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The Bone & Joint Journal
Vol. 101-B, Issue 11 | Pages 1408 - 1415
1 Nov 2019
Hull PD Chou DTS Lewis S Carrothers AD Queally JM Allison A Barton G Costa ML

Aims

The aim of this study was to assess the feasibility of conducting a full-scale, appropriately powered, randomized controlled trial (RCT) comparing internal fracture fixation and distal femoral replacement (DFR) for distal femoral fractures in older patients.

Patients and Methods

Seven centres recruited patients into the study. Patients were eligible if they were greater than 65 years of age with a distal femoral fracture, and if the surgeon felt that they were suitable for either form of treatment. Outcome measures included the patients’ willingness to participate, clinicians’ willingness to recruit, rates of loss to follow-up, the ability to capture data, estimates of standard deviation to inform the sample size calculation, and the main determinants of cost. The primary clinical outcome measure was the EuroQol five-dimensional index (EQ-5D) at six months following injury.


The Bone & Joint Journal
Vol. 97-B, Issue 2 | Pages 150 - 153
1 Feb 2015
Rogers BA Alolabi B Carrothers AD Kreder HJ Jenkinson RJ

In this study we evaluated whether pre-operative Western Ontario and McMaster Universities (WOMAC) osteoarthritis scores can predict satisfaction following total hip arthroplasty (THA). Prospective data for a cohort of patients undergoing THA from two large academic centres were collected, and pre-operative and one-year post-operative WOMAC scores and a 25-point satisfaction questionnaire were obtained for 446 patients. Satisfaction scores were dichotomised into either improvement or deterioration. Scatter plots and Spearman’s rank correlation coefficient were used to describe the association between pre-operative WOMAC and one-year post-operative WOMAC scores and patient satisfaction. Satisfaction was compared using receiver operating characteristic (ROC) analysis against pre-operative, post-operative and δ WOMAC scores.

We found no relationship between pre-operative WOMAC scores and one-year post-operative WOMAC or satisfaction scores, with Spearman’s rank correlation coefficients of 0.16 and –0.05, respectively. The ROC analysis showed areas under the curve (AUC) of 0.54 (pre-operative WOMAC), 0.67 (post-operative WOMAC) and 0.43 (δ WOMAC), respectively, for an improvement in satisfaction.

We conclude that the pre-operative WOMAC score does not predict the post-operative WOMAC score or patient satisfaction after THA, and that WOMAC scores can therefore not be used to prioritise patient care.

Cite this article: Bone Joint J 2015;97-B:150–3.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVIII | Pages 110 - 110
1 Sep 2012
Carrothers AD Gilbert RE Jaiswal A Richardson JB
Full Access

Purpose

Despite the increasing interest and subsequent published literature on hip resurfacing arthroplasty, little is known about the prevalence of its complications and in particular the less common modes of failure. The aim of this study was to identify the prevalence of failure of hip resurfacing arthroplasty and to analyse the reasons for it.

Method

From a multi-surgeon series (141 surgeons) of 5000 Bimingham hip resurfacings we have analysed the modes, prevalence, gender differences and times to failure of any hip requiring revision surgery.


The Journal of Bone & Joint Surgery British Volume
Vol. 92-B, Issue 10 | Pages 1344 - 1350
1 Oct 2010
Carrothers AD Gilbert RE Jaiswal A Richardson JB

Despite the increasing interest and subsequent published literature on hip resurfacing arthroplasty, little is known about the prevalence of its complications and in particular the less common modes of failure. The aim of this study was to identify the prevalence of failure of hip resurfacing arthroplasty and to analyse the reasons for it.

From a multi-surgeon series (141 surgeons) of 5000 Birmingham hip resurfacings we have analysed the modes, prevalence, gender differences and times to failure of any hip requiring revision. To date 182 hips have been revised (3.6%). The most common cause for revision was a fracture of the neck of the femur (54 hips, prevalence 1.1%), followed by loosening of the acetabular component (32 hips, 0.6%), collapse of the femoral head/avascular necrosis (30 hips, 0.6%), loosening of the femoral component (19 hips, 0.4%), infection (17 hips, 0.3%), pain with aseptic lymphocytic vascular and associated lesions (ALVAL)/metallosis (15 hips, 0.3%), loosening of both components (five hips, 0.1%), dislocation (five hips, 0.1%) and malposition of the acetabular component (three hips, 0.1%). In two cases the cause of failure was unknown.

