Background and aim. Total hip replacement (THR) in young patients has been associated to higher revision rates than in older population. Different conditions may lead to end-stage arthritis of the hip in these patients. We compared the clinical and radiological outcome of two different groups of young and very young patients who underwent a ceramic-on-ceramic THR. Patients and Methods. 120 hips were prospectively followed for a mean of 10.4 years (range, 5 to 17). 38 patients (46 hips) were less than 30 years old (group 1), and, 68 (74 hips) were between 31 and 40 years old (group 2). Weight (p<0.001) and physical activity level were greater in group 2 (p<0.001). Preoperative function (p=0.03) and range of mobility (p=0.03) were worse in group 1. Primary osteoarthritis was not found in any case. Rheumatoid juvenile arthritis was the most frequent diagnosis in group 1 and avascular necrosis of the femoral head in group 2. A femoral funnel-shaped type 1 according to Dorr was more frequent in group 2 (p=0.04). The same ceramic-on-ceramic uncemented THR was used in all cases. Screws for cup fixation were only used when strictly needed. We analysed the clinical results according to the Merle-D´Aubignè and Postel scale, the postoperative radiological reconstruction of the hip and the radiological appearance of cup loosening. Kaplan-Meier survivorship analysis was used to estimate the cumulative probability of not having a revision surgery. Results. Screw use required to obtain a secured interference fit of the acetabular component was found more frequently in group 1 (p=0.01). Postoperative pain (p=0.002) and function (p=0.002) were better in group 1. Mean acetabular abduction angle of the cup was greater in group 1 (p=0.03) and reconstruction to the hip rotation center according to Ranawat (p=0.01) was better in group 2. Placement of the acetabular component inside the Lewinnek´s zone and stem position were similar in both groups. No hips were revised due to complications related to ceramic or to stem loosening. Three cups were revised for aseptic loosening in group 1 and four in group 2. The survival rate for cup aseptic loosening at 15 years was 92.3% (95% CI: 83.7 to 100) for group 1 and 93.1% (95% CI: 85.3 to 99.9) for group 2 (Log rank, p=0.88). Conclusion. Ceramic-on-ceramic uncemented THR is an excellent option for young and very young patients. Despite worse preoperative conditions in patients under the age of 30 years, a similar clinical outcome was found in this series

Guidelines for the use of preoperative blood tests for elective surgery were established. However, there is less evidence and no guidelines regarding using these tests when a young, healthy patient undergoes minor orthopaedic trauma surgery. Bloodwork is often ordered routinely, regardless of medical history or the nature of the injury. We hypothesized that unnecessary blood work is requested for younger pre-operative patients, and their results will not change peri-operative management. This practice is not a judicious use of healthcare resources. This study aimed to evaluate the frequency, type, cost, and impact on clinical decisions if standard preoperative bloodwork was completed in healthy patients requiring surgical management of a minor fracture or dislocation. After the approval of our institutional ethics board, a retrospective chart review was conducted. Inclusion criteria were patients aged 18-60 years, who had an isolated minor orthopaedic trauma requiring outpatient surgery, who were American Society of Anesthesiologists (ASA) class 1. ASA class 1 is defined as “a normal healthy patient, without any clinically important comorbidity and without a clinically significant past/present medical history.” Data records from January 1, 2016, to December 31, 2018, were extracted from a provincial database (the Analytics Data Integration, Measurement and Reporting) for five hospitals. Data including demographics, surgical treatment, type and number of blood tests ordered, and ordering physician were collected. Any abnormal test results were checked to see whether they led to a change in patient management or related to a postoperative adverse event. Independent samples t-tests and Chi-square tests were used to compare the characteristics of patients who had preoperative bloodwork versus those who did not. The cost of preoperative blood work was estimated. During these two years, 627 patients met inclusion criteria, and 27% (n=168) of these patients had bloodwork completed pre-operatively, while only 34% (n=57) of these had one or more abnormal laboratory parameters. These abnormalities were minor and did not alter clinical management or result in repeated bloodwork peri-operatively. Patients who had bloodwork were significantly older (40.2 years) compared with patients without preoperative blood work (37.8 years; p=0.03), but there was no difference in sex between those who had bloodwork (53.4% male) and those who did not (51.4% male; p=0.63). The most common blood test ordered was a complete blood count, and the most commonly abnormal result was a mildly elevated white blood cell count (19%; n= 29). The most common patients to receive bloodwork were those with ankle (34%) and distal radius (34%) fractures. The bloodwork was primarily ordered by clinical associates (26%; n=46) and emergency department physicians (22%; n=38). Without considering lab personnel, consumables, and analysis time, the cost of this bloodwork was approximately $7685, an average of $45 per patient. Pre-operative bloodwork in young, healthy, asymptomatic patients requiring outpatient surgery for minor orthopaedic trauma had no clinical significance and did not change patient management. Rigorous prospective research is warranted to establish national guidelines for appropriate pre-operative bloodwork ordering to minimize unnecessary and costly investigations

