Altered distal radioulnar joint contact (DRUJ) mechanics are thought to cause degenerative changes in the joint following injury. Much of the current research examining DRUJ arthrokinematics focuses on the effect of joint malalignment and resultant degenerative changes. Little is known regarding native cartilage contact mechanics in the distal radioulnar joint. Moreover, current techniques used to measure joint contact rely on invasive procedures and are limited to statically loaded positions. The purpose of this study was to examine native distal radioulnar joint contact mechanics during simulated active and passive forearm rotation using a non-invasive imaging approach. Testing was performed using 8 fresh frozen cadaveric specimens (6 men: 2 women, mean age 62 years) with no CT evidence of osteoarthritis. The specimens were thawed and surgically prepared for biomechanical testing by isolating the tendons of relevant muscles involved in forearm rotation. The humerus was then rigidly secured to a wrist simulator allowing for simulated active and passive forearm rotation. Three-dimensional (3D) cartilage surface reconstructions of the distal radius and ulna were created using volumetric data acquired from computed tomography after joint disarticulation. Using optically tracked motion data and 3D surface reconstructions, the relative position of the cartilage models was rendered and used to measure DRUJ cartilage contact mechanics. The results of this study indicate that contact area was maximal in the DRUJ at 10 degrees of supination (p=0.002). There was more contact area in supination than pronation for both active (p=0.005) and passive (p=0.027) forearm rotation. There was no statistically significant difference in the size of the DRUJ contact patch when comparing analogous rotation angles for simulated active and passive forearm motion (p=0.55). The contact centroid moved 10.5±2.6 mm volar along the volar-dorsal axis during simulated active supination. Along the proximal-distal axis, the contact centroid moved 5.7±2.4 mm proximal during simulated active supination. Using the technique employed in this study, it was possible to non-invasively examine joint cartilage contact mechanics of the distal radioulnar joint while undergoing simulated, continuous active and passive forearm rotation. Overall, there were higher contact area values in supination compared with pronation, with a peak at 10 degrees of supination. The contact centroid moved volarly and proximally with supination. There was no difference in the measured cartilage contact area when comparing active and passive forearm rotation. This study gives new insight into the changes in contact patterns at the native distal radioulnar joint during simulated forearm rotation, and has implications for increasing our understanding of altered joint contact mechanics in the setting of deformity.
Distal radius fractures are the most common fracture of the upper extremity. Malunion of the distal radius is a common clinical problem after these injuries and frequently leads to pain, stiffness loss of strength and functional impairments. Currently, there is no consensus as to whether not the mal-aligned distal radius has an effect on carpal kinematics of the wrist. The purpose of this study was to examine the effect of dorsal angulation (DA) of the distal radius on midcarpal and radiocarpal joint kinematics, and their contributions to total wrist motion. A passive wrist motion simulator was used to test six fresh-frozen cadaveric upper extremities (age: 67 ± 17yrs). The specimens were amputated at mid humerus, leaving all wrist flexor and extensor tendons and ligamentous structures intact. Tone loads were applied to the wrist flexor and extensor tendons by pneumatic actuators via stainless steel cables. A previously developed distal radius implant was used to simulate native alignment and three DA deformity scenarios (DA 10 deg, 20 deg, and 30 deg). Specimens were rigidly mounted into the simulator with the elbow at 90 degrees of flexion, and guided through a full range of flexion and extension passive motion trials (∼5deg/sec). Carpal motion was captured using optical tracking; radiolunate and capitolunate joint motion was measured and evaluated. For the normally aligned radius, radiolunate joint motion predominated in flexion, contributing on average 65.4% (±3.4). While the capitolunate joint motion predominated in extension, contributing on 63.8% (±14.0). Increasing DA resulted in significant alterations in radiolunate and capitolunate joint kinematics (p<0.001). There was a reduction of contribution from the capitolunate joint to total wrist motion throughout flexion-extension, significant from 5 degrees of wrist extension to full extension (p = 0.024). Conversely, the radiolunate joint increased its contribution to motion with increasing DA; significant from 5 degrees of wrist extension to full extension as the radiolunate and capitolunate joint kinematics mirrored each other. A DA of 30 degrees resulted in an average radiolunate contribution of 72.6% ± 7.7, across the range of motion of 40 degrees of flexion to 25 degrees of extension. The results of our study for the radius in a normal anatomic alignment are consistent with prior investigators, showing the radiocarpal joint dominated flexion, and the midcarpal joint dominated extension; with an average 60/40 division in contributions for the radiocarpal in flexion and the midcarpal in extension, respectfully. As DA increased, the radiocarpal joint provided a larger contribution of motion throughout flexion and extension. This alteration in carpal kinematics with increased distal radius dorsal angulation may increase localised stresses and perhaps lead to accelerated joint wear and wrist pain in patients with malunited distal radial fractures.
