There is conflicting evidence about the merits
of mobile bearings in total knee replacement, partly because most randomised
controlled trials (RCTs) have not been adequately powered. We report
the results of a multicentre RCT of mobile versus fixed
bearings. This was part of the knee arthroplasty trial (KAT), where
539 patients were randomly allocated to mobile or fixed bearings
and analysed on an intention-to-treat basis. The primary outcome measure
was the Oxford Knee Score (OKS) plus secondary measures including
Short Form-12, EuroQol EQ-5D, costs, cost-effectiveness and need
for further surgery.
There was no significant difference between the groups pre-operatively:
mean OKS was 17.18 (sd 7.60) in the mobile-bearing group
and 16.49 (sd 7.40) in the fixed-bearing group. At five
years mean OKS was 33.19 (sd 16.68) and 33.65 (sd 9.68),
respectively. There was no significant difference between trial
groups in OKS at five years (-1.12 (95% confidence interval -2.77
to 0.52) or any of the other outcome measures. Furthermore, there
was no significant difference in the proportion of patients with
knee-related re-operations or in total costs.
In this appropriately powered RCT, over the first five years
after total knee replacement functional outcomes, re-operation rates
and healthcare costs appear to be the same irrespective of whether
a mobile or fixed bearing is used.
Cite this article: Bone Joint J 2013;95-B:486–92.