Shoulder arthritis in the young adult is a deceptive title. The literature is filled with articles that separate outcomes based on an arbitrary age threshold and attempt to provide recommendations for management and even potential criteria for implanting one strategy over another using age as the primary determinant. However, under the age of 50, as few as one out of five patients will have arthritis that can be accurately classified as osteoarthritis. Other conditions such as post-traumatic arthritis, post-surgical arthritis including capsulorrhaphy arthropathy, and rheumatoid arthritis create a mosaic of pathologic bone and soft tissue changes in our younger patients that distort the conclusions regarding “shoulder arthritis” in the young adult. In addition, we are now seeing more patients with unique conditions that are still poorly understood, including arthritis of the pharmacologically performance-enhanced shoulder. Early arthritis in the young adult is often recognised at the time of arthroscopic surgery performed for other preoperative indications. Palliative treatment is the first option, which equals “debridement.” If the procedure fails to resolve the symptoms, and the symptoms can be localised to an intra-articular source, then additional treatment options may include a variety of cartilage restoration procedures that have been developed primarily for the knee and then subsequently used in the shoulder, including microfracture, and osteochondral grafting. The results of these treatments have been rarely reported with only case series and expert opinion to support their use. When arthritis is moderate or severe in young adults, non-arthroplasty interventions have included arthroscopic capsular release, debridement, acromioplasty, distal clavicle resection, microfracture, osteophyte debridement, axillary nerve neurolysis, and bicep tenotomy or tenodesis, or some combination of these techniques. Again, the literature is very limited, with most case series less than 5 years of follow-up. The results are typically acceptable for pain relief, some functional improvement, but not restoration to completely normal function from the patient's perspective. Attempts to resurface the arthritic joint have resulted in limited benefits over a short period of time in most studies. While a few remarkable procedures have provided reasonable outcomes, they are typically in the hands of the developer of the procedure and subsequently, other surgeons fail to achieve the same results. This has been the case with fascia lata grafting of the glenoid, dermal allografts, meniscal allografts, and even biologic resurfacing with large osteochondral grafts for osteoarthritis. Most surgical interventions that show high value in terms of improvement in quality of life require 10-year follow-up. It is unlikely that any of these arthroscopic procedures or resurfacing procedures will provide outcomes that would be valuable in terms of population healthcare; they are currently used on an individual basis to try to delay progression to arthroplasty, with surgeon bias based on personal experience, training, or expert opinion. Arthroplasty in the young adult remains controversial. Without question, study after study supports total shoulder arthroplasty over hemiarthroplasty once the decision has been made that joint replacement is the only remaining option

Introduction. Patient-specific instruments (PSI) and surgical-guiding templates are gaining popularity as a tool for enhancing surgical accuracy in the correction of oblique bone deformities Three-dimensional virtual surgical planning technology has advanced applications in the correction of deformities of long bones and enables the production of 3D stereolithographic models and PSI based upon a patient's specific deformity. We describe the implementation of this technology in young patients who required a corrective osteotomy for a complex three-plane (oblique plane) lower-limb deformity. Materials and Methods. Radiographs and computerized tomographic (CT) scans (0.5 mm slices) were obtained for each patient. The CT images were imported into post-processing software, and virtual 3D models were created by a segmentation process. Femoral and tibial models and cutting guides with locking points were designed according to the deformity correction plan as designed by the surgeon. The models were used for preoperative planning and as an intraoperative guide. All osteotomies were performed with the PSI secured in the planned position. Results. A total of 17 patients (9 males and 8 females, average age 14.7 years [range 8–24]) comprised the study group. All of the PSI were excellent fits for the planned bone surfaces during surgery. The osteotomies matched the preoperative planning simulation and allowed for easy fixation with pre-chosen plates. No intra- or postoperative complications were encountered. Surgery time was shortened (101 minutes) and intraoperative blood loose was less compared to historical cases. Clinical and radiographic follow-up findings showed highly satisfactory alignment of the treated extremities in all 17 patients. Conclusions. The use of 3D-printed models and patient-specific cutting guides with locking points increases accuracy, shortens procedure time, reduces intraoperative blood loss, and improves the outcome of osteotomies in young patients with complex oblique bone deformities