Wrist motion is achieved primarily via rotation at the radiocarpal and midcarpal joints. The contribution of each carpal bone to total range of motion has been previously investigated, although there is no consensus regarding the influence of each structure to global wrist motion. The objective of this comprehensive in-vitro biomechanical study was to determine the kinematics of the capitate, scaphoid and lunate during unconstrained simulated wrist flexion-extension. In addition, this study examined the effect of motion direction (i.e. flexion or extension) on the kinematics and contribution of the carpal bones. Seven fresh frozen cadaveric upper limb specimens (age: 67±18 yrs) were amputated mid-humerus, and the wrist flexors/extensors were exposed and sutured at their musculotendinous junctions. Each specimen was mounted on a wrist motion simulator in neutral forearm rotation with the elbow at 90° flexion. Passive flexion and extension motion of the wrist was simulated by moving a K-wire, inserted into the third metacarpal, through the flexion/extension motion arc at a speed of ∼5 mm/sec under muscle tone loads of 10N. Carpal kinematics were captured using optical tracking of bone fixated markers. Kinematic data was analysed from ±35° flexion/extension. Scaphoid and lunate motion differed between wrist flexion and extension, but correlated linearly (R‸2=0.99,0.97) with capitate motion. In wrist extension, the scaphoid (p=0.03) and lunate (p=0.01) extended 83±19% & 37±18% respectively relative to the capitate. In wrist flexion, the scaphoid (p=1.0) and lunate (p=0.01) flexed 95±20% and 70±12% respectively relative to the capitate. The ratio of carpal rotation to global wrist rotation decreased as the wrist moved from flexion to extension. The lunate rotates on average 46±25% less than the capitate and 35±31% less than the scaphoid during global wrist motion (p=0.01). The scaphoid rotates on average 11±19% less than the capitate during wrist flexion and extension (p=0.07). There was no difference in the contribution of carpal bone motion to global wrist motion during flexion (p=0.26) or extension (p=0.78). The capitate, lunate and scaphoid move synergistically throughout planar motions of the wrist. Our study found that both the scaphoid and lunate contributed at a greater degree during wrist flexion compared to extension, suggesting that the radiocarpal joint plays a more critical role in wrist flexion. Our results agree with previous studies demonstrating that the scaphoid and lunate do not contribute equally to wrist motion and do not function as a single unit during planar wrist motion. The large magnitude of differential rotation observed between the scaphoid and lunate may be responsible for the high incidence of scapholunate ligament injuries relative to other intercarpal ligaments. An understanding of normal carpal kinematics may assist in developing more durable wrist arthroplasty designs.
Long term outcomes of distal radius fractures have rarely been studied prospectively and do not traditionally extend past 1–2 years following treatment. The purpose of this study was to describe the long term patient-rated pain and disability of patients after a distal radius fracture and to also determine the differences in patient reported pain and disability after one year following injury and at the long term follow-up. Patients who had previously participated in a prospective study, where baseline and standardised one year follow-up were performed following a distal radius fracture were contact to participate in this long term follow-up (LTFU) study. Eligible cases that consented agreed to evaluation which included being sent a package in the mail contain a letter of information and questionnaire. Baseline demographic data including age and sex, as well as date of fracture, mechanism of fall and attending physician information was obtained for all participating subjects. Patient rated pain and disability was measured at baseline, one year and at long-term follow-up using the Patient Rated Wrist Evaluation (PRWE). Patients were categorised as having had a worse outcome (compared to one year follow-up PRWE scores) if their LTFU PRWE score increased by 5 points, having no change in status (if their score changed by four or less points) or improved if their LTFU PRWE score decreased by 5 or more points. Sixty-five patients (17 male, 48 female) with an average age of 57 years at the time of injury and 67 years at follow-up were included in the study. The mean length of follow-up was 10.7 (± 5.8) years (range: 3–19 years). Overall, 85% of patients reported having no change or had less patient-reported pain and disability (PRWE) at their long-term follow-up compared to their one year PRWE scores. As well, one year PRWE scores were found to be predictive (20.2%) of the variability in long term PRWE score (p=0.001). This study provided data on a cohort of prospectively followed patients with a distal radius fracture, approximately 10 years after injury. This data may be useful to clinicians and therapists who are interested in determining the long term effects of this frequently occurring upper extremity fracture. The results of this study indicate that after 10 years following a distal radius fracture, 85% of patients will have good outcomes. The results of this study also indicate that majority of cases, if patients have a low amount of pain and disability at one year, then these outcomes will also be true approximately 10 years later.
