalization after THR in unilateral developmental dysplasia of the hip (DDH) is very important. study designed to measure the difference of adult femoral length between normal and dislocated hip in unilateral DDH. Method. Sixty patients with unilateral high riding DDH (crow type 3,4) who were underwent THR included. All the cases had digital lower limb scanograms. Exclusion criteria was any previous hip or femur surgery, any rheumatoid disease, history of any disease that affect the growth. All the scanograms measured by one fellowship of adult reconstruction and one radiologist specialized in musculoskeletal imaging. Each one repeated the measurements two months later blindly and inter observer and intra observer reliability checked. Each one measured femoral length in both sides from greater trochanter(GT), to the distal surface of the femoral condyles. Results. 59 female and one males included. Average age was 27.5 years (19–50 years). Inter observer reliability index were excellent (ICC 98%). Only 6 cases (10%) had exactly equal femoral length, 31(52%) cases were longer on the dislocated side and 23 (38%) cases were shorter. Average overgrowth was 6.1 mm (Range: 1–22) and average undergrowth was 10.7 (Range 1–21). 35 cases (58.3%) cases had 5 mm or more differences and 30% had 5–10 mm .17 cases (28.3%) had at least 10 mm difference that 8 cases (13%) had shorter and 9 cases (15%) had longer femur on dislocated side. Maximum difference was 22 mm over length on dislocated side. Conclusions. More than half of patients with unilateral high riding DDH have longer femur on the dislocated side and 15% of them are longer than 10 mm. we recommend to get the scanograms in all the unilateral DDH cases to avoid post-operative limb discrepancy and detecting the amount of shortening in cases that need femoral shortening

Hind and mid foot arthritis is often noted in patients who have previously had an ankle arthrodesis. It has been suggested that this arthritis may be precipitated or exacerbated as a direct result of the ankle fusion. The aim of this study was to investigate the degree and pattern of pre-existing ipsilateral foot arthritis in patients who have subsequently undergone ankle arthrodesis. A retrospective review of the most recent pre-operative radiographs of 70 patients who underwent 71 arthrodeses between 1993-2003 was performed. Patients with rheumatoid disease were excluded. The immediate pre-operative AP and lateral ankle radiographs were assessed and the presence and severity of osteoarthritis for the sub-talar, talo-navicular, naviculo-cuneiform and calcaneo-cuboid joints was recorded using the Kellgren and Lawrence grading score. This was performed simultaneously by two reviewers and a consensus obtained. A total score out of 16 was given for each radiograph. 68 (96%) of the radiographs reviewed showed evidence of pre-existing hind or mid foot arthritis prior to ankle fusion. The sub-talar joint was the most commonly and severely affected. The median total arthritis score for each radiograph was 5. There was no association between age or causative pathology and the degree of arthritis. This study has demonstrated that hind and mid foot arthritis is very common in patients with co-existent ankle arthritis prior to ankle fusion. This has previously been assumed to have developed as a result of the surgery but is, in fact, present at the time of the operation and this needs to be taken into consideration when evaluating the results of ankle arthrodesis

Twenty-four replacements were performed in 19 patients (13 female: 6 male), with average age of 33 years (18-40). All had severe polyarticular rheumatoid arthritis. Pre-operatively 12 ankles had no angular deformity, 9 were in valgus and 3 in varus. All had associated hindfoot disease. Some of these patients are part of two larger studies of the Scandinavian Total Ankle Replacement (STAR) and the Buechel-Pappas (BP) replacement. In this group there were 20 STAR and 4 BP replacements. Average follow-up was 62 months (36 to 120). Twenty-one replacements had good pain relief and function. The AOFAS hindfoot score for pain improved from 0 to 36 (max 40) and for function from 25 to 35 (max 60). Three have failed. One ankle had a 25-degree valgus deformity pre-operatively and this recurred and caused failure at 11 months. The second failed at 34 months due to aseptic loosening of the talar component. Both of these were converted to tibio-talo-calcaneal fusions with an intra-medullary nail. The third failure had never provided satisfactory pain relief in spite of appearing satisfactory on clinical and radiological examination. Exploratory surgery was carried out at 36 months but failed to produce an improvement and at 61 months the decision was made to revise the replacement to a fusion. However, due to concurrent health problems, this has not yet been done. We offer replacement to patients with severe polyarticular rheumatoid disease especially if there is a stiff but well aligned hindfoot. In the light of increased experience, we now consider valgus or varus deformity of greater than 20 degrees to be a contra-indication to replacement. This is because the deformity tends to recur leading to pain, loosening and failure