Total hip arthroplasty (THA) is effective, reproducible, and durable in the treatment of hip joint arthritis. While improvements in polyethylene materials have significantly reduced wear rates and osteolysis, aseptic loosening of implants remains one of the leading causes of revision THA. Additionally, fears of dislocation and instability have driven the increase in the utilization of larger diameter femoral heads in primary THA which can lead to increased wear when coupled with a polyethylene articulation. Finally, the increasing number of younger and active patients undergoing THA raises questions with regards to the ability of modern conventional bearings to provide durability and longevity beyond second and third decades following joint implantation. Ceramic-on-ceramic articulations are ideally suited for today's young and high demand patients undergoing primary THA. It has the lowest in-vitro wear properties of any bearing couple and the wear characteristics are further improved by its wettability and lubrication particularly when larger heads are utilised. Additionally, improvements in material properties and prosthesis design have significantly decreased fracture rates and increased the reliability of these implants. Furthermore, reported outcomes and longevity of modern ceramic-on-ceramic THAs in younger patients have all shown excellent survivorship despite patients achieving and maintaining a very high level of activity and function. In short, it is the bearing couple most in tune with current market demands and utilization trends. While registry data and meta-analyses of published literature have failed to show the superiority of ceramic-on-ceramic articulations compared to conventional bearings at 10 years, there is evidence that even highly crosslinked polyethylene (HXPE) is not immune to wear. Selvarajah et al. reported steady, in-vivo wear rates of HXPE exceeding 0.1mm/year threshold in young THA patients with 36mm ceramic ball heads. Additionally, small osteolytic lesions have been observed in hips with HXPE bearings at 12–14 years follow up. Finally, analysis of all controlled randomised studies have shown less osteolysis of ceramic-on-ceramic hips compared to polyethylene articulations. The significance of these lesions are unclear but the question remains: Can HXPE as a bearing be able to provide over 30 years of service needed to outlast patients younger than 60 years?. Concerns with cost, squeaking, and fractures do not make ceramic-on-ceramic bearings suitable for all patients undergoing primary THA. However, in young, healthy and active patients, a modern ceramic- on-ceramic articulation is most likely to provide the lowest wear rates, lowest risk of osteolysis, and greatest chance for life-long durability

Management of the young adult hip pathologies is a special entity in orthopaedic surgical practice that needs special emphasis and consideration. A wide range of pathological and traumatic conditions occur in the young adult hip that lead to functional disability and the development of premature osteoarthritis. Proper surgical interference when the hip is still in the pre-arthritic stage restores function to the young hip and protects it from early degenerative changes, and hence the anticipated need for future joint replacement surgery is prevented. Accurate estimation of the biomechanical error combined with careful understanding of the hip joint biology is the cornerstone of success of any hip preservation surgery ever performed to save the young adult hip. Safe surgical hip dislocation approach was adopted as one of the tools in the hands of the hip preservation surgeon to treat a broad spectrum of intra-articular hip pathologies like Perthes disease and severe forms of slipped capital femoral epiphysis (SCFE). Osteo-chondroplasty at the head-neck junction with relative femoral neck lengthening for Perthes disease, and Subcapital re-orientation of severe SCFE based on its retinacular vascular pedicle are often performed via the surgical hip dislocation approach. The approach is also useful with certain types of acetabular fractures that enables fixation of dual-column fractures via single approach with intra-articular visualization for the accuracy of reduction and hardware placement. The 4 cm mini-open direct anterior approach is ideal for the surgical treatment of cases with cam and/or pincer types of femoro-acetabular impingement. Peri-articular osteotomies performed either on the acetabular or the femoral sides of the hip joint are extremely useful in the correction of the biomechanical error that led to an existing hip pathology. Periacetabular osteotomies are commonly performed to treat dysplasia of the young hip. Proximal femoral osteotomies are commonly performed to treat a wide range of hip pathologies including non-unions of femoral neck fractures in the young adult. Correction of the biomechanical error at the proper timing ensures normalization of the hip joint loading conditions and range of motion that leads to reversal of the pathologic process and prevention of osteoarthritis. A hip joint replacement would have an unknown but certainly a finite life, whereas a young hip that has healed after hip preservation surgery would definitely last for a lifetime

Background. Because of the long life expectancy of young total hip arthroplasty (THA) patients and the limited durability of prosthetic implants in young patients, surgeon's always must take into account that the primary THA will be revised in the future. Therefore, not only the survival of the primary total hip in young patients is important, but we would also like to accentuate the revisability of a primary THA in this specific and high demanding patient population. Methods. Based on our philosophy, we always use cemented hip in young patients, if needed with acetabular bone impaction grafting. 343 consecutive cemented THA in 270 patients under the age of 50 years were evaluated, all implanted between 1988 and 2006. We also assessed the results of the revised THA (n=53) within the same population. Clinical, radiographical and survival of primary and revision THA were evaluated. Outcome. Survival analysis of all 343 hips with endpoint revision for any reason of either component showed a survival of 86% after 10 years. Survival of the stem and cup with endpoint aseptic loosening 93% after 10 years. Remarkably, the THA in which the cemented cup was combined with acetabular bone impaction grafting had a survival of 90% (SE 2.8) in contrast to a survival of 82% (SE 3.4) of the cups without an acetabular revision with endpoint revision for any reason of the whole prostheses(log-rank test, p=0.156) at 10 years. With no patient lost during follow-up, 53 primary hips were revised after a mean follow-up of 8.9 (range 2.0–19.3) years. The average follow-up of the revision THA was 4.2 (range 0.1–14.8) years. Three hips of this revision cohort needed a repeat revision, two had a reinfection after a septic revision and one revised cup failed 12 years after revision. The survival of the revised cohort with endpoint revision for any reason was 91% after 5 years, with endpoint aseptic loosening the survival at 5 years was 100 %. As well after primary as revision THA good clinical outcome scores were measured. Interpretation. Cemented implants in young patients showed satisfying results in primary as well as after revision THA with very acceptable survival and clinical outcomes. Keeping in mind that the young patient will outlive their primary THA, the primary hip has to be revisable and the results of the revision THA must be as good as the primary THA. Bone defects both in primary and revision THA can be successful managed with impacted bone grafts, without the need for augments, cages or larger implants

