Aims: The aim of this study is to evaluate the effectiveness of a treatment with botulinum toxin type A (BTX-A) in children affected by CP. Methods: Between May 2001 and July 2002, we treated 12 children affected by CP: 11 males, 1 female, mean age 6,42 years; 1 child suffered from tetraplegia, 5 from diplegia and 6 from emiplegia. The injection was carried out in gastrocne-mius muscle (medial and lateral) in 11 patients, in hamstrings in 1 patients in a dose of 6 Units per kg of body weight per muscle. Post-injective treatment included intense physical therapy and orthoses. A clinical and video-recording evaluation, Gross scale and gait-EMG were carried out before injection and 1,3,6 months after. Results: BTX-A treatment has a good functional result: at the þrst control after injection all patients had a complete foot-ground contact instead of toe contact during stance and gait. Conclusion: The results of BTX-A treatment are positive, accordingly to literature: in all patients there was a reduction of spasticity and a complete foot-ground contact, with functional improvement in stance and gait. Good results can be achieved only if the indication is correct: spasticity of the muscle without muscle-tendinous retraction. BTX-A treatment has an effective role in the management of children suffering from CP, where there is no indication for surgical treatment.