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Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_16 | Pages 32 - 32
17 Nov 2023
Warren J Canden A Farndon M Brockett C
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Abstract

Objectives

The aim of this work was to compare the different techniques and the different fluid permeability of the tissue following each technique through assessing the flow of radiopaque contrast agent using μCT image analysis and 3D modelling.

Methods

Donated human tali specimens (n=12) were prepared through creating a 10mm diameter chondral defect in three different regions of each talus. Each region then underwent one of three surgical techniques: 1) Fine wire drilling, 2) Nanofracture or 3) Microfracture, equidistant sites in each defect to ensure even distribution. Each region then had an addition of 0.1 ml radiopaque contrast agent (Omnipaque™ 300), imaged using a clinical μCT scanner (SCANCO Medical AG, 73.6 μm resolution). Each μCT scan was segmented using Slicer 3D software (The Slicer Community, 2023 3D Slicer (5.2.2)). The segmentation package was used to segment the bone and contrast agent regions in each different surgical site of each sample. Each defect site was created into a cylinder and the ratio of segmented pixels of contrast agent against bone.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_2 | Pages 33 - 33
1 Mar 2021
Koria L Farndon M Lavalette D Jones E Mengoni M Brockett C
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Abstract

Objectives

Over 1% of the global population suffers with ankle osteoarthritis (OA), yet there is limited knowledge on the changes to subchondral bone with OA. In other joints, it has been shown that bone becomes osteosclerotic, with fewer, thicker trabeculae that become hypomineralised, causing an increased apparent bone volume fraction (BV/TV). Microstructural alterations reduce overall joint strength, which may impact the success of late-stage surgical interventions, such as total ankle arthroplasty (TAA). Previous ankle studies have evaluated changes to cartilage, bone plate and bone morphology with OA, hence this study aimed to characterise changes to trabecular architecture.

Methods

Three ankle joints were isolated from non-diseased cadaveric feet (three males: 43, 50 and 57 years, MEEC 18-027). Cylindrical subchondral bone specimens (N=6, 6.5 mm Ø) were extracted from the tibial plafond. Osteoarthritic bone samples (N=6, distal tibia) were sourced from local patients (three males: 65, 58 and 68 years, NREC 07/Q1205/27) undergoing TAA surgery. Specimens were imaged using µCT at a 16 µm isotropic resolution (µCT-100 ScanCo Medical). Virtual cores of bone (6.5 mm Ø) were extracted from the image data of the osteoarthritic specimens and trimmed to a height of 4 mm. BoneJ was used to evaluate key morphological indices: BV/TV; anisotropy (DA); trabecular thickness (Tb.Th); trabecular density (Conn.D) and ellipsoid factor (EF) which characterises rod/plate geometry. Differences between the two groups of specimens were evaluated using a t-test with Bonferroni correction.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 495 - 495
1 Aug 2008
Sturdee SW Harris NJ Farndon M
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Introduction: We report the clinical and radiological results of 137 AES Total Ankle Replacements (TAR)(Biomet, Europe) over a 4-year period.

Methods: 134 patients underwent 137 Total Ankle Replacements. There were 47 females and 87 males. Three patients underwent bilateral procedures. The mean age of the patients was 64 years (48–78). The main indication for surgery was post-traumatic arthritis other indications included primary arthritis, inflammatory arthritis, haemophilia, haemochromatosis, polio, cavo-varus deformity and revision of a loose STAR. The pre-op coronal deformity ranged from 20 degrees varus to 40 degrees valgus. The same surgeon performed all operations. All patients had a clinical and radiological follow-up at 3, 6 and 12 months then annually, thereafter.

Results: At a mean time to follow up of 18 months the mean AOFAS Hindfoot Score was 79. Excluding those patients with other joint disorders the stratified AOFAS score increases to 81. Four patients experienced postoperative talar subsidence and 8 patients had gaps or lysis around the tibial bone implant interface. Three patients developed soft tissue complications, two of which had to have a split skin graft and one of these developed a deep infection. The third patient required a fascio cutaneous local flap. Thirteen patients required a further procedure for postoperative edge loading. No implant has been revised to date. Two patients feel no better off since surgery and one patient feels worse off. The remainder rate their surgery as good or excellent.

Discussion: The early results of the AES TAR are encouraging. Careful management of the soft tissues and correct soft tissue balancing are important. In our series we have modified the surgical technique so less talar bone is resected.

Conclusion: We feel the AES TAR provides encouraging early results.