A total of 219 hips in 192 patients aged between
18 and 65 years were randomised to 28-mm metal-on-metal uncemented
total hip replacements (THRs, 107 hips) or hybrid hip resurfacing
(HR, 112 hips). At a mean follow-up of eight years (6.6 to 9.3)
there was no significant difference between the THR and HR groups
regarding rate of revision (4.0% (4 of 99) vs 5.8%
(6 of 104), p = 0.569) or re-operation rates without revision (5.1%
(5 of 99) vs 2.9% (3 of 104), p = 0.428). In the
THR group one recurrent dislocation, two late deep infections and
one peri-prosthetic fracture required revision, whereas in the HR
group five patients underwent revision for femoral head loosening
and one for adverse reaction to metal debris. The mean University
of California, Los Angeles activity scores were significantly higher
in HR (7.5 (sd 1.7) vs 6.9 (sd 1.7),
p = 0.035), but similar mean Western Ontario and McMaster Universities Osteoarthritis
Index scores were obtained (5.8 (sd 9.5) in HR vs 5.1
(sd 8.9) in THR, p = 0.615) at the last follow-up. Osteolysis
was found in 30 of 81 THR patients (37.4%), mostly in the proximal
femur, compared with two of 83 HR patients (2.4%) (p <
0.001).
At five years the mean metal ion levels were <
2.5 μg/l for cobalt
and chromium in both groups; only titanium was significantly higher
in the HR group (p = 0.001). Although revision rates and functional scores
were similar in both groups at mid-term, long-term survival analysis
is necessary to determine whether one procedure is more advantageous
than the other.
Cite this article: Bone Joint J 2013;95-B:1464–73.