Wrist motion is achieved primarily via rotation at the radiocarpal and midcarpal joints. The contribution of each carpal bone to total range of motion has been previously investigated, although there is no consensus regarding the influence of each structure to global wrist motion. The objective of this comprehensive in-vitro biomechanical study was to determine the kinematics of the capitate, scaphoid and lunate during unconstrained simulated wrist flexion-extension. In addition, this study examined the effect of motion direction (i.e. flexion or extension) on the kinematics and contribution of the carpal bones. Seven fresh frozen cadaveric upper limb specimens (age: 67±18 yrs) were amputated mid-humerus, and the wrist flexors/extensors were exposed and sutured at their musculotendinous junctions. Each specimen was mounted on a wrist motion simulator in neutral forearm rotation with the elbow at 90° flexion. Passive flexion and extension motion of the wrist was simulated by moving a K-wire, inserted into the third metacarpal, through the flexion/extension motion arc at a speed of ∼5 mm/sec under muscle tone loads of 10N. Carpal kinematics were captured using optical tracking of bone fixated markers. Kinematic data was analysed from ±35° flexion/extension. Scaphoid and lunate motion differed between wrist flexion and extension, but correlated linearly (R^2=0.99,0.97) with capitate motion. In wrist extension, the scaphoid (p=0.03) and lunate (p=0.01) extended 83±19% & 37±18% respectively relative to the capitate. In wrist flexion, the scaphoid (p=1.0) and lunate (p=0.01) flexed 95±20% and 70±12% respectively relative to the capitate. The ratio of carpal rotation to global wrist rotation decreased as the wrist moved from flexion to extension. The lunate rotates on average 46±25% less than the capitate and 35±31% less than the scaphoid during global wrist motion (p=0.01). The scaphoid rotates on average 11±19% less than the capitate during wrist flexion and extension (p=0.07). There was no difference in the contribution of carpal bone motion to global wrist motion during flexion (p=0.26) or extension (p=0.78). The capitate, lunate and scaphoid move synergistically throughout planar motions of the wrist. Our study found that both the scaphoid and lunate contributed at a greater degree during wrist flexion compared to extension, suggesting that the radiocarpal joint plays a more critical role in wrist flexion. Our results agree with previous studies demonstrating that the scaphoid and lunate do not contribute equally to wrist motion and do not function as a single unit during planar wrist motion. The large magnitude of differential rotation observed between the scaphoid and lunate may be responsible for the high incidence of scapholunate ligament injuries relative to other intercarpal ligaments. An understanding of normal carpal kinematics may assist in developing more durable wrist arthroplasty designs.
Fracture or resection of the radial head can cause unbalance and long-term functional complications in the elbow. Studies have shown that a radial head excision can change elbow kinematics and decrease elbow stability. The radial head is also important in both valgus and varus laxity and displacement. However, the effect of radial head on ulnohumeral joint load is not known. The objective of this experimental study was to compare the axial loading produced at the ulnohumeral joint during active flexion with and without a radial head resection. Ten cadaveric arms were used. Each specimen was prepared and secured in an elbow motion simulator. To simulate active flexion, the tendons of the biceps, brachialis, brachioradialis, and triceps were attached to servo motors. The elbow was moved through a full range of flexion. To quantify loads at the ulnohumeral joint, a load cell was implanted in the proximal ulna. Testing was conducted in the intact then radial head resected case, in supination in the horizontal, vertical, varus and valgus positions. When comparing the average loads during flexion, the axial ulnar load in the horizontal position was 89±29N in an intact state compared to 122±46N during radial head resection. In the vertical position, the intact state produced a 67±16N load while the resected state was 78±23N. In the varus and valgus positions, intact state resulted in loads of 57±26N and 18±3N, respectively. Conversely, with a radial head resection, varus and valus positions measured 56±23N and 54±23N loads, respectively. For both joint configurations, statistical differences were observed for all flexion angles in all arm positions during active flexion (p=0.0001). When comparing arm positions and flexion angle, statistical differences were measured between valgus, horizontal and vertical (p<0.005) except for varus position (p=0.64). Active flexion caused a variation in loads throughout flexion when comparing intact versus radial head resection. The most significant variation in ulnar loading occurred during valgus and horizontal flexion. The vertical and varus position showed little variation because the position of the arm is not affected by the loss of the radial head. However, in valgus position, the resected radial head creates a void in the joint space and, with gravity, causes greater compensatory ulnar loading. In the horizontal position, the forearm is not directly affected by gravitational pull and cannot adjust to counterbalance the resected radial head, therefore loads are localised in the ulnohumeral joint. These findings prove the importance of the radial head and that a radial head resection can overload the ulnohumeral side.