Comparing men with women, we found the prevalence of revision to be significantly higher in women (women = 5.7%; men = 2.6%, p < 0.001). When analysing the individual modes of failure women had significantly more revisions for loosening of the acetabular component, dislocation, infection and pain/ALVAL/metallosis (p < 0.001, p = 0.004, p = 0.008, p = 0.01 respectively).

The mean time to failure was 2.9 years (0.003 to 11.0) for all causes, with revision for fracture of the neck of the femur occurring earlier than other causes (mean 1.5 years, 0.02 to 11.0). There was a significantly shorter time to failure in men (mean 2.1 years, 0.4 to 8.7) compared with women (mean 3.6 years, 0.003 to 11.0) (p < 0.001).


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 416 - 417
1 Jul 2010
Carrothers AD Jones BS Devaney A Houghton R Jones RS
Full Access

Introduction: As knee arthroplasty is becoming more commonplace in the working population its outcome and probability of return to work is of interest. Despite a wealth of anecdotal evidence about patient return to work post knee arthroplasty there is nothing published in the recent literature. The NHS Direct patient information website quotes patients return to work about 6 to 8 weeks post knee arthroplasty. In order to address this lack of informed information we conducted a retrospective survey.

Methods: 148 consecutive patients of working age, who underwent knee arthroplasty in 2007 were identified by our Electronic Patients Record. (52 male, 96 female, average age 58 years (range 37–65 years)) They were asked to complete a simple questionnaire relating to their occupational history, arthroplasty satisfaction and their current working capacity.

Results: Our survey had a response rate of 67% (99/148 responders, 64 female and 35 male), with a range of follow up from 7 to 19 months. 39% of patients were in employment at the time of their arthroplasty, with 46 % (46/99) returning to some working capacity post surgery. 32% (32/99) patients were able to return to their exact same employment. 88% (28/32) of these patients had worked up to the date of their arthroplasty. There was no correlation between operative indication or type of prosthesis implanted and patients who returned to employment and those who did not.

Conclusion: Despite high expectation in lay literature of ability to work post knee arthroplasty, only 46% of our patients returned to any form of employment. For patients who returned to work, the duration of sick leave prior to their surgery was a strong predictor of whether they returned to any form of employment. Caution must be exercised when informing patients of likelihood of return to work post knee arthroplasty.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 411 - 411
1 Sep 2009
Carrothers AD Gilbert RE Gregory J Oakley MJ
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The St Leger total knee replacement is a bicondylar prosthesis developed as an cheaper alternative to other similar implants of its time. Between October 1993 and June 1999, 144 St Leger total knee replacements were implanted in 114 patients.

The aim of this study was to clinically and radiologically assess these patients after a mean follow up of 10.22 years.

Between February and July 2007 ninety-one patients recalled for clinical evaluation (using functional and objective American Knee Society Scores) and radiological assessment (using the American Knee Society Scoring System). 11 patients had died and 12 were lost to follow up or were medically unfit to attend evaluation. Of the ninety-one patients recalled, 18 had had their prostheses revised (19 knees). 63% of prostheses had survived 10 years or more.

Of the patients with St Leger knees in situ (99 knees) the American Knee Scores showed 78% poor, 10% fair, 6% good and 6% excellent results. Radiological assessment identified 12 arthroplasties that had failed (5 femoral components, 5 tibial components and 4 patellae,) 58 that needed close follow up (18 femoral components, 31 tibial components and 38 patellae) and 29 that were well fixed. A best-case Kaplan-Meier cumulative survivorship was 87% at 10 years. (Worst-case was 71% at 10 years)

These 10 year results showed that the St Leger total knee prosthesis did not perform as well as other bicondylar prostheses of the same generation and had a higher revision rate. Despite favourable published mid-term results, the long-term results for the St Leger total knee replacement have shown it to be unreliable and not worth the initial financial saving.