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The Bone & Joint Journal
Vol. 101-B, Issue 7_Supple_C | Pages 91 - 97
1 Jul 2019
Chalmers BP Weston JT Osmon DR Hanssen AD Berry DJ Abdel MP

Aims

There is little information regarding the risk of a patient developing prosthetic joint infection (PJI) after primary total knee arthroplasty (TKA) when the patient has previously experienced PJI of a TKA or total hip arthroplasty (THA) in another joint. The goal of this study was to compare the risk of PJI of primary TKA in this patient population against matched controls.

Patients and Methods

We retrospectively reviewed 95 patients (102 primary TKAs) treated between 2000 and 2014 with a history of PJI in another TKA or THA. A total of 50 patients (53%) were female. Mean age was 69 years (45 to 88) with a mean body mass index (BMI) of 36 kg/m2 (22 to 59). In total, 27% of patients were on chronic antibiotic suppression. Mean follow-up was six years (2 to 16). We 1:3 matched these (for age, sex, BMI, and surgical year) to 306 primary TKAs performed in 306 patients with a THA or TKA of another joint without a subsequent PJI. Competing risk with death was used for statistical analysis. Multivariate analysis was followed to evaluate risk factors for PJI in the study cohort.


Bone & Joint Research
Vol. 8, Issue 3 | Pages 126 - 135
1 Mar 2019
Sekiguchi K Nakamura S Kuriyama S Nishitani K Ito H Tanaka Y Watanabe M Matsuda S

Objectives

Unicompartmental knee arthroplasty (UKA) is one surgical option for treating symptomatic medial osteoarthritis. Clinical studies have shown the functional benefits of UKA; however, the optimal alignment of the tibial component is still debated. The purpose of this study was to evaluate the effects of tibial coronal and sagittal plane alignment in UKA on knee kinematics and cruciate ligament tension, using a musculoskeletal computer simulation.

Methods

The tibial component was first aligned perpendicular to the mechanical axis of the tibia, with a 7° posterior slope (basic model). Subsequently, coronal and sagittal plane alignments were changed in a simulation programme. Kinematics and cruciate ligament tensions were simulated during weight-bearing deep knee bend and gait motions. Translation was defined as the distance between the most medial and the most lateral femoral positions throughout the cycle.


The Bone & Joint Journal
Vol. 101-B, Issue 6_Supple_B | Pages 739 - 744
1 Jun 2019
Tsagozis P Laitinen MK Stevenson JD Jeys LM Abudu A Parry MC

Aims

The aim of this study was to identify factors that determine outcomes of treatment for patients with chondroblastic osteosarcomas (COS) of the limbs and pelvis.

Patients and Methods

The authors carried out a retrospective review of prospectively collected data from 256 patients diagnosed between 1979 and 2015. Of the 256 patients diagnosed with COS of the pelvis and the limbs, 147 patients (57%) were male and 109 patients (43%) were female. The mean age at presentation was 20 years (0 to 90).


The Journal of Bone & Joint Surgery British Volume
Vol. 53-B, Issue 3 | Pages 488 - 494
1 Aug 1971
Aichroth P Branfoot AC Huskisson EC Loughridge LW

1. Destructive changes in a knee joint, eventually requiring arthrodesis, are reported in a patient who had undergone renal transplantation. 2. The underlying pathology was avascular necrosis with separation of large osteochondral fragments. 3. The pathogenesis is discussed


The Journal of Bone & Joint Surgery British Volume
Vol. 51-B, Issue 3 | Pages 506 - 507
1 Aug 1969
Rifaat MA Massoud AF Shafie MB

1. A case of traumatic aneurysm of the descending genicular artery complicating elective operation on the knee joint is reported. 2. The aneurysm was mainly intra-articular, presenting as a pulsating haemarthrosis soon after operation. 3. The pathogenesis, symptomatology, diagnosis and management are briefly discussed


Objectives

Bioresorbable orthopaedic devices with calcium phosphate (CaP) fillers are commercially available on the assumption that increased calcium (Ca) locally drives new bone formation, but the clinical benefits are unknown. Electron beam (EB) irradiation of polymer devices has been shown to enhance the release of Ca. The aims of this study were to: 1) establish the biological safety of EB surface-modified bioresorbable devices; 2) test the release kinetics of CaP from a polymer device; and 3) establish any subsequent beneficial effects on bone repair in vivo.