This study examined the effect of wrist fracture deformities on the work and kinematics of forearm rotation in vitro. An osteotomy was performed on eight fresh frozen upper extremities just proximal to the distal radioulnar joint and a three-degree of freedom modular implant designed to simulate distal radius fracture deformities was secured in place. This allowed for accurate adjustment of dorsal angulation, dorsal displacement, and radial shortening. The study was divided into two parts, the first phase examining the effects of distal radius deformity and the second sectioned the TFCC and repeated the testing, reviewing the effects of a progressive soft tissue injury in conjunction with distal radius deformity. The magnitude of muscle activity required to achieve the motion, namely the work of rotation, was affected by the degree of simulated malunion and whether the TFCC was intact or sectioned. Increasing dorsal angulation caused a significant reduction in forearm pronation and supination. Once the TFCC ligaments were sectioned, the range of motion was restored to the pre-injured state for both pronation and supination. Dorsal displacement decreased the forearm range of motion significant at 10mm from native (p=0.02) and 5mm (p=0.03) for intact pronation. Radial shortening of 5mm or less had no effect on forearm rotation. However, 7.5mm of radial shortening could not be achieved in any of the specimens until the TFCC was divided. Our results reveal that a significant loss of forearm rotation can be expected if a radius fracture exceeds thirty degrees dorsal angulation or 10mm of dorsal displacement. Radial shortening greater than 7.5mm could only be achieved concomitant with a TFCC rupture. This and further study in this area, should assist clinicians in developing treatment strategies for their patients with fractures and deformities of the distal radius.
We compared the initial strength of two techniques for repair of rotator cuff tears. Eight paired cadaveric shoulders with a standardized supraspinatus defect were studied. A transosseous suture and anchor repair was conducted on each side. Specimens were tested under cyclic loading, while fixation was monitored with an optical tracking technique. Mode of failure, number of cycles and load to failure were measured for 50% (5 mm) and 100% (10 mm) loss of repair. Anchors provide improved repair strength at 50% repair loss, in comparison to sutures (p<
0.05). Strength was unaffected by bone mineral density, age and gender. The purpose of this study was to compare the initial strength of two rotator cuff repair techniques. Repair strength with anchors was superior to sutures. Strength was unaffected by bone quality. Anchors, enabling a quicker, less invasive arthroscopic repair, offer improved fixation over sutures, which are more time consuming and invasive. Eight paired shoulders with a standardized supra-spinatus defect were randomized to anchor or suture repair, and subjected to cyclic loading. Repair migration was measured using a digital camera. Failure mode, cycles and load were measured for 50% and 100% loss of repair. Results were correlated with bone mineral density, age and gender. The anchors failed at the anchor-tendon interface, whereas the sutures failed through the sutures. Mean values for 50% loss of repair were 205.6 ± 87.5 cycles and 43.8 ± 14.8 N for the sutures, and 1192.5 ± 251.7 cycles and 156.3 ± 19.9 N for the anchors (p<
0.05). The corresponding values for 100% loss of repair were 2457.5 ± 378.6 cycles and 293.8 ± 27.4 N for the sutures, and 2291.9 ± 332.9 cycles and 262.5 ± 28.0 N for the anchors (p>
0.05). These results did not correlate with bone quality. This study has demonstrated that anchors provide improved repair strength, in comparison to sutures. This may be due to the relative less deformability of the anchors. Repair strength did not correlate with bone quality. This may be attributed to each repair failing primarily through the repair construct or at the anchor-tendon interface, and not through bone.