The Mathys. ¯. finger joint replacement system offers a novel fixation method into the proximal and distal medullary canals and a semi-constrained articulation. This comprises a separable, form-fit joint with a distal/proximal play of 0.7 mm, a lateral excursion of 10°, and rotation of up to 6°. This has theoretical advantages of increased radio-ulnar stability, preventing ulnar drift in patients with rheumatoid disease, and enhanced osseointegration offering implant longevity. In our unit, however, high failure rates were noted, prompting a review of cases to quantify our suspicions. Case notes of all patients who underwent finger joint replacement using the Mathys. ¯. implant between 1999 and 2005 were retrieved. Twenty-two devices were implanted by a single surgeon during this period. Four were in finger proximal interphalangeal joints, 17 in finger metacarpophalangeal joints and one in a thumb carpometacarpal joint (CMCJ). Indications for joint replacement included sixteen for rheumatoid arthritis (RA) and five for post-traumatic joint problems. The only thumb CMCJ was replaced for primary osteoarthritis. Patients were reviewed regularly and implant performance assessed critically along with survival of the implant to revision, infection or death of the patient. Mean follow up was 30 months. Sixteen implants failed including the only thumb CMCJ. Modes of failure were rotation (11), poor range of motion (two), infection (two) and dislocation (the CMCJ). Similar ball and socket designs for uncemented thumb CMCJ replacement, such as the Ledoux prosthesis, have previously shown poor survival and have been withdrawn from the market. Of the finger implants in RA patients (n=16), 12 implants failed of which ten were due to rotation. Time to failure ranged from two to 48 months (mean 15 months). The authors do not recommend the use of this implant, especially in cases of rheumatoid arthritis

Various surgical treatment were reported on rheumatoid shoulder. However, there were no recommended surgeries in the Japanese 2. nd. basic published text of rheumatoid disease. We had performed total shoulder arthroplasty(TSA) and humeral head replacement (HHR) in patient with Rheumatoid shoulder from 1992. The aim of this study was to compare the outcome of humeral head replacement, 2. nd. generation TSA and 3. rd. generation TSA in patients followed more than 5 years with rheumatoid shoulder. Material & Method. From 1992–2007, we performed shoulder arthroplasty in 42 shoulders in 40 patients. Six cases were not able to follow due to die and lost. All 36 shoulders in 34 patients could be followed with x-ray examinations more than 5 years. Averaged follow-up period was 8.6 years (range 5–14.5). HHR with intact cuff performed in 10 shoulders, 2. nd. generation TSA with intact cuff in 10, 3. rd. generation TSA in intact cuff in 10 and HHR with muscle tendon transfer in 6 shoulders. The shoulder score of Japanese Orthopaedic Association)JOA score. Modified Neer classification, ROM, lucent lines in X-ray and complications were investigated. Results. In JOA score, 3. rd. generation TSA revealed highest score (84 points). Also, in Modified Neer classification, excellent results were obtained 50% of cases in 3. rd. generation TSA. On the other hand, HHR with muscle tendon transfer group has no cases of excellent results. In flexion & external rotation, 3. rd. generation TSA had achieved satisfactory results. In X-ray, all glenoid component had a lucent line around the keel type glenoid in 2. nd. generation TSA. However, only 1.6 points in Lazarus claasification revealed in peg type component in 3. rd. generation TSA. No nerve injuries and instability were found after surgery. However, two infections and two glenoid resurfacing need after surgery. Discussion. In this mid-term results, 3. rd. generation type of TSA system could get favorable results in RA shoulders with intact cuff. However, the treatment for rheumatoid shoulder cases which has masssive rotator cuff defect is still remained as difficult problem

Introduction. The purpose of this study was to introduce our perioperative prophylaxis method for infection and clarify surgical site infection rate in our patients performed total hip arthroplasty (THA). Method. Two hundred and eighty four THA (including revision 18 cases) performed by single surgeon between Oct. 2007 and Jan. 2013 were evaluated. The mean age of patients was 65.7 years old. The male to female ratio was 46 to 238. BMI was 23.6. Ninety patients (32%) were compromised host suffering from diabetes mellitus, rheumatoid arthritis, autoimmune disease, history of malignant tumor, hemodialysis or skin disease at surgical site respectively. At preoperative period, we checked decayed tooth, alveolar pyorrhea, hemorrhoids, and leg skin condition. In addition, we examined culture of nasal cavity. At the day of surgery, patient took a shower just before entering surgical room. All of THA was performed in clean room NASA class 100. Surgeons and assistant nurse put on nonwoven fabric gown, space suit and double rubber gloves. We wiped surgical site leg by gauze impregnated by 0.5% chlorhexidine alchohol to eliminate skin bacteria twice just before surgeons scrubbing hands. Surgical site was covered by povidone iodine containing drape. Surgeons or nurse changed gloves when glove was broken at each time. We cleaned surgical field by pulse washer whenever necessary. We did not use drain except for 5 revision THAs. Regarding to prophylactic antibiotics usage, we administered cefcapene pivoxil orally the day before surgery. Drip infusion antibiotics (PIPC: until Oct. 2008, CEZ: after Oct. 2008) was administered at the period of 30 min. before surgery and 4 hours after surgery in case of prolonged surgical time (4 hours >). Skin closure was performed by staple and covered by gauze until May 2010. After that, we used surgical tape and transparent water proof sheet. After finishing surgery, antibiotic was administered 8 hours interval at surgery day and 12 hours interval for additional two days. In case multi-drug resistant bacteria (MRSA, MRSE) was positive in nasal culture, we applied mupirocin ointment to nasal cavity for 3 days before surgery and administered vancomycin (from Aug. 2011) or linezolid (from 2012) for prophylactic antibiotics in perioperative period. Results. Multi-drug resistant bacteria was detected from nasal cavity in 23 patients (8%). The mean operation time was 194 min (due to education for young surgeon). Intraoperative bleeding was 598g. Length of skin incision was 13.6 cm. Intraoperative wash volume was 4500 ml. The infection rate were 0 % in early period and 0.7 % (two case) in late period respectively. One infected case was 75 years old female. Deep infection was occurred 3 years after surgery. She was administered steroid and immunosuppressive drug due to metal allergy after total knee arthroplasty. The other case was 64 years old female. Superficial infection happened 3 months after THA. The patient was suffered from collagen disease and diabetes. Conclusion. Our prophylaxis method for surgical site infection of THA achieved 0 % in early infection and 0.7% late chronic infection respectively