90% of young patients that develop DJD of the hip have an underlying structural problem, most frequently hip dysplasia. The structural problem results in decreased contact area, increased contact stresses about the anterior and lateral acetabulum and femoral head and results in labral pathology, early cartilage damage and if left untreated leads to end stage hip arthritis. Despite the optimism of alternative bearing surfaces and highly cross linked polyethylene, THA should still be discouraged in young patients. Many patients with symptomatic hip dysplasia in the absence of arthritis will benefit from joint preservation. The goal of treatment should be restoration of anatomy as close to normal as possible. The Bernese PAO is the preferred technique in many centres in North America and Europe because of its balance between minimal exposure, complications, and ability to provide optimal correction. The ideal patient for a PAO is young, has no arthritis, is not obese (BMI <30) and has poorly covered femoral head where congruency is possible. A PAO has advantages over other osteotomies and include: . 1). Performed through one incision without violation of the abductors. 2). Pelvic ring and an outlet, are not disrupted. 3). Posterior column is preserved. 4). Allow multidirectional correction. 5). Can perform capsulotomy to assess the labrum and check for impingement. The results of the osteotomy have been encouraging with up to 60% survivorship free from total hip arthroplasty at 20 years. Most studies show improvement in pain and function, improvement in radiographic coverage of the femoral head with no improvement in range of motion. Treatment should be individualised to each patient based on radiographic findings, age and cartilage status and restoration of anatomy as close to normal as possible should be the ideal treatment, most commonly in the form of a periacetabular osteotomy

Introduction. Total hip arthroplasty (THA) is becoming a common procedure because it dramatically relieves the patient's pain. Accordingly, young patients who hope to take THAs are also increasing. The results of THAs in the young patients have historically shown relatively poor survivorship. However several improvements of components may promise good long term results in active young patients. There was no consensus about the appropriate time for performing THA. The purpose of this study is to review the results of THAs younger than 40 years. Material and methods. A retrospective review of 14 primary THAs in 12 patients was conducted. The mean age was 27.0 (range 17–30). Ten were female (83%) and 2 were male (17%). The average follow –up period was 38.3 months (range 18–64). All operations were performed using direct anterior approach (DAA). All patients were allowed full weight bearing as tolerated in the immediate postoperative periods. All were cementless THA and the articulation bearing were ceramic/ceramic in 5 hips (33.3%), metal/highly cross linked polyethylene in 8 hips (53.3%), and ceramic/ highly cross linked polyethylene in 2 hips (13.3%). All patients were followed clinically and radiographically. Patients were evaluated at 4,6,12 weeks and each year postoperatively. Patients were allowed sports at 3 months postoperatively without limitations. Results. The underlying etiology was steroid-induced osteonecrosis in 5 patients, alcohol-induced osteonecrosis in 2 patients, developmental dysplasia in 2 patients (1 post osteotomy and 2 conservative therapy), infection in 1 patients, ankylosing spondylitis in 1 patients, and epiphyseal dysplasia in 1 patients. All patients failed conservative treatment. Two patients had prior osteotomy surgeries. Preoperative average JOA score, which is 100 points in full score, was 45 points. Those scores improved to 99 points post operatively. All patients became to walk without any assistive devices. There were no infections and dislocations. Their radiographs showed no loosening, subsidence, and osteolysis. All of their radiographs showed well fixed osseous integrations. Discussion and conclusion. Although our patients were very small numbers and follow up periods were not long, all of our patients showed good clinical and radiological results. When conservative treatments failed to relieve their pain, surgical treatments are required to restore their highly active lives. The modern THA has been showed numerous good results in older generations. With modern implants and surgical technique, we can also expect promising results in young patients under the condition with careful and long term follow-up

