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Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_1 | Pages 109 - 109
1 Feb 2020
Samuel L Rabin J Sultan A Arnold N Brooks P Mont M
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Introduction

Metal-on-Metal (MoM) bearing surfaces were historically used for young patients undergoing total hip arthroplasty, and remain commonplace in modern hip resurfacing. In theory, it has been postulated that metal ions released from such implants may cross the placental barrier and cause harm to the fetus. In light of this potential risk, recommendations against the use of MoM components in women of child-bearing age have been advocated. The purpose of this systematic review was to evaluate: 1) the Metal-on-Metal bearing types and ion levels found; 2) the concentrations of metals in maternal circulation and the umbilical cord; and 3) the presence of abnormalities in the fetus

Methods

A comprehensive literature review was conducted of studies published between January 1st, 1975 and April 1st, 2019 using specific keywords. (See Fig 1). We defined the inclusion criteria for qualifying studies for this review as follows: 1) studies that reported on the women who experienced pregnancy and who had a Metal-on-Metal hip implant; 2) studies that reported on maternal metal ions blood and umbilical cord levels; and 3) studies that reported on the occurrence of fetal complications. Data on cobalt and chromium ion levels in the maternal blood and umbilical cord blood, as well as the presence of adverse effects in the infant were collected. Age at parturition and time from MoM implant to parturition were also collected. A total of 6 studies were included in the final analysis that reported on a total of 21 females and 21 infants born. The mean age at parturition was 40 years (range, 24–41 years), and the mean time from MoM implantation to parturition was 47.2 months (range, 11–119 months).


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_2 | Pages 28 - 28
1 Feb 2020
Arnold N Samuel L Karnuta J Munim M Sultan A Kamath A
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Background

Standard preoperative protocols in total joint arthroplasty utilize the International Normalized Ratio (INR) to determine patient coagulation profiles. However, the relevance of preoperative INR values in joint arthroplasty remains controversial. Acceptable INR cutoff values for joint replacement are inconsistent, and are often based on studies of primary arthroplasty, or even non-orthopedic procedures. This analysis examined the relationship between preoperative INR values and post-operative outcomes in revision total hip arthroplasty (rTHA). Optimal cutoff INR values correlated with specific outcomes were subsequently determined.

Methods

The American College of Surgeons National Surgical Quality Improvement Program (NSQIP) was retrospectively queried for revision total hip arthroplasty procedures performed between 2006 and 2017. Patients with a preoperative INR collected no later than 1 day prior to surgery were further stratified for analysis. INR values which correlated with specific outcomes were determined using receiver operating characteristics (ROC) curves for each outcome of interest. The optimal cutoff INR value for each outcome was then obtained using univariate and multivariate models which determined INR values that maximized both sensitivity and specificity.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_2 | Pages 37 - 37
1 Feb 2020
Acuña A Samuel L Sultan A Kamath A
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Introduction

Acetabular dysplasia, also known as developmental dysplasia of the hip, has been shown to contribute to the onset of osteoarthritis. Surgical correction involves repositioning the acetabulum in order to improve coverage of the femoral head. However, ideal placement of the acetabular fragment can often be difficult due to inadequate visualization. Therefore, there has been an increased need for pre-operative planning and navigation modalities for this procedure.

Methods

PubMed and EBSCO Host databases were queried using keywords (preoperative, pre-op, preop, before surgery, planning, plan, operation, surgery, surgical, acetabular dysplasia, developmental dysplasia of the hip, and Hip Dislocation, Congenital [Mesh]) from 1974 to March 2019. The search generated 411 results. We included all case-series, English, full-text manuscripts pertaining to pre-operative planning for congenital acetabular dysplasia. Exclusion criteria included: total hip arthroplasty (THA) planning, patient population mean age over 35, and double and single case studies.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_2 | Pages 31 - 31
1 Feb 2020
Acuña A Samuel L Yao B Faour M Sultan A Kamath A Mont M
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Introduction

With an ongoing increase in total knee arthroplasty (TKA) procedural volume, there is an increased demand to improve surgical techniques to achieve ideal outcomes. Considerations of how to improve post-operative outcomes have included preservation of the infrapatellar fat pad (IPFP). Although this structure is commonly resected during TKA procedures, there is inconsistency in the literature and among surgeons regarding whether resection or preservation of the IPFP should be achieved. Additionally, information about how surgical handling of the IPFP influences outcomes is variable. Therefore, the purpose of this systematic review was to evaluate the influence of IPFP resection and preservation on post-operative flexion, pain, Insall-Salvati Ratio (ISR), Knee Society Score (KSS), patellar tendon length (PTL), and satisfaction in primary TKA.

Methods

A systematic literature search was performed to retrieve all reports that evaluated IPFP resection or preservation during total knee arthroplasty (TKA). The following databases were queried: PubMed, EBSCO host, and SCOPUS, resulting in 488 unique reports. Two reviewers independently reviewed the studies for eligibility based on pre-established inclusion and exclusion criteria. A total of 11 studies were identified for final analysis. Patient demographics, type of surgical intervention, follow-up duration, and clinical outcome measures were collected and further analyzed. This systematic review reported on 11,996 total cases. Complete resection was implemented in 3,723 cases (31%), partial resection in 5,458 cases (45.5%), and preservation of the IPFP occurred in 2,815 cases (23.5%). Clinical outcome measures included patellar tendon length (PTL) (5 studies), knee flexion (4 studies), pain (6 studies), Knee Society Score (KSS) (3 studies), Insall-Salvati Ratio (ISR) (3 studies), and patient satisfaction (1 study).


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_1 | Pages 58 - 58
1 Jan 2018
Newman J Khlopas A Sodhi N Curtis G Sultan A Higuera C Mont M
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Patients who have multiple sclerosis (MS) may be at increased risk of developing complications after total hip arthroplasty (THA). The purpose of this study was to compare: 1) implant survivorship; 2) functional outcomes; 3) complication rates; and 4) radiographic findings after THA between MS patients and a matched cohort.

A single institutional database was reviewed for patients who had a diagnosis of MS and underwent a THA. Thirty-four patients (41 hips) were matched to a 2:1 cohort who did not have MS using based on age, sex, body mass index (BMI), and Charlson/Deyo scores. This resulted in a matching cohort of 80 patients (82 hips). The available medical records were reviewed. Functional outcomes and complications were assessed. Postoperative radiographs were evaluated.

The matching cohort had higher all-cause survivorship at 4-years postoperatively (99 vs. 93%). There were 3 revisions in the MS cohort and 0 revisions in the matching cohort. The MS cohort had lower mHHS scores (66 vs.74 points, p<0.001), lower HOOS JR scores (79 vs. 88 points, p<0.01), required more physical therapy (5 vs. 3 weeks, p<0.01), and took longer to return to their baseline functional level (7 vs. 5 weeks, p<0.05). MS patients had higher rate of complications (6 vs. 1, p<0.05). Excluding revision cases, there was no additional radiographic evidence of progressive radiolucency, loosening, or subsidence.

We found that MS patients had lower implant survivorship, lower functional outcome scores, and increased complication rates. These findings may help orthopaedists to have a better knowledge of how MS patients do after THA.