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Abstract

Introduction

Cementless fixation of Oxford Unicompartmental Knee Replacements (UKRs) is an alternative to cemented fixation, however, it is unknown whether cementless fixation is as good long-term. This study aimed to compare primary and long-term fixation of cemented and cementless Oxford UKRs using radiostereometric analysis (RSA).

Methodology

Twenty-nine patients were randomised to receive cemented or cementless Oxford UKRs and followed for ten years. Differences in primary fixation and long-term fixation of the tibial components (inferred from 0/3/6-month and 6-month/1-year/2-year/5-year/10-year migration, respectively) were analysed using RSA and radiolucencies were assessed on radiographs. Migration rates were determined by linear regression and clinical outcomes measured using the Oxford Knee Score (OKS).


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_7 | Pages 79 - 79
1 Jul 2022
Fritsch LV Sabah S Xu J Jackson W Merle C Price A Alvand A
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Abstract

Introduction

Re-revision knee replacement (RR-KR) is complex surgery, with a significant impact on individual patients and health resource use. The aim of this study was to investigate early patient-relevant outcomes following RR-KR.

Methodology:

206 patients (250 knees) undergoing RR-KR were recruited from a major revision centre between 2015–2018. Patient-relevant outcomes assessed were: implant survivorship, complications (90-days), joint function and quality of life (final follow-up). Risk factors for further revision surgery at 1 year were investigated using multiple logistic regression.


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_7 | Pages 30 - 30
1 Jul 2022
Middleton R Jackson W Alvand A Bottomley N Price A
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Abstract

Background

Since 2012 we have routinely used the cementless Oxford medial unicompartmental knee arthroplasty (mUKA), with microplasty instrumentation, in patients with anteromedial osteoarthritis (AMOA) meeting modern indications. We report the 10-year survival of 1000 mUKA with minimum 4-year follow-up.

Methods

National Joint Registry (NJR) surgeon reports were interrogated for each senior author to identify the first 1,000 mUKAs performed for osteoarthritis. A minimum of 4 years follow-up was required. There was no loss to follow-up. The NJR status of each knee was established. For each mUKA revision the indication and mechanism of failure was determined using local patient records. The 10-year implant survival was calculated using life-table analysis.


The Bone & Joint Journal
Vol. 100-B, Issue 12 | Pages 1572 - 1578
1 Dec 2018
Middleton R Wilson HA Alvand A Abram SGF Bottomley N Jackson W Price A

Aims

Our unit was identified as a negative outlier in the national patient-reported outcome measures (PROMs) programme, which has significant funding implications. As a centre that carries out a high volume of unicompartmental knee arthroplasty (UKA), our objectives were: 1) to determine whether the PROMs programme included primary UKA when calculating the gain in Oxford Knee Score (OKS); and 2) to determine the impact of excluding primary UKA on calculated OKS gains for primary knee arthroplasty.

Materials and Methods

National PROMs data from England (2012 to 2016) were analyzed. Inclusion of UKA cases in the national PROMs programme was determined using clinical codes. Local OKS gain was calculated for UKA and TKA and compared with the published PROMs results for 2012/13.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_7 | Pages 11 - 11
1 May 2018
Alvand A Grammatopoulos G Quiney F Taylor A Whitwell D Price A Dodd C Jackson W Gibbons M
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Endoprosthetic replacement (EPR) is an available option for the management of massive bone loss around failed knee implants. The aim of this study was to determine the results of knee EPRs performed for non-tumour indications. Since 2007, 85 EPRs were performed for in a single tertiary centre by seven surgeons. Mean age at surgery was 73.5 years (range:35–95) with infection as the most common indication (49%), followed by aseptic loosening (18%), complex primary replacement (16%), fracture (15%) and mechanical failure (2%). Mean follow up was 4 years (range:1–9). Functional outcome was determined using the Oxford Knee Score (OKS). At follow-up, 21 patients were deceased and 2 lost to follow-up. Complication rate was 19%. Of the 7 infected cases, 6 were treated with DAIR (debridement, antibiotics, and implant retention) and one underwent above knee amputation. Four of the patients undergoing DAIR were cleared of infection and 2 are on long-term antibiotics. Accounting for implant revision, loss to follow-up and those on long-term antibiotics as failures, 5-year survival was 89% with an average OKS of 25 (SD=10). This mid-term study shows that distal femur EPR is a valuable option for the increasing burden of complex revision knee surgery