Acetabular fractures, particularly in the geriatric population are on the rise. A recent study indicated a 2.4-fold increase in the incidence of acetabular fractures, with the fastest rising age group, those older than the age of 55. Controversy exists as to the role and indications for total hip arthroplasty (THA), particularly in the acute setting. Three common scenarios require further evaluation and will be addressed. 1.) What is the role of THA in the acute setting for young patients (< 55 years old)? 2.) What is the role and indications for THA in the older patient population (>55 years) and what are surgical tips to address these complex issues? 3.) What are the outcomes of THA in patients with prior acetabular fractures converted to THA?. Acetabular fractures in young patients are often the result of high energy trauma and are a life changing event. In general, preservation of the native hip joint and avoidance of arthroplasty as the first line treatment should be recommended. A recent long-term outcome study of 810 acetabular fractures treated with Open Reduction and Internal Fixation (ORIF) demonstrated 79% survivorship at 20 years with need for conversion to THA as the endpoint. Risk factors for failure were older age, degree of initial fracture displacement, incongruence of the acetabular roof and femoral head cartilage lesions. In selected younger patients, certain fracture types with concomitant injuries to articular surfaces may best be treated by acute THA. In the elderly patient population, acetabular fractures are more likely the result of low energy trauma but often times result in more displacement, comminution and damage to the articular surface. Osteoporosis and generalised poor bone quality make adequate reduction and fixation a challenge in these acute injuries. As such, the role of acute arthroplasty is becoming more widespread. Consideration should be given to delayed arthroplasty in certain patients to allow time for fracture healing followed by THA. However, early mobilization and weight bearing is important in the elderly population and consideration should be given to acute THA. The challenge remains gaining appropriate acetabular fixation in the fractured, osteoporotic bone. Early results showed high complication rates with acetabular fixation. However, newer fixation surfaces and advances in ORIF techniques have led to improved results. In addition, the need for complex acetabular reconstruction with the use of cages or cup cage constructs may be required in this setting. Appropriate 3-D imaging is essential to evaluate the extent of involvement of the anterior and posterior columns as well as the acetabular walls. Mears et al. reported on 57 patients who underwent THA for acute acetabular fracture and reported results at a mean of 8.1 years. 79% of patient reported good or excellent results and no acetabular cups were revised for loosening. One of the more common scenarios is the patient that presents with a prior ORIF of an acetabular fracture that has developed post-traumatic arthritis or avascular necrosis of the hip and requires conversion to THA. Challenges in this patient population include dealing with prior hardware that may interfere with THA component fixation, severe stiffness of the joint making exposure difficult and prior heterotopic ossification that may put neurovascular structures at risk. Previous studies have demonstrated lower long-term survivorship of the acetabular component (71% at 20 years) compared to primary THA for osteoarthritis. New acetabular fixation surfaces should mitigate the risk of aseptic loosening in this challenging patient population

Introduction:. Hard-on-hard bearings and surface replacement (SR) have been used in young and active patients due to the reduced wear and lower rates of osteolysis. However, neither of these options resulted in survivorship higher than 90%–95% in this group of patients. The purpose of this prospective study was to compare minimum 10-year survivorship of non-cemented total hip arthroplasty (THA) using 28 mm metal head against highly-cross linked polyethylene (HXLPE) in our cohort as compared to published reports of other bearings, including surface replacements, in young-active patients. Matierial and Methods:. From 1999 to 2003, 91 consecutive patients (112 hips; 57 males and 34 females) with average UCLA score of 8 and mean age 53 years (range 24–65 years), who received metal on HXLP (Crossfire), were included. At minimum 10-years follow-up, patients' clinical data was assessed. All level I, II studies, registry data, and prospective cohorts published in the literature with minimum 10 years of surface replacement (SR) and ceramic on ceramic (CoC) in young patients were included. Results:. There were no revisions for fracture, osteolysis or loosening. There were 2 revisions: one periprosthetic infection and one chronic dislocation. Kaplan-Meier survivorship was 97% for all cause failures and 100% for wear-related failures. In review of the literature, the 10-year results of metal on HCLPE in young patients as well as the registry data were similar or better than SR and CoC. Discussion and Conclusion:. This study demonstrates that 28 mm metal head on HXLPE has lower revision rates as compared to other bearings and surface replacement in the published literature at a minimum 10-year follow-up in young-active patients, without the limitations of heard-on-heard bearings. This bearing should be considered as the gold standard for young and middle age patients. Oxidation of Crossfire is an overly stated limitation

