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Bone & Joint Research
Vol. 11, Issue 5 | Pages 270 - 277
6 May 2022
Takegami Y Seki T Osawa Y Imagama S

Aims. Periprosthetic hip fractures (PPFs) after total hip arthroplasty are difficult to treat. Therefore, it is important to identify modifiable risk factors such as stem selection to reduce the occurrence of PPFs. This study aimed to clarify differences in fracture torque, surface strain, and fracture type analysis between three different types of cemented stems. Methods. We conducted biomechanical testing of bone analogues using six cemented stems of three different types: collarless polished tapered (CPT) stem, Versys Advocate (Versys) stem, and Charnley-Marcel-Kerboull (CMK) stem. Experienced surgeons implanted each of these types of stems into six bone analogues, and the analogues were compressed and internally rotated until failure. Torque to fracture and fracture type were recorded. We also measured surface strain distribution using triaxial rosettes. Results. There was a significant difference in fracture torque between the three stem types (p = 0.036). Particularly, the median fracture torque for the CPT stem was significantly lower than that for the CMK stem (CPT vs CMK: 164.5 Nm vs 200.5 Nm; p = 0.046). The strain values for the CPT stem were higher than those for the other two stems at the most proximal site. The fracture pattern of the CPT and Versys stems was Vancouver type B, whereas that of the CMK stem was type C. Conclusion. Our study suggested that the cobalt-chromium alloy material, polished surface finish, acute-square proximal form, and the absence of a collar may be associated with lower fracture torque, which may be related to PPF. Cite this article: Bone Joint Res 2022;11(5):270–277


The Bone & Joint Journal
Vol. 101-B, Issue 7 | Pages 779 - 786
1 Jul 2019
Lamb JN Baetz J Messer-Hannemann P Adekanmbi I van Duren BH Redmond A West RM Morlock MM Pandit HG

Aims. The aim of this study was to estimate the 90-day risk of revision for periprosthetic femoral fracture associated with design features of cementless femoral stems, and to investigate the effect of a collar on this risk using a biomechanical in vitro model. Materials and Methods. A total of 337 647 primary total hip arthroplasties (THAs) from the United Kingdom National Joint Registry (NJR) were included in a multivariable survival and regression analysis to identify the adjusted hazard of revision for periprosthetic fracture following primary THA using a cementless stem. The effect of a collar in cementless THA on this risk was evaluated in an in vitro model using paired fresh frozen cadaveric femora. Results. The prevalence of early revision for periprosthetic fracture was 0.34% (1180/337 647) and 44.0% (520/1180) occurred within 90 days of surgery. Implant risk factors included: collarless stem, non-grit-blasted finish, and triple-tapered design. In the in vitro model, a medial calcar collar consistently improved the stability and resistance to fracture. Conclusion. Analysis of features of stem design in registry data is a useful method of identifying implant characteristics that affect the risk of early periprosthetic fracture around a cementless femoral stem. A collar on the calcar reduced the risk of an early periprosthetic fracture and this was confirmed by biomechanical testing. This approach may be useful in the analysis of other uncommon modes of failure after THA. Cite this article: Bone Joint J 2019;101-B:779–786


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_1 | Pages 14 - 14
1 Jan 2018
Russell R Nwelue E Schell B Huo M
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Modular tapered stems have become increasingly popular in femoral revisions and stem subsidence remains a reported clinical problem. Computer modeling and biomechanical testing demonstrated a minimum initial line-to-line fit of 25 mm was required to reduce the risk of subsidence. We examined XR imaging of 110 consecutive femoral revisions by a single surgeon using two different modular tapered stems to determine if this biomechanical threshold was of clinical relevance. 72% of the revisions were done for aseptic loosening and 28% for periprosthetic fracture or infection. Stem subsidence of any degree was observed in 24 (21.8%), while 12 (10.9%) demonstrated substantial subsidence of > 10 mm. We matched this cohort to 12 patients who had no stem subsidence. The average age of patients with subsidence was 59 years (43 to 79 years). The average of patients without subsidence was 66 years (41 to 77 years). Each group had 7 men and 5 women. Stem subsidence was observed in the first 3 months post-surgery. The demographics, bone deficiency, stem design, and stem diameter were similar between groups. 83% of patients with substantial stem subsidence had less than 25 mm of line-to-line fit compared to 17% of patients without subsidence. The 12 cases of no stem subsidence had a mean line-to-line fit of 48 mm (25 to 55 mm). 75% of patients with substantial stem subsidence had also undergone an extended trochanteric osteotomy (ETO) compared to 33% of patients without subsidence. We conclude that there is a positive correlation with the biomechanical testing parameters and substantial stem subsidence. ETO was found to be associated with higher stem subsidence


Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_6 | Pages 30 - 30
1 May 2019
Lamb J Baetz J Messer-Hannemann P Redmond A West R Morlock M Pandit H
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Background. Post-operative periprosthetic femoral fractures (PFF) are a devastating complication associated with high mortality and are costly. Few risk factors are modifiable apart from implant choice. The design features governing risk of PFF are unknown. We estimated the 90-day risk of revision for PFF associated with design features of cementless femoral stems and to investigate the effect of a collar on early PFF risk using a biomechanical in-vitro model. Patients, materials and methods. 337 647 primary THAs from the National Joint Registry (UK) were included in a multivariable survival and regression analysis to identify the adjusted hazard of PFF revision following primary THA using cementless stems. The effect of a collar in cementless THA on early PFF was evaluated in an in-vitro model using paired fresh frozen cadaveric femora. Results. Prevalence of PFF revision was 0.34% (1180/337647) and 44.0% occurred (520/1180) within 90 days of surgery. Implant risk factors included: collarless stem, non grit-blasted finish and triple tapered design. In the in-vitro PFF model a medial calcar collar consistently improved construct stability and fracture resistance. Discussion. During rotational injury the collar can load the calcar in compression increasing the force required for a fracture. This increases the force required to cause a PFF around a collared implant versus collarless implants. The calcar possibly acts as a check-rein which prevents excessive peri-prosthetic trabecular deformation in rotational injuries and may improve the resistance to loosening after high energy injuries which do not cause cortical fracture. Conclusion. Analysis of stem design features in registry data is a useful method to identify implant characteristics which affect the risk of early PFF around cementless femoral stems. Calcar collar reduced early PFF risk and this was confirmed by biomechanical testing. This approach may be useful in the analysis of other uncommon arthroplasty failure modes


Bone & Joint Open
Vol. 2, Issue 7 | Pages 466 - 475
8 Jul 2021
Jain S Lamb J Townsend O Scott CEH Kendrick B Middleton R Jones SA Board T West R Pandit H

Aims

This study evaluates risk factors influencing fracture characteristics for postoperative periprosthetic femoral fractures (PFFs) around cemented stems in total hip arthroplasty.

Methods

Data were collected for PFF patients admitted to eight UK centres between 25 May 2006 and 1 March 2020. Radiographs were assessed for Unified Classification System (UCS) grade and AO/OTA type. Statistical comparisons investigated relationships by age, gender, and stem fixation philosophy (polished taper-slip (PTS) vs composite beam (CB)). The effect of multiple variables was estimated using multinomial logistic regression to estimate odds ratios (ORs) with 95% confidence intervals (CIs). Surgical treatment (revision vs fixation) was compared by UCS grade and AO/OTA type.


Bone & Joint Research
Vol. 9, Issue 9 | Pages 534 - 542
1 Sep 2020
Varga P Inzana JA Fletcher JWA Hofmann-Fliri L Runer A Südkamp NP Windolf M

Aims

Fixation of osteoporotic proximal humerus fractures remains challenging even with state-of-the-art locking plates. Despite the demonstrated biomechanical benefit of screw tip augmentation with bone cement, the clinical findings have remained unclear, potentially as the optimal augmentation combinations are unknown. The aim of this study was to systematically evaluate the biomechanical benefits of the augmentation options in a humeral locking plate using finite element analysis (FEA).

Methods

A total of 64 cement augmentation configurations were analyzed using six screws of a locking plate to virtually fix unstable three-part fractures in 24 low-density proximal humerus models under three physiological loading cases (4,608 simulations). The biomechanical benefit of augmentation was evaluated through an established FEA methodology using the average peri-screw bone strain as a validated predictor of cyclic cut-out failure.


