Our objective was to examine the rate of revision
and its predictive factors in patients undergoing total shoulder arthroplasty
(TSA). We used prospectively collected data from the Mayo Clinic
Total Joint Registry to examine five-, ten- and 20-year revision-free
survival following TSA and the predictive factors. We examined patient
characteristics (age, gender, body mass index, comorbidity), implant
fixation (cemented versus uncemented), American
Society of Anesthesiologists class and underlying diagnosis. Univariate
and multivariable adjusted hazard rates were calculated using Cox
regression analysis. A total of 2207 patients underwent 2588 TSAs.
Their mean age was 65.0 years (19 to 91) and 1163 (53%) were women;
osteoarthritis was the underlying diagnosis in 1640 shoulders (63%). In
all, 212 TSAs (8.2%) were revised during the follow-up period. At
five, ten and 20 years, survival rates were 94.2% (95% confidence
interval (CI) 93.2 to 95.3), 90.2% (95% CI 88.7 to 91.7) and 81.4%
(95% CI 78.4 to 84.5), respectively. In multivariable analyses men
had a higher hazard ratio of revision of 1.72 (95% CI 1.28 to 2.31)
(p <
0.01) compared with women, and those with rotator cuff disease
had a hazard ratio of 4.71 (95% CI 2.09 to 10.59) (p <
0.001) compared
with patients with rheumatoid arthritis. We concluded that male
gender and rotator cuff disease are independent risk factors for
revision after TSA. Future studies are needed to understand the
biological rationale for these differences.