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Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_17 | Pages 74 - 74
1 Dec 2018
Meda M Penfold G Felstead AJ Sturridge S Hill P
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Aim

We report on the performance of a simple algorithm using a combination of synovial fluid White blood cell count(WBC), C-reactive protein(CRP) and α-Defensin(AD) tests to aid in the diagnosis of prosthetic joint infections.

Methods

Sixty-six synovial fluid samples were collected prospectively in patients with suspected PJI (hip and knee). All samples were tested by: WBC counts (read manually) and CRP test (Alere-Afinion™ validated in-house); and on 37 of these with AD test.

Synovial fluid samples were collected in 5 ml ethylenediaminetetraacetic acid (EDTA) tubes. Samples that were very viscous were pre-processed by the addition of 100µl of hyaluronidase solution. Grossly blood stained and clotted samples were excluded.

A clinical diagnosis of infection was based IDSA definitions1. Cut offs of >3000 × 106 cells/L for total synovial WBC count and >12mg/L for CRP were used to define infection2,3.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XL | Pages 79 - 79
1 Sep 2012
Vanhegan I Jassim S Sturridge S Ahir S Hua J Witt J Nielsen P Blunn G
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Introduction

A new conservative hip stem has been designed to address the complex problem of total hip arthroplasty in the younger population.

Objectives

To assess the stability and strain distribution of a new conservative hip stem.