Preliminary results confirmed that the use of platelet gel and packed medullary cells as adjuvant for the lyophilized bone aid bone repair and graft integration. Morphological and morphometric tests showed that at six week the newly formed bone of group 3 had better mechanical properties. This study shows that the use of platelet gel and packed autologous medullary cells combined with lyophilized bone chips produces a faster and mechanically stronger recovery of bone stock in the treatment of bone defects.