We tested four types of surgical
repair for load to failure and distraction in a bovine model of
Achilles tendon repair. A total of 20 fresh bovine Achilles tendons
were divided transversely 4 cm proximal to the calcaneal insertion
and randomly repaired using the Dresden technique, a Krackow suture,
a triple-strand Dresden technique or a modified oblique Dresden
technique, all using a Fiberwire suture. Each tendon was loaded
to failure. The force applied when a 5 mm gap was formed, peak load
to failure, and mechanism of failure were recorded. The resistance
to distraction was significantly greater for the triple technique
(mean 246.1 N (205 to 309) to initial gapping) than for the Dresden (mean
180 N (152 to 208); p = 0.012) and the Krackow repairs (mean 101
N (78 to 112; p <
0.001). Peak load to failure was significantly
greater for the triple-strand repair (mean 675 N (453 to 749)) than
for the Dresden (mean 327.8 N (238 to 406); p <
0.001), Krackow
(mean 223.6 N (210 to 252); p <
0.001) and oblique repairs (mean
437.2 N (372 to 526); p <
0.001). Failure of the tendon was the
mechanism of failure for all specimens except for the tendons sutured using
the Krackow technique, where the failure occurred at the knot. The triple-strand technique significantly increased the tensile
strength (p = 0.0001) and gap resistance (p = 0.01) of bovine tendon
repairs, and might have advantages in
This study describes the Osseointegration Group of Australia’s
Accelerated Protocol two-stage strategy (OGAAP-1) for the osseointegrated
reconstruction of amputated limbs. We report clinical outcomes in 50 unilateral trans-femoral amputees
with a mean age of 49.4 years (24 to 73), with a minimum one-year
follow-up. Outcome measures included the Questionnaire for persons
with a Trans-Femoral Amputation, the health assessment questionnaire
Short-Form-36 Health Survey, the Amputation Mobility Predictor scores
presented as K-levels, 6 Minute Walk Test and timed up and go tests.
Adverse events included soft-tissue problems, infection, fractures
and failure of the implant.Aims
Patients and Methods
A silver-containing hydroxyapatite (Ag-HA) coating has been developed using thermal spraying technology. We evaluated the osteoconductivity of this coating on titanium (Ti) implants in rat tibiae in relation to bacterial infection in joint replacement. At 12 weeks, the mean affinity indices of bone formation of a Ti, an HA, a 3%Ag-HA and a 50%Ag-HA coating were 97.3%, 84.9%, 81.0% and 40.5%, respectively. The mean affinity indices of bone contact of these four coatings were 18.8%, 83.7%, 77.2% and 40.5%, respectively. The indices of bone formation and bone contact around the implant of the 3%Ag-HA coating were similar to those of the HA coating, and no significant differences were found between them (bone formation, p = 0.99; bone contact, p = 0.957). However, inhibition of bone formation was observed with the 50%Ag-HA coating. These results indicate that the 3%Ag-HA coating has low toxicity and good osteoconductivity, and that the effect of silver toxicity on osteoconductivity depends on the dose.
We compared lower limb coronal alignment measurements
obtained pre- and post-operatively with long-leg radiographs and
computer navigation in patients undergoing primary total knee replacement
(TKR). A series of 185 patients had their pre- and post-implant
radiological and computer-navigation system measurements of coronal alignment
compared using the Bland-Altman method. The study included 81 men
and 104 women with a mean age of 68.5 years (32 to 87) and a mean
body mass index of 31.7 kg/m2 (19 to 49). Pre-implant
Bland–Altman limits of agreement were -9.4° to 8.6° with a repeatability
coefficient of 9.0°. The Bland–Altman plot showed a tendency for the
radiological measurement to indicate a higher level of pre-operative
deformity than the corresponding navigation measurement. Post-implant
limits of agreement were -5.0° to 5.4° with a repeatability coefficient
of 5.2°. The tendency for valgus knees to have greater deformity
on the radiograph was still seen, but was weaker for varus knees. The alignment seen or measured intra-operatively during TKR is
not necessarily the same as the deformity seen on a standing long-leg
radiograph either pre- or post-operatively. Further investigation
into the effect of weight-bearing and surgical exposure of the joint
on the mechanical femorotibial angle is required to enable the most appropriate
intra-operative alignment to be selected.