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_8 | Pages 82 - 82
1 Apr 2017
Palmer J Palmer A Jones L Jackson W Glyn-Jones S Price A
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Background

Since 2011, the knee service at the Nuffield Orthopaedic Centre has been offering a neutralising medial opening wedge high tibial osteotomy (HTO) to a group of patients presenting with early medial osteoarthritis of the knee, varus alignment and symptoms for more than 2 years. During development of this practice an association was observed between this phenotype of osteoarthritis and the presence of CAM deformity at the hip.

Methods

A retrospective cohort study. All patients who underwent HTO since 2011 were identified (n=30). Comparator groups were used in order to establish whether meaningful observations were being made: Control group: The spouses of a high-risk osteoarthritis cohort recruited for a different study at our unit (n=20) Pre-arthroplasty group: Patients who have undergone uni-compartmental arthroplasty (UKA) for antero-medial osteoarthritis (n=20)All patients had standing bilateral full-length radiographs available for analysis using in house developed Matlab-based software for hip measurements and MediCAD for lower limb alignment measurements.


Orthopaedic Proceedings
Vol. 98-B, Issue SUPP_23 | Pages 4 - 4
1 Dec 2016
Alvand A Grammatopoulos G de Vos F Scarborough M Athanasou N Kendrick B Price A Gundle R Whitwell D Jackson W Taylor A Gibbons M
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Introduction

The burden of peri-prosthetic joint infection (PJI) following hip and knee surgery is increasing. Endoprosthetic replacement (EPR) is an option for management of massive bone loss resulting from infection around failed lower limb implants.

Aims

To determine clinical outcome of EPRs for treatment of PJI around the hip and knee joint.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 199 - 199
1 Jan 2013
Alvand A Khan T Al-Ali S Jackson W Price A Rees J
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Introduction

Restrictions placed on the working hours of doctors have led to increasing time-pressures on surgical training. Consequently, there has been growing interest in developing new techniques to teach and assess technical skills. The primary aim of this study was to determine whether a novel set of visual parameters assessing visuospatial ability, fine motor dexterity and gaze control could objectively distinguish between varying levels of arthroscopic experience. The secondary aim was to evaluate the correlations between these new parameters and previously established technical skill assessment methods.

Methods

27 subjects were divided into a “novice” group (n=7), “trainee” group (n=15) and expert group (n=5) based on previous arthroscopic experience. All subjects performed a diagnostic knee arthroscopy task on a simulator. Their performance was assessed using new simple visual parameters that included “prevalence of instrument loss,” “triangulation time” and “prevalence of look downs”. In addition, performance was also evaluated using previously validated technical skill assessment methods (a global rating scale and motion analysis).


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 198 - 198
1 Jan 2013
Alvand A Jackson W Khan T Middleton R Gill H Price A Rees J
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Introduction

Motion analysis is a validated method of assessing technical dexterity within surgical skills centers. A more accessible and cost-effective method of skills assessment is to use a global rating scale (GRS). We aimed to perform a validation experiment to compare an arthroscopic GRS against motion analysis for monitoring orthopaedic trainees learning simulated arthroscopic meniscal repairs.

Methods

An arthroscopic meniscal repair task on a knee simulator was set up in a bioskills laboratory. Nineteen orthopaedic trainees with no experience of meniscal repair were recruited and their performance assessed whilst undertaking a standardized meniscal repair on 12 occasions. An arthroscopic GRS, assessing parameters such as “depth perception,” “bimanual dexterity,” “instrument handling,” and “final product analysis” was used to evaluate technical skill. Performance was assessed blindly by watching video recordings of the arthroscopic tasks. Dexterity analysis was performed using a motion analysis tracking system which measured “time taken,” “total path length of the subject's hands,” and “number of hand movements”.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIX | Pages 241 - 241
1 Sep 2012
Khan T Jackson W Beard D Ahmad M Spacie R Jones R Barker K Price A
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Background

Despite interest, the current rate of day-case anterior cruciate ligament reconstruction (ACLR) in the UK remains low. Although specialised care pathways with standard operating procedures (SOPs) have been effective in reducing length of stay following some surgical procedures, this has not been previously reported for ACLR. We evaluate the effectiveness of SOPs for establishing day-case ACLR in a specialist unit.