Traditionally, arthritis is a disease which generally affects the elderly population. However, the incidence in young patients is well described and is increasing with the ever-growing obese population. Currently, the non-surgical treatment of osteoarthritis consists of corticosteroid injections, hyaluronic acid injections, weight loss, physical therapy, bracing, orthotics, narcotics, and non-steroidal anti-inflammatory drugs (NSAIDS). Oral medications (NSAIDS, tramadol, and opioids) can provide effective pain relief. Improvement with NSAIDs has been reported to be 20% relative to baseline, with better improvements seen with selective cox-2 inhibitors, which also have reduced gastrointestinal and renal toxicity. Additionally, the recent AAOS guidelines strongly recommend using NSAIDs or tramadol for pain relief. Although narcotics are effective analgesics, their use in young arthritic patients can potentially predispose individuals to future opioid dependency, and thus should be used sparingly. The primary purpose of physical therapy is to improve range of motion, strengthen muscles, and improve proprioception. Currently, the AAOS strongly recommends that patients undergo self-management programs, strengthening, low-impact aerobic exercises, and neuromuscular education. Similarly, they moderately recommended that patients with a BMI ≥ 25 undergo weight loss for symptomatic arthritis. Bracing options consist of the following: off-loader braces and transcutaneous nerve stimulation braces. These work to either off-load pressure in the knee or to scramble small nerve pain sensation, respectively. Corticosteroid injections are used to minimise pain and reduce inflammation in the joint associated with arthritis. However, their long-term repetitive use in young patients is not recommended, and current AAOS guidelines are inconclusive on their effectiveness. Additionally, the AAOS guidelines strongly recommend against the use of acupuncture, glucosamine/chondroitin, and hyaluronic acid injections

Introduction. Osteoarthritis (OA) represents a leading cause of disability and a growing burden on healthcare budgets. OA is particularly vexing for young, active patients who have failed less invasive therapies but are not ideal candidates for HTO or arthroplasty. Often, patients suffering in this wide therapeutic gap face a debilitating spiral of disease progression, increasing pain, and decreasing activity until they become suitable arthroplasty patients. An implantable unloading device was evaluated for the treatment of medial knee OA in this patient population. Joint overload has been cited as a contributor to OA onset or progression. In response, the KineSpring® System (Moximed, Inc, USA) has been designed to reduce the load acting on the knee. The unloader is implanted in the subcutaneous tissue without violating the joint capsule, thus preserving the option of future primary arthroplasty. The implant may be particularly useful for young, active patients, given the reversibility of the procedure and the preservation of normal flexibility and range of motion. Methods and Results. The KineSpring System was implanted in 79 patients with isolated medial knee OA, and the longest duration exceeds two and a half years. Treated patients were young and obese (mean age: 52 years, range 32–75; mean BMI: > 30 kg/m. 2. , range 21–45). Acute implant success, adverse events, and clinical outcomes using validated patient reported outcomes tools were recorded at baseline, post-op, 2 and 6 weeks, and 3, 6, 12 and 24 months post-op. All centers received ethics committee approvals prior to enrolling patients in the study. Mean surgical time was 72 min (range 45–153 minutes), and all patients were discharged after a few days. Patients recovered rapidly, achieving full weight bearing within 1–2 wks and normal range of motion by 6 weeks. Most patients experienced significant pain relief and functional improvement by six weeks, with results sustained beyond the two-year follow-up visit. WOMAC Pain improved from 43 at baseline to 13 at 2 years (p<0.001), WOMAC Function improved from 43 at baseline to 11 at 2 years (p<0.001), and WOMAC Stiffness improved from 52 at baseline to 18 at 2 years (p<0.001). Patients reported satisfaction with implant and its appearance. Conclusions. The KineSpring System provided pain relief and functional improvement in a young and obese patient population that may not be ideal for HTO or arthroplasty. This unloading device, with these successful results, fills a major gap in treatment options for young and active OA patients

The most appropriate bearings in young patients remain highly debated. The aim of this metaanalysis was to summaries the best available evidence on relative success of the three most popular bearings [metal-on-poly (MOP), metal-on-metal (MOM) and ceramic-on-ceramic (COC)] used in total hip replacement (THR) in young active patients. All the relevant studies published in the English language were retrieved. Studies with THR in patients with mean age less than 55 years of age were selected. The survivorship analysis for the three important bearings at 10 years was evaluated. Ten-year survival rates suggest that MOM bearings performed significantly better than MOP (p=0.01) and COC (p=0.001). MOP revealed higher survival rates than COC bearings (p=0.05). Our findings support the use of MOM bearings in the management of the young arthritic hip. These findings, largely based upon observational studies should be taken in context to the limitations of such non-randomized study designs

Abstract

Cemented total hip arthroplasty (THA) in the younger patient has historically been associated with higher wear and revision rates. We carried out a retrospective study of a prospectively collected database of patients at Wrightington hospital undergoing cemented THA under 55 years of age to determine acetabular wear and revision rates.

Between August 2005 and December 2021 a cohort of 110 patients, 56 males and 54 females, underwent Cemented Total Hip Replacement through a posterior approach. Mean age at operation was 50yrs (35–55). The mean follow up was 6 years 9 months (0–16 years). 3 patients were lost to follow-up. Of the remaining 107 patients, Conventional and cross lined polyethylene were used in 54 and 53 patients respectively. Ceramic heads were used in 102 patients. 22.225mm and 28mm heads were used in 60 and 47 patients respectively. Clinical outcomes were assessed by Merle d'Aubigne and Postel scores which showed significant functional improvement. Linear wear was measured on plain radiographs using TRAUMA CAD and cup loosening was assessed by classification of Hodgkinson et al.

