Aim of the study was to analyse the modifications of the pre-op and post-op femoral off-set after cementless total hip replacement. During an 18-month period, from January 2015 to June 2016, we retrospectively analysed data of 79 (n = 81 hips) patients (M:F = 31:48), with an average age of 70.38 yrs ± 10.05, who consecutively affered to our Department and underwent cementless total hip replacement for primary osteoarthritis with Pinnacle GriptionTM cup and CorailTM stem (Depuy). All cases of infections and revision surgery were excluded. Inclusion criteria: postero-lateral approach, 2 dedicated surgeons. All patients were clinically and radiographically evaluated at 4-months and 1-year postop. Preop and postop femoral off-set were calculated using Impax Agfa software. Average preop HHS was 46.7 ± 7.7; at 4-months post-op 86.4 ± 5.7; at 1-year post-op 90.0 ± 5 (the improvement had a statistically significant p-value). There was no statistical significant difference between the preop and postop off-set values obtained (t-student test). In 38 (46.9%) hips we increased the femoral off-set and we analysed using χ₂-test if there was a correlation with hip pain, HHS and dislocation. There was no statistical significance. Our overall results show good and excellent clinical results at 1 year follow-up in cementless total hip replacement. We believe that our pre-op digital planning of the implant and the offset obtained is a crucial step in determining these results.