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Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_2 | Pages 104 - 104
1 Jan 2017
Kan C Chan Y Selvaratnam V Donnachie N
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The femur is a common site for skeletal bony metastases. The aim of this study is to evaluate the outcomes of femoral intramedullary nailing in prophylactic versus therapeutic treatment in femoral metastases.

All femoral nails between April 2011 and November 2015 at a district general hospital were assessed. Intramedullary nailing performed for prophylactic or therapeutic management were included. Outcomes include mortality, survival time and length of stay in hospital.

A total of 40 cases were included. In the prophylactic group there were 25 patients and in the therapeutic group there were 15 patients. In the prophylactic group, mean age was 70 years (range 41–91); male to female ratio is 23:17 and 26 patients of this group was deceased. In the therapeutic group, mean age was 76 years (range 56–92); male to female ratio 15:10 and 10 patients were deceased in this group. The most common primary was prostate carcinoma followed by breast carcinoma. In the prophylactic group, mean survival was 25 weeks (range 2–147) and in the therapeutic group mean survival was 20 weeks (range 2–39). The length of stay was 21 days (range 3–80) in the prophylactic group and 28 days (range 7–63) in the therapeutic group.

Femoral nailing for metastases helps improve quality of life and we observed a mean survival time of 20–25 weeks postoperatively in both therapeutic and prophylactic nailing.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 575 - 575
1 Sep 2012
Selvaratnam V Fountain J Donnachie N Thomas T Carroll F
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INTRODUCTION

Tranexamic Acid (TA) has been shown to decrease peri-operative bleeding in primary Total Knee Replacement (TKR) surgery. There are still concerns with regards to the increased risk of thromboembolic events with the use of TA. The aim of this study was to assess whether the use of pre-operative TA increased the incidence of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE) in TKR.

METHODS

Patients who underwent primary TKR between August 2007 and August 2009 were identified from the databases of three surgeons within the lower limb arthroplasty unit. A retrospective case notes analysis was performed. DVT was diagnosed on Duplex Ultrasound Scan and PE on CT Pulmonary Angiogram. A positive result was a diagnosis of DVT or PE within 3 months of surgery.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 33 - 33
1 Mar 2009
Hakkalamani S Acharya A Finley R Donnachie N
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Introduction: Restoring normal mechanical axis is one of the key goals of the total knee arthroplasty (TKA). The majority of the surgeons resect the tibia perpendicular to its axis in the coronal plane, then use an intra-medullary jig inserted through the centre of the knee or slightly medial to centre of the knee to resect the distal femur at a 6 or 7degree valgus angle. The aim was to establish the safety of using a predetermined valgus angle (VA) and entry point (EP) in the primary TKA. We also studied the relationship between the VA and EP to the height, weight and BMI of the patient.

Materials and Methods: We studied 125 long leg radiographs of 125 patients who underwent TKA under the care of senior author. All the radiographs were taken in the preoperative clinic with knee in full extension and patella facing forward. The radiographs were used to measure the valgus angle and entry point of the femur. The patients with VA between 6–7 degrees and EP at the centre were defined as normal group and rest were defined as outliers.

Results: The VA ranged from 4 to 9.5 degrees (with a mean of 6.8 and SD 1.11). Only 66 (53%) knees had the VA between 6 and 7 degrees. The EP ranged from 30mm medial to 18mm lateral to the centre of the knee with a mean of 7.7mm medial to the centre of the knee (SD 6.1). The EP was at the centre of the knee in 31 (24.8%) knees and lateral to the centre in 19 (15.2%) knees. Only 14 (11.2%) knees were in the normal group. Overall there was no significant relationship between the EP and VA to the height, weight or BMI of the patient at p-value > 0.001.

Conclusions: The resection of distal femur using the predetermined valgus angle, the predetermined entry point is not a safe practice in TKA. The long leg radiographs of the knee should be studied to identify the outliers. In future computer-assisted surgery and digitalisation of the images may obviate the need for this. However, it may be prudent though to use pre-operative templating of long leg radiographs during the learning curve of computer assisted surgery as well.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 46 - 46
1 Mar 2009
Mereddy P Roberts V Hakkalamani S Evans P Donnachie N
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Introduction: The technique of quadriceps sparing knee arthroplasty involves a pure capsular incision, without violation of the extensor mechanism. This capsular incision should be placed distal to Vastus Medialis Obliquus (VMO). The termination of VMO is variable and may make the quadriceps sparing approach difficult. We initiated this study based on the hypothesis that quadriceps sparing approach may not be possible in all the patients undergoing total knee arthroplasty. We examined MRI scans of the knee joint to assess the variation in VMO muscle insertion in relation to the patella and variation of VMO muscle insertion in relation to the age.

