Joint registries suggest a downward trend in the use of uncemented Total Knee Replacements (TKR) since 2003, largely related to reports of early failures of uncemented tibial and patella components. Advancements in uncemented design such as trabecular metal may improve outcomes, but there is a scarcity of high-quality data from randomised trials. 319 patients <75 years of age were randomised to either cemented or uncemented TKR implanted using computer navigation. Patellae were resurfaced in all patients. Patient outcome scores, re-operations and radiographic analysis of radiolucent lines were compared. Two year follow up was available for 287 patients (144 cemented vs 143 uncemented). There was no difference in operative time between groups, 73.7 v 71.1 mins (p= 0.08). There were no statistical differences in outcome scores at 2 years, Oxford knee score 42.5 vs 41.8 (p=0.35), International Knee Society 84.6 vs 84.0 (p=0.76), Forgotten Joint Score 66.7 vs 66.4 (p=0.91). There were two revisions, both for infection one in each group (0.33%). 13 cemented and 8 uncemented knees underwent re-operation, the majority of these being manipulation under anaesthetic (85.7%), with no difference (8.3% vs 5.3%, 95% CI -2.81% to 8.89%, p = 0.31). No difference was found in radiographic analysis at 2 years, 1 lucent line was seen in the cemented group and 3 in the uncemented group (0.67% v 2.09%, 95%CI -4.1% to 1.24%, p = 0.29). We found no difference in clinical or radiographic outcomes between cemented and uncemented TKR including routine patella resurfacing at two years. Early results suggest there is no difference between cemented and uncemented TKR at 2 years with reference to survivorship, patient outcomes and radiological parameters.
The study was conducted to investigate differences between simultaneous and sequential cementing of the tibial and femoral components in total knee joint replacements. Our hypothesis was that cementing the components sequentially increases accuracy of the final position. This was a prospective and randomized study, performed using a computer navigation system as the evaluation technique to determine the accuracy of implant positioning. All knee replacements (Scorpio, Stryker) were implanted using navigation technique. The patients were divided in two groups. The first group had implants cemented simultaneously where the tibial and femoral components were implanted with a single mix of cement and then pressurized by extending the leg. The second group of patients had the tibial component inserted with the first mix of cement and then impacted. The cement was allowed to set before proceeding with insertion of the femoral component using a second mix of cement. The computer navigation system was utilized for bone cuts. It was then used to measure 3 sets of angles. The first set was varus/valgus cut of the femur, varus/valgus cut of the tibia and posterior slope of the tibia. The second set of measurements were the same angles, this time of the position of the prosthetic components before cementing, and the third set after cementing. Our interim results show just a small difference between the two techniques. It does not appear there is substantial difference in positioning of the implants between these two different techniques.