Aims

The aim of this study was to determine the fracture haematoma (fxH) proteome after multiple trauma using label-free proteomics, comparing two different fracture treatment strategies.

Introduction: Various variants of the extensor indicis (EI) have be described in the literature. We wanted to detect whether there exist any variants of the EI that may cause restricted mobility of the thumb following EI transposition to the extensor pollicis longus (EPL).

Patients & method: Intraoperatively the function of the extensor tendons of 168 hands (98 right / 70 left) of 159 patients (96 female / 63 male) were examined. The function of the muscles was simulated using a tendon-hook. For ethical reasons the approach was not extended for the study.

Results: In 34 of 168 hands 39 accessory tendons were found: 8 were localized between EPL and EI (1 from the EPL to the index; 3 extensor pollicis et indicis; 1 from the EI-muscle to the thumb; 3 to the radial extensor hood of the index). 31 accessory tendon were found ulnar to the EI (2 to the ulnar extensor hood of the index; 25 to the middle finger; 3 to the ring finger; 1 to the little finger). The EI was missing in only one hand, were a strong extensor anularis-tendon was found, which would have been suitable for EPL-reconstruction. 8 of these variants would hinder the thumb from isolated extension following EPL-reconstruction with the EI-tendon.

Conclusion: The extensor tendons should be inspected carefully through EI-transposition for reconstruction of EPL to ensure a free function of the thumb postoperatively. Small accessory tendons that may cause trouble should be cut, strong tendons should be transposed together with the EI-tendon.

PURPOSE: A new device for intraoperative pedography was developed. The purpose of this study was to validate the introduced method with standard dynamic pedography, and to analyze the clinical benefit.

Methods: For an intraoperative introduction of standardized forces to the footsole, a device named Kraftsimulator Intraoperative Pedographie was developed.

The validation was performed in two steps: Step 1. Comparison of standard dynamic pedography (three trials, walking, third step, three trials, mid stance force pattern), static pedography in standing position (three trials) and pedography with KIOP in healthy volunteers (three trials, total force 400 N).. Step 2. Comparison between pedography in standing position, pedography with KIOP in awake and anaesthesized patients (three trials, total force 400 N).

A randomized prospective controlled study comparing treatment with and without intraoperative pedography has started on November 1, 2005. The subjects are randomized into two groups,

a) use of intraoperative pedography, versus

One-year-follow-up including standard dynamic pedography is planned. The following scores are used: American Orthopaedic Foot and Ankle Society (AOFAS), Visual-Analogue-Scale Foot and Ankle (VAS FA), Short-Form 36 (SF36, standardized to 100-point-maximum). Intraoperative consequences after the use of intraoperative pedography were recorded.

Results: Validation Step 1: 30 individuals were included (age, 26.1±8.6 years; gender, male: female = 24: 6). Step 2: 30 individuals were included (age, 55.3±30.3 years; gender, male: female = 24: 6). No significant differences between all measurements of step 1 and 2 were found for step 1 and 2 without the dynamic platform measurements of step 1.

Clinical use: 16 patients were included until January 31, 2006 (ankle correction arthrodesis, n=2; subtalar joint correction arthrodesis, n=4; arthrodesis midfoot, n=4, correction forefoot, 4; Lisfrcan-fracture-dislocation, n=2). 9 patients were randomized for the use of intraoperative pedography. The mean preoperative scores were: AOFAS: 49.6±23.7; VAS FA: 42.2±13.1; SF36: 48.1±23.2. The mean interruption of operative procedure for the intraoperative pedography was 359±34 seconds. In 4/9 cases changes were made after intraoperative pedography during the same operative procedure (correction modified, n=3; screw tightened, n=1). The follow-up has not been completed so far.

Conclusion: Since no statistical significant differences were found between the measurements of intraoperative pedography in anaesthesized individuals and the standard static pedography, the introduced method can be considered to be valid for intraoperative static pedography.

During the clinical use, in 44% of the cases a modification of the surgical correction were made after intraoperative pedography in the same surgical procedure.