Material and Methods: Between Jan 2005 and Dec 2005, 262 MRI scans of the knee joint were performed at our institute. We studied MRI scans of the patients aged 16 years and over. The scans with neoplasm or those without complete set of films were excluded from the study. There were 198 scans available for analysis. Our cohort consisted of 106 female patients and 92 male patients with an average age of 43 years (range 16–86 years). One hundred and thirty four patients were aged less than 50 years and 64 patients were 50 years or older.

We measured patellar height, VMO length on the axial views of the scans. The VMO insertion was calculated from the data and we divided the patients into proximal and distal groups in relation to the VMO termination on the patella. The proximal group included patients with VMO termination proximal to the mid-point of the patella and distal group included patients with VMO termination at or distal to the mid-point of the patella.

Results: The median height of the patella in female patients was 32mm (range 24–44mm) and in male patients was 36mm (range 28–48mm). The VMO length from the apex of the patella was 13.5mm (range 4–28mm) in female patients and 16mm (range 8–32mm) in male patients. Overall there were 119 (60%) patients in the proximal group and 79 (40%) in the distal group. In 20% of patients aged more than 50 years, VMO terminated in the distal half of the patella. In patients less than 50 years old, 50% had the VMO termination in the distal half of patella. A statistically significant inverse relationship was noted between the level of insertion of VMO and the age of the patient (p-value > 0.001, Chi-square test). There was no statistically significant relation between the level of insertion of VMO and the sex of the patient, in either age group (p-value 0.339).

Conclusion: Younger patients are statistically more likely to have a VMO which terminated at or more distal to the mid-point of patella. Therefore, the quadriceps sparing approach may not be possible in these subjects, however it is possible in majority of older patients.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 538 - 538
1 Aug 2008
Roberts V Cunniffe J Donnachie N
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Introduction: Between 1% and 5% of joint prostheses will become infected. The main bacteria involved in prosthetic infections are coagulase negative staphylococci, principally Staphylococcus epidermidis.

The introduction of the laminar flow theatre was responsible for a decrease in wound infection four and a half fold. Further research has found that total body exhaust suits were also responsible for a reduction in infection rate.

These exhaust suits include a toga hood, also supplied sterile and attached to the gown. There is no information from the manufacturers regarding microbial penetration of these hoods. Therefore we have performed an experiment to examine the potential for microbial penetration of these toga hoods, both when wet and dry.

Methods: Confluent lawns of Staphylococcus Epidermidis NCTC 11047 (Fig. 2) were created on two isosensitest agar plates by flood seeding the organism onto the plates, followed by incubation overnight at 37°C.

Both wet and dry toga circles were applied to the previously prepared lawns of Staphylococcus epidermidis NCTC 11047, with the internal surface in contact with the lawn. Swabbings were taken from the external surface of both wet and dry toga circles at regular intervals. The timing of the swabbings were: 1 min, 5 mins, 20 mins, and 60 mins. The swabs were then used to inoculate blood agar plates, which were incubated overnight at 37°C, after which they were examined for growth of Staphylococcus epidermidis.

Discussion: The results are conclusive: there is bacterial transmission from one side of the toga hood to the other. Therefore it is possible to transmit bacteria from the surgeon’s face across the toga material and into the operative field.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 584 - 584
1 Aug 2008
Roberts V Mereddy P Hakkalamani S Donnachie N
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Introduction: The technique of quadriceps sparing knee arthroplasty involves a pure capsular incision, without violation of the extensor mechanism. This capsular incision should be placed distal to Vastus Medialis Obliquus (VMO). It is well known that the termination of VMO is variable and may make the quadriceps sparing approach difficult. We initiated this study based on the hypothesis that the quadriceps sparing approach is not possible in all patients undergoing total knee arthroplasty.

Methods: We examined the axial MRI images of the knee joint performed over a period of 12 months at our institute. A total of 198 MRI scans were analysed between two observers.

To calculate the patellar height the apex of the patella was considered as ‘Reference Slice 1’. The consecutive slices were followed distally to the last slice in which the patella was visible. From ‘Reference Slice 1’ VMO muscle was followed distally to the slice in which the muscle was last visible. We calculated the patella height and VMO muscle length as the product of the number of MRI slices and MRI slice thickness.

Results: Of the 134 patients aged less than 50 years, 68 patients (50.7%) had a VMO that terminated in the proximal half of the patella. Out of 64 patients aged 50 years or older, 51 patients (79.7%) had a VMO that terminated in the proximal half of the patella.

A statistically significant inverse relationship was noted between the level of insertion of VMO and the age of the patient.

Discussion: Our results will have an implication on the use of the quadriceps sparing approach, as they highlight another possible limitation of this approach. Patients need to be warned before the TKA that the quadriceps sparing approach may not be possible in all, especially if they are younger.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 575 - 575
1 Aug 2008
Mereddy P Kumar G George H Hakkalamani S Malik H Donnachie N
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To assess the outcome and implant removal rate following surgical stabilisation of patella fracture.