Methods

ActivaScrew Interference (Bioretec Ltd, Tampere, Finland) and poly(L-lactide-co-glycolide) (PLGA) orthopaedic screws containing 10 wt% β-tricalcium phosphate (β-TCP) underwent EB treatment. In vitro degradation over 36 weeks was investigated by recording mass loss, pH change, and Ca release. Implant performance was investigated in vivo over 36 weeks using a lapine femoral condyle model. Bone growth and osteoclast activity were assessed by histology and enzyme histochemistry.


The Journal of Bone & Joint Surgery British Volume
Vol. 58-B, Issue 4 | Pages 511 - 512
1 Nov 1976
Ackroyd C Dinley R

Mechanical derangements of the knee are an uncommon complication of chronic haemophiliac arthropathy. Two patients with locking of the patella were treated by manipulation. The mechanism of the injury was forced flexion of the knee joint beyond the limit of its restricted range. The injury is a serious one and may take six months to recover


The Journal of Bone & Joint Surgery British Volume
Vol. 32-B, Issue 3 | Pages 302 - 306
1 Aug 1950
Isserlin B

Joint débridement, by excision of synovial membrane, osteophytes, degenerate cartilage, loose bodies, and frequently the patella, has relieved the symptoms of osteoarthritis of the knee joint twenty-three times in a series of thirty-five operations reviewed after periods of one to nine years. The operation is considered a useful measure when symptoms resist conservative treatment


The Journal of Bone & Joint Surgery British Volume
Vol. 52-B, Issue 1 | Pages 124 - 127
1 Feb 1970
Barfod B Michael D

Two cases of laterally open knee joints with surrounding skin defects are reported. The joints were closed by muscle flaps fashioned from the lateral belly of the gastrocnemius, which was detached distally and folded upwards and forwards to cover the defect. The transposed muscle and the remainder of the wound were covered by free skin grafts. Results were satisfactory


The Journal of Bone & Joint Surgery British Volume
Vol. 42-B, Issue 4 | Pages 730 - 735
1 Nov 1960
Somerville EW

1. The nature of flexion contractures of the knee joint is discussed. 2. It is suggested that division of the anterior cruciate ligament will help in the correction of the deformity when conservative methods have failed. 3. The results of the treatment of twelve such knees are mentioned and illustrative cases are described. 4. It must be emphasised that this method of treatment should be undertaken only when conservative methods have failed


The Journal of Bone & Joint Surgery British Volume
Vol. 30-B, Issue 1 | Pages 106 - 109
1 Feb 1948
Jones GB

1. The behaviour of penicillin injected locally into knee joints is investigated and found to be the only satisfactory way of using the drug in joint wounds and infections. 2. Penicillin persists within the joint for forty-eight hours after injection unless the effusion is being actively absorbed. 3. The additional administration of penicillin by intramuscular injection is recommended when other considerations demand it


The Journal of Bone & Joint Surgery British Volume
Vol. 67-B, Issue 4 | Pages 572 - 575
1 Aug 1985
Thomas N Jackson A Aichroth P

The clinical and radiological features of 12 knees (10 patients) with congenital absence of the anterior cruciate ligament are presented. The high frequency of this condition in association with other more easily recognised congenital abnormalities of the knee is discussed. It is concluded that congenital absence of the anterior cruciate ligament is more common than generally suspected and is associated with other developmental abnormalities of both bone and soft tissue in the lower limb, particularly around the knee joint


The Journal of Bone & Joint Surgery British Volume
Vol. 72-B, Issue 2 | Pages 231 - 234
1 Mar 1990
Chow S Lam J Leong J

We have reviewed 16 patients with avulsion fractures of the tibial tubercle, mostly boys who sustained left-sided injuries during sport. Two-thirds had type I or II injuries and were treated conservatively. Fractures involving the knee joint (type III) had internal fixation. The final results were good except for minor complications such as a prominent and uncomfortable tibial tubercle


The Journal of Bone & Joint Surgery British Volume
Vol. 50-B, Issue 3 | Pages 493 - 504
1 Aug 1968
Brookes M Helal B