This cohort study reports outcomes of patients with comminuted radial head fractures treated with a modular radial head arthroplasty. Twenty-six patients (mean age = fifty-four) were prospectively followed at three, six, twelve, and twenty-four months following surgery. Patient satisfaction with this procedure was high. This data indicates favorable results using a modular radial head arthroplasty with rapid improvement in disability and physical impairment occurring in all measures in the first six months and further improvement in most patients up to two years. The Mayo Elbow Performance Index was at one year and eighty-four at two years. To investigate the objective and subjective outcomes of unreconstructable radial head fractures treated with a modular radial head arthroplasty. This data indicates favorable results using a modular radial head arthroplasty with improvement in satisfaction, disability and physical impairment occurring in all measures in the first six-months and continued improvement for up to two-years. Comminuted radial head fractures are challenging to treat with ORIF. Radial head arthroplasty is an alternative treatment that compares favorably to reported results for ORIF of similar fractures. Significant improvements were noted over time in self-reported and measured impairments as follows: ASES pain: baseline = 30/50, two years = 15/50; ASES function: baseline = 5/36, two years 27/36; MEPI one year = eighty-two, two years = eight-four. At two years, little impairment was observed compared to the unaffected side in grip 22/26 kg, flexion 141°/145°, or pronation 74°/79°. Moderate differences were noted in extension 28°/2°, supination 57°/72° and strength measures: extension = 29/38, flexion = 31/40, supination = 43/65, pronation = 37/53 (Nm). Patient satisfaction was high at three months (9/10) and remained high at two years (9.1/10). A cohort of twenty-six patients (seventeen female, mean age fifty-four) with non-reconstructable radial head fractures was treated using a modular metallic radial head arthroplasty (Evolve TM, Wright Medical Technology, Arlington, TN). All patients were prospectively followed at three, six, twelve and twenty-four months. Self-report of limb function, general health, measured ROM and isometric strength were assessed by an independent observer. Funding Institution research foundation support was provided by Wright Medical Technology. None of the authors received direct compensation for commercial products related to the content of this study.
The functional outcomes of twenty-eight patients with capitellum and trochlea fractures treated with open reduction and internal fixation were evaluated at a mean follow-up of fifty-five ± thirty-three months. Patients were independently evaluated by a series of questionnaires, radiographs, physical examination and strength testing. Patients with simple fractures did better than those with complicated fractures. The average DASH score was 19/100 and the average ROM was 20 – 130°. Two fractures did not unite and required conversion to total elbow arthroplasty. A classification system is proposed based on fracture patterns, surgical technique and clinical outcomes. Capitellum and trochlea fractures are uncommon fractures of the distal humerus. There is limited information about the functional outcome of patients managed with open reduction and internal fixation. The functional outcome of twenty-eight patients (average age: forty-three ± thirteen years [range, twenty – seventy-one]) who were treated with open reduction and internal fixation for capitellum and trochlea fractures was evaluated at a mean follow-up of fifty-five ± thirty-three months (range, fourteen – one hundred and twenty-one). Patient outcomes were assessed by physical examination, radiographs, range of motion measurements, strength testing and self reported questionnaires (DASH, SF-36 ASES and PREE elbow scales). There were eleven fractures involving the capitellum, four involving the capitellum and trochlea as one piece and thirteen in which the capitellum and trochlea were separate fragments. These fractures were further defined by the presence or absence of posterior comminution. Fourteen had isolated fractures and fourteen were associated with other elbow, forearm or wrist injuries. Patients with complicated fractures required more extensive surgery, had more complications resulting in secondary procedures and had poorer outcomes compared to those with simple fractures. The average DASH score (19/100), quality of life scores (SF-36: Physical=46, Mental=49) and the average ROM (20 – 130°) suggest favorable patient outcomes overall. Patients with simple fractures had better results than those with more complicated fractures. A fracture classification system based on fracture patterns, surgical technique and clinical outcomes is proposed.