Sixty-seven patients who underwent surgical stabilisation of patella fracture between January 1999 and December 2004 were retrospectively reviewed to determine the adequacy of fracture stabilisation, fracture union and implant removal rate.

Forty-three were men and 24 were women with a mean age of 49 years (ranged 14–90 years). Table below demonstrates the injury, fracture patterns and fixation methods. There were 3 open fractures and associated injuries were noted in 22 patients. All fractures united even though the fixation was inadequate in 46 patients. Two superficial infections responded to oral antibiotics. One patient had revision surgery at 6 weeks. Twenty-two patients required implant removal between 2 and 20 months (average 11 months) for implant related symptoms. Of the 22 (32.8%) patients requiring implant removal, 16/40 (40%) were less than 60 years and 6/27 (22.2%) were over 60 years. Mean follow up in asymptomatic patients was 8 months (3 to 18 months) and in patients with implant related problems was 17 months (10 to 36 months). Four patients were lost to follow up.

Surgical stabilisation by current techniques demonstrated satisfactory fracture union. However, one in three required second surgery for implant related symptoms. In the under 60 years group, the implant removal rate increased to 40%. Newer techniques to avoid skin irritation need to be considered.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 308 - 308
1 Jul 2008
Loveday D Carroll F Donnachie N
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Introduction: The management of total hip replacement (THR) dislocations is variable after closed reduction. This study was performed to look at the differences in immediate management of THR dislocations after reduction under anaesthesia.

Method: A questionnaire was sent to all members of the British Hip Society asking them about their management of THR dislocations after closed reduction.

Results: 62 orthopaedic consultants completed the questionnaire. A 34% return rate for our postal survey to the 2004 members of the British Hip Society.

For first time dislocations with a stable EUA 8% always used an abduction brace and 50% never used one. 20% were managed with a period of bed rest. For an unstable EUA, 40% always used a brace and 23% never used one. 31% were managed with a period of bed rest. When a brace was used, the majority (75%) used it for 6 weeks (range 2 to 12 weeks).

For recurrent dislocations, with a stable EUA, 65% used a brace for at least 6 weeks. For an unstable EUA 74% used a brace for at least 6 weeks and 15% managed with a brace permanently or until revision.

50% asked the patient to wear the brace 24 hours a day including whilst asleep, the only exception being for washing. The others were varying from 12 to 16 hours a day.

The commonest criteria for revision surgery were recurrent dislocation (seen as more than three), component malposition, aseptic loosening and instability at EUA. The questionnaire was answered by orthopaedic surgeons who all had experience in revision surgery, the majority having performed over 100 revision THR in the past 5 years.

Discussion: The management of dislocated THR is varied between units. There does not appear to be a pattern of management amongst BHS members. The popularity and efficacy of abduction braces remains unknown.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 328 - 328
1 Jul 2008
Hakkalamani S Acharya A Carroll A Finley R Donnachie N
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The aim of this study was to evaluate whether using a predetermined entry point and standard value for valgus cut could restore normal mechanical axis of the TKA.

The study included 125 consecutive patients, who underwent TKA under care of the senior author (NJD). Details of height, weight, BMI were noted. All the radiographs were taken with the patient standing, with the knees in maximum extension, with the patella facing forward. The long leg radiographs were evaluated and the mechanical axis and anatomical axis were marked. The entry point (EP) and the angle between the anatomical and the mechanical axis of the femur ware measured, which is valgus angle of distal femoral cut (VA). Statistical analysis was done using SPSS (Table 1). Proportion of the cases with VA less than 6 degrees or more than 7 degrees were identified. Similarly cases with EP distance less than 0 and more than 5mms were also identified. Cases with VA of 6–7 degrees and EP 0–5mms were identified as one group. Correlation was performed using nonparametric tests.

The results revealed the angle between the anatomical and the mechanical axis ranges from 4 to 9.5 degrees (mean 6.8 degree and standard deviation 1.11 degree). Only 53% had an angle of between 6 and 7 degrees, with 7% of knees having an angle of less than 5 degree or greater than 8 degrees.

The site of entry of the jig showed variation from 30mms medial to the centre to 18mms lateral to the centre with the mean entry point of 5.04mms medial to centre of the notch, with a standard deviation of 8.5mms.

Overall only 33% of the knees templated would have an optimal femoral jig placement and distal femoral angle cut with an entry point in the centre of the notch or up to 5mms medial to centre and a distal valgus cut of between 6 and 7 degrees. The author feel this study gives evidence that if the mechanical axis is to be restored then long leg pre-operative radiographs should be performed and used as a key component to the pre-operative plan.

Table 1. Spearman’s rho correlations, between the valgus angle and entry point to the height, weight and BMI of the patients.