No cases were revised during the observed follow up period. The mean wear rate in conventional and crosslinked polyethylene cups were 2.31mm (0.1–4.6) and 1.02mm (0.1–2.6) respectively.

Cemented THA with both conventional and crosslinked polyethylene provides excellent survival rates in adults under the age of 55 years and crosslinked polyethylene may further improve these results due to improved wear rates.

Treatment of the femoral head necrosis with severe extensive collapse in young adults and adolescents are still challenging. We thought preserve the joint and bone stock were important factor for the treatment of femoral head necrosis in young patients. We reviewed the posterior rotational osteotomy for younger patients with severe osteonecrosis. The advantages of posterior rotational osteotomy are; the necrotic area is moved to non-weight bearing portion. The posterior column artery is shifted medially without vascular damage by rotation. Postoperative uncollapsed anterior viable areas are moved to the loaded portion below the acetabular roof in flexed positions. Eighty five hips of 66 young adults (less than 50 years old, mean age; 31 years) with extensive necrosis treated by posterior rotational osteotomy were reviewed with more than 5 year follow up with a mean of 9 years. Results of 13 hips of 12 adolescents (mean age; 14 years) with extensive collapsed necrosis treated by this procedure were also studied with a mean of 6.5 years. A mean degree of posterior rotation was 121. Recollapse was prevented in 77 hips (91%) of adults, and all 13 hips of adolescents on final AP radiographs. Collapsed lesion was remodeled well and resphericity of the postoperative transferred medial collapsed femoral head on final AP radiographs was observed. However, some of the cases were out of indication of the joint preserving procedure showing extensive lesion. In these cases, we performed the MAYO conservative stem for preserving bone stock. Radiological results of 26 hips with osteonecrosis treated by MAYO stem (mean age 42 years, minimum 5 year follow-up. mean; 6.7 years) showed that 2 mm subsidence in one, osteointegration of zone 2, 6 in 93%, no entire lucent line. No hips were revised for late loosening associated with osteolysis. CT imaging indicated that spot welds of zone 2, 6 were found in 100ï¼ï¿½, stress shielding of zone 1, 5 (23.5ï¼ï¿½). These operations were useful particularly for younger patients

Purpose. Unicompartmental Knee Arthroplasty (UKA) has been indicated for inactive elderly patients over 60, but for young and active patients less than 60 years old, it has been regarded as a contraindication. The purpose of this study is to evaluate the usefulness of UKA performed on young Asian patients under 60 years of age by analyzing clinical outcomes, complications and survival rate. Materials and Methods. The subjects were 82 cases, which were followed up for at least 5 years (from 5 to 12 years). Only Oxford phase III® (Biomet Orthopedics, Inc, Warsaw, USA) prosthesis was used for all cases. The clinical evaluation was done by the range of motion, Knee society score (KSS), WOMAC score. The radiographic evaluation was performed on weight bearing long-leg radiographs, AP and lateral view of the knee and skyline view of the patella. The survival rate was estimated by Kaplan-Meier survival analysis. Results. Three bearing dislocations, one medial tibial collapse and one lateral osteoarthritis occurred, so the complication rate was 6.1% (5/82). Among the 3 cases of bearing dislocation, 2 cases were resolved by replacing with a thicker bearing and 1 case was converted to TKA due to repeated dislocation. One case of medial tibia collapse and one lateral osteoarthritis were converted to total knee arthroplasty (TKA). All clinical outcomes measured by KSS scores and WOMAC score showed a statistically significant difference (p<0.001). The 10 year cumulative survival rate using Kaplan-Meier survival method was 94.7% (95% CI: 88.7%–100%). Conclusion. The clinical outcomes and the survival rate of young asian patients less than 60 years of age who underwent Oxford medial UKA showed good clinical results and a good survival rate in the mid-term results. However, long-term follow-up is needed for more reliable clinical results

Introduction:. Total hip arthroplasty has became one of the most successful standard procedures in the orthopaedic surgery. With a more frequent use in young and active patients bone saving procedures become more important. On the other hand, the ever increasing trend toward minimal excision of the healthy bone during implantation of the total hip replacement has led to a range of implants that can be classified according their means of anchorage in the various anatomic segments. The Nanos-short-stem endoprothesis presented here requires metaphyseal anchorage. Material and methods:. From juli 2005 to march 2009 a total of 112 (70 males, 52 female) uncemented Nanos-short-stem prothesis were implanted in 111 patients in Westpfalz academic hospital –University Mainz. The patiens average age was 53 years (33–73). The indication for this procedure was predominantly coxarthrosis. In all cases dorsal approach was used. The mean follow up period was 2,5 years (range 6 months–4,5 years). The patients were assessed using Harris Hip Score and radiologically to detect any bone changes, the stand of the prothesis and peri-articular ossifications. Results:. The perioperative Harris Hip Score was 53 (28–77), postoperative was 94 (86–100). We did not have discovered any prothesis specific complications. Radiological follow up examinations showed the development of increasing trabecular reinforciment of the femoral neck and pertrachanteric regions. There is no evidence of any loosing or migration of the prothesis. Conclusion:. the stem design of Nanos-short-stem prothesis allowed a metaphyseal intertrochanteric multipoint primary fixation. The surgical technique is simple. It offers alternative to convenential total hip arthroplasty especially in young patients and save bone stock for later revision (1–2). Long term studies still be needed