Bone & Joint Research
Vol. 6, Issue 1 | Pages 8 - 13
1 Jan 2017
Acklin YP Zderic I Grechenig S Richards RG Schmitz P Gueorguiev B

Objectives

Osteosynthesis of anterior pubic ramus fractures using one large-diameter screw can be challenging in terms of both surgical procedure and fixation stability. Small-fragment screws have the advantage of following the pelvic cortex and being more flexible.

The aim of the present study was to biomechanically compare retrograde intramedullary fixation of the superior pubic ramus using either one large- or two small-diameter screws.

Materials and Methods

A total of 12 human cadaveric hemipelvises were analysed in a matched pair study design. Bone mineral density of the specimens was 68 mgHA/cm3 (standard deviation (sd) 52). The anterior pelvic ring fracture was fixed with either one 7.3 mm cannulated screw (Group 1) or two 3.5 mm pelvic cortex screws (Group 2). Progressively increasing cyclic axial loading was applied through the acetabulum. Relative movements in terms of interfragmentary displacement and gap angle at the fracture site were evaluated by means of optical movement tracking. The Wilcoxon signed-rank test was applied to identify significant differences between the groups


The Bone & Joint Journal
Vol. 97-B, Issue 9 | Pages 1214 - 1219
1 Sep 2015
Loh BW Stokes CM Miller BG Page RS

There is an increased risk of fracture following osteoplasty of the femoral neck for cam-type femoroacetabular impingement (FAI). Resection of up to 30% of the anterolateral head–neck junction has previously been considered to be safe, however, iatrogenic fractures have been reported with resections within these limits. We re-evaluated the amount of safe resection at the anterolateral femoral head–neck junction using a biomechanically consistent model.

In total, 28 composite bones were studied in four groups: control, 10% resection, 20% resection and 30% resection. An axial load was applied to the adducted and flexed femur. Peak load, deflection at time of fracture and energy to fracture were assessed using comparison groups.

There was a marked difference in the mean peak load to fracture between the control group and the 10% resection group (p < 0.001). The control group also tolerated significantly more deflection before failure (p < 0.04). The mean peak load (p = 0.172), deflection (p = 0.547), and energy to fracture (p = 0.306) did not differ significantly between the 10%, 20%, and 30% resection groups.

Any resection of the anterolateral quadrant of the femoral head–neck junction for FAI significantly reduces the load-bearing capacity of the proximal femur. After initial resection of cortical bone, there is no further relevant loss of stability regardless of the amount of trabecular bone resected.

Based on our findings we recommend any patients who undergo anterolateral femoral head–neck junction osteoplasty should be advised to modify their post-operative routine until cortical remodelling occurs to minimise the subsequent fracture risk.

Cite this article: Bone Joint J 2015;97-B:1214–19.


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 1 | Pages 19 - 25
1 Jan 2006
Scheerlinck T de Mey J Deklerck R Noble PC

Using a modern cementing technique, we implanted 22 stereolithographic polymeric replicas of the Charnley-Kerboul stem in 11 pairs of human cadaver femora. On one side, the replicas were cemented line-to-line with the largest broach. On the other, one-size undersized replicas were used (radial difference, 0.89 mm sd 0.13).

CT analysis showed that the line-to-line stems without distal centralisers were at least as well aligned and centered as undersized stems with a centraliser, but were surrounded by less cement and presented more areas of thin (< 2 mm) or deficient (< 1 mm) cement. These areas were located predominantly at the corners and in the middle and distal thirds of the stem. Nevertheless, in line-to-line stems, penetration of cement into cancellous bone resulted in a mean thickness of cement of 3.1 mm (sd 0.6) and only 6.2% of deficient and 26.4% of thin cement. In over 90% of these areas, the cement was directly supported by cortical bone or cortical bone with less than 1 mm of cancellous bone interposed.

When Charnley-Kerboul stems are cemented line-to-line, good clinical results are observed because cement-deficient areas are limited and are frequently supported by cortical bone.