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Orthopaedic Proceedings
Vol. 96-B, Issue SUPP_11 | Pages 326 - 326
1 Jul 2014
Mumme M Pelttari K Gueven S Nuss K Von Rechenberg B Jakob M Martin I Barbero A
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Summary

Nasal Chondrocytes are safe and feasible for tissue engineering approaches in articular cartilage repair.

Introduction

As compared to articular chondrocytes (AC), nasal septum chondrocytes (NC) proliferate faster and have a higher and more reproducible capacity to generate hyaline-like cartilaginous tissues. Moreover, the use of NC would allow reducing the morbidity associated with the harvesting of cartilage biopsy from the patient. The objective of the present study was to demonstrate safety and feasibility in the use of tissue engineered cartilage graft based on autologous nasal chondrocytes for the repair of articular defect in goats.