For any image guided surgery, independently of the technique which is used (navigation, templates, robotics), it is necessary to get a 3D bone surface model from CT or MR images. Such model is used for planning, registration and visualization. We report that graphical representation of patient bony structure and the surgical tools, inter-connectively with the tracking device and patient-to-image registration, are crucial components in such system. For Total Shoulder Arthroplasty (TSA), there are many challenges. The most of cases that we are working with are pathological cases such as rheumatoid arthritis, osteoarthritis disease. The CT images of these cases often show a fusion area between the glenoid cavity and the humeral head. They also show severe deformations of the humeral head surface that result in a loss of contours. These fusion area and image quality problems are also amplified by well-known CT-scan artefacts like beam-hardening or partial volume effects. The state of the art shows that several segmentation techniques, applied to CT-Scans of the shoulder, have already been disclosed. Unfortunately, their performances, when used on pathological data, are quite poor. In severe cases, bone-on-bone arthritis may lead to erosion-wearing away of the bone. Shoulder replacement surgery, also called shoulder arthroplasty, is a successful, pain-relieving option for many people. During the procedure, the humeral head and the glenoid bone are replaced with metal and plastic components to alleviate pain and improve function. This surgical procedure is very difficult and limited to expert centres. The two main problems are the minimal surgical incision and limited access to the operated structures. The success of such procedure is related to optimal prosthesis positioning. For TSA, separating the humeral head in the 3D scanner images would allow enhancing the vision field for the surgeon on the glenoid surface. So far, none of the existing systems or software packages makes it possible to obtain such 3D surface model automatically from CT images and this is probably one of the reasons for very limited success of Computer Assisted Orthopaedic Surgery (CAOS) applications for shoulder surgery. This kind of application often has been limited due to CT-image segmentation for severe pathologic cases and patient to image registration. The aim of this paper is to present a new image guided planning software based on CT scan of the patient and using bony structure recognition, morphological and anatomical analysis for the operated region. Volumetric preoperative CT datasets have been used to derive a surface model shape of the shoulder. The proposed planning software could be used with a conventional localisation system, which locates in 3D and in real time position and orientation for surgical tools using passive markers associated to rigid bodies that will be fixed on the patient bone and on the surgical instruments. 20 series of patients aged from 42 years to 91 years (mean age of 71 years) were analysed. The first step of this planning software is fully automatic segmentation method based on 3D shape recognition algorithms applied to each object detected in the volume. The second step is a specific processing that only treats the region between the humerus and the glenoid surface in order to separate possible contact areas. The third step is a full morphological analysis of anatomical structure of the bone. The glenoid surface and the glenoid vault are detected and a 3D version and inclination angle of the glenoid surface are computed. These parameters are very important to define an optimal path for drilling and reaming glenoid surface. The surgeon can easily modify the position of the implant in 3D aided by 3D and 2D view of the patient anatomy. The glenoid version/inclination angle and the glenoid vault are computed for each postion in real time to help the surgeon to evaluate the implant position and orientation. In summary, preoperative planning, 3D CT modelling and intraoperative tracking produced improved accuracy of glenoid implantation. The current paper has presented new planning software in the world of image guided surgery focused on shoulder arthroplasty. Within our approach, we propose, to use pattern recognition instead of manual picking of landmarks to avoid user intervention, in addition to potentially reducing the procedure time. A very important role is played by 3D data sets to visualise specific anatomical structures of the patient. The automatic segmentation of arthritic joints with bone recognition is intended to form a solid basis for the registration. The results of this methodology were tested on arthritic patients to prove that it is not just easy and fast to perform but also very accurate so it realises all conditions for the clinical use in OR