Methods

Fifty patients undergoing ACLR between May and September 2010 were studied prospectively (“study group”). SOPs were designed for pre-operative assessment, anaesthesia, surgical procedure, mobilisation and discharge. We evaluated length of stay, readmission rates, patient satisfaction and compliance to SOPs. A retrospective analysis of 50 patients who underwent ACLR prior to implementation of the day-case pathway was performed (“standard practice group”).


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 422 - 422
1 Sep 2012
Weston-Simons J Pandit H Kendrick B Beard D Gibbons M Jackson W Gill H Price A Dodd C Murray D
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Introduction

The options for the treatment of the young active patient with unicompartmental symptomatic osteoarthritis and pre-existing Anterior Cruciate Ligament (ACL) deficiency are limited. Patients with ACL deficiency and end-stage medial compartment osteoarthritis are usually young and active. The Oxford Unicompartmental Knee Replacement (UKA) is a well established treatment option in the management of symptomatic end-stage medial compartmental osteoarthritis, but a functionally intact ACL is a pre-requisite for its satisfactory outcome. If absent, high failure rates have been reported, primarily due to tibial loosening. Previously, we have reported results on a consecutive series of 15 such patients in whom the ACL was reconstructed and patients underwent a staged or simultaneous UKA. The aim of the current study is to provide an update on the clinical and radiological outcomes of a large, consecutive cohort of patients with ACL reconstruction and UKA for the treatment of end-stage medial compartment osteoarthritis and to evaluate, particularly, the outcome of those patients under 50.

Methods

This study presents a consecutive series of 52 patients with ACL reconstruction and Oxford UKA performed over the past 10 years (mean follow-up 3.4 years). The mean age was 51 years (range: 36–67). Procedures were either carried out as Simultaneous (n=34) or Staged (n=18). Changes in clinical outcomes were measured using the Oxford Knee Score (OKS), the change in OKS (OKS=Post-op − Pre-op) and the American Knee Society Score (AKSS). Fluoroscopy assisted radiographs were taken at each review to assess for evidence of loosening, radiolucency progression, (if present), and component subsidence.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 92 - 92
1 Jul 2012
Mehmood S Batta V Gulati A Pandit H Bottomley N Gil H Beard D Dodd C Jackson W Murray D Price A
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INTRODUCTION

Establishing a full-thickness cartilage in the lateral compartment and functionally intact ACL is vital before proceeding with unicompartmental knee replacement (UKR). The aim of this study is to assess whether MRI is a useful adjunct in predicting suitability for UKR, as compared to standard and stress radiographs.

METHODS

We identified 50 patients with a knee found suitable for UKR based on their standard and stress radiographs (full-thickness cartilage on lateral side). These patients underwent an additional cartilage-specific MRI scan to identify the status of ACL and the lateral compartment. The final decision regarding the suitability for UKR was based on the intra-operative observation.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 43 - 43
1 Jul 2012
Price A Jackson W Field R Judge A Carr A Arden N Murray D Dawson J Beard D
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Purpose

The Oxford Knee Score (OKS) is a validated and widely used PROM that has been successfully used in assessing the outcome of knee arthroplasty (KA). It has been adopted as the nationally agreed outcome measure for this procedure and is now routinely collected. Increasingly, it is being used on an individual patient basis as a pre-operative measure of osteoarthritis and the need for joint replacement, despite not being validated for this use. The aim of this paper is to present evidence that challenges this new role for the OKS.

