The purpose of this study was to compare the
diagnostic accuracy for the detection of infection between the culture of
fluid obtained by sonication (SFC) and the culture of peri-implant
tissues (PITC) in patients with early and delayed implant failure,
and those with unsuspected and suspected septic failure. It was
hypothesised that SFC increases the diagnostic accuracy for infection
in delayed, but not early, implant failure, and in unsuspected septic
failure. The diagnostic accuracy for infection of all consecutive
implants (hardware or prostheses) that were removed for failure was
compared between SFC and PITC. This prospective study included 317
patients with a mean age of 62.7 years (9 to 97). The sensitivity
for detection of infection using SFC was higher than using PITC
in an overall comparison (89.9% Sonication is mainly recommended when there is implant failure
with no clear signs of infection and in patients with delayed implant
failure. In early failure, SFC is not superior to PITC for the diagnosis
of infection and, therefore, is not recommended as a routine diagnostic
test in these patients. Cite this article:
Patients with infected arthroplasties are normally
treated with a two-stage exchange procedure using polymethylmethacrylate
bone cement spacers impregnated with antibiotics. However, spacers
may act as a foreign body to which micro-organisms may adhere and
grow. In this study it was hypothesised that subclinical infection may
be diagnosed with sonication of the surface biofilm of the spacer.
The aims were to assess the presence of subclinical infection through
sonication of the spacer at the time of a second-stage procedure,
and to determine the relationship between subclinical infection
and the clinical outcome. Of 55 patients studied, 11 (20%) were
diagnosed with subclinical infection. At a mean follow-up of 12
months (interquartile range 6 to 18), clinical failure was found in
18 (32.7%) patients. Of the patients previously diagnosed with subclinical
infection, 63% (7 of 11) had failed compared with 25% (11 of 44)
of those without subclinical infection (odds ratio 5.25, 95% confidence
interval 1.29 to 21.4, p = 0.021). Sonication of the biofilm of
the surface of the spacer is useful in order to exclude subclinical infection
and therefore contributes to improving the outcome after two-stage
procedures.
For the treatment of the fractures of the proximal extremity of the femur two predominant systems exist: the intramedular nail and the sliding screw plate. The variables at the moment, to be considered, are the weight, age and type of fracture. The principal aims are: To develop models of finite elements of both types of implants and of two types of fracture (stable and unstable), and to integrate the models of finite elements of the implants in the model of fractured femur, to obtain the mechanical behavior of both types of implants and them to fit to the model of finite elements. The analyzed models have been the gamma-3 nail (Stryker, USA) and the PerCutaneus Compression Plate (PCCP), (Gotfried, Israel). The real geometry has been created in the program SolidWorks 11.0 to be treated later in the program of calculation by means of finite elements Ansys. The assembly with nail is more rigid (11.51 mm) that with plate (11.95 mm) on having had a few minor displacements. The tensions that appear in the nail (446 MPa) are major that those of the plate (132.93 MPa), in the unstable fractures. In the unstable fractures, the intramedular nail is more rigid than the system of plate. The tensions to which the nail meets submitted are superior to those of break for what the nail would not be capable of supporting the first cycles of load. It is for it, that the system to using in these cases would be the sliding screw plate.