1. The venographic findings in clinical primary osteoarthritis are described. 2. Experimental venous engorgement, of the knee joint and of healing fibular fractures, results in accelerated bone formation and disturbed cartilage formation. 3. Changes in pH, ppCO. 2. , and PPO. 2. are indicated as the chemical means by which chondrogenesis and osteogenesis can be altered. 4. It is suggested that chronic venous stress in joints is a causal factor in primary osteoarthritis


The Journal of Bone & Joint Surgery British Volume
Vol. 43-B, Issue 1 | Pages 87 - 89
1 Feb 1961
Maudsley RH Arden GP

1. Three cases are described of a calf swelling occurring in rheumatoid arthritis. 2. This condition has been described by Baker, though many of his patients had tuberculous infection of the knee. 3. The diagnosis may present difficulty because of the distance of the swelling from its origin in the knee joint. 4. Excision of the cyst is advised when it causes pain, but recurrence is likely if disease of the joint remains active


Bone & Joint Research
Vol. 7, Issue 12 | Pages 639 - 649
1 Dec 2018
MacLeod AR Serrancoli G Fregly BJ Toms AD Gill HS

Objectives

Opening wedge high tibial osteotomy (HTO) is an established surgical procedure for the treatment of early-stage knee arthritis. Other than infection, the majority of complications are related to mechanical factors – in particular, stimulation of healing at the osteotomy site. This study used finite element (FE) analysis to investigate the effect of plate design and bridging span on interfragmentary movement (IFM) and the influence of fracture healing on plate stress and potential failure.

Materials and Methods

A 10° opening wedge HTO was created in a composite tibia. Imaging and strain gauge data were used to create and validate FE models. Models of an intact tibia and a tibia implanted with a custom HTO plate using two different bridging spans were validated against experimental data. Physiological muscle forces and different stages of osteotomy gap healing simulating up to six weeks postoperatively were then incorporated. Predictions of plate stress and IFM for the custom plate were compared against predictions for an industry standard plate (TomoFix).


The Journal of Bone & Joint Surgery British Volume
Vol. 54-B, Issue 2 | Pages 360 - 370
1 May 1972
Galway RD Cruess RL

Subtotal synovectomy was performed in the knee joints of New Zealand white rabbits. The changes noted in the articular cartilage as manifest by decreased metachromatic staining of the matrix were considered to indicate matrix degradation caused by the altered joint environment. The documentation of the enzyme changes suggests that the histological alteration in the articular cartilage noted after synovectomy may be mediated through the activation of endogenous chondrocyte lysozomal enzymes, particularly cathepsin and acid hydrolases


The Journal of Bone & Joint Surgery British Volume
Vol. 69-B, Issue 5 | Pages 693 - 695
1 Nov 1987
Barrie H

In 1887, Konig claimed that loose bodies in the knee joints of young persons had three causes: (1) very severe trauma; (2) lesser trauma causing contusion and necrosis; and (3) minimal trauma acting on an underlying lesion-for which he suggested the name osteochondritis dissecans. His thesis has stood the test of time. We still confuse the second and third categories but osteochondritis dissecans has been identified as an ossification defect


The Bone & Joint Journal
Vol. 101-B, Issue 5 | Pages 522 - 528
1 May 2019
Medellin MR Fujiwara T Clark R Stevenson JD Parry M Jeys L

Aims

The aim of this study was to evaluate the prosthesis characteristics and associated conditions that may modify the survival of total femoral endoprosthetic replacements (TFEPR).

Patients and Methods

In all, 81 patients treated with TFEPR from 1976 to 2017 were retrospectively evaluated and failures were categorized according to the Henderson classification. There were 38 female patients (47%) and 43 male patients (53%) with a mean age at diagnosis of 43 years (12 to 86). The mean follow-up time was 10.3 years (0 to 31.7). A survival analysis was performed followed by univariate and multivariate Cox regression to identify independent implant survival factors.


The Journal of Bone & Joint Surgery British Volume
Vol. 48-B, Issue 1 | Pages 56 - 63
1 Feb 1966
Mann TS

1. Five elderly patients who suffered acute synovitis of one or both knee joints are reported. 2. All showed radiological evidence in several joints of cartilage calcification. 3. It is suggested that the synovitis in each case was due to calcium irritation of the synovial membrane. 4. In three of the patients it is shown that the synovial fluid calcium content was raised during the acute attack. 5. In all patients acute symptoms were relieved by aspiration of the effusion