Method

We have analysed pre-operative and post-operative OKS data from 3 large cohorts all undergoing KA, totalling over 3000 patients. In addition we have correlated the OKS to patient satisfaction scores. We have validated our findings using data published from the UK NJR.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 74 - 74
1 Jul 2012
Al-Ali S Alvand A Gill HS Beard DJ Jackson W Price AJ Rees JL
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Rheumatology and Musculoskeletal Sciences, NIHR Biomedical Research Unit, University of Oxford and the Nuffield Orthopaedic Hospital, Oxford

Purpose

The aim of this study was to use motion analysis to objectively study the learning curve of surgical trainees performing arthroscopic meniscal repair on a training model in a skills laboratory.

Background

With improving technology and an appreciation of its likely chondroprotective effects, meniscal repair surgery is becoming more common. It remains a difficult procedure and is not routinely learnt during surgical training.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 64 - 64
1 Jul 2012
Al-Ali S Khan T Jackson W Beard D Price A
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Purpose

The purpose was to determine if the use of cold irrigation fluid in routine knee arthroscopy leads to a reduction in post operative pain.

Background

Some surgeons use cooled irrigation fluid in knee arthroscopy in the hope that it may lead to a reduction in post operative pain and swelling. There is currently no evidence for this, although there is some evidence to support the use of cold therapy post operatively in knee surgery.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 70 - 70
1 Jul 2012
Erturan G Neely J Richards N Price A Jackson W Khan T
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A feasibility study of the use of an MRI based patient specific knee arthroplasty system within the NHS.

Introducing new technologies within a public funded health system can be challenging. We assess the use and potential benefit of customised jigs for knee arthroplasty. Outcomes assessed were safety and accuracy of implantation.

Eight knee replacements using custom jigs were compared to 11 conventionally instrumented replacements matched to surgeon and operative day. Parameters measured include tourniquet time; drain output; hospital stay; adjusted change in haemoglobin; complications; and component position on post-operative long-leg alignment films

None of the parameters observed demonstrated a statistically significant difference from the conventional arthroplasty group. No complications were seen in either group. No significant differences were seen in alignment.

Our early experiences show that this technology appears safe and allows accurate implantation of the prosthesis. There was a trend for decreased stay and blood loss. The health economic benefits of navigational arthroplasty have been demonstrated in other studies and come from the lack of instrumentation of the intramedullary canal. MRI based patient specific instrumentation is considered technically easier and more convenient than intra-operative navigation. A larger study is planned to assess the health economic implications of adopting this new technology.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 416 - 416
1 Jul 2010
Bottomley N McNally E Ostlere S Beard D Gill H Kendrick B Jackson W Gulati A Simpson D Murray D Dodd C Price A
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Introduction: This study explores whether modern magnetic resonance imaging (MRI) with improved cartilage sequencing is able to show a more detailed view of anteromedial osteoarthritis of the knee (AMOA). Preoperative assessment of patients and selection of intervention is very important and preoperative imaging forms an integral part of this. Modern MRI technology may allow us to visualize in great detail the structures and cartilage within the knee, providing a better understanding of the pathoanatomy of AMOA. This will be useful in preoperative assessment and surgical management of patients.

Methods: 50 patients with a radiographic diagnosis of anteromedial osteoarthritis of the knee and had been listed for unicompartmental knee arthroplasty (UKA) had MRI as part of their pre-op workup. At operation all were deemed suitable for UKA using the current Oxford indications. The image sequences were coronal, axial and sagittal with a predetermined cartilage protocol. The state of the ACL, cartilage wear location and pattern, presence of osteophytes and subchondral high signal were assessed.

Results: All the ACLs were visualized and in continuity, however 40% showed intrasubstance high signal.

100% of medial compartments showed full thickness anteromedial loss with preservation of the posteromedial cartilage. When present, the meniscus was extruded in 96% of cases.

90% of lateral compartments were normal and none had full thickness cartilage loss. However 10% showed high signal in the tibial plateau.

There was a highly reproducible pattern of osteophyte formation; 94% posteromedial and posterolateral aspect of medial femoral condyle; 90% medial tibial; 80% medial femoral and 84% lateral intercondylar notch.

Discussion: This study maps the pattern of anteromedial osteoarthritis using modern MRI techniques. This has importance in determining preoperative indications (preservation of ACL and posteromedial cartilage); surgical technique (determine pattern of osteophytes requiring resection) and potentially important for long-term outcome (early lateral compartment changes).