The surgical treatment of young adults with end-stage hip disease has been a challenge. Inferior THA survival in the young, perceived advantages of hip resurfacing versus THA and advancements in tribology, led to the introduction of 3rd generation Metal-on-Metal-Hip-Resurfacing-Arthroplasty (MoMHRA). To-date, thousands of such prostheses have been implanted worldwide in younger patients, yet little is known regarding long-term outcome. The only studies reporting greater than 10 year outcome come from designer centres with survivorship varying between 88.5–96% at 12 years. Arthroplasty Registries (AR) have reported less favourable survivorships with female gender and size having a negative effect on survival. In our independent hip resurfacing centre in Ghent, Belgium, a single surgeon has implanted more than 3500 HRA over more than 12 years. A cohort of 149 patients who received a Birmingham Hip Resurfacing (BHR) at a mean age of 50 years at surgery have now reached a minimum 10 years follow-up. The overall 12-year survival in these young adults is 93.1% (95% CI: 88.3–98.0), 99% in males and 87.3% in females. These survivorship data are superior to registry reported figures of THA amongst young patients and correspond well with previous reports from designer centres. The long-term survivorship and clinical outcome of the BHR are excellent in men, uninfluenced by preoperative diagnosis or age. However, survivorship in women is inferior and usually related to increased wear and reactions to metal debris. Malpositioning of components with associated wear-induced soft tissue fluid collections is the most frequent factor leading to failure of a HRA. In our experience, mid-term outcome following revision is good and complication and re-revision rates can be low. Surgical experience, early intervention in cases of mal-positioned implants, clinical use of ion levels, implantation of larger ceramic-on-ceramic THA femoral heads and patient education are factors in improving outcome and reducing complication and re-revisions following HRA revision

Ceramic-on-ceramic (COC) bearing surfaces have consistently demonstrated reliable clinical results with when coupled with appropriated designed femoral stems and acetabular shells. Ceramic bearing surfaces are highly wettable and display both boundary and hydrodynamic fluid-film lubrication modes, which lead to extremely low wear rates. Furthermore, COC bearing couples have been shown to exhibit virtually no risk of adverse biologic reaction and have not been associated with corrosion-induced adverse tissue reactions that occur with metal taper junctions, particularly head-neck taper junctions. The relative brittleness of ceramics initially was thought to be a major disadvantage; however, four decades of improvement in the manufacture of ceramics and rigorous proof testing has led an extremely low risk of fracture, perhaps lower than that for cross-linked polyethylene. More recently it has become increasing appreciated that nearly all revisions for squeaking have been restricted to specific designs and materials, including the use of a titanium elevated metal rim on the acetabular side, and more flexible femoral components made of a beta-titanium alloy (TMZF) which had thin necks and relative small tapers. Multiple clinical studies document excellent long-term survival of COC bearing couples in young patients with revision for any reason as the primary endpoint. Our own experience with 341 hips with 2 to 15 and average 9.1 year f/u demonstrates a 95% overall survivorship (revision for any reason) at 13 years in patients under 50 years of age at the time of surgery. By contrast, cross-linked polyethylene bearings have not been studied so carefully and have not been shown to be superior to ceramic-ceramic bearings in young patients. These bearing surfaces represent a very heterogeneous group of products, with varying degrees of cross-linking, post-irradiation processing methods, and additives. Cross-linked polyethylenes in general have a lower fatigue strength than conventional polyethylene and are prone to fracture, especially when thin material is subjected to high stress. Some types of cross-linked polyethylenes are prone to in vivo oxidation, leading to further mechanical compromise over time. Studies also demonstrate the absence of reduction in femoral head penetration or risk of osteolysis in heads 32mm and larger, which are commonly used today. The most recent cross-linked polyethylene products have the least clinical support for their use. The long-term biologic effects of the smaller HXLPE wear particles and newer additives, including the more recently added vitamin E compounds are unknown. Indeed, in vitro, the debris has been shown to be cytotoxic. There is a paucity of survivorship data for hips utilising HXLPE, especially in younger, more active individuals. For these reasons, we believe that the ceramic-ceramic bearings are the gold standard for THA in the young patient and that cross-linked polyethylene bearing are being continually changed and have little long term clinical outcomes data to support their use