To determine the relationship between forearm muscle activity and joint reaction force (JRF) in the distal radioulnar joint (DRUJ). The DRUJ reaction force is linearly related to the muscle activity of the PT and biceps, but not necessarily to the activity of the supinator and PQ. This work has implications for biomechanical modelling, implant design, fixation and rehabilitation protocols following DRUJ arthroplasty. JRFs were found to increase linearly with muscle load for all muscles simulated (biceps, pronator teres (PT), pronator quadratus (PQ), supinator) in all forearm positions tested (supination, neutral and pronation) (correlation coefficient r>
0.85, p<
0.01) with two exceptions; simulation of the PQ in the neutral position (r=−0.65, p=0.2), and the supinator in the pronated position (r=0.72, p=0.2). Biceps simulation generated larger JRF magnitudes in all positions compared to other muscles (p<
0.001), and the PQ generated larger JRF magnitudes compared to the supinator (p=0.05). Ulnar head arthroplasty was performed with a replacement ulnar head implant instrumented with strain gauges to allow measurement of the DRUJ reaction force. An upper extremity joint simulator applied muscle loads in seven fresh frozen cadaveric upper extremities through computer-controlled pneumatic actuators. Load was varied in 10N increments from 10-80N (biceps and PT) and from 10-50N (PQ and supinator). A hand clamp was used to restrain the forearm in varying positions. The results illustrate that broad insertion and non-linear muscles may not be linearly correlated to joint reaction force in the DRUJ. Please contact author for diagrams and graphs.
Quantitative measurements of load transfer through the distal radioulnar joint (DRUJ) are limited. An instrumented ulnar head prosthesis was developed to measure bending and torsion moments about the three anatomic axes of the ulna. This device has shown repeatable loading data following insertion in a cadaveric specimen during active forearm rotation trials conducted in an To develop a system to quantify A load-measuring system was developed that was easily surgically inserted, and produced repeatable loading data. The instrumented implant developed in this study will contribute to the optimization of surgical procedures and implant design parameters related to distal ulnar arthroplasty. Four pairs of strain gauges were applied to the stem of an ulnar head prosthesis to measure bending and torsion moments about the three anatomic axes of the ulna. Three ulnar heads were machined with varying eccentricities (axisymmetric, 1.5 mm offset and 3.0 mm offset). The implant was inserted in one unpreserved cadaveric upper extremity and active forearm rotation induced using a computer controlled joint simulator. Repeatability (assessed using the maximum standard deviation over 5 trials of pronation and supination) was less than 9% of the output range for all loads. Bending and torsion moments between −0.4 and 0.5 Nm, correlating to joint loads between 0 and 50 N, were measured. The measured loads followed a consistent pattern with forearm position. Higher loads were noted for the eccentric implant heads compared to the axisymmetric head, especially at the extreme ranges of rotation. Clinical interpretation of these findings is difficult since the optimal loading scenario for distal ulnar implant longevity remains unknown. Please contact author for diagrams and graphs.
A load cell, capable of measuring medial and lateral loads independently, was used to evaluate current methods of ligamentous balancing in total knee arthroplasty. Ten cadaveric knees were randomized with the surgeons blinded or unblinded to the load cell’s output. Before ligament resection, there were differences between medial and lateral forces (p<
0.05). Balance improved in both groups following ligamentous releases. There was a trend for superior balance (medial-lateral compressive force) with load cell feedback provided: 30°(11.1 vs. 44.4N), 60°(7.1 vs. 36.9N), and 90°(3.0 vs. 8.7N). Further in-vivo studies with this device may improve load transfer and the longevity of TKA. The purpose of this study was to employ a tibial load cell to assess current methods of ligamentous balance during total knee arthroplasty, and to determine whether the load cell can improve load distribution between the medial and lateral compartments. Current methods achieve imperfect load balance, however this may be improved with the assistance of an intra-operative load cell. Intra-operative assessment and quantification of load balance with a load cell may improve the longevity of TKA. TKA was performed on five pairs of cadaveric knees which were randomly assigned into one of two groups based upon whether the surgeons were blinded or unblinded to the load cell’s output. A validated tibial load cell, capable of measuring medial and lateral loads independently, was inserted. Compartment forces were recorded at discrete flexion angles prior to ligamentous balancing and again after soft tissue balancing with final components cemented into position. Initially, there were significant differences between the loads in the medial and lateral compartments (p<
0.05). With soft tissue release, there was improved balance. There was a trend for superior balance (medial minus lateral compressive force) in the unblinded group at 30°: 11.1N unblinded vs. 44.4N blinded, 60°: 7.1 vs. 36.9N, and 90°: 3.0 vs. 8.7N. Failure to achieve ligamentous balance results in instability and unequal load distribution. Current balancing techniques are not perfect, but appear to be improved with the use of the load cell. Further in-vitro and in-vivo studies are needed to improve the load distribution following TKA.