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 69 - 69
1 Mar 2010
Hinsley D Jackson W Theologis T Giele H Gibbons C
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Introduction: Young active patients with malignant tumours arising in the distal fibula, requiring bone and soft tissue excision, present a challenge to the treating surgeon. Wide local excision is advocated, to achieve clearance, however, disruption of the ankle mortise results and fusion is often required to restore stability. The loss of movement is poorly tolerated in the younger patient and leads to progressive degenerative changes in surrounding joints.

Method: Excision of the distal fibula lesion followed by rotation of the proximal fibula on its vascular pedicle recreates the ankle mortise with consequent restoration of ankle stability and retaining ankle movement.

Results: Between 2000 and 2008, we have performed this technique on four patients, (2F, 2M) mean age 21 (13–33). Diagnoses were that of chondrosarcoma, parosteal osteosarcoma, Ewings sarcoma and osteofibrodysplasia. Follow up at 5 years (18m-8 year) with no evidence of local or distant recurrence. One case was complicated by deep infection requiring surgical debridement and antibiotic therapy. In all cases the fibula grafts survived. Good to excellent functional results were achieved (Toronto Extremity Salvage Scores, mean 88 range 82–94).

Discussion: We will present the technical aspects of this procedure with particular reference to the most recent case, performed on a young female patient with parosteal osteosarcoma.

We believe this technique provides good oncological and functional results and recommend this treatment option is considered in young active patients required distal fibula excisions for sarcoma.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_III | Pages 418 - 418
1 Sep 2009
Jackson W van der Tempel W Salmon L Williams H Pinczewski L
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This study evaluated the long term outcome of isolated posterior cruciate ligament (PCL) reconstruction. Thirty patients underwent surgery with hamstring tendon autograft after failing conservative management. At 10 years after surgery patients were assessed with radiographs, full IKDC examination and KT1000 instrumented testing. The mean IKDC subjective knee score was 87 out of a possible 100. Regular participation in moderate to strenuous activities improved from 26% preoperatively to 88% of patients. At 10 years endoscopic reconstruction of the PCL with hamstring tendon autograft is effective in reducing knee symptoms. Patients can expect to continue participating in moderate to strenuous activties over the long term. Osteoarthritis is observed in some patients with 18% showing some loss of joint space which compares favorably with non-operatively managed PCL injuries. This is a successful procedure for symptomatic patients with PCL laxity who have failed conservative management.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_II | Pages 365 - 365
1 May 2009
Tryfonidis M Jackson W Mansour R Ostlere S Teh J Cooke PH Sharp RJ
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Introduction: Acquired pes planus is caused by mechanical uncoupling of the bones of the tarsus due to failure of the osseoligamentous complex that maintains the medial longitudinal arch of the foot. The most common cause of acquired flat foot deformity in adults is posterior tibialis tendon dysfunction. A solitary previous case report has documented an alternative aetiology of acquired flat foot in adults due to isolated spring ligament rupture; in that case diagnosis was made intra-operatively.

Materials and Methods: We present 9 cases of acquired flat foot deformity that were caused by isolated spring ligament insufficiency, mainly presenting after an eversion injury of the ankle. We present the clinical sign of ability to single leg tiptoe, but with persistent forefoot abduction and heel valgus, that allows differentiation of this diagnosis from posterior tibialis tendon dysfunction. In addition we illustrate the radiological features of this condition which have not been previously described and allow confirmation of the diagnosis non-operatively.

Results: Six patients have been managed with orthotics and three underwent surgery; one patient who presented early had an isolated repair of the spring ligament complex and has done well. The remaining two patients required a calcaneal osteotomy and Flexor Digitorum Longus transfer as for a PTT reconstruction. In all these three patients the spring ligament was found to be completely ruptured during surgery.

Discussion: This type of injury may not be as rare as previously thought and demonstrates the importance of the spring ligament on its own in maintaining the medial longitudinal arch. Awareness of this condition could lead to earlier diagnosis and better prognosis with earlier treatment.

Conclusion: We propose that early diagnosis (with ultrasound confirmation) and management of this condition would offer a better prognosis and allow less interventional surgery.